المؤلفون: Chin Thing J Ong, Qiangze Hoi, Alexis Jiaying Khng, Naoto Takahashi, Zhu En Chan, Audrey S.M. Teo, Axel M. Hillmer, David A. Fruman, Charles Chuah, Wei Jia W Soon, Patrick Tan, Wee Joo Chng, Simeen Malik, King Pan Ng, Kian Leong Lee, Ravi Bhatia, Pauline C. Ng, Tun Kiat Ko, Cheryl Xueli Chan, Xiu Ting Heng, Kim Jiajing Xie, Joanna H.J. Tan, Thushangi N. Pathiraja, Wee Yang Meah, Sheila Xinxuan Soh, Chiea Chuen Khor, Yee Yen Sia, S. Tiong Ong, Oscar Velazquez Camacho, Asif Javed, Xingliang Liu

المصدر: Blood. 135(26)

مصطلحات موضوعية: 0301 basic medicine, Chromatin Immunoprecipitation, Cellular differentiation, Immunology, Gene Dosage, Decitabine, Datasets as Topic, Biology, Biochemistry, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Exome Sequencing, medicine, Humans, Enhancer of Zeste Homolog 2 Protein, Epigenetics, Exome sequencing, Polycomb Repressive Complex 1, Whole Genome Sequencing, Gene Expression Regulation, Leukemic, Polycomb Repressive Complex 2, Myeloid leukemia, High-Throughput Nucleotide Sequencing, Cell Differentiation, Cell Biology, Hematology, DNA Methylation, 030104 developmental biology, Gene Ontology, 030220 oncology & carcinogenesis, DNA methylation, Mutation, Cancer research, Blast Crisis, Reprogramming, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d59614c263f519893a3cec6b928580e4
https://pubmed.ncbi.nlm.nih.gov/32585023

المؤلفون: Clarinda Chua, Hui Maan Seah, Pauline C. Ng, Jack L. Ow, Shimin Ang, Simeen Malik, Dianne Y.S. Poh, Yang Sun Chan, Patrick Tan, Christopher W. Wong, Alexander Lezhava, James Z.Z. Qu, Yasmin Bylstra, Daniel Shao-Weng Tan, Tony Kiat Hon Lim, Iain Beehuat Tan, Seow Eng Lee, Lionel Lim, Rachel Ten, Cindy E. Ching, Katie H.T. Cheung, Sophie R. Wang, Qiangze Hoi, Lu Pan, Cassandra Zhengxuan He, Arun George Devasia, Dharuman Perumal

المصدر: The Journal of Molecular Diagnostics. 18:416-424

مصطلحات موضوعية: 0301 basic medicine, Colorectal cancer, DNA Mutational Analysis, Biology, medicine.disease_cause, Polymorphism, Single Nucleotide, Sensitivity and Specificity, DNA sequencing, Pathology and Forensic Medicine, 03 medical and health sciences, 0302 clinical medicine, INDEL Mutation, Reference Values, Biomarkers, Tumor, medicine, Humans, Gastrointestinal cancer, Indel, Gene, Allele frequency, Gastrointestinal Neoplasms, Genetics, Mutation, High-Throughput Nucleotide Sequencing, Reproducibility of Results, medicine.disease, 030104 developmental biology, 030220 oncology & carcinogenesis, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7db2aa463566a0247b681a200446388
https://doi.org/10.1016/j.jmoldx.2016.01.006

المؤلفون: Joanne Ngeow, M.H. Tan, Kiat Hon Lim, Patrick Tan, Bin Tean Teh, Simeen Malik, Wei Lin Goh, Weng Khong Lim, Mohamad Farid, Nur Diana Binte Ishak, Sathiyamoorthy Selvarajan, Jonathan Yi Hui Teh, Sock Hoai Chan, Cedric Ng Chuan Young, Richard Quek, Sittampalam Kesavan, Melissa Ching Ching Teo, F. Chin, Khee Chee Soo, Shao-Tzu Li, Gek San Tan

المساهمون: Lee Kong Chian School of Medicine (LKCMedicine)

المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Scientific Reports

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Adolescent, DNA Repair, DNA repair, lcsh:Medicine, Biology, Article, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Germline mutation, Biomarkers, Tumor, medicine, Genetic predisposition, Humans, Genetic Predisposition to Disease, Science::Medicine [DRNTU], lcsh:Science, Germ-Line Mutation, Genetic testing, Genetics, Multidisciplinary, medicine.diagnostic_test, lcsh:R, Computational Biology, Cancer, Sarcoma, Oncogenes, Sequence Analysis, DNA, Middle Aged, medicine.disease, Germline Mutations, MSH6, 030104 developmental biology, 030220 oncology & carcinogenesis, Female, lcsh:Q, ERCC4, DNA Damage

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a402f2c29a3240027334ea9aa3e6fa3
https://doi.org/10.1038/s41598-017-10333-x

المؤلفون: Masafumi Muratani, Niantao Deng, Wen Fong Ooi, Suling Joyce Lin, Manjie Xing, Chang Xu, Aditi Qamra, Su Ting Tay, Simeen Malik, Jeanie Wu, Ming Hui Lee, Shenli Zhang, Luke Lin Chuen Tan

المصدر: Nature, Nature Communications. 5(1):1-14

الإتاحة: https://ideas.repec.org/a/nat/natcom/v5y2014i1d10.1038_ncomms5361.html

المؤلفون: Iain Beehuat Tan, Patrick Tan, Kalpana Ramnarayanan, Steve Rozen, Alexander Yf Chung, Choon Leong Tang, Chung Yip Chan, Lezhava Alexander, Rachel Ten, Axel M. Hillmer, Bin Tean Teh, Dennis Koh, Sarah Boonhsui Ng, Simeen Malik, Clarinda Chua, Su Ting Tay, John R. McPherson, Joanna Tan, Dan Liang Ho, Kiat Hon Lim, Su Yan, Chew Min Hoe, Niranjan Nagarajan, Cheryl Xueli Chan, Yuka Suzuki, Brian K. P. Goh

المصدر: Genome Biology

مصطلحات موضوعية: Colorectal cancer, Molecular Sequence Data, Population, Single-nucleotide polymorphism, Allelic Imbalance, Biology, Bioinformatics, Germline, Metastasis, Neoplasms, Multiple Primary, Gene Frequency, medicine, Humans, Allele, education, Allele frequency, Alleles, education.field_of_study, Base Sequence, Genome, Human, Research, Liver Neoplasms, Computational Biology, High-Throughput Nucleotide Sequencing, medicine.disease, Primary tumor, Mutation, Disease Progression, Cancer research, Colorectal Neoplasms, Algorithms, Genes, Neoplasm

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03afbb448a7a854f32f7f4ff6108229d
https://doi.org/10.1186/s13059-015-0589-1

المؤلفون: Toshinori Hinoue, Daniel J. Weisenberger, Christopher P.E. Lange, Hui Shen, Hyang-Min Byun, David Van Den Berg, Simeen Malik, Fei Pan, Houtan Noushmehr, Cornelis M. van Dijk, Rob A.E.M. Tollenaar, Peter W. Laird

المصدر: Genome Research, 22(2), 271-282

مصطلحات موضوعية: Colorectal cancer, Genome-wide association study, Biology, medicine.disease_cause, Proto-Oncogene Proteins p21(ras), Proto-Oncogene Proteins, Biomarkers, Tumor, Genetics, medicine, Cluster Analysis, Humans, Gene Silencing, Epigenetics, Promoter Regions, Genetic, neoplasms, Genetics (clinical), Regulation of gene expression, Mutation, CpG Island Methylator Phenotype, Research, DNA Methylation, medicine.disease, digestive system diseases, Gene Expression Regulation, Neoplastic, CpG site, DNA methylation, ras Proteins, Cancer research, CpG Islands, Colorectal Neoplasms, Genome-Wide Association Study

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44595d977be75ef037ec6175b316e9c3
http://hdl.handle.net/1887/97965

المؤلفون: Sabine Cerny-Reiterer, Peter Valent, Asif Javed, Wah Heng Lee, Steve Rozen, Win Kin Sung, Wee Joo Chng, Axel M. Hillmer, Thushangi N. Pathiraja, Naoto Takahashi, Peiyong Guan, Kris C. Wood, Xin Xuan Sheila Soh, S. Tiong Ong, Audrey S.M. Teo, Tun Kiat Ko, Charles Chuah, Patrick Tan, Ravi Bhatia, Chandana Tennakoon, Willie Yu, Peter S. Winter, Joanna H.J. Tan, King Pan Ng, Qiangze Hoi, Pauline Ng, Simeen Malik

