المؤلفون: Georgia Charkoftaki, Nicholas J. W. Rattray, Per E. Andrén, Richard M. Caprioli, Steve Castellino, Mark W. Duncan, Richard J. A. Goodwin, Kevin L. Schey, Sheerin K. Shahidi-Latham, Kirill A. Veselkov, Caroline H. Johnson, Vasilis Vasiliou

المصدر: Human Genomics, Vol 12, Iss 1, Pp 1-6 (2018)

مصطلحات موضوعية: Medicine, Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s40246-018-0142-x; https://doaj.org/toc/1479-7364

URL الوصول: https://doaj.org/article/7368424fbc7c49c6acebb5cbffb8b825

المؤلفون: Arun Kashyap, Sami Hussein, Sahar Mazar, Kate Markham, Anthony Mastracci, Ritu Sharma, Sheerin K. Shahidi-Latham, Irene Griswold-Prenner

المصدر: Cancer Research. 83:3941-3941

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b1f33b53c9d714d10860f380e5683f8b
https://doi.org/10.1158/1538-7445.am2023-3941

المؤلفون: Anh Miu, Benjamin D. Sellers, Maria Ruiz-Gonzalez, Jian Payandeh, Peter Liu, L. Martin, Kerry R Buchholz, Dewakar Sangaraju, Guanghui Han, Mark S. Hunter, Elizabeth Skippington, Wendy Sandoval, Emily J. Hanan, Cameron L. Noland, Trisha Dela Vega, Daniel P. DePonte, Erik Verschueren, Danielle L. Swem, Min Xu, Sheerin K. Shahidi-Latham, Nicholas N. Nickerson, Summer Park, Steven T. Rutherford, Nicholas J. Skelton, Qingling Li, Janina Reeder, Kelly M. Storek, Cornelius Gati, Thomas Clairfeuille

المصدر: Nature. 584:479-483

مصطلحات موضوعية: Lipopolysaccharides, Models, Molecular, Lipopolysaccharide, Hydrolases, medicine.drug_class, Polymyxin, Amino Acid Motifs, Microbial Sensitivity Tests, Plasma protein binding, Amidohydrolases, Lipid A, 03 medical and health sciences, chemistry.chemical_compound, Enzyme Stability, Escherichia coli, medicine, Inner membrane, 030304 developmental biology, 0303 health sciences, Binding Sites, Genes, Essential, Microbial Viability, Multidisciplinary, Virulence, 030306 microbiology, Escherichia coli Proteins, Cell Membrane, Periplasmic space, Peptide Fragments, Cell biology, Bacterial Outer Membrane, chemistry, Periplasm, lipids (amino acids, peptides, and proteins), Bacterial outer membrane, Biogenesis, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60f6821b117c57797c53d6a1fae98ab
https://doi.org/10.1038/s41586-020-2597-x

المؤلفون: Jenninfer LeCouter, Xingrong Liu, Cristine Quiason, Jacob Z. Chen, Joe Lubach, Jay Cheng, Eric Solon, Timothy P. Heffron, Thomas H. Lee, Jim Nonomiya, Matthew Wright, Xiaorong Liang, Savita Ubhayakar, Cornelis E. C. A. Hop, Sheerin K. Shahidi-Latham

المصدر: Drug metabolism and disposition: the biological fate of chemicals. 48(5)

مصطلحات موضوعية: Male, genetic structures, Pharmaceutical Science, Angiogenesis Inhibitors, Pharmacology, 030226 pharmacology & pharmacy, Models, Biological, Umbilical vein, Neovascularization, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, In vivo, medicine, Human Umbilical Vein Endothelial Cells, Distribution (pharmacology), Animals, Humans, Tissue Distribution, PI3K/AKT/mTOR pathway, Phosphoinositide-3 Kinase Inhibitors, Phosphoinositide 3-kinase, biology, TOR Serine-Threonine Kinases, Retinal, eye diseases, Choroidal Neovascularization, Rats, Disease Models, Animal, chemistry, Solubility, 030220 oncology & carcinogenesis, Injections, Intravenous, Intravitreal Injections, biology.protein, sense organs, Rabbits, medicine.symptom, Ophthalmic Solutions, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486db2324c0da1f7399ce0d163e7cabf
https://pubmed.ncbi.nlm.nih.gov/32132091

