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1دورية أكاديمية
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2دورية أكاديمية
المؤلفون: Shoichet, Brian K, Craik, Charles S
المصدر: Science. 382(6671)
مصطلحات موضوعية: Humans, COVID-19, Pandemics, COVID-19 Drug Treatment, Drug Discovery, Coronavirus Protease Inhibitors, Coronavirus 3C Proteases, General Science & Technology
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/37z1g88z
https://escholarship.org/content/qt37z1g88z/qt37z1g88z.pdf -
3دورية أكاديمية
المؤلفون: Fink, Elissa A, Bardine, Conner, Gahbauer, Stefan, Singh, Isha, Detomasi, Tyler C, White, Kris, Gu, Shuo, Wan, Xiaobo, Chen, Jun, Ary, Beatrice, Glenn, Isabella, O'Connell, Joseph, O'Donnell, Henry, Fajtová, Pavla, Lyu, Jiankun, Vigneron, Seth, Young, Nicholas J, Kondratov, Ivan S, Alisoltani, Arghavan, Simons, Lacy M, Lorenzo‐Redondo, Ramon, Ozer, Egon A, Hultquist, Judd F, O'Donoghue, Anthony J, Moroz, Yurii S, Taunton, Jack, Renslo, Adam R, Irwin, John J, García‐Sastre, Adolfo, Shoichet, Brian K, Craik, Charles S
المصدر: Protein Science. 32(8)
مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Lung, Prevention, Emerging Infectious Diseases, Infectious Diseases, Vaccine Related, Biodefense, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, Humans, COVID-19, SARS-CoV-2, Pandemics, Protease Inhibitors, Molecular Docking Simulation, Viral Nonstructural Proteins, Antiviral Agents, major protease, SARS-COV-2, structure-based inhibitor, discoverydockinganti-viral, Biochemistry and Cell Biology, Computation Theory and Mathematics, Other Information and Computing Sciences, Biophysics, Biochemistry and cell biology, Medicinal and biomolecular chemistry
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/61h336z6
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4دورية أكاديمية
المؤلفون: Donders, Eric N, Slaughter, Kai V, Dank, Christian, Ganesh, Ahil N, Shoichet, Brian K, Lautens, Mark, Shoichet, Molly S
المصدر: Advanced Science. 10(13)
مصطلحات موضوعية: Medical Biotechnology, Biomedical and Clinical Sciences, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Fulvestrant, Colloids, Endosomes, Lysosomes, colloidal drug aggregates, drug delivery, endosomal disruption, fulvestrant, nanoparticles
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/4bs9s258
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5دورية أكاديمية
المؤلفون: Singh, Isha, Seth, Anubha, Billesbølle, Christian B, Braz, Joao, Rodriguiz, Ramona M, Roy, Kasturi, Bekele, Bethlehem, Craik, Veronica, Huang, Xi-Ping, Boytsov, Danila, Pogorelov, Vladimir M, Lak, Parnian, O'Donnell, Henry, Sandtner, Walter, Irwin, John J, Roth, Bryan L, Basbaum, Allan I, Wetsel, William C, Manglik, Aashish, Shoichet, Brian K, Rudnick, Gary
المصدر: Cell. 186(10)
مصطلحات موضوعية: Animals, Mice, Serotonin, Fluoxetine, Ibogaine, Molecular Conformation, Serotonin Plasma Membrane Transport Proteins, Small Molecule Libraries, Selective Serotonin Reuptake Inhibitors, depression, docking, functional selectivity, serotonin transporter, ultra-large libraries, Substance Misuse, Neurosciences, Drug Abuse (NIDA only), Biological Sciences, Medical and Health Sciences, Developmental Biology
URL الوصول: https://escholarship.org/uc/item/5cg0t59n
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6دورية أكاديمية
المؤلفون: Gahbauer, Stefan, Correy, Galen J, Schuller, Marion, Ferla, Matteo P, Doruk, Yagmur Umay, Rachman, Moira, Wu, Taiasean, Diolaiti, Morgan, Wang, Siyi, Neitz, R Jeffrey, Fearon, Daren, Radchenko, Dmytro S, Moroz, Yurii S, Irwin, John J, Renslo, Adam R, Taylor, Jenny C, Gestwicki, Jason E, von Delft, Frank, Ashworth, Alan, Ahel, Ivan, Shoichet, Brian K, Fraser, James S
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 120(2)
مصطلحات موضوعية: Theory Of Computation, Biochemistry and Cell Biology, Biological Sciences, Medicinal and Biomolecular Chemistry, Chemical Sciences, Built Environment and Design, Information and Computing Sciences, Design, Emerging Infectious Diseases, Vaccine Related, Biodefense, Prevention, Lung, Infectious Diseases, Pneumonia & Influenza, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Generic health relevance, Humans, SARS-CoV-2, COVID-19, Crystallography, Pandemics, Ligands, Molecular Docking Simulation, Protease Inhibitors, Antiviral Agents, coronavirus, macrodomain, virtual screening, fragment-based drug discovery
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/3qr8j49t
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7دورية أكاديمية
