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المؤلفون: Yukimasa Shiotsu, Shiro Soga, Shiro Akinaga, Yutaka Kanda, Hiroshi Nakagawa, Toshihiro Seike, Hisashi Tagaya, Toshihiko Ishii, Takayuki Nakashima
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05eac44feed9bb3a0c2e4e510ae4018f
https://doi.org/10.1158/1078-0432.22442663 -
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المؤلفون: Yukimasa Shiotsu, Shiro Soga, Shiro Akinaga, Yutaka Kanda, Hiroshi Nakagawa, Toshihiro Seike, Hisashi Tagaya, Toshihiko Ishii, Takayuki Nakashima
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b9b7f93cb765894d34df7b7b1e20ec
https://doi.org/10.1158/1078-0432.c.6519338 -
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المؤلفون: Yasuo Watanabe, Shiro Soga, Hiroshi Nakagawa, Hideyuki Onodera, Imaizumi Takamichi, Kyoichiro Iida, Ran Hori
المصدر: The Journal of Antibiotics. 70:675-679
مصطلحات موضوعية: Carbamate, Stereochemistry, Carboxylic acid, medicine.medical_treatment, Antineoplastic Agents, 010402 general chemistry, 01 natural sciences, Structure-Activity Relationship, chemistry.chemical_compound, Cell Line, Tumor, Amide, Drug Discovery, medicine, Humans, Urea, Moiety, Cell Proliferation, Pyrans, Pharmacology, chemistry.chemical_classification, Natural product, 010405 organic chemistry, Amides, 0104 chemical sciences, chemistry, Drug Design, Carbamates, Fatty Alcohols, Herboxidiene, Curtius rearrangement
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المؤلفون: Shiro Soga
المصدر: Folia Pharmacologica Japonica. 141:9-14
مصطلحات موضوعية: Pharmacology, Clinical Trials as Topic, biology, Drug discovery, business.industry, Chemistry, Lactams, Macrocyclic, Morpholines, Research, Computational biology, Hsp90, Hsp90 inhibitor, Text mining, Neoplasms, Heat shock protein, Drug Discovery, Benzoquinones, biology.protein, Animals, Humans, HSP90 Heat-Shock Proteins, Molecular Targeted Therapy, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e04cd8a2f330cd1a4f7ad0485ae91f74
https://doi.org/10.1254/fpj.141.9 -
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المؤلفون: Shiro Akinaga, Yukimasa Shiotsu, Shiro Soga
المصدر: Current Pharmaceutical Design. 19:366-376
مصطلحات موضوعية: Pharmacology, biology, Kinase, Morpholines, Cancer, Antineoplastic Agents, Geldanamycin, Bioinformatics, medicine.disease, Hsp90, Small molecule, Radicicol, Clinical trial, chemistry.chemical_compound, chemistry, Heat shock protein, Neoplasms, Drug Discovery, biology.protein, medicine, Animals, Humans, HSP90 Heat-Shock Proteins
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81e3bf60ea35a93ebb36ea1f5df81c6
https://doi.org/10.2174/1381612811306030366 -
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المؤلفون: Shiro Soga, Len Neckers, Akihiro Yano, Shinji Tsutsumi, Hiroyuki Osada, Min-Jung Lee, Jane B. Trepel
المصدر: Proceedings of the National Academy of Sciences. 105:15541-15546
مصطلحات موضوعية: Male, Lactams, Macrocyclic, Proto-Oncogene Proteins pp60(c-src), Osteoclasts, Bone Neoplasms, Biology, Hsp90 inhibitor, Osteoclast maturation, Mice, Prostate cancer, Osteoclast, Benzoquinones, polycyclic compounds, medicine, Animals, Immunoprecipitation, HSP90 Heat-Shock Proteins, Phosphorylation, Protein kinase B, Multidisciplinary, Carcinoma, Integrin beta3, Prostatic Neoplasms, Biological Sciences, medicine.disease, Mice, Inbred C57BL, Oncogene Protein v-akt, Dasatinib, medicine.anatomical_structure, Cancer cell, Cancer research, Signal Transduction, Proto-oncogene tyrosine-protein kinase Src, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f621428a36b318cb474874656742fd
