المؤلفون: Zheng X; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA 92037, USA., Wu B; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA 92037, USA., Liu Y; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA 92037, USA., Simmons SK; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Kim K; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Clarke GS; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA 92037, USA., Ashiq A; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA 92037, USA., Park J; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA 92037, USA., Li J; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA 92037, USA., Wang Z; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA 92037, USA., Tong L; Center for Neural Circuit Mapping, Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, CA 92617, USA., Wang Q; Center for Neural Circuit Mapping, Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, CA 92617, USA., Rajamani KT; Appel Alzheimer's Disease Research Institute, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10021, USA., Muñoz-Castañeda R; Appel Alzheimer's Disease Research Institute, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10021, USA., Mu S; Appel Alzheimer's Disease Research Institute, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10021, USA., Qi T; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA 92037, USA., Zhang Y; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA 92037, USA., Ngiam ZC; Center for Advanced Biomedical Sciences, Waseda University, Tokyo 162-8480, Japan., Ohte N; Center for Advanced Biomedical Sciences, Waseda University, Tokyo 162-8480, Japan., Hanashima C; Center for Advanced Biomedical Sciences, Waseda University, Tokyo 162-8480, Japan., Wu Z; Appel Alzheimer's Disease Research Institute, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10021, USA., Xu X; Center for Neural Circuit Mapping, Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, CA 92617, USA., Levin JZ; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Jin X; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA 92037, USA. Electronic address: xinjin@scripps.edu.

المصدر: Cell [Cell] 2024 Jun 20; Vol. 187 (13), pp. 3236-3248.e21. Date of Electronic Publication: 2024 May 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: Gene Regulatory Networks* , Single-Cell Analysis*/methods, Animals ; Female ; Humans ; Mice ; Cerebral Cortex/metabolism ; Cerebral Cortex/cytology ; CRISPR-Cas Systems/genetics ; Dependovirus/genetics ; Forkhead Transcription Factors/metabolism ; Forkhead Transcription Factors/genetics ; Genetic Vectors/metabolism ; Mice, Inbred C57BL ; Nerve Tissue Proteins/metabolism ; Nerve Tissue Proteins/genetics ; Neurons/metabolism ; Neurons/cytology ; Transcriptome/genetics ; Cell Line ; Transcription, Genetic

المؤلفون: Farsi Z; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address: zfarsi@broadinstitute.org., Nicolella A; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Simmons SK; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Aryal S; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Shepard N; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Brenner K; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lin S; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Herzog L; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Moran SP; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Stalnaker KJ; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Shin W; Center for Synaptic Brain Dysfunctions, Institute for Basic Science, Daejeon, South Korea., Gazestani V; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Song BJ; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Bonanno K; Proteomics Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Keshishian H; Proteomics Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Carr SA; Proteomics Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Pan JQ; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Macosko EZ; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA; Massachusetts General Hospital, Department of Psychiatry, Boston, MA, USA., Datta SR; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Dejanovic B; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kim E; Center for Synaptic Brain Dysfunctions, Institute for Basic Science, Daejeon, South Korea; Department of Biological Sciences, Korea Advanced Institute for Science and Technology, Daejeon, South Korea., Levin JZ; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Sheng M; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address: msheng@broadinstitute.org.

المصدر: Neuron [Neuron] 2023 Nov 01; Vol. 111 (21), pp. 3378-3396.e9. Date of Electronic Publication: 2023 Aug 31.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE

مواضيع طبية MeSH: Dopamine*/metabolism , Proteomics* , Receptors, N-Methyl-D-Aspartate*/genetics, Animals ; Mice ; Brain/metabolism ; Neuroglia/metabolism ; Neurons/metabolism ; Prefrontal Cortex/metabolism ; Disease Models, Animal

المؤلفون: Zheng X; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA, USA., Wu B; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA, USA., Liu Y; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA, USA., Simmons SK; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kim K; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Clarke GS; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA, USA., Ashiq A; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA, USA., Park J; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA, USA., Wang Z; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA, USA., Tong L; Center for Neural Circuit Mapping, Department of Anatomy and Neurobiology, University of California, Irvine, CA, USA., Wang Q; Center for Neural Circuit Mapping, Department of Anatomy and Neurobiology, University of California, Irvine, CA, USA., Xu X; Center for Neural Circuit Mapping, Department of Anatomy and Neurobiology, University of California, Irvine, CA, USA., Levin JZ; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Jin X; Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Sep 18. Date of Electronic Publication: 2023 Sep 18.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Ximerakis M; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA. methodiosximerakis@gmail.com.; Harvard Stem Cell Institute, Cambridge, MA, USA. methodiosximerakis@gmail.com.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. methodiosximerakis@gmail.com., Holton KM; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Giadone RM; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA., Ozek C; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA., Saxena M; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA., Santiago S; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA., Adiconis X; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Dionne D; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Nguyen L; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Shah KM; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA., Goldstein JM; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA., Gasperini C; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA., Gampierakis IA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA., Lipnick SL; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Simmons SK; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Buchanan SM; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA., Wagers AJ; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA.; Joslin Diabetes Center, Boston, MA, USA.; Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA., Regev A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Howard Hughes Medical Institute, Koch Institute of Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Levin JZ; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Rubin LL; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA. lee_rubin@harvard.edu.; Harvard Stem Cell Institute, Cambridge, MA, USA. lee_rubin@harvard.edu.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. lee_rubin@harvard.edu.

