المؤلفون: Kathryn Packman, Lyubomir Vassilev, David Heimbrook, Christophe Meille, Michael Linn, Rosario Garrido, Violeta Adames, Shahid Tannu, Kenneth Kolinsky, Edmund Lee, Sazzad Hussain, Zoran Filipovic, Christian Tovar, Antje Walz, Kelli Glenn, Brian Higgins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03937509c03c999ff11b402c64c3a3e1
https://doi.org/10.1158/1078-0432.22456187

المؤلفون: Kathryn Packman, Lyubomir Vassilev, David Heimbrook, Christophe Meille, Michael Linn, Rosario Garrido, Violeta Adames, Shahid Tannu, Kenneth Kolinsky, Edmund Lee, Sazzad Hussain, Zoran Filipovic, Christian Tovar, Antje Walz, Kelli Glenn, Brian Higgins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b1e546610afd48a3c935087a456191
https://doi.org/10.1158/1078-0432.c.6523232.v1

المؤلفون: Pancras C. Wong, John Allocco, Shahid Tannu, Xiuying Ma, Melissa Yarde

المصدر: Journal of pharmacological and toxicological methods. 106

مصطلحات موضوعية: Male, medicine.medical_specialty, Heart Ventricles, Drug Evaluation, Preclinical, 030204 cardiovascular system & hematology, Toxicology, 030226 pharmacology & pharmacy, Ventricular Function, Left, BALB/c, 03 medical and health sciences, Mice, 0302 clinical medicine, Enalapril, Internal medicine, Renin–angiotensin system, medicine, Animals, Humans, Myocardial infarction, Aorta, Pharmacology, Heart Failure, Mice, Inbred BALB C, Ejection fraction, biology, Ventricular Remodeling, business.industry, Angiotensin-converting enzyme, Stroke Volume, medicine.disease, Brain natriuretic peptide, biology.organism_classification, Constriction, Mice, Inbred C57BL, Disease Models, Animal, Heart failure, biology.protein, Cardiology, Disease Progression, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1405c0da2edf1514ad7205a8e1b147c
https://pubmed.ncbi.nlm.nih.gov/33096237

المؤلفون: Michael Linn, Sazzad Hussain, Zoran Filipovic, Packman Kathryn E, Christophe Meille, Edmund J.D. Lee, Kenneth Kolinsky, David C. Heimbrook, Antje Walz, Lyubomir T. Vassilev, Brian Higgins, Rosario Garrido, Violeta Adames, Kelli Glenn, Christian Tovar, Shahid Tannu

المصدر: Clinical Cancer Research. 20:3742-3752

مصطلحات موضوعية: Drug, Cancer Research, Pyrrolidines, media_common.quotation_subject, Administration, Oral, Mice, Nude, Antineoplastic Agents, Apoptosis, Bone Neoplasms, Pharmacology, Drug Administration Schedule, Pharmacokinetics, Cell Line, Tumor, para-Aminobenzoates, Animals, Humans, Potency, Medicine, Dosing, Imidazolines, media_common, Osteosarcoma, biology, business.industry, Antagonist, Proto-Oncogene Proteins c-mdm2, Xenograft Model Antitumor Assays, Cancer treatment, Oncology, Tolerability, biology.protein, Mdm2, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26acc8e595553533cbc45a5f24324fb
https://doi.org/10.1158/1078-0432.ccr-14-0460

المؤلفون: Shaoqing Chen, Paul Gillespie, Sung-Sau So, Steven Gregory Mischke, David Robert Bolin, Nam T. Le, Frank Mennona, Mushtaq Ahmad, Karin Conde-Knape, Charles Burghardt, Hong Wang, Shahid Tannu, Yimin Qian, Jarema Peter Kochan

المصدر: Bioorganic & Medicinal Chemistry Letters. 21:6264-6269

مصطلحات موضوعية: Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing), chemistry.chemical_classification, Ketone, biology, High-throughput screening, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Fructose 6-phosphate, Isoquinolines, Biochemistry, Glutamine, Inhibitory Concentration 50, chemistry.chemical_compound, chemistry, Pharmacokinetics, Enzyme inhibitor, Drug Discovery, biology.protein, Molecular Medicine, Potency, Enzyme Inhibitors, Molecular Biology, Glutamine amidotransferase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ce41d6fc54e9d94c3232db8c5a857f
https://doi.org/10.1016/j.bmcl.2011.09.009

المؤلفون: Jie Pan, Xiuying Ma, Shahid Tannu, Pancras C. Wong, John Allocco

المصدر: Journal of Cardiac Failure. 24:S27

مصطلحات موضوعية: medicine.medical_specialty, Valsartan, business.industry, Internal medicine, Heart failure, Cardiology, Antagonist, Medicine, Cardiology and Cardiovascular Medicine, business, medicine.disease, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f4ab29dd23240d48429df3e47815444f
https://doi.org/10.1016/j.cardfail.2018.07.078

