المؤلفون: Canton, APM, Tinano, FR, Guasti, L, Montenegro, LR, Ryan, F, Shears, D, De Melo, ME, Gomes, LG, Piana, MP, Brauner, R, Espino-Aguilar, R, Escribano-Muñoz, A, Paganoni, A, Read, JE, Korbonits, M, Seraphim, CE, Costa, SS, Krepischi, AC, Jorge, AAL, David, A, Kaisinger, LR, Ong, KK, Perry, JRB, Abreu, AP, Kaiser, UB, Argente, J, Mendonca, BB, Brito, VN, Howard, SR, Latronico, AC

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1032::981b647315e001185c5a099e2110c3b2
http://hdl.handle.net/10044/1/105145

المؤلفون: M. Gryngarten, Seraphim Ce, Ortiz-Cabrera Nv, Macedo Db, Ana Paula Abreu, Cunha M, A. C. Latronico, Piovesan Mr, Travieso-Suarez L, Carolina Ramos, V. N. Brito, Soriano-Guillen L, Argente J, de Castro Leal A, Labarta Ji, Antonini, Ursula B. Kaiser, Luciana Ribeiro Montenegro, B. B. Mendonca, Arcari Aj, Escribano Munoz A, Canton Apm, Corripio R, Guimaraes A, Gagliardi Pc, Benedetti Aff

المصدر: Yearbook of Paediatric Endocrinology.

مصطلحات موضوعية: medicine.medical_specialty, Endocrinology, Internal medicine, Central precocious puberty, medicine, Biology, Genotype-Phenotype Correlations

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9ebf1d44790211748c6d3368e2fffd5f
https://doi.org/10.1530/ey.18.7.2

المؤلفون: Canton APM; Developmental Endocrinology Unit, Hormones and Molecular Genetics Laboratory LIM/42, Clinicas Hospital, Discipline of Endocrinology and Metabolism, School of Medicine, University of Sao Paulo, 05403-000 Sao Paulo, Brazil.; Cellular and Molecular Endocrinology Laboratory LIM/25, Clinicas Hospital, Discipline of Endocrinology and Metabolism, School of Medicine, University of Sao Paulo, 01246-903 Sao Paulo, Brazil., Seraphim CE; Developmental Endocrinology Unit, Hormones and Molecular Genetics Laboratory LIM/42, Clinicas Hospital, Discipline of Endocrinology and Metabolism, School of Medicine, University of Sao Paulo, 05403-000 Sao Paulo, Brazil.; Cellular and Molecular Endocrinology Laboratory LIM/25, Clinicas Hospital, Discipline of Endocrinology and Metabolism, School of Medicine, University of Sao Paulo, 01246-903 Sao Paulo, Brazil., Montenegro LR; Developmental Endocrinology Unit, Hormones and Molecular Genetics Laboratory LIM/42, Clinicas Hospital, Discipline of Endocrinology and Metabolism, School of Medicine, University of Sao Paulo, 05403-000 Sao Paulo, Brazil.; Cellular and Molecular Endocrinology Laboratory LIM/25, Clinicas Hospital, Discipline of Endocrinology and Metabolism, School of Medicine, University of Sao Paulo, 01246-903 Sao Paulo, Brazil., Krepischi ACV; Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of Sao Paulo, 05508-090 Sao Paulo, Brazil., Mendonca BB; Developmental Endocrinology Unit, Hormones and Molecular Genetics Laboratory LIM/42, Clinicas Hospital, Discipline of Endocrinology and Metabolism, School of Medicine, University of Sao Paulo, 05403-000 Sao Paulo, Brazil.; Laboratório de Sequenciamento em Larga Escala (SELA), Faculdade de Medicina da Universidade de São Paulo, 01246-903 Sao Paulo, Brazil., Latronico AC; Developmental Endocrinology Unit, Hormones and Molecular Genetics Laboratory LIM/42, Clinicas Hospital, Discipline of Endocrinology and Metabolism, School of Medicine, University of Sao Paulo, 05403-000 Sao Paulo, Brazil.; Cellular and Molecular Endocrinology Laboratory LIM/25, Clinicas Hospital, Discipline of Endocrinology and Metabolism, School of Medicine, University of Sao Paulo, 01246-903 Sao Paulo, Brazil., Brito VN; Developmental Endocrinology Unit, Hormones and Molecular Genetics Laboratory LIM/42, Clinicas Hospital, Discipline of Endocrinology and Metabolism, School of Medicine, University of Sao Paulo, 05403-000 Sao Paulo, Brazil.