المصدر: Nature aging [Nat Aging] 2023 Mar; Vol. 3 (3), pp. 327-345. Date of Electronic Publication: 2023 Mar 09.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group US Country of Publication: United States NLM ID: 101773306 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-8465 (Electronic) Linking ISSN: 26628465 NLM ISO Abbreviation: Nat Aging Subsets: MEDLINE

مواضيع طبية MeSH: Transcriptome*/genetics , Endothelial Cells*, Animals ; Mice ; Aging/genetics ; Parabiosis ; Brain

المؤلفون: Simmons SK; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lithwick-Yanai G; Ultima Genomics, Newark, CA, USA., Adiconis X; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Oberstrass F; Ultima Genomics, Newark, CA, USA., Iremadze N; Ultima Genomics, Newark, CA, USA., Geiger-Schuller K; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Genentech, South San Francisco, CA, USA., Thakore PI; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Genentech, South San Francisco, CA, USA., Frangieh CJ; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA, USA., Barad O; Ultima Genomics, Newark, CA, USA., Almogy G; Ultima Genomics, Newark, CA, USA., Rozenblatt-Rosen O; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Genentech, South San Francisco, CA, USA., Regev A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biology, MIT, Cambridge, MA, USA.; Genentech, South San Francisco, CA, USA., Lipson D; Ultima Genomics, Newark, CA, USA., Levin JZ; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA. jlevin@broadinstitute.org.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. jlevin@broadinstitute.org.

المصدر: Nature biotechnology [Nat Biotechnol] 2023 Feb; Vol. 41 (2), pp. 204-211. Date of Electronic Publication: 2022 Sep 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Profiling*/methods , Leukocytes, Mononuclear*, Humans ; Sequence Analysis, RNA/methods ; Single-Cell Gene Expression Analysis ; Single-Cell Analysis/methods ; Nucleotides

المؤلفون: Paulsen B; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Velasco S; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA. silvia.velasco@mcri.edu.au.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. silvia.velasco@mcri.edu.au.; Murdoch Children's Research Institute, The Royal Children's Hospital, Parkville, Victoria, Australia. silvia.velasco@mcri.edu.au., Kedaigle AJ; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Pigoni M; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Quadrato G; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Deo AJ; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Psychiatry, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Psychiatry, Rutgers-Robert Wood Johnson Medical School, Piscataway, NJ, USA.; Rutgers University Behavioral Health Care, Piscataway, NJ, USA., Adiconis X; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Uzquiano A; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Sartore R; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Yang SM; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Simmons SK; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Symvoulidis P; MIT Center for Neurobiological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA., Kim K; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Tsafou K; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Podury A; MIT Center for Neurobiological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Harvard-MIT Health Sciences & Technology Program (HST), Harvard Medical School, Boston, MA, USA., Abbate C; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Tucewicz A; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Smith SN; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Albanese A; Institute for Medical Engineering and Science, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA., Barrett L; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Sanjana NE; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; New York Genome Center, New York, NY, USA.; Department of Biology, New York University, New York, NY, USA., Shi X; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Chung K; Institute for Medical Engineering and Science, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Picower Institute for Learning and Memory, Departments of Chemical Engineering and Brain and Cognitive Sciences, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; New York Genome Center, New York, NY, USA., Lage K; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Surgery and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., Boyden ES; MIT Center for Neurobiological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Harvard-MIT Health Sciences & Technology Program (HST), Harvard Medical School, Boston, MA, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Howard Hughes Medical Institute, MIT, Cambridge, MA, USA.; Department of Brain of Cognitive Sciences, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Department of Media Arts and Sciences, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA., Regev A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Genentech, South San Francisco, CA, USA., Levin JZ; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Arlotta P; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA. paola_arlotta@harvard.edu.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. paola_arlotta@harvard.edu.