المؤلفون: J Paciorek, Bolin, Jessica D. Ventre, P Gardiner, D Lavelle, L Calzetta, Shahid Tannu, Alexandra Hicks, Nadine Tare, Maureen Hargaden, A Morschauser, Laura Singer, Ta Lin, ID Knowles, M Cazzola, H Michel, Maria Gabriella Matera, Louis M. Renzetti

المصدر: British Journal of Pharmacology. 161:1329-1342

مصطلحات موضوعية: Pharmacology, Agonist, medicine.medical_specialty, business.industry, medicine.drug_class, Vasoactive intestinal peptide, Inflammation, Biological activity, Peptide hormone, Endocrinology, Internal medicine, Medicine, Inverse agonist, medicine.symptom, business, Receptor, Endogenous agonist

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8c952eb6f6347bd34e1f060d95271ebc
https://doi.org/10.1111/j.1476-5381.2010.00975.x

المؤلفون: Tina Molinaro, Robert Alan Goodnow, Louis M. Renzetti, Alexandra Hicks, Satish Choudhry, Xin Wei, Gesine J. Hermann, Qi Qiao, Anjula Pamidimukkala, A. Robert Catala, Maureen Hargaden, Jian Ping Lou, Nadine Tare, John O’Neil, Ueli Gubler, Karen Pozzani, David J Moore, Jennifer Santiago, Ruben Marcano, Paul Gillespie, Rachid Hamid, Noal Cohen, Hyesun Oh, Lisa C. F. Chao, Laura Singer, Jefferson Wright Tilley, Romyr Dominique, Grazyna Kurylko, Ying L. Li, Radhika Venkat, Achyutharao Sidduri, Matthew Blake Wright, Ann F. Hoffman, Shahid Tannu, Gary Cavallo, Nader Fotouhi, Thomas Egan, Martin Lamb, Jessica D. Ventre, Agnieszka Kowalczyk, D Lavelle, Helena Mancebo

المصدر: Journal of Medicinal Chemistry. 53:3502-3516

مصطلحات موضوعية: Primates, Leukotriene B4, medicine.drug_class, Guinea Pigs, Drug Evaluation, Preclinical, Receptors, Leukotriene B4, HL-60 Cells, Pharmacology, Receptors, G-Protein-Coupled, Guinea pig, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Animals, Humans, Receptor, ADME, Chemistry, Phenyl Ethers, Leukotriene B4 receptor, Receptor antagonist, In vitro, Rats, Bioavailability, Biochemistry, Leukotriene Antagonists, Molecular Medicine, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f954d2982302b35c7516d54421fb833
https://doi.org/10.1021/jm1001919

المؤلفون: Cheryl Janson, Martin Weisel, Barry Goggin, Liang Weiling, Adrian J. Fretland, Robert Francis Kester, Christine Lukacs, Edmund Lee, Jennifer Lo, J. Heather Hogg, Xiaochun Han, Kyoungja Hong, Stacy Remiszewski, Shirley Li, Ann Polonskaia, John Anthony Moliterni, Kang Le, Lin Gao, Nam T. Le, Christophe Michoud, A. Schutt, Shahid Tannu, Andrew F. Donnell, Shaoqing Chen, Louis J. Lombardo, Steven Gregory Mischke, Mark T. Dvorozniak, Yan Lou, Christine Tardell, Kenneth Carey Rupert, Doug Aguilar, Dave S. Solis

المصدر: Journal of medicinal chemistry. 56(20)

مصطلحات موضوعية: Models, Molecular, Cell Survival, Ubiquitin-Protein Ligases, Blotting, Western, Mice, Nude, Apoptosis, X-Linked Inhibitor of Apoptosis Protein, Inhibitor of apoptosis, Crystallography, X-Ray, Inhibitor of Apoptosis Proteins, Mice, Heterocyclic Compounds, Cell Line, Tumor, Drug Discovery, Animals, Humans, Caspase, Caspase-9, Caspase 7, Benzodiazepinones, Alanine, biology, Molecular Structure, Chemistry, Caspase 3, Xenograft Model Antitumor Assays, In vitro, Cell biology, XIAP, Protein Structure, Tertiary, Models, Chemical, Cell culture, Cancer cell, biology.protein, Molecular Medicine, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54996c22c1d8fb8749b427ec42349aeb
https://pubmed.ncbi.nlm.nih.gov/24093940

المؤلفون: Xiuying Ma, John Allocco, Pancras C. Wong, Earl J. Crain, William A. Schumacher, Shahid Tannu, Dike Qiu, Patricia L. Smith, Xue-Qing Chen, Brian J. Arey, Jeffrey S. Bostwick, Marisa Flaim

المصدر: Journal of Cardiac Failure. 22:S37

مصطلحات موضوعية: Biased ligand, medicine.medical_specialty, business.industry, Antagonist, medicine.disease, Post myocardial infarction, Heart failure, Internal medicine, ACE inhibitor, Cardiology, Medicine, Cardiology and Cardiovascular Medicine, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9a9388fbdc9f728709885a2b4de0ccd0
https://doi.org/10.1016/j.cardfail.2016.06.115