المصدر: European journal of endocrinology [Eur J Endocrinol] 2024 Jun 05; Vol. 190 (6), pp. 479-488.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9423848 Publication Model: Print Cited Medium: Internet ISSN: 1479-683X (Electronic) Linking ISSN: 08044643 NLM ISO Abbreviation: Eur J Endocrinol Subsets: MEDLINE

مواضيع طبية MeSH: Puberty, Precocious*/genetics , Puberty, Precocious*/etiology , Puberty, Precocious*/epidemiology, Humans ; Female ; Male ; Child ; Retrospective Studies ; Child, Preschool ; Magnetic Resonance Imaging ; Ribonucleoproteins/genetics ; Cohort Studies ; Ubiquitin-Protein Ligases/genetics ; Mutation ; Brain/diagnostic imaging

المؤلفون: Canton APM; Developmental Endocrinology Unit, Laboratory of Hormones and Molecular Genetics LIM/42, University of Sao Paulo, Sao Paulo, Brazil., Tinano FR; Developmental Endocrinology Unit, Laboratory of Hormones and Molecular Genetics LIM/42, University of Sao Paulo, Sao Paulo, Brazil., Guasti L; Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Montenegro LR; Developmental Endocrinology Unit, Laboratory of Hormones and Molecular Genetics LIM/42, University of Sao Paulo, Sao Paulo, Brazil., Ryan F; Oxford Children's Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Shears D; Oxford Centre for Genomic Medicine, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., de Melo ME; League of Childhood Obesity, University of Sao Paulo, Sao Paulo, Brazil., Gomes LG; Developmental Endocrinology Unit, Laboratory of Hormones and Molecular Genetics LIM/42, University of Sao Paulo, Sao Paulo, Brazil., Piana MP; Children's State Hospital of Vila Velha, Vila Velha, Brazil., Brauner R; Fondation Ophtalmologique Adolphe de Rothschild and Université de Paris, Paris, France., Espino-Aguilar R; Hospital Universitario Virgen de Valmes, Universidad de Sevilla, Sevilla, Spain., Escribano-Muñoz A; Endocrinology Unit, Department of Pediatrics, Virgen de la Arrixaca University Hospital, Murcia, Spain., Paganoni A; Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Read JE; Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Korbonits M; Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Seraphim CE; Developmental Endocrinology Unit, Laboratory of Hormones and Molecular Genetics LIM/42, University of Sao Paulo, Sao Paulo, Brazil., Costa SS; Discipline of Endocrinology and Metabolism, Clinicas Hospital, School of Medicine and Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of Sao Paulo, Sao Paulo, Brazil., Krepischi AC; Discipline of Endocrinology and Metabolism, Clinicas Hospital, School of Medicine and Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of Sao Paulo, Sao Paulo, Brazil., Jorge AAL; Genetic Endocrinology Unit LIM/25, University of Sao Paulo, Sao Paulo, Brazil., David A; Centre for Integrative Systems Biology and Bioinformatics, Department of Life Sciences, Imperial College London, London, UK., Kaisinger LR; Medical Research Council Epidemiology Unit, Wellcome-Medical Research Council Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK., Ong KK; Medical Research Council Epidemiology Unit, Wellcome-Medical Research Council Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK., Perry JRB; Medical Research Council Epidemiology Unit, Wellcome-Medical Research Council Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK., Abreu AP; Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Kaiser UB; Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Argente J; Department of Pediatrics, Universidad Autónoma de Madrid, Madrid, Spain; Department of Pediatrics and Pediatric Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, IMDEA Food Institute, Madrid, Spain., Mendonca BB; Developmental Endocrinology Unit, Laboratory of Hormones and Molecular Genetics LIM/42, University of Sao Paulo, Sao Paulo, Brazil., Brito VN; Developmental Endocrinology Unit, Laboratory of Hormones and Molecular Genetics LIM/42, University of Sao Paulo, Sao Paulo, Brazil., Howard SR; Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK; Department of Paediatric Endocrinology, Barts Health NHS Trust, London, UK., Latronico AC; Developmental Endocrinology Unit, Laboratory of Hormones and Molecular Genetics LIM/42, University of Sao Paulo, Sao Paulo, Brazil. Electronic address: anacl@usp.br.

