المؤلفون: Atefeh Zarepour, Abdurrahim Can Egil, Melike Cokol Cakmak, Monireh Esmaeili Rad, Yuksel Cetin, Seyma Aydinlik, Gozde Ozaydin Ince, Ali Zarrabi

المصدر: Polymers, Vol 15, Iss 2, p 298 (2023)

مصطلحات موضوعية: niosome, Rose Bengal, dual responsive nanocarrier, anticancer, antibacterial, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2073-4360/15/2/298; https://doaj.org/toc/2073-4360

URL الوصول: https://doaj.org/article/389f25ec82a440a0af239f5588270532

المؤلفون: Timucin Avsar, Tuğçe Kan, Serdar Durdagi, Ayşen Güngör, Seyma Aydinlik, YÜKSEL ÇETIN

المصدر: Current Medicinal Chemistry. 29:5925-5948

مصطلحات موضوعية: Pharmacology, Drug Discovery, Organic Chemistry, Molecular Medicine, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c1ce0a18c10755b3690524e332efbf4b
https://doi.org/10.2174/0929867329666220627121416

المؤلفون: Yuksel, Cetin, Seyma, Aydinlik, Aysen, Gungor, Tugce, Kan, Timucin, Avsar, Serdar, Durdagi

المصدر: Current medicinal chemistry. 29(38)

مصطلحات موضوعية: SARS-CoV-2, Cell Culture Techniques, Humans, Ligands, Antiviral Agents, High-Throughput Screening Assays, COVID-19 Drug Treatment

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::d2d7671f7fe19a3710409c8723c5d0e9
https://pubmed.ncbi.nlm.nih.gov/35761502

المؤلفون: Ece Erdemoglu, Nurettin Tokay, Şaban Tekin, Lalehan Oktay, Elif Acar, Hasan DeMirci, Timucin Avsar, Alpsu Olkan, Yesim Yumak, Bertan Koray Balcioglu, Muge Didem Orhan, Seyma Calis, Hasan Umit Ozturk, Sehriban Buyukkilic, Yuksel Cetin, Yasar Enes Butun, Aysenur Ozcan, Atilla Akdemir, Muge Serhatli, Şeyma Işık, Tugba Bagci-Onder, Seyma Aydinlik, Mustafa Guzel, Serdar Durdagi, Alisan Kayabolen, Ilayda Tolu

المساهمون: Kayabölen, Alişan, Önder, Tuğba Bağcı (ORCID 0000-0003-3646-2613 & YÖK ID 184359), Demirci, Hasan (ORCID 0000-0002-9135-5397 & YÖK ID 307350), Durdağı, Serdar, Avşar, Timuçin, Orhan, Müge Didem, Serhatlı, Müge, Balcıoğlu, Bertan Koray, Öztürk, Hasan Ümit, Çetin, Yüksel, Aydınlık, Şeyma, Tekin, Şaban, Güzel, Mustafa, Akdemir, Atilla, Çalış, Şeyma, Oktay, Lalehan, Tolu, İlayda, Bütün, Yaşar Enes, Erdemoğlu, Ece, Olkan, Alpsu, Tokay, Nurettin, Işık, Şeyma, Özcan, Ayşenur, Acar, Elif, Büyükkılıç, Şehriban, Yumak, Yeşim, Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM), School of Medicine, College of Sciences, Department of Molecular Biology and Genetics, AKDEMİR, ATİLLA

المصدر: Molecular Therapy

مصطلحات موضوعية: Cyclopropanes, Models, Molecular, Vitro Studies, pseudovirus neutralization, Protein Conformation, medicine.medical_treatment, Pharmacology, Acetates, Neutralization, Drug Discovery, Chlorocebus aethiops, MD simulations, Leukotriene, drug repurposing, Molecular Structure, Chemistry, Biotechnology and applied microbiology, Serine Endopeptidases, Small molecule, Molecular Docking Simulation, montelukast, virus neutralization, Quinolines, Molecular Medicine, Original Article, Angiotensin-Converting Enzyme 2, medicine.drug, Cell Survival, COVID-19, Drug repurposing, Molecular docking, Montelukast, Pseudovirus Neutralization, Virus neutralization, Sulfides, Virus, Viral entry, Neutralization Tests, Genetics, medicine, Animals, Humans, Molecular Biology, Vero Cells, Protease, SARS-CoV-2, Silico Simulations, Drug Repositioning, molecular docking, Virus Internalization, In vitro, respiratory tract diseases, HEK293 Cells, A549 Cells

وصف الملف: pdf; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7b5bf178ea2423fe4889fd0a1d910a
https://pubmed.ncbi.nlm.nih.gov/34678509

