المؤلفون: Shivkumar Biradar, Thomas E. Smithgall, Yash Agarwal, Moses T. Bility, Isabella Castronova, Robbie B. Mailliard, Antu Das, Shu St, Samal J, Sebastian Ho, Cole Beatty

مصطلحات موضوعية: T cell, virus diseases, Spleen, Viremia, Immune dysregulation, Biology, medicine.disease_cause, medicine.disease, medicine.anatomical_structure, Immune system, Viral replication, Humanized mouse, Immunology, medicine, Bone marrow

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb1a1662b0ac03877f21b862d11feb7
https://doi.org/10.1101/2021.01.21.427631

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المؤلفون: Biradar S; Department of Infectious Diseases and Microbiology, University of Pittsburgh, School of Public Health, Pittsburgh, PA, USA., Agarwal Y; Department of Infectious Diseases and Microbiology, University of Pittsburgh, School of Public Health, Pittsburgh, PA, USA., Das A; Department of Infectious Diseases and Microbiology, University of Pittsburgh, School of Public Health, Pittsburgh, PA, USA., Shu ST; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Samal J; Department of Infectious Diseases and Microbiology, University of Pittsburgh, School of Public Health, Pittsburgh, PA, USA., Ho S; Department of Infectious Diseases and Microbiology, University of Pittsburgh, School of Public Health, Pittsburgh, PA, USA., Kelly N; Department of Infectious Diseases and Microbiology, University of Pittsburgh, School of Public Health, Pittsburgh, PA, USA., Mahesh D; Department of Infectious Diseases and Microbiology, University of Pittsburgh, School of Public Health, Pittsburgh, PA, USA., Teredesai S; Department of Infectious Diseases and Microbiology, University of Pittsburgh, School of Public Health, Pittsburgh, PA, USA., Castronova I; Department of Infectious Diseases and Microbiology, University of Pittsburgh, School of Public Health, Pittsburgh, PA, USA., Mussina L; Department of Infectious Diseases and Microbiology, University of Pittsburgh, School of Public Health, Pittsburgh, PA, USA., Mailliard RB; Department of Infectious Diseases and Microbiology, University of Pittsburgh, School of Public Health, Pittsburgh, PA, USA., Smithgall TE; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Bility MT; Department of Infectious Diseases and Microbiology, University of Pittsburgh, School of Public Health, Pittsburgh, PA, USA; Department of Microbiology, Howard University, Washington, DC, USA. Electronic address: moses.bility@howard.edu.

المصدر: Virology [Virology] 2024 Oct; Vol. 598, pp. 110192. Date of Electronic Publication: 2024 Jul 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0110674 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0341 (Electronic) Linking ISSN: 00426822 NLM ISO Abbreviation: Virology Subsets: MEDLINE

مواضيع طبية MeSH: nef Gene Products, Human Immunodeficiency Virus*/genetics , nef Gene Products, Human Immunodeficiency Virus*/immunology , HIV Infections*/immunology , HIV Infections*/virology , Viremia*/immunology , Spleen*/immunology , Spleen*/virology , Disease Models, Animal* , HIV-1*/immunology , HIV-1*/genetics , HIV-1*/physiology , Liver*/virology , Liver*/immunology , Liver*/pathology , Virus Replication*, Animals ; Mice ; Humans ; Bone Marrow/virology ; Bone Marrow/immunology ; Thymus Gland/immunology ; Thymus Gland/virology ; Immunity, Innate

المؤلفون: Emert-Sedlak LA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA., Tice CM; Fox Chase Therapeutics Discovery, Inc., Pennsylvania Biotechnology Center, Doylestown, PA 18902, USA., Shi H; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA., Alvarado JJ; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA., Shu ST; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA., Reitz AB; Fox Chase Therapeutics Discovery, Inc., Pennsylvania Biotechnology Center, Doylestown, PA 18902, USA., Smithgall TE; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA. Electronic address: tsmithga@pitt.edu.

المصدر: Cell chemical biology [Cell Chem Biol] 2024 Apr 18; Vol. 31 (4), pp. 658-668.e14. Date of Electronic Publication: 2024 Mar 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: HIV-1*, T-Lymphocytes ; Down-Regulation ; Cell Membrane ; Virus Replication ; Proteolysis ; Ubiquitin-Protein Ligases

المؤلفون: Roy CN; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Shu ST; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Kline C; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Rigatti L; Division of Laboratory Animal Resources, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Smithgall TE; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Ambrose Z; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. zaa4@pitt.edu.

