نتائج البحث - "Shannon McLaughlan"

1

دورية أكاديمية

Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation.

المؤلفون: Victoria E B Hipolito, Jacqueline A Diaz, Kristofferson V Tandoc, Christian Oertlin, Johannes Ristau, Neha Chauhan, Amra Saric, Shannon Mclaughlan, Ola Larsson, Ivan Topisirovic, Roberto J Botelho

المصدر: PLoS Biology, Vol 17, Iss 12, p e3000535 (2019)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

URL الوصول: https://doaj.org/article/f9af41199bcf4e5b85ff1f3c2ec9827e

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2

دورية أكاديمية

mTORC1 and CK2 coordinate ternary and eIF4F complex assembly

المؤلفون: Valentina Gandin, Laia Masvidal, Marie Cargnello, Laszlo Gyenis, Shannon McLaughlan, Yutian Cai, Clara Tenkerian, Masahiro Morita, Preetika Balanathan, Olivier Jean-Jean, Vuk Stambolic, Matthias Trost, Luc Furic, Louise Larose, Antonis E. Koromilas, Katsura Asano, David Litchfield, Ola Larsson, Ivan Topisirovic

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/3b23e374915e42abafd814b872f5dd1d

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3

دورية أكاديمية

Polysome Fractionation and Analysis of Mammalian Translatomes on a Genome-wide Scale

المؤلفون: Valentina Gandin, author¹, Kristina Sikström, author², Tommy Alain, author³, Masahiro Morita, author³, Shannon McLaughlan, author¹, Ola Larsson, author², Ivan Topisirovic, author¹

المصدر: Journal of Visualized Experiments. (87)

الإتاحة: http://www.jove.com/video/51455

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Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth

المصدر: Nature Chemical Biology. 17:1209-1209

مصطلحات موضوعية: Cell Biology, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::87895925246afc37728a83e10bf0992b
https://doi.org/10.1038/s41589-021-00905-4

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5

Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth

المصدر: Nature Chemical Biology. 17:925-925

مصطلحات موضوعية: Cell signaling, Kinase, business.industry, Cancer research, Cancer therapy, Medicine, Tumor growth, Cell Biology, mTORC1, business, Molecular Biology, Small molecule

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0415a59994600e573fae1074c32dc8f6
https://doi.org/10.1038/s41589-021-00843-1

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6

Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation

المؤلفون: Roberto J. Botelho, Neha Chauhan, Johannes Ristau, Christian Oertlin, Amra Saric, Shannon McLaughlan, Ivan Topisirovic, Jacqueline A. Diaz, Kristofferson Tandoc, Victoria E. B. Hipolito, Ola Larsson

المصدر: PLoS Biology
PLoS Biology, Vol 17, Iss 12, p e3000535 (2019)

مصطلحات موضوعية: 0301 basic medicine, Lipopolysaccharides, Phagocyte, Gene Expression, mTORC1, Biochemistry, White Blood Cells, Mice, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Animal Cells, Medicine and Health Sciences, Biology (General), Phagocytes, Innate Immune System, Antigen Presentation, Mice, Inbred C3H, 0303 health sciences, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Chemistry, General Neuroscience, Messenger RNA, TOR Serine-Threonine Kinases, Cell biology, Nucleic acids, medicine.anatomical_structure, Female, Cellular Types, Cellular Structures and Organelles, General Agricultural and Biological Sciences, Research Article, Signal Transduction, QH301-705.5, Endosome, Immune Cells, Phagocytosis, Immunology, Antigen presentation, Antigen-Presenting Cells, Endosomes, Biology, Mechanistic Target of Rapamycin Complex 1, Endocytosis, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Lysosome, Organelle, Genetics, Autophagy, medicine, Animals, PI3K/AKT/mTOR pathway, 030304 developmental biology, Blood Cells, General Immunology and Microbiology, Macrophages, Biology and Life Sciences, Proteins, Cell Biology, Dendritic Cells, Macrophage Activation, Mice, Inbred C57BL, 030104 developmental biology, RAW 264.7 Cells, Immune System, Polyribosomes, RNA, TFEB, Protein Translation, Lysosomes, Ribosomes, Proto-Oncogene Proteins c-akt, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77173a85b4c90fdd6ac592292b5006f8
https://doi.org/10.1101/260257

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Translational and HIF11-Dependent Metabolic Reprograming Underpin Oncometabolome Plasticity and Synergy Between Oncogenic Kinase Inhibitors and Biguanides

المؤلفون: Josie Ursini-Siegel, Celia M. T. Greenwood, Ivan Topisitrovic, Michael Pollak, Gaëlle Bridon, Marie Cargnello, Tiago Ferreira, Daina Avizonis, Young Kyuen Im, Oro Uchenunu, Ola Larsson, Masahiro Morita, Simon-Pierre Gravel, Laura Hulea, Michael Ohh, Shannon McLaughlan, Julie St-Pierre

المصدر: SSRN Electronic Journal.