المصدر: The lancet. Diabetes & endocrinology [Lancet Diabetes Endocrinol] 2023 Aug; Vol. 11 (8), pp. 545-554. Date of Electronic Publication: 2023 Jun 26.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: The Lancet, Diabetes & Endocrinology Country of Publication: England NLM ID: 101618821 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-8595 (Electronic) Linking ISSN: 22138587 NLM ISO Abbreviation: Lancet Diabetes Endocrinol Subsets: MEDLINE

مواضيع طبية MeSH: Puberty, Precocious*/genetics , Puberty, Precocious*/diagnosis , Rett Syndrome*/genetics , Rett Syndrome*/complications, Animals ; Child ; Female ; Humans ; Male ; Mice ; Brazil ; Cohort Studies ; Follicle Stimulating Hormone ; Gonadotropin-Releasing Hormone ; Luteinizing Hormone/metabolism

المؤلفون: Tinano FR; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, 05403-900 São Paulo, Brasil., Canton APM; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, 05403-900 São Paulo, Brasil., Montenegro LR; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, 05403-900 São Paulo, Brasil., de Castro Leal A; Departamento de Saúde Integrada, Universidade do Estado do Pará (UEPA), Santarém, 68040-090 Pará, Brasil., Faria AG; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, 05403-900 São Paulo, Brasil., Seraphim CE; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, 05403-900 São Paulo, Brasil., Brauner R; Pediatric Endocrinology Unit, Fondation Ophtalmologique Adolphe de Rothschild and Université Paris Descartes, 75019 Paris, France., Jorge AA; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, 05403-900 São Paulo, Brasil.; Unidade de Endocrinologia Genética, Laboratório de Endocrinologia Celular e Molecular LIM/25, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, 05403-900 São Paulo, Brasil., Mendonca BB; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, 05403-900 São Paulo, Brasil., Argente J; Department of Pediatrics, Universidad Autónoma de Madrid, 28049 Madrid, Spain.; Departments of Paediatrics and Paediatric Endocrinology, Hospital Infantil Universitario Niño Jesús, 28009 Madrid, Spain.; Instituto de Investigación La Princesa, 28009 Madrid, Spain.; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain.; IMDEA Food Institute, CEIUAM+CSIC, 28049 Madrid, Spain., Brito VN; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, 05403-900 São Paulo, Brasil., Latronico AC; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, 05403-900 São Paulo, Brasil.

المصدر: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2023 Jun 16; Vol. 108 (7), pp. 1758-1767.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375362 Publication Model: Print Cited Medium: Internet ISSN: 1945-7197 (Electronic) Linking ISSN: 0021972X NLM ISO Abbreviation: J Clin Endocrinol Metab Subsets: MEDLINE

مواضيع طبية MeSH: Puberty, Precocious*/drug therapy , Puberty, Precocious*/epidemiology , Puberty, Precocious*/genetics, Male ; Child ; Humans ; Retrospective Studies ; Mutation ; Fathers ; Inheritance Patterns ; Ubiquitin-Protein Ligases/genetics ; Puberty

المؤلفون: Brito VN; Discipline of Endocrinology & Metabolism, Department of Internal Medicine, University of Sao Paulo Medical School, University of Sao Paulo, Sao Paulo 01246 903, Brazil., Canton APM; Discipline of Endocrinology & Metabolism, Department of Internal Medicine, University of Sao Paulo Medical School, University of Sao Paulo, Sao Paulo 01246 903, Brazil., Seraphim CE; Discipline of Endocrinology & Metabolism, Department of Internal Medicine, University of Sao Paulo Medical School, University of Sao Paulo, Sao Paulo 01246 903, Brazil., Abreu AP; Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Macedo DB; Discipline of Endocrinology & Metabolism, Department of Internal Medicine, University of Sao Paulo Medical School, University of Sao Paulo, Sao Paulo 01246 903, Brazil.; Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Núcleo de Atenção Médica Integrada, Centro de Ciências da Saúde, Universidade de Fortaleza, Fortaleza 60811 905, Brazil., Mendonca BB; Discipline of Endocrinology & Metabolism, Department of Internal Medicine, University of Sao Paulo Medical School, University of Sao Paulo, Sao Paulo 01246 903, Brazil., Kaiser UB; Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Argente J; Hospital Infantil Universitario Niño Jesús, Department of Endocrinology and Department of Pediatrics, Universidad Autónoma de Madrid, Spanish PUBERE Registry, CIBER of Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos III, IMDEA Institute, Madrid 28009, Spain., Latronico AC; Discipline of Endocrinology & Metabolism, Department of Internal Medicine, University of Sao Paulo Medical School, University of Sao Paulo, Sao Paulo 01246 903, Brazil.