المصدر: Scientific reports [Sci Rep] 2023 Oct 10; Vol. 13 (1), pp. 17067. Date of Electronic Publication: 2023 Oct 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: HIV-1* , HIV Infections*, Mice ; Humans ; Animals ; Child ; Disease Models, Animal ; Thymus Gland/pathology ; CD4-Positive T-Lymphocytes ; Mice, SCID ; Mice, Inbred NOD

المؤلفون: Emert-Sedlak LA, Tice CM, Shi H, Alvarado JJ, Shu ST, Reitz AB, Smithgall TE

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Sep 05. Date of Electronic Publication: 2023 Sep 05.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Satjawathee T; International College for Interdisciplinary Studies, Payap University, Super-Highway Chiang Mai-Lumpang Road, Amphur Muang, Chiang Mai 50000, Thailand., Strombeck SD; The School of Business, Rocklin Campus, William Jessup University, 2121 University Avenue, Rocklin, CA 95765, USA., Shu ST; International College for Interdisciplinary Studies, Payap University, Super-Highway Chiang Mai-Lumpang Road, Amphur Muang, Chiang Mai 50000, Thailand., Chang CH; Department of Kinesiology, Health, and Leisure Studies, National University of Kaohsiung, 700 Kaohsiung University Rd., Nanzih District, Kaohsiung 811, Taiwan.

المصدر: Behavioral sciences (Basel, Switzerland) [Behav Sci (Basel)] 2023 Apr 04; Vol. 13 (4). Date of Electronic Publication: 2023 Apr 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101576826 Publication Model: Electronic Cited Medium: Print ISSN: 2076-328X (Print) Linking ISSN: 2076328X NLM ISO Abbreviation: Behav Sci (Basel) Subsets: PubMed not MEDLINE

المؤلفون: Emert-Sedlak LA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA., Shi H; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA., Tice CM; Fox Chase Chemical Diversity Center, Inc., Pennsylvania Biotechnology Center, Doylestown, PA 18902, USA., Chen L; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA., Alvarado JJ; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA., Shu ST; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA., Du S; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA., Thomas CE; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA., Wrobel JE; Fox Chase Chemical Diversity Center, Inc., Pennsylvania Biotechnology Center, Doylestown, PA 18902, USA., Reitz AB; Fox Chase Chemical Diversity Center, Inc., Pennsylvania Biotechnology Center, Doylestown, PA 18902, USA., Smithgall TE; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.

المصدر: Viruses [Viruses] 2022 Sep 13; Vol. 14 (9). Date of Electronic Publication: 2022 Sep 13.

نوع المنشور: Journal Article; Review; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

مواضيع طبية MeSH: HIV Infections*/drug therapy , HIV Seropositivity* , HIV-1*/physiology, Anti-Retroviral Agents/therapeutic use ; Drug Discovery ; Humans ; Virulence Factors ; nef Gene Products, Human Immunodeficiency Virus

المؤلفون: Shu ST; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA., Li WF; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA., Smithgall TE; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.

المصدر: Bio-protocol [Bio Protoc] 2021 Jul 05; Vol. 11 (13), pp. e4068. Date of Electronic Publication: 2021 Jul 05 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Bio-protocol LLC Country of Publication: United States NLM ID: 101635102 Publication Model: eCollection Cited Medium: Internet ISSN: 2331-8325 (Electronic) Linking ISSN: 23318325 NLM ISO Abbreviation: Bio Protoc Subsets: PubMed not MEDLINE

المؤلفون: Staudt RP; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Alvarado JJ; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Emert-Sedlak LA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Shi H; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Shu ST; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Wales TE; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, USA., Engen JR; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, USA., Smithgall TE; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. Electronic address: tsmithga@pitt.edu.

المصدر: The Journal of biological chemistry [J Biol Chem] 2020 Oct 30; Vol. 295 (44), pp. 15158-15171. Date of Electronic Publication: 2020 Aug 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Review

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Anti-HIV Agents/*pharmacology , HIV-1/*enzymology , Protein Kinase Inhibitors/*pharmacology , Protein Kinases/*metabolism , nef Gene Products, Human Immunodeficiency Virus/*metabolism, CD4 Antigens/metabolism ; Crystallography, X-Ray ; Down-Regulation ; HIV-1/pathogenicity ; Immune Evasion ; Major Histocompatibility Complex ; Membrane Proteins/metabolism ; Protein Kinases/drug effects ; Protein Transport ; Structure-Activity Relationship ; nef Gene Products, Human Immunodeficiency Virus/chemistry