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1دورية أكاديمية
المؤلفون: Adahir Labrador-Garrido, Siying Zhong, Laura Hughes, Shikara Keshiya, Woojin S. Kim, Glenda M. Halliday, Nicolas Dzamko
المصدر: Frontiers in Cellular Neuroscience, Vol 17 (2023)
مصطلحات موضوعية: Parkinson's disease, GCase, alpha-synuclein, pluripotent stem cells, LRRK2, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Diba Ahmadi Rastegar, Laura P. Hughes, Gayathri Perera, Shikara Keshiya, Siying Zhong, Jianqun Gao, Glenda M. Halliday, Birgitt Schüle, Nicolas Dzamko
المصدر: npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-11 (2022)
مصطلحات موضوعية: Neurology. Diseases of the nervous system, RC346-429
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2373-8057
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3دورية أكاديمية
المؤلفون: Ye Zhao, Shikara Keshiya, Farzaneh Atashrazm, Jianqun Gao, Lars M. Ittner, Dario R. Alessi, Glenda M. Halliday, Yuhong Fu, Nicolas Dzamko
المصدر: Neurobiology of Disease, Vol 120, Iss , Pp 76-87 (2018)
مصطلحات موضوعية: LRRK2, Phosphorylation, α-Synuclein, Knockin mouse, Striatum, Astrocytes, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
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4دورية أكاديميةLRRK2 kinase inhibitors reduce alpha-synuclein in human neuronal cell lines with the G2019S mutation
المؤلفون: Ye Zhao, Shikara Keshiya, Gayathri Perera, Lauren Schramko, Glenda M. Halliday, Nicolas Dzamko
المصدر: Neurobiology of Disease, Vol 144, Iss , Pp 105049- (2020)
مصطلحات موضوعية: LRRK2, Parkinson's disease, Kinase inhibitors, α-synuclein, Pluripotent stem cells, Lysosome, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
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5
المؤلفون: Leanne Stokes, Belinda L. Curtis, Shikara Keshiya, Tracey Berg, Reece A. Sophocleous, Stephen J Curtis, Ronald Sluyter, Rocio K. Finol-Urdaneta, Aine Seavers, Mark Dowton, Vanessa Sluyter, Rachael Bartlett, Lachlan Bell, Lezanne Ooi
المصدر: Br J Pharmacol
مصطلحات موضوعية: 0301 basic medicine, Agonist, Purinergic P2X Receptor Antagonists, medicine.drug_class, Pharmacology, Biology, Partial agonist, law.invention, 03 medical and health sciences, 0302 clinical medicine, Adenosine Triphosphate, Dogs, law, medicine, Potency, Animals, Humans, Receptor, Purinergic receptor, HEK 293 cells, Research Papers, 030104 developmental biology, HEK293 Cells, Recombinant DNA, Receptors, Purinergic P2X7, Receptors, Purinergic P2X4, 030217 neurology & neurosurgery
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::740e9b239fac14416e1f97b2ef876423
https://europepmc.org/articles/PMC7236074/ -
6LRRK2 kinase inhibitors reduce alpha-synuclein in human neuronal cell lines with the G2019S mutation
المؤلفون: Lauren Schramko, Glenda M. Halliday, Gayathri Perera, Nicolas Dzamko, Ye Zhao, Shikara Keshiya
المصدر: Neurobiology of Disease, Vol 144, Iss, Pp 105049-(2020)
مصطلحات موضوعية: 0301 basic medicine, Parkinson's disease, Induced Pluripotent Stem Cells, Biology, In Vitro Techniques, medicine.disease_cause, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, lcsh:RC321-571, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Protein Aggregates, α-synuclein, 0302 clinical medicine, Pluripotent stem cells, Neural Stem Cells, Lysosome, medicine, Humans, Induced pluripotent stem cell, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Protein Kinase Inhibitors, Alpha-synuclein, Neurons, Mutation, LRRK2, Parkinson Disease, Fibroblasts, medicine.disease, Neural stem cell, nervous system diseases, 030104 developmental biology, medicine.anatomical_structure, Neurology, chemistry, Kinase inhibitors, Cell culture, Cancer research, alpha-Synuclein, 030217 neurology & neurosurgery