المؤلفون: Simelane, MBC, Lawal, OA, Djarova, TG, Musabayane, CT, Singh, M, Opoku, AR

المصدر: African Journal of Traditional, Complementary and Alternative Medicines; Vol 9, No 4 (2012); 561-573

مصطلحات موضوعية: Gunnera perpensa, Gunneraceae, cytotoxicity, lactation, muscle contractility

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=78975075580c::5515dd0e892f748350688b10d6976939
https://www.ajol.info/index.php/ajtcam/article/view/81724

المؤلفون: Nndwammbi AAT; Department of Biochemistry, Faculty of Science, University of Johannesburg, Johannesburg, 2006, South Africa., Dongola TH; Department of Biochemistry & Microbiology, University of Venda, Thohoyandou, South Africa., Shonhai A; Department of Biochemistry & Microbiology, University of Venda, Thohoyandou, South Africa., Mokoena F; Department of Biochemistry, Faculty of Natural and Agricultural Science, North West University, Mmabatho, South Africa., Pooe OJ; School of Life Sciences, University of KwaZulu-Natal, Durban, Westville, 4000, South Africa., Simelane MBC; Department of Biochemistry, Faculty of Science, University of Johannesburg, Johannesburg, 2006, South Africa. msimelane@uj.ac.za.

المصدر: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2024 Jul; Vol. 397 (7), pp. 5179-5192. Date of Electronic Publication: 2024 Jan 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Plasmodium falciparum*/drug effects , Ursolic Acid* , HSP90 Heat-Shock Proteins*/metabolism , Antimalarials*/pharmacology , Molecular Docking Simulation* , Triterpenes*/pharmacology , Triterpenes*/chemistry, Molecular Dynamics Simulation ; Protein Binding ; Protozoan Proteins/metabolism ; Acetates/chemistry ; Acetates/pharmacology ; Surface Plasmon Resonance

المؤلفون: Erhabor OG; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria., Obochi P; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria., Isah MB; Department of Biochemistry, Umaru Musa Yar'adua University, Katsina, Nigeria., Usman MA; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria., Umar IA; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria., Simelane MBC; Department of Biochemistry, University of Johannesburg, Johannesburg, South Africa., Shuaibu MN; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria., Islam MS; School of Life Sciences, University of KwaZulu-Natal, Durban, South Africa., Ibrahim MA; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria.

المصدر: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2024 Jun 24; Vol. 15, pp. 1289653. Date of Electronic Publication: 2024 Jun 24 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE

مواضيع طبية MeSH: Neuraminidase*/metabolism , Sialyltransferases*/metabolism , N-Acetylneuraminic Acid*/metabolism , Diabetes Mellitus, Type 2*/metabolism , Diabetes Mellitus, Experimental*/metabolism , Diabetes Mellitus, Type 1*/metabolism , Diabetes Mellitus, Type 1*/blood, Animals ; Rats ; Male ; Liver/metabolism ; Liver/enzymology ; Rats, Wistar ; Pancreas/metabolism ; Pancreas/enzymology ; Kidney/metabolism ; Muscle, Skeletal/metabolism

المؤلفون: Raphela-Choma PP; Department of Biochemistry, University of Johannesburg, Corner Kingsway and University Road, Auckland Park, Johannesburg, 2092, South Africa. portiapheladi22@gmail.com., Lukhwareni R; Department of Biochemistry, University of Johannesburg, Corner Kingsway and University Road, Auckland Park, Johannesburg, 2092, South Africa., Simelane MBC; Department of Biochemistry, University of Johannesburg, Corner Kingsway and University Road, Auckland Park, Johannesburg, 2092, South Africa., Motadi LR; Department of Biochemistry, University of Johannesburg, Corner Kingsway and University Road, Auckland Park, Johannesburg, 2092, South Africa., Choene MS; Department of Biochemistry, University of Johannesburg, Corner Kingsway and University Road, Auckland Park, Johannesburg, 2092, South Africa.

