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1دورية أكاديمية
المؤلفون: Stephen Antonysamy, Bradley Condon, Zhanna Druzina, Jeffrey B Bonanno, Tarun Gheyi, Feiyu Zhang, Iain MacEwan, Aiping Zhang, Sheela Ashok, Logan Rodgers, Marijane Russell, John Gately Luz
المصدر: PLoS ONE, Vol 8, Iss 12, p e84147 (2013)
وصف الملف: electronic resource
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المؤلفون: Joseph D. Ho, Michelle C. Vargas, Jing Wang, Junliang Hao, Shane Atwell, James A. Monn, Sheela Ashok, Mark G. Bures, Qi Chen, Jeffery M. Schkeryantz
المصدر: Journal of Medicinal Chemistry. 61:10040-10052
مصطلحات موضوعية: 0301 basic medicine, Agonist, Chemistry, Stereochemistry, medicine.drug_class, Protein domain, Crystal structure, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Drug Discovery, medicine, Molecular Medicine, DCPG, Homology modeling, Binding site, Selectivity, Receptor, 030217 neurology & neurosurgery
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3دورية أكاديمية
لا يتم عرض هذه النتيجة على الضيوف.
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المؤلفون: Qi, Chen, Joseph D, Ho, Sheela, Ashok, Michelle C, Vargas, Jing, Wang, Shane, Atwell, Mark, Bures, Jeffery M, Schkeryantz, James A, Monn, Junliang, Hao
المصدر: Journal of medicinal chemistry. 61(22)
مصطلحات موضوعية: Models, Molecular, Binding Sites, Protein Domains, Drug Design, Glycine, Humans, Ligands, Receptors, Metabotropic Glutamate, Benzoates
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المؤلفون: Mark Edward Rempala, Tom Raub, Carlos Mateos, Sehila Pleite, Josh Clayton, William J. Ehlhardt, Huaxing Pei, Bradley Condon, Stephanie L. Stout, Sheela Ashok, Sandaruwan Geeganage, Mei Lai, Burkholder Timothy P, Deidre Michelle Johns, Yong Wang, Kenneth James Junior Henry, Saravanan Parthasarathy, Zhohai Lu, Oscar de Frutos, Pablo A. García
المصدر: Bioorganicmedicinal chemistry letters. 28(10)
مصطلحات موضوعية: 0301 basic medicine, Clinical Biochemistry, Transplantation, Heterologous, Drug Evaluation, Preclinical, Pharmaceutical Science, Pyrimidinones, Molecular Dynamics Simulation, Crystallography, X-Ray, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, 0302 clinical medicine, In vivo, Cell Line, Tumor, Neoplasms, Drug Discovery, Animals, Humans, Phosphorylation, Molecular Biology, Protein kinase B, Protein Kinase Inhibitors, Trifluoromethyl, Binding Sites, Glycogen Synthase Kinase 3 beta, Aryl, Organic Chemistry, Stereoisomerism, Combinatorial chemistry, Protein Structure, Tertiary, 030104 developmental biology, chemistry, Pyran, 030220 oncology & carcinogenesis, Drug Design, Molecular Medicine, Selectivity, Lead compound, Proto-Oncogene Proteins c-akt
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المؤلفون: Aiping Zhang, Yuewei Qian, Feiyu Zhang, Dagart Allison, Bradley Condon, Xun Zhao, James A. Jamison, Sheela Ashok, Tarun Gheyi, Marijane Russell, John G. Luz, Iain MacEwan
المصدر: Journal of Medicinal Chemistry. 56:963-969
مصطلحات موضوعية: Models, Molecular, SIRT3, Protein Conformation, Stereochemistry, Carbazoles, Crystallography, X-Ray, SIRT2, Cofactor, chemistry.chemical_compound, Sirtuin 1, Catalytic Domain, Drug Discovery, Humans, biology, Nicotinamide, Chemistry, Surface Plasmon Resonance, NAD, Histone Deacetylase Inhibitors, Biochemistry, Acetylation, Sirtuin, biology.protein, Molecular Medicine, Histone deacetylase, NAD+ kinase
