المؤلفون: Mondleki E; Division of Clinical Pharmacology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Banda CG; Division of Clinical Pharmacology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi., Chandiwana NC; Ezintsha, University of the Witwatersrand, Johannesburg, South Africa., Sokhela S; Ezintsha, University of the Witwatersrand, Johannesburg, South Africa., Wiesner L; Division of Clinical Pharmacology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Venter F; Ezintsha, University of the Witwatersrand, Johannesburg, South Africa., Maartens G; Division of Clinical Pharmacology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa., Sinxadi PZ; Division of Clinical Pharmacology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

المصدر: Southern African journal of HIV medicine [South Afr J HIV Med] 2022 Dec 13; Vol. 23 (1), pp. 1452. Date of Electronic Publication: 2022 Dec 13 (Print Publication: 2022).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: AOSIS OpenJournals Country of Publication: South Africa NLM ID: 100965417 Publication Model: eCollection Cited Medium: Internet ISSN: 2078-6751 (Electronic) Linking ISSN: 16089693 NLM ISO Abbreviation: South Afr J HIV Med Subsets: PubMed not MEDLINE

المؤلفون: van Rensburg R; Division of Clinical Pharmacology, Department of Medicine, Stellenbosch University, Cape Town, South Africa., Nightingale S; HIV Mental Health Research Unit, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa., Brey N; Division of Neurology, Department of Medicine, Stellenbosch University, Cape Town, South Africa., Albertyn CH; Division of Neurology, Department of Medicine, Stellenbosch University, Cape Town, South Africa., Kellermann TA; Division of Clinical Pharmacology, Department of Medicine, Stellenbosch University, Cape Town, South Africa., Taljaard JJ; Division of Infectious Diseases, Department of Medicine, Stellenbosch University, Cape Town, South Africa., Esterhuizen TM; Division of Epidemiology and Biostatistics, Department of Global Health, Stellenbosch University, Cape Town, South Africaand., Sinxadi PZ; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa., Decloedt EH; Division of Clinical Pharmacology, Department of Medicine, Stellenbosch University, Cape Town, South Africa.

المصدر: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2022 Aug 31; Vol. 75 (3), pp. 399-405.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Anti-HIV Agents*/adverse effects , Arylamine N-Acetyltransferase*/genetics , HIV Infections* , Neurotoxicity Syndromes*/drug therapy , Neurotoxicity Syndromes*/genetics, Adult ; Alkynes/therapeutic use ; Benzoxazines/adverse effects ; Cyclopropanes/therapeutic use ; Cytochrome P-450 CYP2B6/genetics ; Female ; Humans ; Isoniazid/therapeutic use ; Male ; Pharmacogenetics ; Polymorphism, Single Nucleotide

المؤلفون: Sinxadi PZ; Division of Clinical Pharmacology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Khoo SH; Department of Pharmacology, University of Liverpool, Liverpool., Boffito M; Chelsea and Westminster Hospital.; Imperial College London, London, United Kingdom.

المصدر: AIDS (London, England) [AIDS] 2021 Dec 15; Vol. 35 (Suppl 2), pp. S145-S151.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 8710219 Publication Model: Print Cited Medium: Internet ISSN: 1473-5571 (Electronic) Linking ISSN: 02699370 NLM ISO Abbreviation: AIDS Subsets: MEDLINE

مواضيع طبية MeSH: Anti-HIV Agents*/adverse effects , HIV Infections*/drug therapy, Anti-Retroviral Agents/adverse effects ; Drug Interactions ; Humans ; Integrase Inhibitors

المؤلفون: Decloedt EH; Division of Clinical Pharmacology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.; Division of Clinical Pharmacology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Sinxadi PZ; Division of Clinical Pharmacology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Wiesner L; Division of Clinical Pharmacology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Joska JA; Department of Psychiatry and Mental Health, Health Sciences, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa., Haas DW; Department of Medicine, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee, United States.; Department of Internal Medicine, Meharry Medical College, Nashville, Tennessee, United States., Maartens G; Division of Clinical Pharmacology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

المصدر: Southern African journal of HIV medicine [South Afr J HIV Med] 2021 Apr 28; Vol. 22 (1), pp. 1206. Date of Electronic Publication: 2021 Apr 28 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: AOSIS OpenJournals Country of Publication: South Africa NLM ID: 100965417 Publication Model: eCollection Cited Medium: Internet ISSN: 2078-6751 (Electronic) Linking ISSN: 16089693 NLM ISO Abbreviation: South Afr J HIV Med Subsets: PubMed not MEDLINE

المؤلفون: Venter WDF; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. Electronic address: fventer@wrhi.ac.za., Moorhouse M; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Sokhela S; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Serenata C; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Akpomiemie G; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Qavi A; Faculty of Medicine, Imperial College London, London, UK., Mashabane N; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Arulappan N; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Sim JW; Faculty of Medicine, Imperial College London, London, UK., Sinxadi PZ; Division of Clinical Pharmacology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Wiesner L; Division of Clinical Pharmacology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Maharaj E; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Wallis C; BARC, Lancet Laboratories, Johannesburg, South Africa., Boyles T; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Ripin D; Clinton Health Access Initiative, Boston, MA, USA., Stacey S; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Division of Infectious Diseases, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa., Chitauri G; Division of Infectious Diseases, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa., Hill A; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK.