المصدر: Endocrine reviews [Endocr Rev] 2023 Mar 04; Vol. 44 (2), pp. 193-221.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 8006258 Publication Model: Print Cited Medium: Internet ISSN: 1945-7189 (Electronic) Linking ISSN: 0163769X NLM ISO Abbreviation: Endocr Rev Subsets: MEDLINE

مواضيع طبية MeSH: Puberty, Precocious*/diagnosis , Puberty, Precocious*/genetics , Hypothalamic Diseases*/complications, Humans ; Gonadotropin-Releasing Hormone/metabolism ; Hypothalamus ; Puberty ; Ubiquitin-Protein Ligases/metabolism

SCR Disease Name: Hypothalamic hamartomas

المؤلفون: Soriano-Guillén L; Department of Pediatrics, Universidad Autónoma de Madrid, Madrid, Spain.; Department of Pediatrics, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.; Instituto de Investigación Fundación Jiménez Díaz, Madrid, Spain., Tena-Sempere M; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain.; Department of Cell Biology, Physiology and Immunology, University of Cordoba, Córdoba, Spain.; Hospital Universitario Reina Sofía, Córdoba, Spain.; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Córdoba, Spain.; Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine and Turku Center for Disease Modeling, University of Turku, Turku, Finland., Seraphim CE; Laboratory of Hormones and Molecular Genetics, LIM42, Developmental Endocrinology Unit, Department of Internal Medicine, Discipline Endocrinology and Metabolism, Faculty of Medicine, Clinicas Hospital, University of Sao Paulo, Sao Paulo, Brazil., Latronico AC; Laboratory of Hormones and Molecular Genetics, LIM42, Developmental Endocrinology Unit, Department of Internal Medicine, Discipline Endocrinology and Metabolism, Faculty of Medicine, Clinicas Hospital, University of Sao Paulo, Sao Paulo, Brazil., Argente J; Department of Pediatrics, Universidad Autónoma de Madrid, Madrid, Spain.; Department of Pediatrics & Pediatric Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Madrid, Spain.; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain.; IMDEA Food Institute, CEIUAM+CSIC, Madrid, Spain.

المصدر: Journal of neuroendocrinology [J Neuroendocrinol] 2022 Feb; Vol. 34 (2), pp. e12979. Date of Electronic Publication: 2021 Apr 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Wiley & Sons Country of Publication: United States NLM ID: 8913461 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2826 (Electronic) Linking ISSN: 09538194 NLM ISO Abbreviation: J Neuroendocrinol Subsets: MEDLINE

مواضيع طبية MeSH: Puberty, Precocious*/genetics, Female ; Humans ; Kisspeptins/metabolism ; Male ; Melanocortins ; Receptors, Kisspeptin-1/genetics ; Sexual Maturation/physiology ; Ubiquitin-Protein Ligases

