المؤلفون: Haley E. Speed, John P. Welsh, Zhiyi Zhu, Jonathan D. Lautz, Smith Sep

مصطلحات موضوعية: Mutation, Glutamatergic, Electrical Synapses, medicine.anatomical_structure, medicine, Chemical synaptic transmission, Electrical synapse, Biology, Neurotransmission, Glutamatergic postsynaptic density, medicine.disease_cause, Neuroscience, Intracellular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1d17a50a57dfe2a5836ee658dc17bd34
https://doi.org/10.1101/2021.03.25.437056

المؤلفون: Smith Sep, Jan-Marino Ramirez, Franck Kalume, Wehle Dt, Achira Roy, Kathleen J. Millen, Han Vz, Angela M. Bard

مصطلحات موضوعية: Epilepsy, business.industry, Mutant, medicine, P110α, Hippocampal formation, Signal transduction, medicine.disease, business, Protein kinase B, Neuroscience, Potassium channel, PI3K/AKT/mTOR pathway

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::124f364f85ecbfb7db44eab2697c53d7
https://doi.org/10.1101/2021.03.03.433821

المؤلفون: Stamenkovic V; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Lautz JD; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Harsh FM; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Smith SEP; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA. seps@uw.edu.; Department of Pediatrics, University of Washington, Seattle, WA, USA. seps@uw.edu.; Graduate Program in Neuroscience, University of Washington, Seattle, WA, USA. seps@uw.edu.

المصدر: Molecular psychiatry [Mol Psychiatry] 2024 May; Vol. 29 (5), pp. 1392-1405. Date of Electronic Publication: 2024 Jan 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE

مواضيع طبية MeSH: Fragile X Syndrome*/metabolism , Fragile X Syndrome*/drug therapy , Fragile X Mental Retardation Protein*/metabolism , Fragile X Mental Retardation Protein*/genetics , Disease Models, Animal* , src-Family Kinases*/metabolism , Benzodioxoles*/pharmacology , Proto-Oncogene Proteins c-fyn*/metabolism , Neurons*/metabolism , Neurons*/drug effects, Animals ; Mice ; Male ; Receptors, Metabotropic Glutamate/metabolism ; Signal Transduction/drug effects ; Phenotype ; Synapses/metabolism ; Synapses/drug effects ; Protein Interaction Maps/drug effects ; Receptors, N-Methyl-D-Aspartate/metabolism ; Mice, Inbred C57BL ; Mice, Knockout ; Cerebral Cortex/metabolism ; Cerebral Cortex/drug effects ; Quinazolines

المؤلفون: Ritmeester-Loy SA; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA 98101, USA., Draper IH; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA 98101, USA., Bueter EC; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA 98101, USA., Lautz JD; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA 98101, USA., Zhang-Wong Y; Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute, Seattle, WA 98101, USA., Gustafson JA; Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute, Seattle, WA 98101, USA.; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, WA 98101, USA., Wilson AL; Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute, Seattle, WA 98101, USA.; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, WA 98101, USA., Lin C; Proteomics and Metabolomics Facility, Fred Hutchinson Cancer Center, Seattle, WA 98101, USA., Gafken PR; Proteomics and Metabolomics Facility, Fred Hutchinson Cancer Center, Seattle, WA 98101, USA., Jensen MC; Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute, Seattle, WA 98101, USA.; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, WA 98101, USA.; Department of Pediatrics, University of Washington, Seattle, WA 98101, USA., Orentas R; Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute, Seattle, WA 98101, USA.; Department of Pediatrics, University of Washington, Seattle, WA 98101, USA., Smith SEP; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA 98101, USA.; Department of Pediatrics, University of Washington, Seattle, WA 98101, USA.; Graduate Program in Neuroscience, University of Washington, Seattle, WA 98101, USA.

المصدر: Science signaling [Sci Signal] 2024 Mar 05; Vol. 17 (826), pp. eadd4671. Date of Electronic Publication: 2024 Mar 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction* , Adaptor Proteins, Signal Transducing*, Antigens, CD19/genetics ; Cell Membrane ; Receptors, Antigen, T-Cell/genetics

المؤلفون: Wehle DT; Graduate Program in Neuroscience, University of Washington, Seattle, Washington, USA; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington, USA., Bass CS; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington, USA., Sulc J; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington, USA., Mirzaa G; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington, USA; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA; Brotman Baty Institute for Precision Medicine, Seattle, Washington, USA., Smith SEP; Graduate Program in Neuroscience, University of Washington, Seattle, Washington, USA; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington, USA; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA. Electronic address: seps@uw.edu.

المصدر: The Journal of biological chemistry [J Biol Chem] 2023 Nov; Vol. 299 (11), pp. 105271. Date of Electronic Publication: 2023 Sep 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction* , TOR Serine-Threonine Kinases*/antagonists & inhibitors , TOR Serine-Threonine Kinases*/genetics , TOR Serine-Threonine Kinases*/metabolism, Animals ; Mice ; Phosphorylation ; Protein Interaction Maps ; Protein Kinase Inhibitors/pharmacology ; NIH 3T3 Cells ; Cells, Cultured ; Humans ; MAP Kinase Signaling System/drug effects ; Mutation

المؤلفون: Stillman M; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.; Dartmouth-Hitchcock Medical Center Psychiatry Residency Program, Dartmouth, NH, USA., Lautz JD; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Johnson RS; Department of Genome Sciences, University of Washington, Seattle, WA, USA., MacCoss MJ; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Smith SEP; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA. seps@uw.edu.; Department of Pediatrics, University of Washington, Seattle, WA, USA. seps@uw.edu.; Graduate Program in Neuroscience, University of Washington, Seattle, WA, USA. seps@uw.edu.