المصدر: Scientific reports [Sci Rep] 2024 Jun 14; Vol. 14 (1), pp. 13744. Date of Electronic Publication: 2024 Jun 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Xenograft Model Antitumor Assays* , Breast Neoplasms*/drug therapy , Breast Neoplasms*/pathology , Apoptosis*/drug effects , Mice, Nude*, Animals ; Humans ; Female ; Mice ; MCF-7 Cells ; Antineoplastic Agents/pharmacology ; Cell Proliferation/drug effects

المؤلفون: Buthelezi MN; Department of Biochemistry, Faculty of Science, University of Johannesburg, Auckland Park Kingsway Campus, Johannesburg, South Africa., Tshililo VG; Department of Biochemistry, Faculty of Science, University of Johannesburg, Auckland Park Kingsway Campus, Johannesburg, South Africa., Kappo AP; Department of Biochemistry, Faculty of Science, University of Johannesburg, Auckland Park Kingsway Campus, Johannesburg, South Africa., Simelane MBC; Department of Biochemistry, Faculty of Science, University of Johannesburg, Auckland Park Kingsway Campus, Johannesburg, South Africa. msimelane@uj.ac.za.

المصدر: Malaria journal [Malar J] 2024 May 11; Vol. 23 (1), pp. 141. Date of Electronic Publication: 2024 May 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875 (Electronic) Linking ISSN: 14752875 NLM ISO Abbreviation: Malar J Subsets: MEDLINE

مواضيع طبية MeSH: Antimalarials*/pharmacology , Antimalarials*/chemistry , Ziziphus*/chemistry , Plasmodium falciparum*/drug effects , Plant Extracts*/pharmacology , Plant Extracts*/chemistry , Phytochemicals*/pharmacology , Phytochemicals*/chemistry , Phytochemicals*/isolation & purification, Drug Discovery

المؤلفون: Abdulrashid NI; Department of Biochemistry, Ahmadu Bello University, Zaria 810241, Nigeria., Aminu S; Department of Biochemistry, Ahmadu Bello University, Zaria 810241, Nigeria., Adamu RM; Department of Biotechnology, School of Engineering and Technology, Sharda University, Greater Noida 201310, India., Tajuddeen N; Department of Chemistry, Ahmadu Bello University, Zaria 810241, Nigeria., Isah MB; Department of Biochemistry, Umaru Musa Yar'adua University, Katsina 820241, Nigeria., Jatau ID; Department of Veterinary Parasitology and Entomology, Ahmadu Bello University, Zaria 810241, Nigeria., Aliyu AB; Department of Chemistry, Ahmadu Bello University, Zaria 810241, Nigeria., Simelane MBC; Department of Biochemistry, University of Johannesburg, Johannesburg 2001, South Africa., Onyike E; Department of Biochemistry, Ahmadu Bello University, Zaria 810241, Nigeria., Ibrahim MA; Department of Biochemistry, Ahmadu Bello University, Zaria 810241, Nigeria.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2022 Jan 12; Vol. 27 (2). Date of Electronic Publication: 2022 Jan 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

مواضيع طبية MeSH: Phloroglucinol/*pharmacology , Trypanocidal Agents/*pharmacology , Trypanosoma congolense/*drug effects , Trypanosomiasis, African/*drug therapy, Anemia/complications ; Anemia/drug therapy ; Animals ; Female ; Kidney/drug effects ; Kidney/parasitology ; Kidney/pathology ; Liver/drug effects ; Liver/parasitology ; Liver/pathology ; Male ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Neuraminidase/antagonists & inhibitors ; Neuraminidase/chemistry ; Organ Size/drug effects ; Phloroglucinol/chemistry ; Phloroglucinol/therapeutic use ; Phospholipases A2/chemistry ; Phospholipases A2/metabolism ; Rats, Wistar ; Survival Analysis ; Trypanocidal Agents/chemistry ; Trypanocidal Agents/therapeutic use ; Trypanosoma congolense/parasitology ; Trypanosomiasis, African/blood ; Trypanosomiasis, African/complications ; Trypanosomiasis, African/parasitology ; Rats

المؤلفون: Zuma LK; Discipline of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Durban, South Africa., Gasa NL; Discipline of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Durban, South Africa., Mazibuko X; Discipline of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Durban, South Africa., Simelane MBC; Department of Biochemistry, University of Johannesburg, Auckland Park, South Africa., Pillay P; Chemicals Cluster, Council for Scientific and Industrial Research (CSIR), Pretoria, South Africa., Kwezi L; Chemicals Cluster, Council for Scientific and Industrial Research (CSIR), Pretoria, South Africa., Tsekoa T; Chemicals Cluster, Council for Scientific and Industrial Research (CSIR), Pretoria, South Africa., Pooe OJ; Discipline of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Durban, South Africa.