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المؤلفون: Zhanna Druzina, Tarun Gheyi, Bradley Condon, Iain MacEwan, Sheela Ashok, Jeffrey B. Bonanno, Logan Rodgers, Stephen Antonysamy, Feiyu Zhang, Aiping Zhang, Marijane Russell, John G. Luz
المصدر: PLoS ONE
PLoS ONE, Vol 8, Iss 12, p e84147 (2013)مصطلحات موضوعية: Models, Molecular, Molecular Sequence Data, lcsh:Medicine, macromolecular substances, Spodoptera, medicine.disease_cause, Crystallography, X-Ray, Gene product, Histone H3, Catalytic Domain, SUZ12, medicine, Sf9 Cells, Animals, Humans, Disease, Enhancer of Zeste Homolog 2 Protein, Amino Acid Sequence, lcsh:Science, Genetics, Mutation, Multidisciplinary, biology, lcsh:R, EZH2, Polycomb Repressive Complex 2, Methylation, Cell biology, biology.protein, lcsh:Q, PRC2, Binding domain, Research Article
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المؤلفون: Sheela Ashok, Nicholas J. Koszewski, John Russell
المصدر: Journal of Bone and Mineral Research. 14:1828-1837
مصطلحات موضوعية: Cell Extracts, Receptors, Retinoic Acid, Recombinant Fusion Proteins, Endocrinology, Diabetes and Metabolism, Response element, DNA Footprinting, Oligonucleotides, Retinoic acid, Parathyroid hormone, Retinoid X receptor, Biology, Response Elements, Transfection, Calcitriol receptor, chemistry.chemical_compound, Gene expression, Animals, Humans, Orthopedics and Sports Medicine, Cholecalciferol, Cell Nucleus, Regulation of gene expression, Drug Synergism, Molecular biology, Rats, VDRE, Retinoid X Receptors, Gene Expression Regulation, chemistry, Parathyroid Hormone, Receptors, Calcitriol, Dimerization, Transcription Factors
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المؤلفون: W. Zhao, Ruth Hogue Angeletti, John Russell, G. Christ, Sheela Ashok
المصدر: Molecular Cell Biology Research Communications. 1:221-226
مصطلحات موضوعية: medicine.medical_specialty, Dose-Response Relationship, Drug, Parathyroid hormone, chemistry.chemical_element, Parathyroid chief cell, Biology, Calcium, Calcium in biology, Parathyroid Glands, chemistry.chemical_compound, Endocrinology, BAPTA, chemistry, Parathyroid Hormone, Internal medicine, medicine, Extracellular, Animals, Parathyroid hormone secretion, Cattle, Receptor, Molecular Biology, Cells, Cultured, Signal Transduction
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المؤلفون: Thomas D’Amico, John Russell, Ruth Hogue Angeletti, Sheela Ashok
المصدر: Journal of Bone and Mineral Research. 13:1232-1237
مصطلحات موضوعية: medicine.medical_specialty, Chemokine, DNA, Complementary, Endocrinology, Diabetes and Metabolism, Parathyroid hormone, Biology, Receptors, Interleukin-8B, Parathyroid Glands, GTP-Binding Proteins, Internal medicine, medicine, Animals, Orthopedics and Sports Medicine, RNA, Messenger, Interleukin 8, Receptor, Cells, Cultured, Interleukin-8, Receptors, Interleukin, Parathyroid chief cell, Immunohistochemistry, Molecular biology, Recombinant Proteins, medicine.anatomical_structure, Endocrinology, Gene Expression Regulation, Parathyroid Hormone, biology.protein, Cattle, Receptors, Chemokine, Parathyroid gland, Calcium-sensing receptor, hormones, hormone substitutes, and hormone antagonists, Homeostasis