المصدر: Nature [Nature] 2022 Feb; Vol. 602 (7896), pp. 268-273. Date of Electronic Publication: 2022 Feb 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Autism Spectrum Disorder*/genetics , Autism Spectrum Disorder*/metabolism , Autism Spectrum Disorder*/pathology , Genetic Predisposition to Disease* , Neurons*/classification , Neurons*/metabolism , Neurons*/pathology, Cerebral Cortex/cytology ; DNA-Binding Proteins/genetics ; GABAergic Neurons/metabolism ; GABAergic Neurons/pathology ; Histone-Lysine N-Methyltransferase/genetics ; Humans ; Organoids/cytology ; Proteomics ; RNA-Seq ; Single-Cell Analysis ; Transcription Factors/genetics

المؤلفون: Sorek M; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel.; The Edmond and Lily Center for Brain Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel., Oweis W; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel., Nissim-Rafinia M; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel., Maman M; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel., Simon S; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel., Hession CC; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Adiconis X; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Simmons SK; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Sanjana NE; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; New York Genome Center and Department of Biology, New York University, New York, NY, USA., Shi X; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lu C; New York Genome Center and Department of Biology, New York University, New York, NY, USA., Pan JQ; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Xu X; Department of Neurology and Stroke Center, The First Affiliated Hospital, Jinan University, 613 Huangpu Avenue West, Guangzhou, 510632, Guangdong, China.; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore., Pouladi MA; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore.; Department of Physiology, National University of Singapore, Singapore, 117597, Singapore.; British Columbia Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, V5Z 4H4, Canada., Ellerby LM; Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA, 94945, USA., Zhang F; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Levin JZ; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Meshorer E; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel. eran.meshorer@mail.huji.ac.il.; The Edmond and Lily Center for Brain Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel. eran.meshorer@mail.huji.ac.il.

المصدر: Genome biology [Genome Biol] 2021 Mar 04; Vol. 22 (1), pp. 73. Date of Electronic Publication: 2021 Mar 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation* , Genetic Heterogeneity* , Genetic Predisposition to Disease* , Models, Biological*, Neurodegenerative Diseases/*etiology , Pluripotent Stem Cells/*metabolism, Adult ; Gene Expression Profiling ; Gene Regulatory Networks ; Genetic Background ; High-Throughput Nucleotide Sequencing ; Humans ; Mutation ; RNA-Seq ; Single-Cell Analysis/methods

المؤلفون: Jin X; Society of Fellows, Harvard University, Cambridge, MA, USA. xinjin@fas.harvard.edu aregev@broadinstitute.org zhang@broadinstitute.org paola_arlotta@harvard.edu.; Department of Stem Cell and Regenerative Biology, Harvard University, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute of Brain Science, Department of Brain and Cognitive Science, Department of Biological Engineering, Massachussetts Institute of Technology (MIT), Cambridge, MA, USA., Simmons SK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Guo A; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Shetty AS; Department of Stem Cell and Regenerative Biology, Harvard University, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ko M; Department of Stem Cell and Regenerative Biology, Harvard University, MA, USA., Nguyen L; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Jokhi V; Department of Stem Cell and Regenerative Biology, Harvard University, MA, USA., Robinson E; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA., Oyler P; Department of Stem Cell and Regenerative Biology, Harvard University, MA, USA., Curry N; Department of Stem Cell and Regenerative Biology, Harvard University, MA, USA., Deangeli G; Department of Stem Cell and Regenerative Biology, Harvard University, MA, USA., Lodato S; Department of Biomedical Sciences and Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Humanitas Clinical and Research Center, Humanitas University, Milan, Italy., Levin JZ; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Regev A; Broad Institute of MIT and Harvard, Cambridge, MA, USA. xinjin@fas.harvard.edu aregev@broadinstitute.org zhang@broadinstitute.org paola_arlotta@harvard.edu.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Koch Institute of Integrative Cancer Research, Department of Biology, MIT, Cambridge, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Zhang F; Broad Institute of MIT and Harvard, Cambridge, MA, USA. xinjin@fas.harvard.edu aregev@broadinstitute.org zhang@broadinstitute.org paola_arlotta@harvard.edu.; McGovern Institute of Brain Science, Department of Brain and Cognitive Science, Department of Biological Engineering, Massachussetts Institute of Technology (MIT), Cambridge, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Arlotta P; Department of Stem Cell and Regenerative Biology, Harvard University, MA, USA. xinjin@fas.harvard.edu aregev@broadinstitute.org zhang@broadinstitute.org paola_arlotta@harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.

