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المؤلفون: Deborah S. Mortensen, Sayee G. Hegde, Sophie M. Perrin-Ninkovic, Sogole Bahmanyar, Meg McCarrick, Roy Harris, Robert Hilgraf, Branden G. S. Lee, Jeff McKie, Lisa Nadolny, John Sapienza, Alice Collette, Sarah Cox, James C. Gamez, Jennifer L. Hensel, Xuequn Helen Hua, Jim Leisten, Heather K. Raymon, Tam Tran, Rama Krishna Narla
المصدر: Medicinal Chemistry Research.
مصطلحات موضوعية: Organic Chemistry, General Pharmacology, Toxicology and Pharmaceutics
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2
المؤلفون: Mark A. Nagy, Robert Hilgraf, Deborah S. Mortensen, Jan Elsner, Stephen Norris, Jayashree Tikhe, Won Yoon, David Paisner, Mercedes Delgado, Paul Erdman, Jason Haelewyn, Godrej Khambatta, Li Xu, William J. Romanow, Kevin Condroski, Sogole Bahmanyar, Meg McCarrick, Brent Benish, Kate Blease, Laurie LeBrun, Mehran F. Moghaddam, Julius Apuy, Stacie S. Canan, Brydon L. Bennett, Yoshitaka Satoh
المصدر: Journal of Medicinal Chemistry. 64:18193-18208
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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3
المؤلفون: Dan Zhu, Xiaohui Peng, Dale Robinson, Riggs Jennifer, Kimberly E. Fultz, Julius Apuy, Tam Minh Tran, Jan Elsner, Rama K. Narla, Katerina Leftheris, Sogole Bahmanyar, Dan Cashion, Lida Tehrani, Laurie LeBrun, John F. Boylan
المصدر: Journal of Medicinal Chemistry. 64:12670-12679
مصطلحات موضوعية: Models, Molecular, Antineoplastic Agents, Breast Neoplasms, Cell Cycle Proteins, Protein Serine-Threonine Kinases, Gene Expression Regulation, Enzymologic, Structure-Activity Relationship, In vivo, Cell Line, Tumor, Drug Discovery, Humans, Potency, IC50, Triple-negative breast cancer, Antitumor activity, chemistry.chemical_classification, Molecular Structure, Chemistry, Protein-Tyrosine Kinases, Gene Expression Regulation, Neoplastic, Molecular Docking Simulation, Spindle checkpoint, Enzyme, Cell culture, Cancer research, Molecular Medicine, Female
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4
المؤلفون: Kate Blease, Garth Ringheim, Eduardo Torres, Jeffrey Muir, Laurie LeBrun, Veronique Plantevin-Krenitsky, Ashutosh Kulkarni, Maria Celeridad, Eun Mi Hur, Hegde Sayee Gajanan, Dehua Huang, Brian E. Cathers, John Sapienza, Henry Chan, Brydon Bennett, Katerina Leftheris, Correa Matthew D, Zheng Liu, Deborah S Mortensen, Brandon Whitefield, Mercedes Delgado, Dan Cashion, Sogole Bahmanyar, Lisa Morrison, Roli Khattri, Jason Parnes, Stephen Norris, Roy Harris, Kelven Burnett, Joshua Hansen, Godrej Khambatta, Patrick Papa
المصدر: Journal of Medicinal Chemistry. 64:11886-11903
مصطلحات موضوعية: Male, Gene isoform, T-Lymphocytes, T cell, Graft vs Host Disease, Lymphocyte Activation, Structure-Activity Relationship, In vivo, Drug Discovery, medicine, Animals, Humans, Immunologic Factors, Receptor, Protein Kinase Inhibitors, Protein kinase C, Cell Proliferation, Molecular Structure, Chemistry, Kinase, T-cell receptor, Cyclohexanols, Cell biology, Mice, Inbred C57BL, Molecular Docking Simulation, Protein Kinase C-delta, Pyrimidines, medicine.anatomical_structure, Protein Kinase C-theta, Molecular Medicine, Amine gas treating, Caco-2 Cells, Protein Binding
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5
المؤلفون: Shuichan Xu, Tam Tran, Dan Zhu, Tao Shi, David Mikolon, Jim Leisten, Philip Chamberlain, Laurie LeBrun, Sogole Bahmanyar, Ning Jiang, Jingjing Zhao, Mehnaz Malek, Ellen Filvaroff, Heather Raymon, Robert Hubbard, John Boylan
المصدر: Cancer Research. 82:1180-1180
مصطلحات موضوعية: Cancer Research, Oncology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5a33a93f513c2d86beb88b43e572e87c
https://doi.org/10.1158/1538-7445.am2022-1180 -
6
المؤلفون: Xiaohui Peng, Rama K. Narla, Kevin Ronald Condroski, Nagy Mark A, John F. Boylan, Jennifer Riggs, Jan Elsner, Ashutosh A. Kulkarni, Dale Robinson, Kimberly Elizabeth Fultz, Dan Zhu, Tam Tran, Dan Cashion, Lida Tehrani, Katerina Leftheris, Laurie LeBrun, Barbra Pagarigan, Sogole Bahmanyar, Gustavo Fenalti
المصدر: Journal of medicinal chemistry. 62(9)
مصطلحات موضوعية: Antineoplastic Agents, Apoptosis, Triple Negative Breast Neoplasms, Docetaxel, Mice, SCID, Protein Serine-Threonine Kinases, 01 natural sciences, 03 medical and health sciences, CLK2, Structure-Activity Relationship, Pharmacokinetics, Drug Discovery, Structure–activity relationship, Animals, Kinome, Single agent, Pyrroles, Phosphorylation, Protein Kinase Inhibitors, Triple-negative breast cancer, 030304 developmental biology, 0303 health sciences, Molecular Structure, Chemistry, Xenograft Model Antitumor Assays, 0104 chemical sciences, Rats, 010404 medicinal & biomolecular chemistry, TTK PROTEIN KINASE, Orally active, Pyrimidines, Drug Design, Cancer research, Molecular Medicine, Female, Microtubule-Associated Proteins
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7
المؤلفون: Sogole Bahmanyar, Brian E. Cathers, Mehran F. Moghaddam, Peter Worland, Lida Tehrani, Brandon Wade Whitefield, Heather Raymon, James C. Gamez, Godrej Khambatta, Julius Apuy, Samantha J. Richardson, Rene R. Bisonette, Jingjing Zhao, Graziella I. Shevlin, Deborah Mortensen, Matt Hickman, Jan Elsner, Correa Matthew D, Roy L. Harris, Sophie Perrin-Ninkovic, Rama K. Narla, Jennifer Riggs, Kimberly Elizabeth Fultz, Sabita Sankar, Patrick Papa, John Sapienza, Stacie S. Canan, Sophie X. Peng, Jason Simon Parnes, Garrick Packard, Jim Leisten, Branden Lee
المصدر: Journal of Medicinal Chemistry. 58:5599-5608
مصطلحات موضوعية: Protein Conformation, Triazole, mTORC1, Pharmacology, mTORC2, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Cell Line, Tumor, Drug Discovery, Animals, Humans, Structure–activity relationship, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Cell Proliferation, Dose-Response Relationship, Drug, Chemistry, Kinase, TOR Serine-Threonine Kinases, Triazoles, Xenograft Model Antitumor Assays, Rats, Molecular Docking Simulation, Biochemistry, Drug Design, Pyrazines, Molecular Medicine, Signal Transduction
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8
المؤلفون: Jason Simon Parnes, Rene R. Bisonette, Sophie Perrin-Ninkovic, Deborah Mortensen, Branden Lee, Peter Worland, James C. Gamez, Graziella I. Shevlin, Matt Hickman, Stacie S. Canan, Julius Apuy, Samantha J. Richardson, Jingjing Zhao, Godrej Khambatta, Sophie X. Peng, Jim Leisten, Garrick Packard, Correa Matthew D, Rama K. Narla, Lida Tehrani, Jennifer Riggs, Heather Raymon, Jan Elsner, Roy L. Harris, Kimberly Elizabeth Fultz, Patrick Papa, Sogole Bahmanyar, Brandon Wade Whitefield, Sabita Sankar, John Sapienza, Mehran F. Moghaddam, Brian E. Cathers
المصدر: Journal of Medicinal Chemistry. 58:5323-5333
مصطلحات موضوعية: Male, Models, Molecular, Antineoplastic Agents, Pharmacology, MTOR Kinase Inhibitor CC-223, Structure-Activity Relationship, In vivo, Drug Discovery, Tumor Cells, Cultured, Animals, Humans, Structure–activity relationship, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Phosphoinositide-3 Kinase Inhibitors, Molecular Structure, Drug discovery, Chemistry, Kinase, TOR Serine-Threonine Kinases, RPTOR, Prostatic Neoplasms, Rats, Inhibitory potency, Pyrazines, Molecular Medicine, Signal Transduction
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9
المؤلفون: V. Maggiotti, Marina Resmini, Sogole Bahmanyar, Veronique Gouverneur, Maud Reiter, Kendall N. Houk
المصدر: Tetrahedron. 60:619-632
مصطلحات موضوعية: biology, Stereochemistry, Chemistry, Organic Chemistry, Aldolase A, Enantioselective synthesis, Regioselectivity, General Medicine, Biochemistry, Acceptor, Catalysis, Aldol reaction, Drug Discovery, Structural isomer, biology.protein, Enantiomer
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المؤلفون: Sogole Bahmanyar, Harry J. Martin, Benjamin List, Kendall N. Houk
المصدر: Journal of the American Chemical Society. 125:2475-2479
مصطلحات موضوعية: Models, Molecular, Aldehydes, Proline, Cyclohexanones, Intermolecular force, Cyclohexanone, Stereoisomerism, General Chemistry, Biochemistry, Catalysis, Benzaldehyde, chemistry.chemical_compound, Hajos–Parrish–Eder–Sauer–Wiechert reaction, Colloid and Surface Chemistry, chemistry, Organic reaction, Aldol reaction, Alcohols, Benzaldehydes, Quantum Theory, Thermodynamics, Organic chemistry, Aldol condensation, Isobutyraldehyde