المصدر: Scientific reports [Sci Rep] 2022 Feb 25; Vol. 12 (1), pp. 3207. Date of Electronic Publication: 2022 Feb 25.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Neurons*/metabolism , Synapses*/metabolism, Animals ; Cerebral Cortex/metabolism ; Homer Scaffolding Proteins/genetics ; Homer Scaffolding Proteins/metabolism ; Mice ; Mice, Knockout ; Microfilament Proteins/metabolism ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism

المؤلفون: Lautz JD; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Tsegay KB; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Zhu Z; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Gniffke EP; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Welsh JP; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA; Department of Pediatrics, University of Washington, Seattle, WA, USA., Smith SEP; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA; Department of Pediatrics, University of Washington, Seattle, WA, USA; Graduate Program in Neuroscience, University of Washington, Seattle, WA, USA. Electronic address: seps@uw.edu.

المصدر: Cell reports [Cell Rep] 2021 Nov 30; Vol. 37 (9), pp. 110076.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Protein Interaction Maps*, Blinking/*drug effects , Brain/*metabolism , Methoxyhydroxyphenylglycol/*analogs & derivatives , N-Methylaspartate/*pharmacology , Proteome/*metabolism , Synapses/*metabolism, Animals ; Brain/drug effects ; Conditioning, Eyelid ; Excitatory Amino Acid Agonists/pharmacology ; Female ; Male ; Methoxyhydroxyphenylglycol/pharmacology ; Mice ; Neuronal Plasticity ; Proteome/analysis ; Synapses/drug effects

المؤلفون: Roy A; Neuroscience Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Bengaluru, India., Han VZ; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, United States.; Department of Biology, University of Washington, Seattle, WA, United States., Bard AM; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, United States., Wehle DT; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, United States.; Graduate Program in Neuroscience, University of Washington, Seattle, WA, United States., Smith SEP; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, United States.; Department of Pediatrics, University of Washington, Seattle, WA, United States., Ramirez JM; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, United States.; Department of Pediatrics, University of Washington, Seattle, WA, United States.; Department of Neurological Surgery, University of Washington, Seattle, WA, United States.; Department of Physiology and Biophysics, University of Washington, Seattle, WA, United States., Kalume F; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, United States.; Department of Neurological Surgery, University of Washington, Seattle, WA, United States.; Department of Pharmacology, University of Washington, Seattle, WA, United States., Millen KJ; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, United States.; Department of Pediatrics, University of Washington, Seattle, WA, United States.

المصدر: Frontiers in molecular neuroscience [Front Mol Neurosci] 2021 Nov 26; Vol. 14, pp. 772847. Date of Electronic Publication: 2021 Nov 26 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101477914 Publication Model: eCollection Cited Medium: Print ISSN: 1662-5099 (Print) Linking ISSN: 16625099 NLM ISO Abbreviation: Front Mol Neurosci Subsets: PubMed not MEDLINE

المؤلفون: Negraes PD; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Trujillo CA; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA. clebertrujillo@gmail.com., Yu NK; Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA, USA., Wu W; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Yao H; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Liang N; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Lautz JD; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.; Graduate Program in Neuroscience, University of Washington, Seattle, WA, USA., Kwok E; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., McClatchy D; Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA, USA., Diedrich J; Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA, USA., de Bartolome SM; Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA, USA., Truong J; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Szeto R; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Tran T; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Herai RH; Experimental Multiuser Laboratory, Graduate Program in Health Sciences, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil., Smith SEP; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.; Graduate Program in Neuroscience, University of Washington, Seattle, WA, USA., Haddad GG; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Department of Neurosciences, University of California San Diego, La Jolla, CA, USA., Yates JR 3rd; Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA, USA., Muotri AR; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA. muotri@ucsd.edu.; Kavli Institute for Brain and Mind, University of California San Diego, La Jolla, CA, USA. muotri@ucsd.edu.; Center for Academic Research and Training in Anthropogeny (CARTA), La Jolla, CA, USA. muotri@ucsd.edu.

المصدر: Molecular psychiatry [Mol Psychiatry] 2021 Nov; Vol. 26 (11), pp. 7047-7068. Date of Electronic Publication: 2021 Apr 22.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE

مواضيع طبية MeSH: Epileptic Syndromes*/genetics, Animals ; Humans ; Mice ; Neurons/metabolism ; Protein Serine-Threonine Kinases ; Proteomics

المؤلفون: Tsegay KB; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, United States., Adeyemi CM; St. Louis University School of Medicine, Department of Pharmacology and Physiology, St. Louis, MO, United States., Gniffke EP; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, United States., Sather DN; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, United States.; Department of Pediatrics, University of Washington, Seattle, WA, United States., Walker JK; St. Louis University School of Medicine, Department of Pharmacology and Physiology, St. Louis, MO, United States.; Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University St. Louis, Seattle, WA, United States., Smith SEP; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, United States.; Department of Pediatrics, University of Washington, Seattle, WA, United States.; Graduate Program in Neuroscience, University of Washington, Seattle, WA, United States.

المصدر: Frontiers in pharmacology [Front Pharmacol] 2021 Jun 14; Vol. 12, pp. 685308. Date of Electronic Publication: 2021 Jun 14 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE