المؤلفون: Liu C; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR 999078, China., Shao NY; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR 999078, China.; MoE Frontiers Science Center for Precision Oncology, University of Macau, Taipa, Macau SAR 999078, China.; Zhuhai UM Science and Technology Research Institute, Zhuhai 519000, China.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 13; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Myocytes, Cardiac*/metabolism , Endothelial Cells*, Humans ; Animals ; Mice ; Infant ; Cell Differentiation ; Embryo, Mammalian ; Heart Atria/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism

المؤلفون: Nukala SB; Department of Pharmacology & Regenerative Medicine, The University of Illinois College of Medicine, 909 S Wolcott Ave, Chicago, IL 60607, USA., Jousma J; Department of Pharmacology & Regenerative Medicine, The University of Illinois College of Medicine, 909 S Wolcott Ave, Chicago, IL 60607, USA., Yan G; Department of Pharmacology & Regenerative Medicine, The University of Illinois College of Medicine, 909 S Wolcott Ave, Chicago, IL 60607, USA., Han Z; Department of Pharmacology & Regenerative Medicine, The University of Illinois College of Medicine, 909 S Wolcott Ave, Chicago, IL 60607, USA., Kwon Y; Department of Pharmacology & Regenerative Medicine, The University of Illinois College of Medicine, 909 S Wolcott Ave, Chicago, IL 60607, USA., Cho Y; Department of Pharmacology & Regenerative Medicine, The University of Illinois College of Medicine, 909 S Wolcott Ave, Chicago, IL 60607, USA., Liu C; Faculty of Health Sciences, University of Macau, Avenida da Universidade, Taipa, Macau SAR 999078, China., Gagnon K; Division of Biochemistry and Molecular Biology, School of Medicine, Southern Illinois University, 1245 Lincoln Drive Carbondale, IL 62901-4413, USA.; Department of Chemistry and Biochemistry, Southern Illinois University, 1245 Lincoln Drive, Carbondale IL 62901, USA., Pinho S; Department of Pharmacology & Regenerative Medicine, The University of Illinois College of Medicine, 909 S Wolcott Ave, Chicago, IL 60607, USA., Rehman J; Department of Pharmacology & Regenerative Medicine, The University of Illinois College of Medicine, 909 S Wolcott Ave, Chicago, IL 60607, USA.; Division of Cardiology, Department of Medicine, The University of Illinois College of Medicine, 840 S Wood Street, Chicago, IL 60612, USA., Shao NY; Faculty of Health Sciences, University of Macau, Avenida da Universidade, Taipa, Macau SAR 999078, China., Ong SB; Department of Medicine and Therapeutics, Faculty of Medicine, Chinese University of Hong Kong (CUHK), 9/F, Lui Che Woo Clinical Sciences Building, Prince of Wales Hospital, Shatin, N.T., Hong Kong, China.; Centre for Cardiovascular Genomics and Medicine (CCGM), Lui Che Woo Institute of Innovative Medicine, 10/F, Lui Che Woo Clinical Sciences Building, Prince of Wales Hospital, Shatin, N.T., Hong Kong, China.; Hong Kong Hub of Paediatric Excellence (HK HOPE), Hong Kong Children's Hospital (HKCH), 8/F, Tower A,1 Shing Cheong Road, Kowloon Bay, Hong Kong, China.; Kunming Institute of Zoology - The Chinese University of Hong Kong (KIZ-CUHK) Joint Laboratory of Bioresources and Molecular Research of Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China., Lee WH; Department of Basic Medical Sciences, University of Arizona College of Medicine, 425 North 5th Street, Phoenix, AZ 85004, USA., Ong SG; Department of Pharmacology & Regenerative Medicine, The University of Illinois College of Medicine, 909 S Wolcott Ave, Chicago, IL 60607, USA.; Department of Medicine and Therapeutics, Faculty of Medicine, Chinese University of Hong Kong (CUHK), 9/F, Lui Che Woo Clinical Sciences Building, Prince of Wales Hospital, Shatin, N.T., Hong Kong, China.

