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1
المؤلفون: Rebecca A. Gallego, Louise Bernier, Hui Chen, Sujin Cho-Schultz, Loanne Chung, Michael Collins, Matthew Del Bel, Jeff Elleraas, Cinthia Costa Jones, Ciaran N. Cronin, Martin Edwards, Xu Fang, Timothy Fisher, Mingying He, Jacqui Hoffman, Ruiduan Huo, Mehran Jalaie, Eric Johnson, Ted W. Johnson, Robert S. Kania, Manfred Kraus, Jennifer Lafontaine, Phuong Le, Tongnan Liu, Michael Maestre, Jean Matthews, Michele McTigue, Nichol Miller, Qiming Mu, Xulong Qin, Shijian Ren, Paul Richardson, Allison Rohner, Neal Sach, Li Shao, Graham Smith, Ruirui Su, Bin Sun, Sergei Timofeevski, Phuong Tran, Shuiwang Wang, Wei Wang, Ru Zhou, Jinjiang Zhu, Sajiv K. Nair
المصدر: Journal of Medicinal Chemistry. 66:4888-4909
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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2
المؤلفون: Michael R. Collins, Robert Steven Kania, Connie Fan, Sutton Scott Channing, Dominique Verhelle, Kephart Susan Elizabeth, Martin James Wythes, Shuiwang Wang, Karen A. Maegley, Lisa Nguyen, Daniel Tyler Richter, A.E. Stewart, Pei-Pei Kung, Buwen Huang, Shikhar Sharma, Shinji Yamazaki, Ya-Li Deng, Rita Grantner, Patrick Bingham, Robert Arnold Kumpf, Penney Khamphavong, Jinjiang Zhu, Dac M. Dinh, Manfred Kraus, Wei Liu, Sean Uryu, Jillian E. Spangler, Wenyue Hu, Hui Wang, Robert A. Rollins, Cody Krivacic, Zehnder Luke Raymond, Neal W. Sach, Alexei Brooun, John Sherrill, Shijian Ren, Martin A. Edwards, Huichun Zhu, Ketan S. Gajiwala, Shuibo Xin, Hovhannes J. Gukasyan
المصدر: Journal of Medicinal Chemistry. 61:650-665
مصطلحات موضوعية: 0301 basic medicine, Chemistry, Stereochemistry, Ligand (biochemistry), 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, In vivo, Drug Discovery, Lactam, Molecular Medicine, Moiety, Molecule, Solubility, Lead compound, ADME
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3
المؤلفون: Marlena Walls, Tod Smeal, Suvi T. M. Orr, Zhengyu Liu, Cheng Hengmiao, Shuiwang Wang, Kephart Susan Elizabeth, Jean Joo Matthews, Rose Ann Ferre, Neal W. Sach, Scott L. Weinrich, Doug Behenna, Sherry Niessen, Sangita M. Baxi, Deepak Dalvie, Sujin Cho-Schultz, Dac M. Dinh, Kevin Ryan, Jim Solowiej, Elaine E. Tseng, Simon Paul Planken, Sajiv Krishnan Nair, Brion W. Murray, Jun Li Feng, Jennifer Lafontaine, Pairish Mason Alan, Shijian Ren, Michelle Hemkens, Shuibo Xin, Mehran Jalaie, Tran Khanh Tuan, Robert Steven Kania, Sutton Scott Channing, William F. Vernier, Kevin K.-C. Liu, Amy Jackson-Fisher, Beth Lunney, Min-Jean Yin, Ketan S. Gajiwala, Asako Nagata, Haiwei Xu, Michael Zientek, Ru Zhou, Daniel Tyler Richter, Simon Bailey, Martin Paul Edwards, Martha A. Ornelas, Chau Almaden, John Charles Kath, Hong Shen, Theodore O. Johnson
المصدر: Journal of Medicinal Chemistry. 59:2005-2024
مصطلحات موضوعية: 0301 basic medicine, Mutation, 010405 organic chemistry, Stereochemistry, Chemistry, Mutant, medicine.disease_cause, 01 natural sciences, respiratory tract diseases, 0104 chemical sciences, 03 medical and health sciences, T790M, 030104 developmental biology, Gefitinib, Protein kinase domain, Drug Discovery, Cancer research, medicine, Molecular Medicine, Potency, Reactivity (chemistry), Erlotinib, medicine.drug
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4
المؤلفون: Michael R. Collins, Louise Bernier, Michelle Tran-Dubé, Botrous Iriny, Shijian Ren, Qingbin Zeng, Sacha Ninkovic, Neal W. Sach, John F. Braganza, Baojiang Zheng, Indrawan James Mcalpine, Baohua Li
المصدر: Tetrahedron Letters. 56:5757-5760
مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Organic Chemistry, Drug Discovery, Intramolecular cyclization, Organic chemistry, Hydroamination, Biochemistry, Medicinal chemistry, Fluoride, Stoichiometry, Catalysis
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5