المصدر: Blood. 126:2764-2764

مصطلحات موضوعية: Genetics, education.field_of_study, Candidate gene, Myeloid, Immunology, Population, Decitabine, Cell Biology, Hematology, Epigenome, Biology, Biochemistry, Transcriptome, medicine.anatomical_structure, medicine, Epigenetics, education, medicine.drug, Epigenomics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c4f82279a99033345aba1be5b48309eb
https://doi.org/10.1182/blood.v126.23.2764.2764

المؤلفون: Naoto Takahashi, S. Tiong Ong, Win Kin Sung, Wee Joo Chng, Joanna H.J. Tan, Audrey S.M. Teo, Simeen Malik, Thushangi N. Pathiraja, Peiyong Guan, Patrick Tan, Pauline Ng, Xin Xuan Sheila Soh, Qiangze Hoi, Ravi Bhatia, Asif Javed, Wah Heng Lee, Axel M. Hillmer, Tun Kiat Ko, Chandana Tennakoon, King Pan Ng, Charles Chuah

المصدر: Blood. 126:3737-3737

مصطلحات موضوعية: Genome instability, Genetics, Candidate gene, Mutation, Immunology, Cell Biology, Hematology, Epigenome, Biology, medicine.disease_cause, Biochemistry, Transcriptome, DNA methylation, medicine, Epigenetics, Epigenomics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bb84d58e0189ceae21260409a0e2ca9f
https://doi.org/10.1182/blood.v126.23.3737.3737

المؤلفون: Isere Kuiatse, Anna Tsimelzon, ZaWaunyka Lazard, Adam S. Potter, Hee Tae Kim, Simeen Malik, Adrian V. Lee, Angelo J. Casa, Chad J. Creighton, Steffi Oesterreich, Susan G. Hilsenbeck, PH Brown

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, medicine.drug_class, Pyridones, medicine.medical_treatment, Down-Regulation, Breast Neoplasms, Kaplan-Meier Estimate, Biology, Article, Disease-Free Survival, Receptor, IGF Type 1, Insulin-like growth factor, Breast cancer, Internal medicine, Cell Line, Tumor, medicine, Biomarkers, Tumor, Humans, Genes, Tumor Suppressor, Insulin-Like Growth Factor I, Psychological repression, Fulvestrant, Adaptor Proteins, Signal Transducing, Cell Proliferation, Oligonucleotide Array Sequence Analysis, Estradiol, Microarray analysis techniques, Kinase, Gene Expression Profiling, Estrogen Receptor alpha, medicine.disease, Prognosis, Gene Expression Regulation, Neoplastic, Endocrinology, Oncology, Estrogen, Cancer research, Benzimidazoles, Female, Estrogen receptor alpha, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ff041368703ece3b1637834635bdab
https://europepmc.org/articles/PMC3936881/

المؤلفون: Matjaž Rokavec, Steffi Oesterreich, Hiltrud Brauch, Gokul M. Das, Wensheng Liu, Ina S. Abele, Werner Schroth, Simeen Malik, Peter Fritz, Santhi D. Konduri, Reiner Hoppe, Stephanie Hammerich-Hille, Heiko van der Kuip, Benny Abraham Kaipparettu

مصطلحات موضوعية: Cancer Research, Chromatin Immunoprecipitation, Transcription, Genetic, medicine.drug_class, Down-Regulation, Breast Neoplasms, Electrophoretic Mobility Shift Assay, Biology, Hydroxamic Acids, Polymerase Chain Reaction, Article, Cell Line, Tumor, medicine, Humans, Electrophoretic mobility shift assay, RNA, Messenger, Enzyme Inhibitors, Promoter Regions, Genetic, skin and connective tissue diseases, Psychological repression, Thyroid hormone receptor, Estrogen Receptor alpha, CD24 Antigen, Estrogens, Gene Expression Regulation, Neoplastic, Histone Deacetylase Inhibitors, Trichostatin A, Oncology, Estrogen, Cancer research, Female, Histone deacetylase, LCOR, Chromatin immunoprecipitation, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09b1609a7e4bfcbddb5e14ee0947f32
https://europepmc.org/articles/PMC2587263/