المصدر: Cardiovascular research [Cardiovasc Res] 2023 Aug 19; Vol. 119 (10), pp. 1997-2013.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245 (Electronic) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE

مواضيع طبية MeSH: RNA, Long Noncoding*/genetics , RNA, Long Noncoding*/metabolism, Humans ; Animals ; Mice ; Glycocalyx/metabolism ; Tyrosine Kinase Inhibitors ; Endothelial Cells/metabolism ; Sunitinib/toxicity ; Sunitinib/metabolism

المؤلفون: Sun J; Department of Mathematics, Faculty of Science and Technology, University of Macau, Taipa, Macau, China., Li Y; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macau, China., Xiao LF; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macau, China., Shao NY; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macau, China.; MoE Frontiers Science Center for Precision Oncology, University of Macau, Taipa, Macau, China., Liu M; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

المصدر: Vaccines [Vaccines (Basel)] 2023 May 22; Vol. 11 (5). Date of Electronic Publication: 2023 May 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101629355 Publication Model: Electronic Cited Medium: Print ISSN: 2076-393X (Print) Linking ISSN: 2076393X NLM ISO Abbreviation: Vaccines (Basel) Subsets: PubMed not MEDLINE

المؤلفون: Liu CW; Department of Basic Medical Sciences, University of Arizona College of Medicine, Phoenix, AZ, USA., Le HHT; Department of Basic Medical Sciences, University of Arizona College of Medicine, Phoenix, AZ, USA., Denaro P; Department of Basic Medical Sciences, University of Arizona College of Medicine, Phoenix, AZ, USA., Dai Z; Translational Cardiovascular Research Center, University of Arizona College of Medicine, Phoenix, AZ, USA.; Department of Internal Medicine, Division of Pulmonary, Critical Care and Sleep, University of Arizona College of Medicine, Phoenix, AZ, USA., Shao NY; Health Sciences, University of Macau, Macau, People's Republic of China., Ong SG; Department of Pharmacology and Regenerative Medicine, University of Illinois College of Medicine, Chicago, IL, USA.; Division of Cardiology, Department of Medicine, University of Illinois College of Medicine, Chicago, IL, USA., Lee WH; Department of Basic Medical Sciences, University of Arizona College of Medicine, Phoenix, AZ, USA.; Translational Cardiovascular Research Center, University of Arizona College of Medicine, Phoenix, AZ, USA.

المصدر: Stem cells (Dayton, Ohio) [Stem Cells] 2023 Apr 25; Vol. 41 (4), pp. 328-340.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9304532 Publication Model: Print Cited Medium: Internet ISSN: 1549-4918 (Electronic) Linking ISSN: 10665099 NLM ISO Abbreviation: Stem Cells Subsets: MEDLINE

مواضيع طبية MeSH: Electronic Nicotine Delivery Systems* , Pulmonary Arterial Hypertension*/metabolism , Induced Pluripotent Stem Cells*/physiology, Humans ; Endothelial Cells/metabolism ; Autophagy

المؤلفون: Wu HX; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou, China.; Research Unit of Precision Diagnosis and Treatment for Gastrointestinal Cancer, Chinese Academy of Medical Sciences, Guangzhou, China., Pan YQ; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou, China.; Research Unit of Precision Diagnosis and Treatment for Gastrointestinal Cancer, Chinese Academy of Medical Sciences, Guangzhou, China., He Y; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou, China.; Research Unit of Precision Diagnosis and Treatment for Gastrointestinal Cancer, Chinese Academy of Medical Sciences, Guangzhou, China., Wang ZX; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou, China.; Research Unit of Precision Diagnosis and Treatment for Gastrointestinal Cancer, Chinese Academy of Medical Sciences, Guangzhou, China., Guan WL; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou, China.; Research Unit of Precision Diagnosis and Treatment for Gastrointestinal Cancer, Chinese Academy of Medical Sciences, Guangzhou, China., Chen YX; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou, China.; Research Unit of Precision Diagnosis and Treatment for Gastrointestinal Cancer, Chinese Academy of Medical Sciences, Guangzhou, China., Yao YC; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou, China.; Research Unit of Precision Diagnosis and Treatment for Gastrointestinal Cancer, Chinese Academy of Medical Sciences, Guangzhou, China., Shao NY; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macau, China.; MoE Frontiers Science Center for Precision Oncology, University of Macau, Taipa, Macau, China., Xu RH; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou, China.; Research Unit of Precision Diagnosis and Treatment for Gastrointestinal Cancer, Chinese Academy of Medical Sciences, Guangzhou, China., Wang F; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou, China.; Research Unit of Precision Diagnosis and Treatment for Gastrointestinal Cancer, Chinese Academy of Medical Sciences, Guangzhou, China.

