المؤلفون: Amy L. Palmer, Virginia L. Leykam, Andrew Larkin, Sharon K. Krueger, Ian R. Phillips, Elizabeth A. Shephard, David E. Williams

المصدر: Pharmaceuticals, Vol 5, Iss 11, Pp 1147-1159 (2012)

مصطلحات موضوعية: ethionamide, flavin-containing monooxygenase, Mycobacterium tuberculosis, Medicine, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1424-8247/5/11/1147; https://doaj.org/toc/1424-8247

URL الوصول: https://doaj.org/article/f1dc3703e69245a1835269e4be98fc6d

المؤلفون: Sandra L Uesugi, Graham Bench, William M. Baird, Lisbeth K. Siddens, Sharon K. Krueger, Ted J. Ognibene, Erin P. Madeen, David E. Williams, Jessica M. Hummel, Susan C. Tilton, Tammie J. McQuistan, Kim A. Anderson, Kenneth W. Turteltaub, Jordan N. Smith, Stuart Harris

المصدر: Food and Chemical Toxicology. 115:136-147

مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, animal structures, Polycyclic aromatic hydrocarbon, General Medicine, Absorption (skin), Toxicology, complex mixtures, food.food, Smoked salmon, 03 medical and health sciences, Animal data, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, food, chemistry, Pharmacokinetics, Benzo(a)pyrene, 030220 oncology & carcinogenesis, polycyclic compounds, Pyrene, Food science, Carcinogen, Food Science

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e25872fafc218eeb49307558a759e562
https://doi.org/10.1016/j.fct.2018.03.003

المؤلفون: Lisa M. Bramer, Erin P. Madeen, Hannah You, William M. Baird, Sharon K. Krueger, Frank J. Gonzalez, Emily Ho, Katrina M. Waters, Roderick H. Dashwood, David E. Williams, Christiane V. Löhr, Lisbeth K. Siddens

المصدر: Molecular Carcinogenesis. 56:163-171

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.medical_specialty, Transgene, CYP1B1, Wild type, Cytochrome P450, Biology, medicine.disease_cause, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Endocrinology, 030220 oncology & carcinogenesis, Internal medicine, Genotype, Immunology, Humanized mouse, medicine, biology.protein, Carcinogenesis, Molecular Biology, Carcinogen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ecb8b9a091918101f95363746c9cc73e
https://doi.org/10.1002/mc.22480

المؤلفون: Jessica M, Hummel, Erin P, Madeen, Lisbeth K, Siddens, Sandra L, Uesugi, Tammie, McQuistan, Kim A, Anderson, Kenneth W, Turteltaub, Ted J, Ognibene, Graham, Bench, Sharon K, Krueger, Stuart, Harris, Jordan, Smith, Susan C, Tilton, William M, Baird, David E, Williams

المصدر: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 115

مصطلحات موضوعية: Adult, Male, animal structures, Food Safety, Middle Aged, complex mixtures, Article, Young Adult, Salmon, Fish Products, polycyclic compounds, Benzo(a)pyrene, Carcinogens, Animals, Humans, Female, Carbon Radioisotopes, Cooking, Polycyclic Aromatic Hydrocarbons, Aged

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::e1892ff2bc591e1094c588f5361f753d
https://pubmed.ncbi.nlm.nih.gov/29518434

المؤلفون: Christiane V. Löhr, David E. Williams, William M. Baird, Sharon K. Krueger, Lisbeth K. Siddens, Susan C. Tilton, Katrina M. Waters, Andrew Larkin

المصدر: Toxicological Sciences. 146:135-145

مصطلحات موضوعية: Chrysene, Chemistry, Air pollution, Polyaromatic Hydrocarbons and Carcinogenesis, Environmental exposure, Toxicology, medicine.disease_cause, law.invention, Mice, chemistry.chemical_compound, Creosote, law, Environmental chemistry, Carcinogens, polycyclic compounds, medicine, Animals, Organic chemistry, Pyrene, Bioassay, Polycyclic Aromatic Hydrocarbons, Toxicogenomics, Carcinogen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90878cf20b8b236617804659e472c79f
https://doi.org/10.1093/toxsci/kfv080

المؤلفون: Michael E. Garst, Marilyn C. Henderson, J. Fred Stevens, David E. Williams, Karen M. Kedzie, Wenkui K. Fang, Todd M. Heidelbaugh, Daniel W. Gil, Lisbeth K. Siddens, Phong X. Nguyen, Sharon K. Krueger, Ken Chow

المصدر: Toxicology and Applied Pharmacology. 278:91-99

مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, Insecta, Stereochemistry, Metabolite, Thiourea, Thiones, Flavin-containing monooxygenase, Glutathione, Sulfinic acid, Monooxygenase, Toxicology, Article, Cell Line, Mice, chemistry.chemical_compound, chemistry, Nucleophile, Biochemistry, Oxygenases, Animals, Humans, Sulfenic acid, Oxidation-Reduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ca8e926336cc75bb60f46f51b2e296
https://doi.org/10.1016/j.taap.2014.04.002

المؤلفون: Lisbeth K. Siddens, Marilyn C. Henderson, Sharon K. Krueger, David E. Williams

المصدر: Biochemical Pharmacology. 89:141-147

مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, Oxygenase, Reactive oxygen species, biology, Chemistry, Flavin-containing monooxygenase, Hydrogen Peroxide, Monooxygenase, Biochemistry, Article, Superoxide dismutase, chemistry.chemical_compound, Catalase, Oxygenases, Sf9 Cells, biology.protein, Microsome, Animals, Humans, Hydrogen peroxide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0170a4626ccaa3b2b75273d568b99d87
https://doi.org/10.1016/j.bcp.2014.02.006

المؤلفون: William M. Baird, Katrina M. Waters, Sharon K. Krueger, Andrew Larkin, Susan C. Tilton, David E. Williams, Lisbeth K. Siddens

المصدر: Toxicology and Applied Pharmacology. 267:192-199

مصطلحات موضوعية: Chrysene, Polycyclic aromatic hydrocarbon, Aryl hydrocarbon receptor repressor, Computational biology, Toxicology, Risk Assessment, Article, Mice, chemistry.chemical_compound, Fuzzy Logic, Animals, Organic chemistry, Gene Regulatory Networks, Polycyclic Aromatic Hydrocarbons, Skin, Pharmacology, chemistry.chemical_classification, Microarray analysis techniques, dBc, Fold change, chemistry, Cytochrome P-450 CYP1B1, Pyrene, Female, Aryl Hydrocarbon Hydroxylases, Neural Networks, Computer, DNA microarray

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f836b4d69aab4692847cec3692dcedd8
https://doi.org/10.1016/j.taap.2012.12.011

المؤلفون: Elizabeth A. Shephard, Virginia L. Leykam, Sharon K. Krueger, David E. Williams, Amy L. Palmer, Andrew Larkin, Ian Phillips

المصدر: Pharmaceuticals; Volume 5; Issue 11; Pages: 1147-1159
Pharmaceuticals, Vol 5, Iss 11, Pp 1147-1159 (2012)
Pharmaceuticals

مصطلحات موضوعية: flavin-containing monooxygenase, lcsh:Medicine, lcsh:RS1-441, Pharmaceutical Science, Flavin-containing monooxygenase, Pharmacology, 030226 pharmacology & pharmacy, Article, lcsh:Pharmacy and materia medica, Mycobacterium tuberculosis, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, ethionamide, Drug Discovery, medicine, 030304 developmental biology, 0303 health sciences, biology, business.industry, lcsh:R, Wild type, Prodrug, Monooxygenase, biology.organism_classification, 3. Good health, Multiple drug resistance, Molecular Medicine, Ethionamide, business, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7492949ef7bfa9fdfa6ed9c9ae810dd5
https://doi.org/10.3390/ph5111147

المؤلفون: David H. Phillips, Sharon K. Krueger, Susan C. Tilton, David E. Williams, Christopher A. Bradfield, Volker M. Arlt, Christiane V. Löhr, Cliff Pereira, William M. Baird, Andrew Larkin, Katrina M. Waters, Lisbeth K. Siddens

المصدر: Toxicology and Applied Pharmacology
Siddens, L K, Larkin, A, Krueger, S K, Bradfield, C A, Waters, K M, Tilton, S C, Pereira, C B, Loehr, C V, Arlt, V M, Phillips, D H, Williams, D E & Baird, W M 2012, ' Polycyclic aromatic hydrocarbons as skin carcinogens : Comparison of benzo [a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse ', Toxicology and Applied Pharmacology, vol. 264, no. 3, pp. 377-386 . https://doi.org/10.1016/j.taap.2012.08.014

مصطلحات موضوعية: Chrysene, Skin Neoplasms, Stereochemistry, Protein Array Analysis, Polycyclic aromatic hydrocarbon, Mice, Inbred Strains, 010501 environmental sciences, Toxicology, complex mixtures, 01 natural sciences, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, polycyclic compounds, medicine, Benzo(a)pyrene, Animals, Coal tar, Benzopyrenes, Carcinogen, 030304 developmental biology, 0105 earth and related environmental sciences, Pharmacology, chemistry.chemical_classification, Dibenzo[def,p]chrysene, 0303 health sciences, FVB/N Mouse, Principal Component Analysis, Toxicity, Molecular Structure, dBc, DNA adducts, Molecular biology, Carcinogens, Environmental, 3. Good health, Gene Expression Regulation, Neoplastic, chemistry, 13. Climate action, Carcinogens, Pyrene, Gene expression, Transcriptome, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::721051777f0913f0ce14e37b0b23ad8d