مصطلحات موضوعية: Serine, Kinase, Biguanide, medicine.drug_class, Chemistry, Cancer cell, Cancer research, medicine, Cancer, Glycolysis, mTORC1, Asparagine, medicine.disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b10f0a5c0e3b272260db8726c1967750
https://doi.org/10.2139/ssrn.3155732

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Translational and HIF1α-dependent metabolic reprograming underpin oncometabolome plasticity and synergy between oncogenic kinase inhibitors and biguanides

المؤلفون: Tiago Ferreira, Oro Uchenunu, Laura Hulea, Josie Ursini-Siegel, Michael Ohh, Celia M. T. Greenwood, Michael Pollak, Shannon McLaughlan, Gaëlle Bridon, Marie Cargnello, Daina Avizonis, Simon-Pierre Gravel, Ola Larsson, Masahiro Morita, Ivan Topisirovic, Young Kyuen Im, Julie St-Pierre

مصطلحات موضوعية: 0303 health sciences, Biguanide, medicine.drug_class, Kinase, mTORC1, Biology, 3. Good health, Serine, 03 medical and health sciences, 0302 clinical medicine, Biochemistry, 030220 oncology & carcinogenesis, Cancer cell, medicine, Cancer research, Glycolysis, Phosphoglycerate dehydrogenase, Asparagine, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7faaa9b924f7b6c53b4a1182c1bc5adb
https://doi.org/10.1101/160879

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mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation

المؤلفون: Valérie Chénard, Chadi Zakaria, Tommy Alain, Ola Larsson, Simon-Pierre Gravel, Meztli Arguello, Masahiro Morita, Julie St-Pierre, Daina Avizonis, Liang Zheng, Eyal Gottlieb, Yann Nouët, Shannon McLaughlan, Valentina Gandin, Arnim Pause, Nahum Sonenberg, Ivan Topisirovic, Michael Pollak, Kristina Sikström

المصدر: Cell Metabolism. 18(5):698-711

مصطلحات موضوعية: Mitochondrial Turnover, Physiology, Cell Respiration, Cell Cycle Proteins, mTORC1, Mechanistic Target of Rapamycin Complex 2, Biology, Mechanistic Target of Rapamycin Complex 1, DNA, Mitochondrial, Models, Biological, Mitochondrial Proteins, 03 medical and health sciences, Mice, 0302 clinical medicine, Adenosine Triphosphate, Translational regulation, Protein biosynthesis, Autophagy, Animals, Humans, RNA, Messenger, Eukaryotic Initiation Factors, Molecular Biology, 030304 developmental biology, Adaptor Proteins, Signal Transducing, Cell Nucleus, 0303 health sciences, Genome, Human, Ribosomal Protein S6 Kinases, TOR Serine-Threonine Kinases, EIF4E, Translation (biology), Cell Biology, Hypoxia-Inducible Factor 1, alpha Subunit, Phosphoproteins, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Cell biology, Mitochondria, DNA-Binding Proteins, Biochemistry, Gene Expression Regulation, 030220 oncology & carcinogenesis, Multiprotein Complexes, Protein Biosynthesis, Energy source, Biogenesis, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79ab99d578f1b1f40d82d533767f993

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10

Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides

المصدر: Cell Metab

مصطلحات موضوعية: 0301 basic medicine, Physiology, medicine.drug_class, Biguanides, Mice, Nude, Cell Cycle Proteins, mTORC1, Mechanistic Target of Rapamycin Complex 1, Article, Serine, Mice, 03 medical and health sciences, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Humans, RNA, Messenger, Asparagine, Amino Acids, Eukaryotic Initiation Factors, Protein Kinase Inhibitors, Molecular Biology, Adaptor Proteins, Signal Transducing, Biguanide, Chemistry, Kinase, Cancer, Cell Biology, Metabolism, HCT116 Cells, Hypoxia-Inducible Factor 1, alpha Subunit, Phosphoproteins, medicine.disease, Xenograft Model Antitumor Assays, 3. Good health, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Drug Resistance, Neoplasm, Cancer cell, Cancer research, K562 Cells, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ca18fca50caa6b56e55d256072ac79
https://doi.org/10.1016/j.cmet.2018.09.001

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