المصدر: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2023 Mar 20; Vol. 41 (9), pp. 1735-1746. Date of Electronic Publication: 2022 Dec 06.

نوع المنشور: Meta-Analysis; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/drug therapy , Lung Neoplasms*/drug therapy , Esophageal Squamous Cell Carcinoma*/drug therapy , Esophageal Neoplasms*/drug therapy, Humans ; B7-H1 Antigen/metabolism ; Programmed Cell Death 1 Receptor ; Ligands ; Apoptosis ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use

المؤلفون: Yao S; Department of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, Hubei, China.; Hubei Cancer Clinical Study Center, Wuhan, Hubei, China., Zhao L; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macau, Macau SAR, China.; Ministry of Education (MoE) Frontiers Science Center for Precision Oncology, University of Macau, Taipa, Macau, Macau SAR, China., Chen S; Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China., Wang H; Department of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, Hubei, China.; Hubei Cancer Clinical Study Center, Wuhan, Hubei, China., Gao Y; Department of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, Hubei, China.; Hubei Cancer Clinical Study Center, Wuhan, Hubei, China., Shao NY; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macau, Macau SAR, China.; Ministry of Education (MoE) Frontiers Science Center for Precision Oncology, University of Macau, Taipa, Macau, Macau SAR, China., Dai M; Department of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, Hubei, China.; Hubei Cancer Clinical Study Center, Wuhan, Hubei, China., Cai H; Department of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, Hubei, China.; Hubei Cancer Clinical Study Center, Wuhan, Hubei, China.

المصدر: Frontiers in immunology [Front Immunol] 2023 Mar 10; Vol. 14, pp. 1135657. Date of Electronic Publication: 2023 Mar 10 (Print Publication: 2023).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Uterine Cervical Neoplasms*/genetics , Uterine Cervical Neoplasms*/therapy, Humans ; Female ; Immunotherapy ; Prognosis ; Multigene Family ; Cell Proliferation ; Tumor Microenvironment/genetics

المؤلفون: Zhao L; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Macau, China., Li Y; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Macau, China., Yi W; Department of Dermatology, Zhongnan Hospital of Wuhan University, Wuhan, China., Yan K; Institute of Cell and Neurobiology, Charité Medical University, Berlin, Germany., Yang C; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Radhakrishnan S; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Li R; Department of Radiation Oncology, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China., Tan R; Translational Chinese Medicine Key Laboratory of Sichuan Province, Sichuan Institute for Translational Chinese Medicine, Sichuan Academy of Chinese Medicine Sciences, Chengdu, China., Fan G; Department of Urology, Huazhong University of Science and Technology Union Shenzhen Hospital, The 6th Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China., Dai M; Department of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China., Liu M; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Shao NY; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Macau, China.; MoE Frontiers Science Center for Precision Oncology, Faculty of Health Sciences, University of Macau, Macau, China.

المصدر: Journal of medical virology [J Med Virol] 2023 Jan; Vol. 95 (1), pp. e28283.

نوع المنشور: Letter; Comment

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print Cited Medium: Internet ISSN: 1096-9071 (Electronic) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Zhao L; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macau, China., Li Y; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macau, China., Yi W; Department of Dermatology, Zhongnan Hospital of Wuhan University, Wuhan, China., Yan K; Institute of Cell and Neurobiology, Charité Medical University, Berlin, Germany., Yang C; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Radhakrishnan S; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Li R; Department of Radiation Oncology, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China., Tan R; Translational Chinese Medicine Key Laboratory of Sichuan Province, Sichuan Institute for Translational Chinese Medicine, Sichuan Academy of Chinese Medicine Sciences, Chengdu, China., Fan G; Department of Urology, Huazhong University of Science and Technology Union Shenzhen Hospital, The 6th Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China., Dai M; Department of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China., Liu M; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Shao NY; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macau, China.; MoE Frontiers Science Center for Precision Oncology, University of Macau, Taipa, Macau SAR, China.

المصدر: Journal of medical virology [J Med Virol] 2022 Oct; Vol. 94 (10), pp. 4727-4734. Date of Electronic Publication: 2022 Jun 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9071 (Electronic) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19*/complications , Hypertension*/complications , Hypertension*/drug therapy , COVID-19 Drug Treatment*, Angiotensin Receptor Antagonists/therapeutic use ; Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; Antihypertensive Agents/therapeutic use ; Calcium Channel Blockers/therapeutic use ; Computational Biology ; Humans ; Retrospective Studies ; SARS-CoV-2

المؤلفون: Le HHT; Department of Basic Medical Sciences, University of Arizona College of Medicine, 425 N 5th Street, Building ABC1, Rm 426, Phoenix, AZ, 85004-2157, USA., Liu CW; Department of Basic Medical Sciences, University of Arizona College of Medicine, 425 N 5th Street, Building ABC1, Rm 426, Phoenix, AZ, 85004-2157, USA., Denaro P 3rd; Department of Basic Medical Sciences, University of Arizona College of Medicine, 425 N 5th Street, Building ABC1, Rm 426, Phoenix, AZ, 85004-2157, USA., Jousma J; Department of Pharmacology and Regenerative Medicine, University of Illinois College of Medicine, Chicago, IL, 60612, USA., Shao NY; Health Sciences, University of Macau, Macau, China., Rahman I; Department of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA., Lee WH; Department of Basic Medical Sciences, University of Arizona College of Medicine, 425 N 5th Street, Building ABC1, Rm 426, Phoenix, AZ, 85004-2157, USA. whlee@arizona.edu.

المصدر: Stem cell research & therapy [Stem Cell Res Ther] 2021 Dec 04; Vol. 12 (1), pp. 593. Date of Electronic Publication: 2021 Dec 04.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE

مواضيع طبية MeSH: E-Cigarette Vapor*/adverse effects , Electronic Nicotine Delivery Systems* , Induced Pluripotent Stem Cells*/metabolism , RNA, Long Noncoding*/genetics , RNA, Messenger*/genetics, Endothelial Cells/metabolism ; Gene Expression Profiling ; Gene Ontology ; Gene Regulatory Networks ; Humans

المؤلفون: Leng Y; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China., Chen M; Department of Genetics and Genomic Sciences, Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, New York City, New York, USA., Dai M; Department of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China., Wu Y; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China., Lei SQ; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China., Yan K; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Shao NY; Faculty of Health Sciences, University of Macau, Zhuhai, Macau, China., Xia Z; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China., Liu M; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

المصدر: Journal of medical virology [J Med Virol] 2021 Jul; Vol. 93 (7), pp. 4060-4062. Date of Electronic Publication: 2021 Feb 01.

نوع المنشور: Letter; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9071 (Electronic) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Complications*/blood , Glycemic Control*, Blood Glucose/*analysis , COVID-19/*complications , COVID-19/*therapy , Diabetes Mellitus/*therapy , Hyperglycemia/*etiology, Adult ; Aged ; COVID-19/blood ; COVID-19/mortality ; Comorbidity ; Female ; Humans ; Hyperglycemia/therapy ; Male ; Middle Aged ; Retrospective Studies ; Severity of Illness Index ; Treatment Outcome