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1دورية أكاديمية
المؤلفون: Jörg Duschmalé, Adrian Schäublin, Erik Funder, Steffen Schmidt, Łukasz J. Kiełpiński, Helle Nymark, Klaus Jensen, Troels Koch, Martina Duschmalé, Erich Koller, Marianne Ravn Møller, Simone Schadt, Christophe Husser, Andreas Brink, Sabine Sewing, Tanja Minz, Jesper Wengel, Konrad Bleicher, Meiling Li
المصدر: Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 176-188 (2022)
مصطلحات موضوعية: MT: oligonucleotides: therapies and applications, locked nucleic acids, antisense oligonucleotides, phosphorodithioates, stereodefined phosphorodithioates, discovery strategies, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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المؤلفون: Ramona Nudischer, Sabine Sewing, Adrian Roth, Barbara M. Elcombe, Andreas Hierlemann, Nicholas Flint, Jean-Christophe Hoflack, Kasper Renggli, Lykke Pedersen, Franziska Boess, Barbara Lenz, Simone Schadt, Cristina Bertinetti-Lapatki, Larry G. Higgins, Audrey Vardy, Laurent Gand
المصدر: Toxicological Sciences. 176:329-342
مصطلحات موضوعية: 0301 basic medicine, Receptors, Steroid, Pyridines, Receptors, Cytoplasmic and Nuclear, Toxicology, Mice, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, In vivo, Constitutive androstane receptor, Animals, Humans, Constitutive Androstane Receptor, Gene knockdown, Pregnane X receptor, Chemistry, Activator (genetics), Imidazoles, Wild type, Molecular biology, Mice, Inbred C57BL, Organoids, Macaca fascicularis, 030104 developmental biology, Liver, 030220 oncology & carcinogenesis, Knockout mouse, Hepatocytes
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eae93021c5d77cd1759a967c46923ab
https://doi.org/10.1093/toxsci/kfaa076 -
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المؤلفون: Dawn Colburn, Weijiang Zhang, Dieter Roethlisberger, Enric Bertran, B. Simmons, Simone Schadt, Zsuzsanna Papai, Harper Forbes, Thomas Hartung, Christophe Husser
المصدر: Clinical Pharmacology in Drug Development. 9:496-504
مصطلحات موضوعية: medicine.medical_specialty, business.industry, Melanoma, Area under the curve, Pharmaceutical Science, Urine, medicine.disease, 030226 pharmacology & pharmacy, Gastroenterology, Bioavailability, 03 medical and health sciences, 0302 clinical medicine, MicroDose, Pharmacokinetics, 030220 oncology & carcinogenesis, Internal medicine, medicine, Pharmacology (medical), Vemurafenib, business, Adverse effect, medicine.drug
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المؤلفون: Simone Schadt, Andreas Sutter, Dieter Lang, Frank Runge, Andreas Zeller, Alessandro Brigo, Andreas Brink, Esther Vock, Jörg Wichard, Wolfgang Muster, Melanie Guérard
المصدر: Chemical Research in Toxicology. 33:10-19
مصطلحات موضوعية: Drug-Related Side Effects and Adverse Reactions, business.industry, Health authority, Context (language use), General Medicine, Toxicology, medicine.disease_cause, Risk Assessment, Drug Development, Pharmaceutical Preparations, Risk analysis (engineering), Drug development, Carcinogens, medicine, Animals, Humans, Pharmacokinetics, Amines, business, Risk assessment, Drug metabolism, Genotoxicity, Mutagens
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المؤلفون: Franz Schuler, Filipe Lopes, Simone Schadt, Adrian Roth, Roland F Staack, Wolfgang F. Richter, Roberto Villaseñor, Hubert Kettenberger, Christoph Funk, Martin R. Edelmann, Simon Hauri
المصدر: Drug Metabolism and Disposition. 47:1443-1456
مصطلحات موضوعية: Pharmacology, Drug, media_common.quotation_subject, Proteins, Pharmaceutical Science, Therapeutic protein, Computational biology, Biology, 030226 pharmacology & pharmacy, Small molecule, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, Pharmaceutical Preparations, Biotransformation, 030220 oncology & carcinogenesis, Small peptide, Animals, Humans, Drug Interactions, media_common
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7603d176988ce6d7884f289330512a40
https://doi.org/10.1124/dmd.119.088997 -
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المؤلفون: Yann Tessier, Anja Kipar, Michael J. Mihatsch, Udo Hetzel, Fernando Romero-Palomo, Andreas Brink, Erich Koller, Pawel Dzygiel, Simone Schadt, Guy Fischer, Annamaria Braendli-Baiocco, Sabine Sewing, Michael Winter, Barbara Lenz, Matthias Festag, Bernd Steinhuber, Christophe Husser