المؤلفون: Seyma Aydinlik, Ebru Gurel-Gurevin, Elif Ilkay Armutak, Hülya Tuba Kıyan, Ayça Üvez, Veysel T. Yilmaz, Engin Ulukaya

المساهمون: İstinye Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Ulukaya, Engin

مصطلحات موضوعية: MAPK/ERK pathway, inorganic chemicals, Programmed cell death, Angiogenesis, Neovascularization, Physiologic, Chick Chorioallantoic Membrane (CAM), Angiogenesis Inhibitors, Apoptosis, Chick Embryo, Biochemistry, Coordination Complexes, medicine, Human Umbilical Vein Endothelial Cells, Autophagy, Animals, Humans, Extracellular Signal-Regulated MAP Kinases, Protein kinase B, Cells, Cultured, Tube formation, Cell growth, Phospholipase C gamma, Palladium Complex, Cell Biology, VEGF Pathway, Reactive Nitrogen Species, Thalidomide, Oxidative Stress, src-Family Kinases, Focal Adhesion Kinase 1, Human Umbilical Vein Endothelial Cells (HUVECs), Cancer research, Cardiology and Cardiovascular Medicine, Proto-Oncogene Proteins c-akt, medicine.drug, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250b5174e47d21296c43366510a4197e
https://hdl.handle.net/20.500.12713/1980

المؤلفون: Yesim Yumak, Ece Erdemoglu, Elif Acar, Aysenur Ozcan, Ilayda Tolu, Muge Didem Orhan, Yuksel Cetin, Alisan Kayabolen, Alpsu Olkan, Şaban Tekin, Şeyma Işık, Hasan DeMirci, Timucin Avsar, Sehriban Buyukkilic, Muge Serhatli, Tugba Bagci-Onder, Bertan Koray Balcioglu, Nurettin Tokay, Yasar Enes Butun, Serdar Durdagi, Atilla Akdemir, Lalehan Oktay, Seyma Calis, Hasan Umit Ozturk, Seyma Aydinlik, Mustafa Guzel

مصطلحات موضوعية: Leukotriene, Chemistry, In silico, medicine, Pharmacology, Favipiravir, Cytotoxicity, Small molecule, In vitro, Montelukast, Neutralization, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8788d857d84e850cdf2d2aa14fde6598
https://doi.org/10.1101/2020.12.26.424423

المؤلفون: Ceyda Icsel, Veysel T. Yilmaz, Seyma Aydinlik, Muhittin Aygun

المصدر: Dalton transactions (Cambridge, England : 2003). 49(25)

مصطلحات موضوعية: Inorganic Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56d2327ff4eeb687852a1d6b5c00008
https://pubmed.ncbi.nlm.nih.gov/32463408

المؤلفون: Seyma Aydinlik, Muhittin Aygün, Veysel T. Yilmaz, Ceyda Icsel

المساهمون: Bursa Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Kimya Bölümü., Bursa Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Biyoloji Bölümü., İçsel, Ceyda, Aydınlık, Şeyma, Yılmaz, Veysel Turan, ABI-2909-2020, AAI-3342-2021, 2-s2.0-85087758658

مصطلحات موضوعية: Cell viability, Protein bcl 2, Pyridines, Coordination complexes, Apoptosis, Manganese, IC50, Targeting mitochondria, 01 natural sciences, Anticancer activity, Saccharin, Chemical structure, Drug Discovery, Antineoplastic agents, 2,6-bis(benzimidazol-2-yl)pyridine, Enzyme activity, Vivtro DNA-binding, Pyridine derivative, Cell proliferation, Saccharin derivative, chemistry.chemical_classification, 0303 health sciences, Structure activity relation, General Medicine, Manganese derivative, Antineoplastic agent, Drug screening, Molecular docking, Dose-response relationship, drug, Cell membrane depolarization, Drug stability, Human, Saccharinate, Double-strand breaks, Article, Tumor cell culture, Metal, 03 medical and health sciences, Drug synthesis, Pyridine, Dose response, Humans, Pharmacology, Cisplatin, 010405 organic chemistry, Pharmacology & pharmacy, Tumor cells, cultured, Copper, 0104 chemical sciences, Drug effect, Human cell, Oxidative stress, Benzimidazoles, 2,6 bis(2 benzimidazolyl)pyridine derivative, Unclassified drug, Enzyme activation, Antiproliferative activity, MCF-7 cell line, Cobalt complex, Cell survival, chemistry.chemical_compound, Nickel complex, Synthesis, Protein expression level, Iron complex, Caspase 7, DNA cleavage, HT-29 cell line, Chemistry, Caspase 3, Copper complex, Cancer-cells, Ligand cu(II) complexes, Plasmid DNA, Double stranded DNA break, Drug screening assays, antitumor, Heavy metal, visual_art, A-549 cell line, visual_art.visual_art_medium, Tumor necrosis factor receptor superfamily member 6, Chemistry, medicinal, Cobalt, Coordination compound, medicine.drug, Drug cytotoxicity, chemistry.chemical_element, Antineoplastic metal complex, MCF-10A cell line, G1 phase cell cycle checkpoint, 2,6-Bis(2-benzimidazolyl)pyridine, medicine, Benzimidazole derivative, DNA binding, Mitochondrion, 030304 developmental biology, Antineoplastic activity, Hydrogen bond, Reactive oxygen species, Cytotoxic activity, Protein Bax, Organic Chemistry, In vitro study, Structure-activity relationship, Complex, Palladium, 2-Phenylpyridine, Cell-cycle, Metals, heavy, Nickel, Ray crystal-structure, Structural-characterization, Molecular structure, Reactive oxygen metabolite, Controlled study, Nuclear chemistry, First row divalent transition metals, Mitochondrial membrane