المصدر: Protein and peptide letters [Protein Pept Lett] 2022; Vol. 29 (6), pp. 505-513.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 9441434 Publication Model: Print Cited Medium: Internet ISSN: 1875-5305 (Electronic) Linking ISSN: 09298665 NLM ISO Abbreviation: Protein Pept Lett Subsets: MEDLINE

مواضيع طبية MeSH: DNA Ligases* , Polyethylene Glycols*/chemistry, DNA, Recombinant ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Proteins/chemistry

المؤلفون: Salomane N; Department of Biochemistry, Faculty of Science, University of Johannesburg, Johannesburg, 2006, South Africa., Pooe OJ; Discipline of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville, Durban, 4000, South Africa., Simelane MBC; Department of Biochemistry, Faculty of Science, University of Johannesburg, Johannesburg, 2006, South Africa. msimelane@uj.ac.za.

المصدر: Cell stress & chaperones [Cell Stress Chaperones] 2021 Jul; Vol. 26 (4), pp. 685-693. Date of Electronic Publication: 2021 May 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9610925 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1466-1268 (Electronic) Linking ISSN: 13558145 NLM ISO Abbreviation: Cell Stress Chaperones Subsets: MEDLINE

مواضيع طبية MeSH: HSP70 Heat-Shock Proteins/*drug effects , HSP70 Heat-Shock Proteins/*metabolism , Molecular Chaperones/*metabolism , Plasmodium falciparum/*metabolism , Triterpenes/*pharmacology, Adenosine Triphosphatases/metabolism ; Antimalarials/chemistry ; Antimalarials/metabolism ; Antimalarials/pharmacology ; Escherichia coli/metabolism ; Plasmodium falciparum/drug effects ; Prospective Studies ; Recombinant Proteins/chemistry ; Recombinant Proteins/metabolism ; Ursolic Acid

المؤلفون: Opoku F; Department of Chemical Sciences, University of Johannesburg, P.O. Box 17011, Doornfontein Campus, Johannesburg 2028, South Africa., Govender PP; Department of Chemical Sciences, University of Johannesburg, P.O. Box 17011, Doornfontein Campus, Johannesburg 2028, South Africa., Pooe OJ; Discipline of Biochemistry, School of Life Science, University of KwaZulu-Natal, Westville 4000, South Africa., Simelane MBC; Department of Biochemistry, Faculty of Science, University of Johannesburg, Johannesburg 2006, South Africa.

المصدر: Biomolecules [Biomolecules] 2019 Dec 11; Vol. 9 (12). Date of Electronic Publication: 2019 Dec 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

مواضيع طبية MeSH: Antimalarials/*pharmacology , Enzyme Inhibitors/*pharmacology , Pentosyltransferases/*antagonists & inhibitors , Plasmodium falciparum/*drug effects, Acetates/chemistry ; Acetates/pharmacology ; Antimalarials/chemistry ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/chemistry ; Ligands ; Models, Molecular ; Parasitic Sensitivity Tests ; Plasmodium falciparum/enzymology ; Polycyclic Sesquiterpenes/chemistry ; Polycyclic Sesquiterpenes/pharmacology ; Structure-Activity Relationship ; Triterpenes/chemistry ; Triterpenes/pharmacology ; Ursolic Acid

المؤلفون: Msomi NZ; School of Life Sciences, University of KwaZulu-Natal, Durban, Westville 4000, South Africa. ntokozomsomi0@gmail.com., Shode FO; Department of Biotechnology and Food Technology, Durban University of Technology, P.O. Box 1334, Durban 4000, South Africa. francisshode@gmail.com., Pooe OJ; School of Life Sciences, University of KwaZulu-Natal, Durban, Westville 4000, South Africa. PooeO@ukzn.ac.za., Mazibuko-Mbeje S; Biomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg 7505, South Africa. Sithandiwe.Mazibuko@mrc.ac.za.; Division of Medical Physiology, Faculty of Health Sciences, Stellenbosch University, Tygerberg 7505, South Africa. Sithandiwe.Mazibuko@mrc.ac.za., Simelane MBC; Department of Biochemistry, Faculty of Science, University of Johannesburg, Auckland Park 2092, Johannesburg 2006, South Africa. msimelane@uj.ac.za.

المصدر: Biomolecules [Biomolecules] 2019 Sep 22; Vol. 9 (10). Date of Electronic Publication: 2019 Sep 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

مواضيع طبية MeSH: Glucose/*metabolism , Magnoliopsida/*chemistry , Myoblasts, Skeletal/*cytology , Polycyclic Sesquiterpenes/*pharmacology, AMP-Activated Protein Kinases/metabolism ; Animals ; Cell Line ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Myoblasts, Skeletal/drug effects ; Myoblasts, Skeletal/metabolism ; Plant Bark/chemistry ; Plant Extracts/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; Rats