المؤلفون: E. Ellen Jones, Cristine Quiason, Gregory A. Grabowski, Richard R. Drake, Xueheng Zhao, Ying Sun, Stephanie Dale, Wujuan Zhang, Sheerin K. Shahidi-Latham, Kenneth D.R. Setchell

المصدر: SLAS Discovery. 22:1218-1228

مصطلحات موضوعية: 0301 basic medicine, MALDI imaging, Spectrometry, Mass, Electrospray Ionization, Pathology, medicine.medical_specialty, Galactosylceramides, Protein degradation, Biochemistry, Glycosphingolipids, Analytical Chemistry, 03 medical and health sciences, Lactosylceramide, chemistry.chemical_compound, Imaging, Three-Dimensional, 0302 clinical medicine, Tandem Mass Spectrometry, medicine, Animals, music, Prosaposin, Gaucher Disease, music.instrument, Chemistry, Brain, Glycosphingolipid, Molecular biology, Mice, Inbred C57BL, 030104 developmental biology, Organ Specificity, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Molecular Medicine, Immunohistochemistry, lipids (amino acids, peptides, and proteins), Glucosylceramides, 030217 neurology & neurosurgery, Chromatography, Liquid, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146aba075bcce4cfeb156c5a32af539f
https://doi.org/10.1177/2472555217719372

المؤلفون: Susan Wong, Ryan H. Takahashi, Sheerin K. Shahidi-Latham, Jae H. Chang

المصدر: Drug Metabolism and Disposition. 45:581-585

مصطلحات موضوعية: 0301 basic medicine, Population, Pharmaceutical Science, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Isotopes, Cytochrome P-450 CYP3A, medicine, Humans, Drug Interactions, RNA, Messenger, Amino Acids, education, Cells, Cultured, Pharmacology, chemistry.chemical_classification, education.field_of_study, Isotope, biology, Stable isotope ratio, Cytochrome P450, Coculture Techniques, Amino acid, Kinetics, 030104 developmental biology, medicine.anatomical_structure, Biochemistry, chemistry, Isotope Labeling, Hepatocyte, Hepatocytes, biology.protein, Degradation (geology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09f31dcea8e56c5cff14ec9973388fa
https://doi.org/10.1124/dmd.116.074393

المؤلفون: Imke H. Bartelink, Brendan Prideaux, Greg M. Thurber, Zena Wimana, Sheerin K. Shahidi-Latham, Laura van 't Veer, Paolo Vicini, Deanna L. Kroetz, Andrei Iagaru, Ella F. Jones, Geraldine Gebhart, Cornelius Cilliers, Pei Rong Evelyn Lee, Denise M. Wolf, Yanan Zheng

المصدر: Bartelink, I H, Jones, E F, Shahidi-Latham, S K, Lee, P R E, Zheng, Y, Vicini, P, van ‘t Veer, L, Wolf, D, Iagaru, A, Kroetz, D L, Prideaux, B, Cilliers, C, Thurber, G M, Wimana, Z & Gebhart, G 2019, ' Tumor Drug Penetration Measurements Could Be the Neglected Piece of the Personalized Cancer Treatment Puzzle ', Clinical Pharmacology and Therapeutics, vol. 106, no. 1, pp. 148-163 . https://doi.org/10.1002/cpt.1211
Clinical Pharmacology and Therapeutics
Clinical pharmacology and therapeutics, vol 106, iss 1
Clinical pharmacology and therapeutics, 106 (1