المساهمون: University of Zurich, Romero-Palomo, Fernando
المصدر: TOXICOLOGIC PATHOLOGY
مصطلحات موضوعية: Male, Acetylgalactosamine, Necrosis, Metabolite, Oligonucleotides, 10184 Institute of Veterinary Pathology, In situ hybridization, Pharmacology, Toxicology, Pathology and Forensic Medicine, 1307 Cell Biology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, 1312 Molecular Biology, medicine, Animals, Tissue Distribution, Locked nucleic acid, Molecular Biology, 030304 developmental biology, 0303 health sciences, Kidney, Chemistry, 3005 Toxicology, Cell Biology, Oligonucleotides, Antisense, Rats, 2734 Pathology and Forensic Medicine, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Toxicity, Nucleic acid, 570 Life sciences, biology, medicine.symptom, Drug metabolism
وصف الملف: application/pdf; 01926233211011615.pdf - application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd879088c7638737d2f717755fa22f7
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المؤلفون: Na Hong Qiu, Roland F Staack, Nicole A. Kratochwil, Christoph Funk, Christophe Husser, Stephen Fowler, Simone Schadt, Aynur Ekiciler
المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-6 (2019)
Scientific Reportsمصطلحات موضوعية: Proteomics, 0301 basic medicine, Dipeptidyl Peptidase 4, Recombinant Fusion Proteins, lcsh:Medicine, Context (language use), Article, 03 medical and health sciences, 0302 clinical medicine, Biotransformation, In vivo, Drug Discovery, Chymotrypsin, Humans, Lectins, C-Type, lcsh:Science, Multidisciplinary, Apolipoprotein A-I, Chemistry, Drug discovery, lcsh:R, Fusion protein, Small molecule, In vitro, 030104 developmental biology, Biochemistry, lcsh:Q, Protein Processing, Post-Translational, 030217 neurology & neurosurgery, Drug metabolism
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المؤلفون: M. Reid Groseclose, Carsten Hopf, Michael Becker, Simone Schadt, Sandra Schulz
المصدر: Current Opinion in Biotechnology. 55:51-59
مصطلحات موضوعية: 0106 biological sciences, Bioanalysis, Pharmaceutical Research, Biomedical Engineering, Bioengineering, Nanotechnology, Mass spectrometry, 01 natural sciences, Mass spectrometry imaging, 03 medical and health sciences, Imaging, Three-Dimensional, Drug Development, 010608 biotechnology, Humans, Pharmaceutical sciences, 030304 developmental biology, 0303 health sciences, Drug discovery, Chemistry, Reference Standards, Maldi msi, Biomarker (cell), Drug development, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Calibration, Biotechnology
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المؤلفون: Farah Al Qaraghuli, Ravindra Varma Alluri, Sophie M.A. Argon, Piyush Bajaj, Tashinga E. Bapiro, Abdul Basit, Andreas Brink, Tingting Cai, Jose Castro-Perez, Jae H. Chang, Eugene Chia-Te Chen, Marie Croft, Liam Evans, Raymond Evers, Robert S. Foti, Adrian J. Fretland, Christopher Gemski, Anima Ghosal, Jia Hao, Satyajeet Haridas, Simon Hauri, Nina Isoherranen, Wenying Jian, Kevin Johnson, Barry Jones, Robert S. Jones, Jan Felix Joseph, S. Cyrus Khojasteh, Yurong Lai, Hoa Le, Xiaomin Liang, Liming Liu, Filipe Lopes, Justin Q. Ly, Shuguang Ma, Roshini Markandu, Rosalinde Masereeuw, J. Eric McDuffie, Kaushik Mitra, Diana Montgomery, Alexandra L. Orton, Katie H. Owens, Axel Pähler, Maria Kristina Parr, Shefali Patel, Ichiko D. Petrie, Richard Phipps, Chandra Prakash, Bhagwat Prasad, Isabelle Ragueneau-Majlessi, Venkatesh Pilla Reddy, Ellen Riddle, Qian Ruan, Simone Schadt, Dhaval K. Shah, Julia Shanu-Wilson, Kelly MacLennan Staiger, Jonathan Steele, Manthena V.S. Varma, Matthew P. Wagoner, Naidong Weng, Stephen Wrigley, Caisheng Wu, Graeme C. Young, Jingjing Yu, Lushan Yu, Su Zeng, Haeyoung Zhang, Wanying Zhang, Andy Z.X. Zhu, Mingshe Zhu
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::32563bc881f8145ec2036a1b650e62de
https://doi.org/10.1016/b978-0-12-820018-6.09990-7 -
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المؤلفون: Axel Pähler, Andreas Brink, Simone Schadt, Filipe Lopes, Simon Hauri
مصطلحات موضوعية: Food and drug administration, Drug, Risk analysis (engineering), media_common.quotation_subject, Mist, Guidance documents, Harmonization, Business, Safety testing, media_common
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0899b7dd47955ab85e12568805884c0f
https://doi.org/10.1016/b978-0-12-820018-6.00014-4