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f8f485e05165cb7e96f206ba578ff6
http://hdl.handle.net/11452/29620

المؤلفون: Ceyda Icsel, Seyma Aydinlik, Veysel T. Yilmaz, Muhittin Aygün

المساهمون: Bursa Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Kimya Bölümü., İçsel, Ceyda, Yılmaz, Veysel T., L-7238-2018, AAI-3342-2021

مصطلحات موضوعية: Models, Molecular, Lung Neoplasms, Pyridines, Pyridine, Cytotoxic activities, Palladium(II), Cell, Apoptosis, Antiproliferative activity, Spectroscopic method, MCF-7 cell line, Spectroscopic analysis, Crystallography, X-Ray, 01 natural sciences, Vitro DNA-binding, Synthesis, Chemical structure, Coordination Complexes, Annexin, 2,6-bis(benzimidazol-2-yl)pyridine, Pathology, Cytotoxic T cell, Pyridine derivative, Cells, Cultured, chemistry.chemical_classification, Gel electrophoresis, Lung cancer cells, Crystal-structures, Ligands synthesis, Structure activity relation, Molecular Structure, 2 ,6 bis(2 benzimidazolyl)pyridine, Chemistry, inorganic & nuclear, Chemistry, Zinc, medicine.anatomical_structure, Antineoplastic agent, Drug screening, A-549 cell line, MCF-7 Cells, Derivatives, Coordination compound, Human, Cadmium, Cell death, Electrophoresis, Cell Survival, Anti-cancer agents, Breast tumor, Antineoplastic Agents, Breast Neoplasms, 010402 general chemistry, Molecular model, Inorganic Chemistry, Structure-Activity Relationship, Dose response, medicine, Apoptotic cell death, Humans, Zinc compounds, Benzimidazole derivative, Lung tumor, Cell Proliferation, A549 cell, Reactive oxygen species, Cytotoxic activity, Dose-Response Relationship, Drug, Inhibitors, 010405 organic chemistry, Cadmium compounds, Inhibitory activity, DNA, X ray crystallography, Mercury, Complex, Palladium, 2-Phenylpyridine, Biological organs, Molecular biology, 0104 chemical sciences, Antibacterial, Drug effect, Metabolism, chemistry, A549 Cells, Cell culture, Mercury compounds, Benzimidazoles, Drug Screening Assays, Antitumor, Reactive Oxygen Species, Reactive oxygen metabolite

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d055d44a0f8a3c0e6b2845b9ca9093
https://avesis.deu.edu.tr/publication/details/68e2d993-685c-4346-af72-4d2b554cead9/oai

المؤلفون: Seyma Aydinlik, Engin Ulukaya, Ferda Ari, Serap Celikler, Merve Erkisa

المساهمون: ISU, Rektörlük, Uygulama ve Araştırma Merkezleri, Moleküler Kanser Uygulama ve Araştırma Merkezi, Erkisa Genel, Merve, Ulukaya, Engin

المصدر: Anti-cancer agents in medicinal chemistry. 21(10)

مصطلحات موضوعية: Cancer Research, Programmed cell death, Cell Survival, Antineoplastic Agents, Apoptosis, chemistry.chemical_compound, Structure-Activity Relationship, Coordination Complexes, Autophagy, Tumor Cells, Cultured, Cytotoxic T cell, Humans, Propidium iodide, Viability assay, Protein kinase B, Cell Proliferation, Colorectal Cancer, Pharmacology, Palladium (II) Complex, Dose-Response Relationship, Drug, Molecular Structure, Intrinsic apoptosis, ROS, Metal-Based Compounds, chemistry, Cancer research, Molecular Medicine, Drug Screening Assays, Antitumor, Colorectal Neoplasms, Reactive Oxygen Species, Palladium, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0fbe1b7cb8a7fa85e53260581ce703f
https://pubmed.ncbi.nlm.nih.gov/32990544