المؤلفون: Pei-Pei, Kung, Patrick, Bingham, Alexei, Brooun, Michael, Collins, Ya-Li, Deng, Dac, Dinh, Connie, Fan, Ketan S, Gajiwala, Rita, Grantner, Hovhannes J, Gukasyan, Wenyue, Hu, Buwen, Huang, Robert, Kania, Susan E, Kephart, Cody, Krivacic, Robert A, Kumpf, Penney, Khamphavong, Manfred, Kraus, Wei, Liu, Karen A, Maegley, Lisa, Nguyen, Shijian, Ren, Dan, Richter, Robert A, Rollins, Neal, Sach, Shikhar, Sharma, John, Sherrill, Jillian, Spangler, Albert E, Stewart, Scott, Sutton, Sean, Uryu, Dominique, Verhelle, Hui, Wang, Shuiwang, Wang, Martin, Wythes, Shuibo, Xin, Shinji, Yamazaki, Huichun, Zhu, JinJiang, Zhu, Luke, Zehnder, Martin, Edwards
المصدر: Journal of medicinal chemistry. 61(3)
مصطلحات موضوعية: Models, Molecular, Cell Line, Tumor, Drug Design, Molecular Conformation, Administration, Oral, Biological Availability, Humans, Enhancer of Zeste Homolog 2 Protein, Isoquinolines
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6
المؤلفون: Shijian Ren, Liangliang Xue, Jiezhan Xiao, Paul F. Richardson, Phuong Le, Neal W. Sach, Shuibo Xin
المصدر: Organic Process Research & Development. 19:639-645
مصطلحات موضوعية: Column chromatography, Chemistry, Reagent, Yield (chemistry), Organic Chemistry, Scalability, Physical and Theoretical Chemistry, Combinatorial chemistry
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7
المؤلفون: Hengmiao, Cheng, Sajiv K, Nair, Brion W, Murray, Chau, Almaden, Simon, Bailey, Sangita, Baxi, Doug, Behenna, Sujin, Cho-Schultz, Deepak, Dalvie, Dac M, Dinh, Martin P, Edwards, Jun Li, Feng, Rose Ann, Ferre, Ketan S, Gajiwala, Michelle D, Hemkens, Amy, Jackson-Fisher, Mehran, Jalaie, Ted O, Johnson, Robert S, Kania, Susan, Kephart, Jennifer, Lafontaine, Beth, Lunney, Kevin K-C, Liu, Zhengyu, Liu, Jean, Matthews, Asako, Nagata, Sherry, Niessen, Martha A, Ornelas, Suvi T M, Orr, Mason, Pairish, Simon, Planken, Shijian, Ren, Daniel, Richter, Kevin, Ryan, Neal, Sach, Hong, Shen, Tod, Smeal, Jim, Solowiej, Scott, Sutton, Khanh, Tran, Elaine, Tseng, William, Vernier, Marlena, Walls, Shuiwang, Wang, Scott L, Weinrich, Shuibo, Xin, Haiwei, Xu, Min-Jean, Yin, Michael, Zientek, Ru, Zhou, John C, Kath
المصدر: Journal of medicinal chemistry. 59(5)
مصطلحات موضوعية: Models, Molecular, Lung Neoplasms, Dose-Response Relationship, Drug, Molecular Structure, ErbB Receptors, Structure-Activity Relationship, Pyrimidines, Carcinoma, Non-Small-Cell Lung, Drug Discovery, Mutation, Tumor Cells, Cultured, Humans, Mutant Proteins, Pyrroles, Protein Kinase Inhibitors
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8
المؤلفون: Shijian Ren, Zhiquan Shen, Jun Ling
المصدر: European Polymer Journal. 40:647-650
مصطلحات موضوعية: chemistry.chemical_classification, Polymers and Plastics, Organic Chemistry, General Physics and Astronomy, chemistry.chemical_element, Solution polymerization, Polymer, Chloride, Ring-opening polymerization, Catalysis, chemistry.chemical_compound, chemistry, Polymerization, Polymer chemistry, Materials Chemistry, Lanthanum, medicine, Methylene, medicine.drug
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9
المؤلفون: Fen Wang, Paul G. Richardson, Sarah Johnson, Quyen-Quyen T. Do, Yadong Wan, Indrawan James Mcalpine, Shijian Ren, Stephanie Scales, Qiyue Hu, John F. Braganza, Baojiang Zheng, Darius J. Faizi
المصدر: Organic letters. 15(9)
مصطلحات موضوعية: Pyrazine, Stereochemistry, Organic Chemistry, Regioselectivity, Electrons, Stereoisomerism, Biochemistry, chemistry.chemical_compound, chemistry, Nucleophile, Nucleophilic aromatic substitution, Pyrazines, mental disorders, Hydrocarbons, Chlorinated, Physical and Theoretical Chemistry, Amines, Oxidation-Reduction, psychological phenomena and processes
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10
المؤلفون: Zhiquan Shen, Jun Ling, Shijian Ren
المصدر: e-Polymers. 10
مصطلحات موضوعية: Tris, Materials science, Polymers and Plastics, General Chemical Engineering, chemistry.chemical_element, Block (periodic table), Catalysis, Solvent, chemistry.chemical_compound, chemistry, Polymer chemistry, Lanthanum, Copolymer, Proton NMR, Carbonate, Physical and Theoretical Chemistry
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::566a46c6184607b2fd31326ade0bb8b3
https://doi.org/10.1515/epoly.2010.10.1.270