المؤلفون: José Pinto, João R. C. Ramos, Rafael S. Costa, Sergio Rossell, Patrick Dumas, Rui Oliveira

المصدر: Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)

مصطلحات موضوعية: hybrid modeling, deep neural networks, first-principles, ADAM, stochastic regularization, CHO-K1 cells, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fbioe.2023.1237963/full; https://doaj.org/toc/2296-4185

URL الوصول: https://doaj.org/article/f2f3ed691a3c4435b69a016c5e18c1be

المؤلفون: Wout Megchelenbrink, Sergio Rossell, Martijn A Huynen, Richard A Notebaart, Elena Marchiori

المصدر: PLoS ONE, Vol 10, Iss 10, p e0139665 (2015)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4601694?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/c56482c8745e4f95944ed8831ccfd094

المؤلفون: Sergio Rossell, Martijn A Huynen, Richard A Notebaart

المصدر: PLoS Computational Biology, Vol 9, Iss 3, p e1002988 (2013)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3605102?pdf=render; https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/6e993564e45d4c5388da2da21cc4fd9c

المؤلفون: Julien Beyrath, Jan A.M. Smeitink, Charlotte A. Hoogstraten, G. Herma Renkema, Ria de Haas, Tom J.J. Schirris, Sanne J. C. M. Frambach, Peter H.G.M. Willems, Richard A. Notebaart, Frans G. M. Russel, Sergio Rossell, Martijn A. Huynen

المصدر: Biochimica et Biophysica Acta-Molecular Basis of Disease 1867 (2021) 4
Biochimica et Biophysica Acta-Molecular Basis of Disease, 1867(4)
Biochimica et biophysica acta. Molecular basis of disease, 1867, 4
Biochimica et biophysica acta. Molecular basis of disease, 1867

مصطلحات موضوعية: 0301 basic medicine, Male, Metabolic network modeling, medicine.medical_specialty, Enzyme complex, Mitochondrial Diseases, medicine.drug_class, Stimulation, Oxidative phosphorylation, Fibrate, Motor Activity, Levensmiddelenmicrobiologie, Biological pathway, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Oxidoreductase, Internal medicine, medicine, Animals, Humans, NAD(P)H, Molecular Biology, Ndufs4 mice, chemistry.chemical_classification, Electron Transport Complex I, Cholesterol, Fibric Acids, Metabolic Disorders Radboud Institute for Molecular Life Sciences [Radboudumc 6], Complex I deficiency, Fibroblasts, Leigh syndrome, Biosynthetic Pathways, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], chemistry, Food Microbiology, Molecular Medicine, Female, Cholesterol biosynthesis, NAD+ kinase, Oxidation-Reduction, 030217 neurology & neurosurgery, NADP

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f94fa7cc37c361225d6438bfd4d3973
https://research.wur.nl/en/publications/stimulation-of-cholesterol-biosynthesis-in-mitochondrial-complex-

المؤلفون: Alexander Lindenbergh, Hans V. Westerhoff, Sergio Rossell, Barbara M. Bakker, Arthur L. Kruckeberg, Coen C. van der Weijden, Karen van Eunen

المصدر: FEMS Yeast Research. 8:155-164

مصطلحات موضوعية: Regulation of gene expression, Hexokinase, Saccharomyces cerevisiae Proteins, Mutant, Saccharomyces cerevisiae, Glucose transporter, Wild type, General Medicine, Biology, biology.organism_classification, Applied Microbiology and Biotechnology, Microbiology, chemistry.chemical_compound, Glucose, chemistry, Biochemistry, Gene Expression Regulation, Fungal, Fermentation, Glycolysis, Gene Deletion, Phosphofructokinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ddecec351b7fa488f80b4f7d89442c
https://doi.org/10.1111/j.1567-1364.2007.00282.x

المؤلفون: Jack T. Pronk, Barbara M. Bakker, Marco J. L. de Groot, Pascale Daran-Lapujade, Sergio Rossell, Johannes H. de Winde, Hans V. Westerhoff, Monique Slijper, Marijke A. H. Luttik, Albert J. R. Heck, Jean-Marc Daran, Walter M. van Gulik

المساهمون: Molecular Cell Physiology

المصدر: PNAS Proceedings of the National Academy of Sciences, 104 (40), 2007
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 104(40), 15753-15758
Daran-Lapujade, P A L, Rossell Aragort, S L, van Gulik, W M, Luttik, M A, de Groot, M J L, Slijper, M, Heck, A J, Daran, J M, de Winde, J H, Westerhoff, H V, Pronk, J T & Bakker, B M 2007, ' The flux through glycolytic enzymes in Saccharomyces cerevisiae are predominantly regulated at posttranscriptional levels ', Proceedings of the National Academy of Sciences of the United States of America, vol. 104, pp. 15753-15758 . https://doi.org/10.1073/pnas.0707476104
Proceedings of the National Academy of Sciences of the United States of America, 104, 15753-15758. National Acad Sciences

مصطلحات موضوعية: Saccharomyces cerevisiae Proteins, Transcription, Genetic, Saccharomyces cerevisiae, Allosteric regulation, posttranscriptional regulation, Protein degradation, Biology, Gene Expression Regulation, Enzymologic, chemistry.chemical_compound, Open Access, Adenosine Triphosphate, Gene Expression Regulation, Fungal, Gene expression, Protein biosynthesis, Homeostasis, Glycolysis, skin and connective tissue diseases, chemistry.chemical_classification, Multidisciplinary, systems biology, Biological Sciences, Benzoic Acid, biology.organism_classification, Kinetics, Enzyme, chemistry, Biochemistry, regulation analysis, sense organs, SDG 6 - Clean Water and Sanitation, Adenosine triphosphate, gene-expression cascade

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a588a1d78099abf32df16150108f13d
https://hdl.handle.net/1871/20716

المؤلفون: Elena Marchiori, Martijn A. Huynen, Richard A. Notebaart, Wout Megchelenbrink, Sergio Rossell

المساهمون: Megchelenbrink, W., Rossell, S., Huynen, M. A., Notebaart, R. A., Marchiori, E.