https://doi.org/10.1073/pnas.0805354105 -
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المؤلفون: Shiro Akinaga, Yukimasa Shiotsu, Shiro Soga
المصدر: Leukemia & Lymphoma. 43:961-968
مصطلحات موضوعية: Cancer Research, Leukemia, biology, Chemistry, Fusion Proteins, bcr-abl, Antagonist, Hematology, medicine.disease, Hsp90, Lymphoma, Lactones, Oncology, hemic and lymphatic diseases, Heat shock protein, medicine, biology.protein, Cancer research, Humans, Chaperone complex, HSP90 Heat-Shock Proteins
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المؤلفون: Sreenath V. Sharma, Junichi Kurebayashi, Shiro Akinaga, Yoji Ikuina, Leonard M. Neckers, Tatsuya Tamaoki, Yukimasa Shiotsu, Chikara Murakata, Harunobu Tahara, Theodor W. Schulte, Shiro Soga, Makiko Shimizu, Kazuo Yamaguchi
المصدر: Cancer Chemotherapy and Pharmacology. 48:435-445
مصطلحات موضوعية: Cancer Research, Mice, Nude, Apoptosis, Breast Neoplasms, Toxicology, Lactones, Mice, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Oximes, Tumor Cells, Cultured, polycyclic compounds, Animals, Humans, Pharmacology (medical), HSP90 Heat-Shock Proteins, Enzyme Inhibitors, Pharmacology, Mice, Inbred BALB C, biology, Ansamycin, Stereoisomerism, Biological activity, Genes, erbB-2, Geldanamycin, Hsp90, In vitro, Radicicol, Gene Expression Regulation, Oncology, chemistry, Biochemistry, Herbimycin, Injections, Intravenous, biology.protein, Cancer research, Female, Macrolides
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المؤلفون: Hiroshi Sonoo, Shiro Akinaga, Shiro Soga, Masafumi Kurosumi, Junichi Kurebayashi, Takemi Otsuki
المصدر: Japanese Journal of Cancer Research : Gann
مصطلحات موضوعية: Vascular Endothelial Growth Factor A, Cancer Research, Time Factors, Angiogenesis, medicine.medical_treatment, Apoptosis, Endothelial Growth Factors, chemistry.chemical_compound, Lactones, Mice, Breast cancer, Tumor Cells, Cultured, Hypoxia, Lymphokines, Neovascularization, Pathologic, Vascular Endothelial Growth Factors, Nuclear Proteins, Radicicol, Vascular endothelial growth factor, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Vascular endothelial growth factor A, Oncology, Hypoxia-inducible factors, Female, Hypoxia-Inducible Factor 1, Macrolides, Growth inhibition, Cell Division, medicine.medical_specialty, Blotting, Western, Transplantation, Heterologous, Mice, Nude, Breast Neoplasms, Biology, Article, Internal medicine, medicine, Animals, Humans, RNA, Messenger, Dose-Response Relationship, Drug, Growth factor, Radicicol Derivative KF58333, Hypoxia-Inducible Factor 1, alpha Subunit, Endocrinology, Ki-67 Antigen, chemistry, Hypoxia‐inducible factor‐1, Cancer research, Neoplasm Transplantation, Transcription Factors
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المؤلفون: Simone Juliger, Yukimasa Shiotsu, Simon P. Joel, Lenushka Maharaj, Takayuki Nakashima, Toshihiro Seike, James D. Cavenagh, Shiro Soga, Toshihiko Ishii, Shiro Akinaga
المصدر: Blood Cancer Journal
مصطلحات موضوعية: Bortezomib, Cell growth, business.industry, apoptosis, Hematology, Pharmacology, medicine.disease, Hsp90 inhibitor, medicine.anatomical_structure, proteasome, Oncology, Proteasome, In vivo, hemic and lymphatic diseases, medicine, Proteasome inhibitor, Original Article, Bone marrow, heat shock protein 90, business, Multiple myeloma, medicine.drug