مصطلحات موضوعية: Review, Pharmacologie, Bioinformatics, 030226 pharmacology & pharmacy, 0302 clinical medicine, Models, Neoplasms, Medicine, Pharmacology (medical), Pharmacology & Pharmacy, Precision Medicine, Cancer, media_common, Clinical Trials as Topic, Pharmacology and Pharmaceutical Sciences, Cancer treatment, Absorption, Physiological, Molecular Imaging, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Development of treatments and therapeutic interventions, Drug, Target binding, media_common.quotation_subject, Physiological, Reviews, Antineoplastic Agents, Drug penetration, Tissue penetration, Models, Biological, Absorption, Dose-Response Relationship, 03 medical and health sciences, Rare Diseases, Genetics, Humans, Computer Simulation, Dosing, Pharmacology, Therapeutic regimen, Dose-Response Relationship, Drug, business.industry, Human Genome, Precision medicine, Biological, Orphan Drug, Good Health and Well Being, Generic health relevance, business

وصف الملف: application/pdf; 1 full-text file(s): application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd417550f0849d9df2a113a5c33d4188
https://research.vumc.nl/en/publications/b61871a4-9d89-46cc-9318-3459c4047735

المؤلفون: Dewakar Sangaraju, Sheerin K. Shahidi-Latham, Allan Jaochico

المصدر: Bioanalysis. 11(8)

مصطلحات موضوعية: Male, Electrospray ionization, Clinical Biochemistry, Urine, 030226 pharmacology & pharmacy, 01 natural sciences, Analytical Chemistry, Butyric acid, 03 medical and health sciences, chemistry.chemical_compound, Plasma, 0302 clinical medicine, Tandem Mass Spectrometry, Humans, Sample preparation, General Pharmacology, Toxicology and Pharmaceutics, Derivatization, Chromatography, 010401 analytical chemistry, Selected reaction monitoring, Short-chain fatty acid, General Medicine, Fatty Acids, Volatile, 0104 chemical sciences, Body Fluids, Medical Laboratory Technology, chemistry, Human plasma, Female, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f1ff8f29cf7abc48075810621eb0a5
https://pubmed.ncbi.nlm.nih.gov/30993998

المؤلفون: Brian Dean, Ann Ran-Ran Qin, Xiaorong Liang, Sheerin K. Shahidi-Latham, Yuzhong Deng

المصدر: Bioanalysis. 7:1069-1079

مصطلحات موضوعية: Drug, Chromatography, Chemistry, media_common.quotation_subject, Clinical Biochemistry, Connective tissue, General Medicine, Rats, Analytical Chemistry, Medical Laboratory Technology, medicine.anatomical_structure, Pharmaceutical Preparations, Drug Discovery, Freezing, Collagenase, medicine, Animals, Feasibility Studies, Collagenases, General Pharmacology, Toxicology and Pharmaceutics, medicine.drug, media_common, Homogenization (biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91049e7b3cea6f9618fe12ee8c41c1ac
https://doi.org/10.4155/bio.15.39

المؤلفون: Michael Burkard, Andrew T. Metcalf, Kristina West, Stephen E. Gould, Matthew Martinson, John Moffat, Kevin Rasor, Weiru Wang, Li Ren, Jacob Schwarz, Sheerin K. Shahidi-Latham, Patricia Pacheco, Huifen Chen, Jianping Yin, Jonas Grina, David A. Moreno, Rustam Ferdinand Garrey, James F. Blake, John Gaudino, Brian Dean

المصدر: Journal of Medicinal Chemistry. 58:1976-1991

مصطلحات موضوعية: Models, Molecular, Drug, Pyridones, media_common.quotation_subject, Molecular Conformation, Administration, Oral, Antineoplastic Agents, Pharmacology, Crystallography, X-Ray, Molecular conformation, Small Molecule Libraries, Mice, Structure-Activity Relationship, Mouse xenograft, In vivo, Drug Discovery, Animals, Structure–activity relationship, Tumor growth, Protein Kinase Inhibitors, Cell Proliferation, media_common, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Dose-Response Relationship, Drug, Drug discovery, Chemistry, Xenograft Model Antitumor Assays, Small molecule, Rats, Disease Models, Animal, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3388c0dfdd14bdd11fd71ab111383ba
https://doi.org/10.1021/jm501921k