-
1دورية أكاديمية
المؤلفون: Doris Zane, Shane Roller, Josephine Shelton, Roshni Singh, Rachna Jain, Yan Wang, Bing Yang, Melanie Felx, Thomas Alessi, Paul L. Feldman
المصدر: Microbiology Spectrum, Vol 9, Iss 1 (2021)
مصطلحات موضوعية: tenofovir alafenamide, subcutaneous, human immunodeficiency virus, antiretroviral, preexposure prophylaxis, Microbiology, QR1-502
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2165-0497
-
2
المؤلفون: Zach R. Demkovich, Manjula Gunawardana, Ronald S. Veazey, Ariane van der Straten, Paul L. Feldman, John A. Moss, Ivana Massud, Alessandro Grattoni, Duy Khiet Ho, Frank DIana, Doris Zane, Mark Milad, Fernanda P. Pons-Faudoa, Marc M. Baum, Shane Roller, Thomas J. Hope, Joseph Romano, Charles Dobard, Selvi Srinivasan, J. Gerardo García-Lerma
المصدر: AIDS Research and Human Retroviruses
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Adolescent, Anti-HIV Agents, Immunology, Human immunodeficiency virus (HIV), MEDLINE, HIV Infections, Review Article, medicine.disease_cause, Tenofovir alafenamide, 03 medical and health sciences, 0302 clinical medicine, Virology, medicine, Animals, Humans, Infection control, 030212 general & internal medicine, Tenofovir, Intensive care medicine, Alanine, business.industry, Adenine, virus diseases, Foundation (evidence), long-acting, 030104 developmental biology, Infectious Diseases, Long acting, TAF, New product development, HIV PrEP, Female, Pre-Exposure Prophylaxis, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1960ae602db1d3b15e8c97bb2bac13c
https://doi.org/10.1089/aid.2021.0028 -
3
المؤلفون: Robert Hauptschein, Simon Woodcock, Andrew Belfield, Helen Mason, Dorottya Keppel, Svetlana Markova, Kyuri Kim, Shane Roller, Caroline Phillips, Clifford D. Jones, Robin C. Humphreys
المصدر: Cancer Research. 82:2677-2677
مصطلحات موضوعية: Cancer Research, Oncology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::684a9473fd0244d8741e4264dbb92246
https://doi.org/10.1158/1538-7445.am2022-2677 -
4
المؤلفون: Lindsey T. Harston, David J. Cowan, Shane Roller, Caroline J. Diaz, Thomas J. Rimele, Channa K Jayawickreme, Paul Kenneth Spearing, Grace Chen, Claudia Generaux, Steven M. Sparks
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:4673-4677
مصطلحات موضوعية: 0301 basic medicine, Agonist, Cell Membrane Permeability, Pyrrolidines, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Nutrient sensing, Biochemistry, Madin Darby Canine Kidney Cells, Structure-Activity Relationship, 03 medical and health sciences, Dogs, 0302 clinical medicine, Diabetes mellitus, Drug Discovery, medicine, Animals, Humans, Receptor, Molecular Biology, chemistry.chemical_classification, Chemistry, Organic Chemistry, medicine.disease, Amino acid, Gastrointestinal Tract, HEK293 Cells, 030104 developmental biology, 030220 oncology & carcinogenesis, Molecular Medicine, Calcium, Calcium-sensing receptor, Receptors, Calcium-Sensing
-
5
المؤلفون: Mary K. Grizzle, Ved Srivastava, Rebecca J. Hodge, Mark A. Paulik, Andrew A. Young, Paul L. Feldman, Tom Tlusty, Shane Roller, Sharon Weng, Marci Copeland, William Blackwell, James M. Way, Doris Zane
المصدر: Diabetes. 67
مصطلحات موضوعية: Agonist, medicine.medical_specialty, medicine.drug_class, business.industry, Cholesterol, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Zdf rats, Highly selective, medicine.disease, Obesity, Glucagon, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, chemistry, Internal medicine, Internal Medicine, medicine, business, Glucagon receptor, Exenatide, 030217 neurology & neurosurgery, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5098fe4d71a1e3811239311092ffbb43
https://doi.org/10.2337/db18-1998-p -
6
المؤلفون: Josephine Shelton, William Blackwell, Rebecca J. Hodge, Paul L. Feldman, Doris Zane, James M. Way, Roshni Singh, Ved Srivastava, Shane Roller, Mark A. Paulik, Thomas R. Alessi
المصدر: Diabetes. 67