المصدر: PLoS One, 10, 10
PLoS ONE
PLoS ONE, 10(10)
PLoS One, 10
PLoS ONE, Vol 10, Iss 10, p e0139665 (2015)
PLoS ONE 10 (2015) 10

مصطلحات موضوعية: lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], lcsh:Medicine, Metabolic network, Biology, Space (mathematics), Models, Biological, Reaction rate, Flux (metallurgy), Adenosine Triphosphate, Sampling (signal processing), Life Science, Growth rate, lcsh:Science, GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries), Molecular Biology, Flexibility (engineering), Multidisciplinary, Bacteria, Ecology, lcsh:R, Data Science, Metabolic Disorders Radboud Institute for Molecular Life Sciences [Radboudumc 6], Adaptation, Physiological, Flux balance analysis, lcsh:Q, Biological system, Research Article

وصف الملف: application/octet-stream; application/pdf; text/html

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e73d7d23f586ebd6f4d9a0136535ef1f
https://hdl.handle.net/2066/147303

المؤلفون: Jildau Bouwman, Frank J. Bruggeman, de J. Haan, Hans V. Westerhoff, Sergio Rossell, Barbara M. Bakker, Hanna M. Härdin, van Karen Eunen

المساهمون: Molecular Cell Physiology, Physics of Living Systems, Scientific Computing

المصدر: IEE Proceedings. Systems Biology, 153(5), 318-322. Institution of Engineering and Technology
IEE Proceedings Systems Biology, 153(5), 318-322
Bruggeman, F J, de Haan, J, Hardin, H M, Bouwman, J G, Rossell Aragort, S L, van Eunen, K, Bakker, B M & Westerhoff, H V 2006, ' Time-dependent hierarchical regulation analysis: deciphering cellular adaptation ', IEE Proceedings. Systems Biology, vol. 153, no. 5, pp. 318-322 . https://doi.org/10.1049/ip-syb:20060027

مصطلحات موضوعية: Feedback inhibition, Single process, Proteome, Cellular adaptation, Metabolic Clearance Rate, Covalent modification, Computational biology, Biology, Models, Biological, Cell Physiological Phenomena, Feedback, Transcription (biology), Genetics, Animals, Humans, Computer Simulation, RNA, Messenger, Molecular Biology, chemistry.chemical_classification, Kinetic model, Cell Biology, Adaptation, Physiological, Kinetics, Enzyme, Gene Expression Regulation, chemistry, Biochemistry, Metabolic enzymes, Modeling and Simulation, Molecular Medicine, Algorithms, Signal Transduction, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4b3cf2e6c045890a6a1ea2045c832e
https://hdl.handle.net/1871.1/2e94b5f7-2f2e-48df-a1e7-bb5c00d61e65

المؤلفون: Christof Francke, Arjen van Tuijl, Alexander Lindenbergh, Barbara M. Bakker, Sergio Rossell, Coen C. van der Weijden, Hans V. Westerhoff

المساهمون: Molecular Cell Physiology

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 103, 2166-2171. National Acad Sciences
Rossell, S, van der Weijden, C C, Lindenbergh, P A, van Tuijl, J H, Francke, C, Bakker, B M & Westerhoff, H V 2006, ' Unraveling the complexity of flux regulation; a new method demonstrated for nutrient starvation in Saccharomyces cerevisiae. ', Proceedings of the National Academy of Sciences of the United States of America, vol. 103, pp. 2166-2171 . https://doi.org/10.1073/pnas.0509831103

مصطلحات موضوعية: chemistry.chemical_classification, Multidisciplinary, biology, Mechanism (biology), ved/biology, Nitrogen, Saccharomyces cerevisiae, ved/biology.organism_classification_rank.species, Biological Transport, Metabolism, Biological Sciences, biology.organism_classification, Carbon, Nutrient starvation, Cell biology, Enzyme, Biochemistry, chemistry, Gene expression, Glycolysis, Model organism

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b1ce063587d6b19ec7533cfc207918
https://hdl.handle.net/1871/20833

المؤلفون: Coen C. van der Weijden, Barbara M. Bakker, Sergio Rossell, Hans V. Westerhoff, Arthur L. Kruckeberg

المصدر: FEMS Yeast Research. 5:611-619

مصطلحات موضوعية: Starvation, biology, Saccharomyces cerevisiae, Glucose transporter, General Medicine, biology.organism_classification, Applied Microbiology and Biotechnology, Microbiology, Isozyme, Yeast, Biochemistry, medicine, medicine.symptom, Flux (metabolism), Functional genomics, Function (biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::66261f986d1633ce78d66395f149cb53
https://doi.org/10.1016/j.femsyr.2004.11.003