المؤلفون: Haas, Kelsey M, McGregor, Michael J, Bouhaddou, Mehdi, Polacco, Benjamin J, Kim, Eun-Young, Nguyen, Thong T, Newton, Billy W, Urbanowski, Matthew, Kim, Heejin, Williams, Michael AP, Rezelj, Veronica V, Hardy, Alexandra, Fossati, Andrea, Stevenson, Erica J, Sukerman, Ellie, Kim, Tiffany, Penugonda, Sudhir, Moreno, Elena, Braberg, Hannes, Zhou, Yuan, Metreveli, Giorgi, Harjai, Bhavya, Tummino, Tia A, Melnyk, James E, Soucheray, Margaret, Batra, Jyoti, Pache, Lars, Martin-Sancho, Laura, Carlson-Stevermer, Jared, Jureka, Alexander S, Basler, Christopher F, Shokat, Kevan M, Shoichet, Brian K, Shriver, Leah P, Johnson, Jeffrey R, Shaw, Megan L, Chanda, Sumit K, Roden, Dan M, Carter, Tonia C, Kottyan, Leah C, Chisholm, Rex L, Pacheco, Jennifer A, Smith, Maureen E, Schrodi, Steven J, Albrecht, Randy A, Vignuzzi, Marco, Zuliani-Alvarez, Lorena, Swaney, Danielle L, Eckhardt, Manon, Wolinsky, Steven M, White, Kris M, Hultquist, Judd F, Kaake, Robyn M, García-Sastre, Adolfo, Krogan, Nevan J
المصدر: Nature Communications. 14(1)
مصطلحات موضوعية: Microbiology, Medical Microbiology, Biomedical and Clinical Sciences, Biological Sciences, Infectious Diseases, Prevention, Emerging Infectious Diseases, Vaccine Related, Influenza, Pneumonia & Influenza, Biodefense, Biotechnology, 2.1 Biological and endogenous factors, 2.2 Factors relating to the physical environment, Aetiology, Infection, Humans, Influenza A virus, Influenza, Human, Influenza A Virus, H5N1 Subtype, Influenza A Virus, H3N2 Subtype, Proteomics, Virus Replication, COVID-19, SARS-CoV-2, Antiviral Agents, Host-Pathogen Interactions
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/5h41d3sv
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8دورية أكاديمية
المؤلفون: Yang, Junjiao, Xiao, Yinghong, Lidsky, Peter V, Wu, Chien-Ting, Bonser, Luke R, Peng, Shiming, Garcia-Knight, Miguel A, Tassetto, Michel, Chung, Chan-I, Li, Xiaoquan, Nakayama, Tsuguhisa, Lee, Ivan T, Nayak, Jayakar V, Ghias, Khadija, Hargett, Kirsten L, Shoichet, Brian K, Erle, David J, Jackson, Peter K, Andino, Raul, Shu, Xiaokun
المصدر: Nature Microbiology. 8(1)
مصطلحات موضوعية: Emerging Infectious Diseases, Lung, Prevention, Pneumonia & Influenza, Pneumonia, Infectious Diseases, Development of treatments and therapeutic interventions, 2.1 Biological and endogenous factors, Aetiology, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, Chlorocebus aethiops, Mice, Humans, Animals, SARS-CoV-2, COVID-19, Vero Cells, Angiotensin-Converting Enzyme 2, Peptidyl-Dipeptidase A, Antiviral Agents, Microbiology, Medical Microbiology
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/1gz923gn
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9دورية أكاديمية
المؤلفون: Kaplan, Anat Levit, Confair, Danielle N, Kim, Kuglae, Barros-Álvarez, Ximena, Rodriguiz, Ramona M, Yang, Ying, Kweon, Oh Sang, Che, Tao, McCorvy, John D, Kamber, David N, Phelan, James P, Martins, Luan Carvalho, Pogorelov, Vladimir M, DiBerto, Jeffrey F, Slocum, Samuel T, Huang, Xi-Ping, Kumar, Jain Manish, Robertson, Michael J, Panova, Ouliana, Seven, Alpay B, Wetsel, Autumn Q, Wetsel, William C, Irwin, John J, Skiniotis, Georgios, Shoichet, Brian K, Roth, Bryan L, Ellman, Jonathan A
المصدر: Nature. 610(7932)
مصطلحات موضوعية: Theory Of Computation, Information and Computing Sciences, Medicinal and Biomolecular Chemistry, Chemical Sciences, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Animals, Mice, Antidepressive Agents, Cryoelectron Microscopy, Fluoxetine, Hallucinogens, Ligands, Pyrrolidines, Receptor, Serotonin, 5-HT2A, Small Molecule Libraries, General Science & Technology
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/87f9q9sd
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10دورية أكاديمية
المؤلفون: Fink, Elissa A, Xu, Jun, Hübner, Harald, Braz, Joao M, Seemann, Philipp, Avet, Charlotte, Craik, Veronica, Weikert, Dorothee, Schmidt, Maximilian F, Webb, Chase M, Tolmachova, Nataliya A, Moroz, Yurii S, Huang, Xi-Ping, Kalyanaraman, Chakrapani, Gahbauer, Stefan, Chen, Geng, Liu, Zheng, Jacobson, Matthew P, Irwin, John J, Bouvier, Michel, Du, Yang, Shoichet, Brian K, Basbaum, Allan I, Gmeiner, Peter
المصدر: Science. 377(6614)
مصطلحات موضوعية: Adrenergic alpha-2 Receptor Agonists, Analgesics, Non-Narcotic, Animals, Dexmedetomidine, Drug Design, Drug Discovery, Humans, Ligands, Mice, Molecular Docking Simulation, Pain, Pain Management, Structure-Activity Relationship, Neurosciences, Pain Research, Chronic Pain, General Science & Technology
URL الوصول: https://escholarship.org/uc/item/6r0990sd