المصدر: The lancet. HIV [Lancet HIV] 2019 Jul; Vol. 6 (7), pp. e428-e437. Date of Electronic Publication: 2019 Jun 12.

نوع المنشور: Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101645355 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3018 (Electronic) Linking ISSN: 23523018 NLM ISO Abbreviation: Lancet HIV Subsets: MEDLINE

مواضيع طبية MeSH: Antiretroviral Therapy, Highly Active*/methods , Viral Load*, Anti-HIV Agents/*therapeutic use , HIV Infections/*drug therapy , HIV Infections/*virology , HIV-1/*drug effects, Adult ; Aged ; Anti-HIV Agents/administration & dosage ; CD4 Lymphocyte Count ; Darunavir/administration & dosage ; Drug Resistance, Viral ; Female ; HIV Infections/immunology ; HIV-1/immunology ; Humans ; Lopinavir/administration & dosage ; Male ; Middle Aged ; Ritonavir/administration & dosage ; Treatment Outcome

المؤلفون: Decloedt EH; Division of Clinical Pharmacology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa., Sinxadi PZ; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa., van Zyl GU; Division of Medical Virology, Faculty of Medicine and Health Sciences, Stellenbosch University and National Health Laboratory Service, Cape Town, South Africa., Wiesner L; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa., Khoo S; Institute of Translational Medicine, University of Liverpool and Royal Liverpool University Hospital, Liverpool, UK., Joska JA; Division of Neuropsychiatry, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa., Haas DW; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.; Department of Internal Medicine, Meharry Medical College, Nashville, TN, USA., Maartens G; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

المصدر: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2019 Mar 01; Vol. 74 (3), pp. 699-709.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 7513617 Publication Model: Print Cited Medium: Internet ISSN: 1460-2091 (Electronic) Linking ISSN: 03057453 NLM ISO Abbreviation: J Antimicrob Chemother Subsets: MEDLINE

مواضيع طبية MeSH: Pharmacogenetics*/methods , Pharmacogenomic Variants*, Benzoxazines/*metabolism , Benzoxazines/*pharmacokinetics , Central Nervous System/*metabolism , Reverse Transcriptase Inhibitors/*metabolism , Reverse Transcriptase Inhibitors/*pharmacokinetics, Adult ; Aged ; Alkynes ; Anti-HIV Agents/metabolism ; Anti-HIV Agents/pharmacokinetics ; Blood-Brain Barrier/drug effects ; Blood-Brain Barrier/metabolism ; Central Nervous System/drug effects ; Cognition/drug effects ; Cyclopropanes ; Female ; HIV Infections/drug therapy ; HIV Infections/genetics ; HIV Infections/metabolism ; HIV Infections/virology ; Humans ; Male ; Middle Aged ; Polymorphism, Genetic ; Viral Load ; Young Adult

المؤلفون: Sinxadi PZ; From the Division of Clinical Pharmacology, Department of Medicine, University of Cape Town (PZS, HMM, PJS, GM); Division of Endocrinology and Diabetic Medicine, Department of Medicine, University of Cape Town. Cape Town, South Africa (JAD, NSL); Vanderbilt University School of Medicine, Departments of Medicine, Pharmacology, Pathology, Microbiology & Immunology (DWH); Meharry Medical College, Department of Internal Medicine, Nashville, TN, United States of America (DWH)., McIlleron HM, Dave JA, Smith PJ, Levitt NS, Haas DW, Maartens G

المصدر: Medicine [Medicine (Baltimore)] 2016 Jan; Vol. 95 (2), pp. e2385.