المصدر: Science (New York, N.Y.) [Science] 2020 Nov 27; Vol. 370 (6520).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Autistic Disorder/*genetics , Autistic Disorder/*pathology , Brain/*abnormalities , Neuroglia/*pathology , Neurons/*pathology, Animals ; Ankyrins/genetics ; Ankyrins/metabolism ; CRISPR-Cas Systems ; DNA-Binding Proteins/genetics ; Frameshift Mutation ; Gene Expression Profiling ; Genetic Loci ; Humans ; Mice ; Neuroglia/metabolism ; Neurons/metabolism ; Repressor Proteins/genetics ; Risk ; Transcription Factors/genetics

المؤلفون: Li Y; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Center for Synthetic and Systems Biology, Tsinghua University, Beijing, P. R. China.; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Lopez-Huerta VG; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.; Institute of Cellular Physiology, National Autonomous University of Mexico, Mexico City, Mexico., Adiconis X; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Levandowski K; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Choi S; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Simmons SK; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Arias-Garcia MA; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.; Faculty of Psychology, National Autonomous University of Mexico, Mexico City, Mexico., Guo B; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Yao AY; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Blosser TR; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Wimmer RD; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Aida T; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Atamian A; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Naik T; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Sun X; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.; College of Computer Science and Technology, Zhejiang University, Hangzhou, P. R. China., Bi D; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Malhotra D; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Hession CC; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Shema R; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Gomes M; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.; University of Coimbra, Center for Neuroscience and Cell Biology, Coimbra, Portugal.; University of Coimbra, Institute for Interdisciplinary Research, Coimbra, Portugal., Li T; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Hwang E; Center for Neuroscience, Korea Institute of Science and Technology, Seoul, South Korea., Krol A; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Kowalczyk M; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Peça J; University of Coimbra, Center for Neuroscience and Cell Biology, Coimbra, Portugal.; University of Coimbra, Institute for Interdisciplinary Research, Coimbra, Portugal.; University of Coimbra, Department of Life Sciences, Coimbra, Portugal., Pan G; College of Computer Science and Technology, Zhejiang University, Hangzhou, P. R. China., Halassa MM; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Levin JZ; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. jlevin@broadinstitute.org.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA. jlevin@broadinstitute.org., Fu Z; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. zfu@broadinstitute.org.; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA. zfu@broadinstitute.org., Feng G; The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. fengg@mit.edu.; McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA. fengg@mit.edu.

المصدر: Nature [Nature] 2020 Jul; Vol. 583 (7818), pp. 819-824. Date of Electronic Publication: 2020 Jul 22.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Gene Regulatory Networks*, Thalamic Nuclei/*cytology , Thalamic Nuclei/*metabolism, Animals ; Cluster Analysis ; Female ; Gene Expression Profiling ; In Situ Hybridization, Fluorescence ; Metalloendopeptidases/metabolism ; Mice ; Neural Pathways ; Neurons/metabolism ; Osteopontin/metabolism ; Patch-Clamp Techniques ; RNA-Seq ; Single-Cell Analysis ; Sleep/genetics ; Sleep/physiology ; Thalamic Nuclei/physiology ; Transcriptome

المؤلفون: Ding J; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Adiconis X; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Simmons SK; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kowalczyk MS; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hession CC; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Marjanovic ND; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hughes TK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Medical Engineering and Science, Department of Chemistry, MIT, Cambridge, MA, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Koch Institute of Integrative Cancer Research, Cambridge, MA, USA., Wadsworth MH; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Medical Engineering and Science, Department of Chemistry, MIT, Cambridge, MA, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Koch Institute of Integrative Cancer Research, Cambridge, MA, USA., Burks T; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Nguyen LT; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kwon JYH; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Barak B; McGovern Institute for Brain Research and Department of Brain and Cognitive Sciences, MIT, Cambridge, MA, USA., Ge W; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kedaigle AJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Carroll S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Medical Engineering and Science, Department of Chemistry, MIT, Cambridge, MA, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Koch Institute of Integrative Cancer Research, Cambridge, MA, USA., Li S; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hacohen N; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Rozenblatt-Rosen O; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Shalek AK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Medical Engineering and Science, Department of Chemistry, MIT, Cambridge, MA, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Koch Institute of Integrative Cancer Research, Cambridge, MA, USA., Villani AC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Charlestown, MA, USA., Regev A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Koch Institute of Integrative Cancer Research, Cambridge, MA, USA.; Howard Hughes Medical Institute, Department of Biology, MIT, Cambridge, MA, USA., Levin JZ; Broad Institute of MIT and Harvard, Cambridge, MA, USA. jlevin@broadinstitute.org.

المصدر: Nature biotechnology [Nat Biotechnol] 2020 Jun; Vol. 38 (6), pp. 756.

نوع المنشور: Journal Article; Published Erratum

بيانات الدورية: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: PubMed not MEDLINE; MEDLINE