المؤلفون: Ramos CO; Unidade de Endocrinologia do Desenvolvimento, Disciplina de Endocrinologia e Metabologia da Faculdade de Medicina da Universidade de São Paulo e Laboratório de Hormônios e Genética Molecular LIM 42 do Hospital das Clínicas, São Paulo-SP, Brasil., Canton APM; Unidade de Endocrinologia do Desenvolvimento, Disciplina de Endocrinologia e Metabologia da Faculdade de Medicina da Universidade de São Paulo e Laboratório de Hormônios e Genética Molecular LIM 42 do Hospital das Clínicas, São Paulo-SP, Brasil., Seraphim CE; Unidade de Endocrinologia do Desenvolvimento, Disciplina de Endocrinologia e Metabologia da Faculdade de Medicina da Universidade de São Paulo e Laboratório de Hormônios e Genética Molecular LIM 42 do Hospital das Clínicas, São Paulo-SP, Brasil., Faria AG; Unidade de Endocrinologia do Desenvolvimento, Disciplina de Endocrinologia e Metabologia da Faculdade de Medicina da Universidade de São Paulo e Laboratório de Hormônios e Genética Molecular LIM 42 do Hospital das Clínicas, São Paulo-SP, Brasil., Tinano FR; Unidade de Endocrinologia do Desenvolvimento, Disciplina de Endocrinologia e Metabologia da Faculdade de Medicina da Universidade de São Paulo e Laboratório de Hormônios e Genética Molecular LIM 42 do Hospital das Clínicas, São Paulo-SP, Brasil., Mendonca BB; Unidade de Endocrinologia do Desenvolvimento, Disciplina de Endocrinologia e Metabologia da Faculdade de Medicina da Universidade de São Paulo e Laboratório de Hormônios e Genética Molecular LIM 42 do Hospital das Clínicas, São Paulo-SP, Brasil., Latronico AC; Unidade de Endocrinologia do Desenvolvimento, Disciplina de Endocrinologia e Metabologia da Faculdade de Medicina da Universidade de São Paulo e Laboratório de Hormônios e Genética Molecular LIM 42 do Hospital das Clínicas, São Paulo-SP, Brasil., Brito VN; Unidade de Endocrinologia do Desenvolvimento, Disciplina de Endocrinologia e Metabologia da Faculdade de Medicina da Universidade de São Paulo e Laboratório de Hormônios e Genética Molecular LIM 42 do Hospital das Clínicas, São Paulo-SP, Brasil.

المصدر: Journal of pediatric endocrinology & metabolism : JPEM [J Pediatr Endocrinol Metab] 2021 Jul 23; Vol. 34 (11), pp. 1371-1377. Date of Electronic Publication: 2021 Jul 23 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Walter de Gruyter Country of Publication: Germany NLM ID: 9508900 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2191-0251 (Electronic) Linking ISSN: 0334018X NLM ISO Abbreviation: J Pediatr Endocrinol Metab Subsets: MEDLINE

مواضيع طبية MeSH: Body Height/*drug effects , Gonadotropin-Releasing Hormone/*analogs & derivatives , Leuprolide/*therapeutic use , Menarche/*drug effects , Puberty, Precocious/*drug therapy , Reproduction/*drug effects, Child ; Female ; Humans ; Leuprolide/administration & dosage ; Puberty, Precocious/mortality ; Retrospective Studies ; Treatment Outcome

المؤلفون: Seraphim CE; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Canton APM; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Montenegro L; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Piovesan MR; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Macedo DB; Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Cunha M; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Guimaraes A; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Ramos CO; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Benedetti AFF; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., de Castro Leal A; Departamento de Saúde Integrada da Universidade do Estado do Pará (UEPA), Santarém, Pará, Brazil., Gagliardi PC; Division of Endocrinology, Diabetes, and Metabolism, Nemours Children's Clinic, Jacksonville, FL, USA., Antonini SR; Department of Pediatrics, Ribeirao Preto Medical School, University of Sao Paulo, Brazil., Gryngarten M; Centro de Investigaciones Endocrinológicas 'Dr. César Bergadá' (Consejo Nacional de Investigaciones Científicas y Técnicas - FEI - División de Endocrinología, Hospital de Niños Ricardo Gutiérrez), Buenos Aires, Argentina., Arcari AJ; Centro de Investigaciones Endocrinológicas 'Dr. César Bergadá' (Consejo Nacional de Investigaciones Científicas y Técnicas - FEI - División de Endocrinología, Hospital de Niños Ricardo Gutiérrez), Buenos Aires, Argentina., Abreu AP; Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Kaiser UB; Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Soriano-Guillén L; Department of Pediatrics, IIS-Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Spanish PUBERE Registry, Madrid, Spain., Escribano-Muñoz A; Endocrinology Unit, Department of Pediatrics, University Hospital Virgen of Arrixaca, Spanish PUBERE Registry, Murcia, Spain., Corripio R; Pediatric Endocrinology Department, Corporació Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí I3PT. Universitat Autònoma de Barcelona. Spanish PUBERE Registry, Sabadell, Spain., Labarta JI; Pediatric Endocrinology Unit, Department of Pediatrics, Hospital Universitario Miguel Servet, Instituto de Investigación Sanitaria de Aragón, Spanish PUBERE Registry, Zaragoza, Spain., Travieso-Suárez L; Hospital Infantil Universitario Niño Jesús, Department of Endocrinology and Department of Pediatrics, Universidad Autónoma de Madrid, Spanish PUBERE Registry, CIBER of Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos III, IMDEA Institute, Madrid, Spain., Ortiz-Cabrera NV; Hospital Infantil Universitario Niño Jesús, Department of Endocrinology and Department of Pediatrics, Universidad Autónoma de Madrid, Spanish PUBERE Registry, CIBER of Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos III, IMDEA Institute, Madrid, Spain., Argente J; Hospital Infantil Universitario Niño Jesús, Department of Endocrinology and Department of Pediatrics, Universidad Autónoma de Madrid, Spanish PUBERE Registry, CIBER of Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos III, IMDEA Institute, Madrid, Spain., Mendonca BB; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Brito VN; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Latronico AC; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular LIM/42, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.