نوع المنشور: Journal Article; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE

مواضيع طبية MeSH: Benzoxazines/*blood , Blood Glucose/*drug effects , HIV Infections/*drug therapy , Lipid Metabolism/*drug effects , Reverse Transcriptase Inhibitors/*blood, Adult ; Alkynes ; Benzoxazines/pharmacology ; Cross-Sectional Studies ; Cyclopropanes ; Female ; Humans ; Lipids/blood ; Male ; Middle Aged ; Prospective Studies ; Reverse Transcriptase Inhibitors/pharmacology

المؤلفون: Sinxadi PZ; Division of Clinical of Pharmacology, Division of Exercise and Endocrine Metabolism, University of Cape Town, Cape Town, South Africa., Leger PD; Vanderbilt University Medical Center, Department of Medicine, Nashville, Tennessee, United States of America., McIlleron HM; Division of Clinical of Pharmacology, Division of Exercise and Endocrine Metabolism, University of Cape Town, Cape Town, South Africa., Smith PJ; Division of Clinical of Pharmacology, Division of Exercise and Endocrine Metabolism, University of Cape Town, Cape Town, South Africa., Dave JA; Division of Exercise and Endocrine Metabolism, Department of Medicine, University of Cape Town, Cape Town, South Africa., Levitt NS; Division of Exercise and Endocrine Metabolism, Department of Medicine, University of Cape Town, Cape Town, South Africa., Maartens G; Division of Clinical of Pharmacology, Division of Exercise and Endocrine Metabolism, University of Cape Town, Cape Town, South Africa., Haas DW; Vanderbilt University School of Medicine, Department of Medicine, Nashville, Tennessee, United States of America.

المصدر: British journal of clinical pharmacology [Br J Clin Pharmacol] 2015 Jul; Vol. 80 (1), pp. 146-56. Date of Electronic Publication: 2015 May 28.

نوع المنشور: Journal Article; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Anti-HIV Agents/*blood , Anti-HIV Agents/*pharmacokinetics , Benzoxazines/*blood , Benzoxazines/*pharmacokinetics , Cytochrome P-450 CYP2B6/*genetics , HIV Infections/*genetics, Adolescent ; Adult ; Alkynes ; Anti-HIV Agents/therapeutic use ; Benzoxazines/therapeutic use ; Black People/genetics ; Child ; Child, Preschool ; Constitutive Androstane Receptor ; Cyclopropanes ; Female ; Genotype ; HIV Infections/blood ; HIV Infections/drug therapy ; Humans ; Male ; Middle Aged ; Polymorphism, Single Nucleotide/genetics ; South Africa ; Young Adult

المؤلفون: van der Westhuizen FH; Centre for Human Metabonomics, North-West University, Potchefstroom, South Africa., Sinxadi PZ, Dandara C, Smuts I, Riordan G, Meldau S, Malik AN, Sweeney MG, Tsai Y, Towers GW, Louw R, Gorman GS, Payne BA, Soodyall H, Pepper MS, Elson JL

المصدر: Human mutation [Hum Mutat] 2015 May; Vol. 36 (5), pp. 569-71.

نوع المنشور: Congress; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 9215429 Publication Model: Print Cited Medium: Internet ISSN: 1098-1004 (Electronic) Linking ISSN: 10597794 NLM ISO Abbreviation: Hum Mutat Subsets: MEDLINE

مواضيع طبية MeSH: DNA, Mitochondrial* , Genetic Variation* , Genetics, Population*, Black People/*genetics, Africa, Southern ; Genetic Association Studies ; Genetic Predisposition to Disease ; Humans ; Mitochondrial Diseases/diagnosis ; Mitochondrial Diseases/genetics

المؤلفون: Sinxadi PZ; University of Cape Town Medical School, Department of Medicine, University of Cape Town, Cape Town, South Africa. phumla.sinxadi@uct.ac.za, Dave JA, Samuels DC, Heckmann JM, Maartens G, Levitt NS, Wester CW, Haas DW, Hulgan T

المصدر: AIDS research and human retroviruses [AIDS Res Hum Retroviruses] 2013 Jul; Vol. 29 (7), pp. 1031-9. Date of Electronic Publication: 2013 Mar 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Mary Ann Liebert Country of Publication: United States NLM ID: 8709376 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1931-8405 (Electronic) Linking ISSN: 08892229 NLM ISO Abbreviation: AIDS Res Hum Retroviruses Subsets: MEDLINE

مواضيع طبية MeSH: Anti-HIV Agents/*adverse effects , DNA, Mitochondrial/*genetics , HIV Infections/*drug therapy , HIV Infections/*genetics , Metabolic Diseases/*etiology , Metabolic Diseases/*genetics, Adult ; Black People/genetics ; Cross-Sectional Studies ; Female ; Genetic Predisposition to Disease ; Genetic Variation ; Genome, Mitochondrial ; HIV Infections/complications ; HIV-Associated Lipodystrophy Syndrome/etiology ; HIV-Associated Lipodystrophy Syndrome/genetics ; Humans ; Hypertriglyceridemia/etiology ; Hypertriglyceridemia/genetics ; Male ; Pilot Projects ; Polyneuropathies/etiology ; Polyneuropathies/genetics ; South Africa