مصطلحات موضوعية: medicine.medical_specialty, medicine.diagnostic_test, Clinical pathology, business.industry, Endocrinology, Diabetes and Metabolism, Physiology, 030209 endocrinology & metabolism, Hematocrit, Glucagon, 03 medical and health sciences, 0302 clinical medicine, Tolerability, Toxicity, Internal Medicine, medicine, Hemoglobin, Adverse effect, business, Glucagon receptor, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6a8b76a7b392206799084f0d3850bf4e
https://doi.org/10.2337/db18-1997-p -
7
المؤلفون: Erin Swiger, Thomas J. Rimele, Vincent Rash, David Moncol, Donald L. Hertzog, Caroline J. Diaz, Jon L. Collins, Christopher Nystrom, Pierette Banker, David J. Cowan, Channa K Jayawickreme, Josephine Yuen, Sean Ross, Shane Roller, Xi Liang, Steven M. Sparks, Christopher Joseph Aquino, Dock Steven Thomas, Grace Chen
المصدر: Bioorganicmedicinal chemistry letters. 27(5)
مصطلحات موضوعية: 0301 basic medicine, Agonist, Blood Glucose, Male, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Nutrient sensing, Phenylpropanoic acid, Biochemistry, Receptors, G-Protein-Coupled, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, In vivo, Free fatty acid receptor 1, Drug Discovery, medicine, Animals, Humans, Receptor, Molecular Biology, Phenylpropionates, Chemistry, Organic Chemistry, GPR120, medicine.disease, Rats, Disease Models, Animal, 030104 developmental biology, Diabetes Mellitus, Type 2, Molecular Medicine, Metabolic syndrome, Protein Binding
-
8
المؤلفون: Eric E. Boros, Robert L. Dobbins, Maggie S. McIntyre, Ryan Klein, David J. Cowan, Xi Liang, Xiaozhou Yao, Andrew A. Young, Kristin M. Patterson, Paul L. Feldman, John Ray, Christine L. Merrill, Lindsey T. Harston, Jeff L. Ambroso, Jon L. Collins, Shane Roller, Michael J. Bishop, Judith S. Prescott, Christopher Joseph Aquino, Alan Cunningham, Don L. Anderson, Istvan Kaldor, Wu Yulin, Lihong Chen, Josephine Yuen
المصدر: Journal of Medicinal Chemistry. 56:5094-5114
مصطلحات موضوعية: Male, Thiazepines, Portal vein, Hepatic cholesterol, Organic Anion Transporters, Sodium-Dependent, Type 2 diabetes, Pharmacology, Bile Acids and Salts, Methylamines, Mice, Dogs, Animal model, Drug Stability, Clinical investigation, Drug Discovery, medicine, Animals, Humans, Hypoglycemic Agents, Bile acid transporter, Symporters, Chemistry, Apical sodium-dependent bile acid transporter, Metabolism, medicine.disease, Rats, HEK293 Cells, Diabetes Mellitus, Type 2, Solubility, Molecular Medicine
-
9
المؤلفون: Anthony W. Shaw, Theresa M. Williams, Joseph P. Vacca, Scott D. Mosser, Sean Yu, Christopher A. Salvatore, Craig M. Potteiger, Stefanie A. Kane, Diem N. Nguyen, Christopher S. Burgey, James Z. Deng, Shane Roller, Daniel V. Paone, Harold G. Selnick
المصدر: Bioorganic & Medicinal Chemistry Letters. 21:2683-2686
مصطلحات موضوعية: Migraine Disorders, Clinical Biochemistry, hERG, Biological Availability, Pharmaceutical Science, Calcitonin gene-related peptide, Pharmacology, Biochemistry, Inhibitory Concentration 50, Structure-Activity Relationship, Dogs, Calcitonin Gene-Related Peptide Receptor Antagonists, Oral administration, Drug Discovery, Animals, Caprolactam, Humans, Potency, Structure–activity relationship, Molecular Biology, Cells, Cultured, Telcagepant, Molecular Structure, biology, Chemistry, Organic Chemistry, Imidazoles, Antagonist, Azepines, Analgesics, Non-Narcotic, Macaca mulatta, In vitro, Rats, biology.protein, Molecular Medicine
-
10
المؤلفون: Scott D. Mosser, Joseph P. Vacca, Eric L. Moore, Rodney A. Bednar, Shane Roller, John F. Fay, Kathy M. Schirripa, Harold G. Selnick, Michael R. Wood, June J. Kim, Joseph G. Bruno, Christopher A. Salvatore
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:6827-6830
مصطلحات موضوعية: Stereochemistry, Organic Chemistry, Clinical Biochemistry, Quinoline, Antagonist, Pharmaceutical Science, Stereoisomerism, Calcitonin gene-related peptide, Amides, Biochemistry, Combinatorial chemistry, chemistry.chemical_compound, chemistry, Calcitonin Gene-Related Peptide Receptor Antagonists, Amide, Drug Discovery, Molecular Medicine, Chirality (chemistry), Molecular Biology, CGRP receptor, Binding affinities