المصدر: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2021 Mar 25; Vol. 106 (4), pp. 1041-1050.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375362 Publication Model: Print Cited Medium: Internet ISSN: 1945-7197 (Electronic) Linking ISSN: 0021972X NLM ISO Abbreviation: J Clin Endocrinol Metab Subsets: MEDLINE

مواضيع طبية MeSH: Puberty, Precocious/*genetics , Ubiquitin-Protein Ligases/*genetics, Case-Control Studies ; Child ; Child, Preschool ; Cohort Studies ; Family ; Female ; Genetic Association Studies ; Humans ; Hypothalamic Diseases/epidemiology ; Hypothalamic Diseases/genetics ; Loss of Function Mutation ; Male ; Mutation, Missense ; Puberty, Precocious/epidemiology

المؤلفون: Montenegro L; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular/LIM42, Hospital das Clínicas, Disciplina de Endocrinologia e Metabologia, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Labarta JI; Pediatric Endocrinology Unit, Department of Pediatrics, Hospital Universitario Miguel Servet, Instituto de Investigación Sanitaria de Aragón, Zaragoza, Spain., Piovesan M; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular/LIM42, Hospital das Clínicas, Disciplina de Endocrinologia e Metabologia, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Canton APM; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular/LIM42, Hospital das Clínicas, Disciplina de Endocrinologia e Metabologia, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Corripio R; Pediatric Endocrinology Department, Corporació Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí I3PT, Universitat Autònoma de Barcelona, Sabadell, Spain., Soriano-Guillén L; Pediatric Endocrinology Unit, Institute of Biomedical Research - Hospital Universitario Fundación Jiménez Díaz, Universidad Autónoma de Madrid. Madrid, Spain., Travieso-Suárez L; Department of Pediatrics, Universidad Autónoma de Madrid. Departments of Pediatrics and Pediatric Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, IMDEA Food Institute. Madrid, Spain., Martín-Rivada Á; Department of Pediatrics, Universidad Autónoma de Madrid. Departments of Pediatrics and Pediatric Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, IMDEA Food Institute. Madrid, Spain., Barrios V; Department of Pediatrics, Universidad Autónoma de Madrid. Departments of Pediatrics and Pediatric Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, IMDEA Food Institute. Madrid, Spain., Seraphim CE; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular/LIM42, Hospital das Clínicas, Disciplina de Endocrinologia e Metabologia, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Brito VN; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular/LIM42, Hospital das Clínicas, Disciplina de Endocrinologia e Metabologia, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Latronico AC; Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular/LIM42, Hospital das Clínicas, Disciplina de Endocrinologia e Metabologia, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Argente J; Department of Pediatrics, Universidad Autónoma de Madrid. Departments of Pediatrics and Pediatric Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, IMDEA Food Institute. Madrid, Spain.

المصدر: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2020 Oct 01; Vol. 105 (10).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375362 Publication Model: Print Cited Medium: Internet ISSN: 1945-7197 (Electronic) Linking ISSN: 0021972X NLM ISO Abbreviation: J Clin Endocrinol Metab Subsets: MEDLINE

مواضيع طبية MeSH: Calcium-Binding Proteins/*genetics , Membrane Proteins/*genetics , Puberty, Precocious/*genetics, Brazil ; Calcium-Binding Proteins/blood ; Child ; DNA Mutational Analysis ; Female ; Humans ; Loss of Function Mutation ; Male ; Membrane Proteins/blood ; Puberty, Precocious/blood ; Puberty, Precocious/diagnosis ; Puberty, Precocious/metabolism ; RNA Splice Sites/genetics ; Ubiquitin-Protein Ligases/genetics