نتائج البحث - "Son of Sevenless Protein, Drosophila"

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دورية أكاديمية

Interactions of the N- and C-Terminal SH3 Domains of Drosophila Drk with the Proline-Rich Peptides from Sos and Dos.

المؤلفون: Sayeesh PM; Department of Chemistry, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo 192-0373, Japan., Iguchi M; Department of Chemistry, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo 192-0373, Japan., Suemoto Y; Department of Chemistry, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo 192-0373, Japan., Inoue J; Department of Chemistry, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo 192-0373, Japan., Inomata K; Department of Chemistry, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo 192-0373, Japan., Ikeya T; Department of Chemistry, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo 192-0373, Japan., Ito Y; Department of Chemistry, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo 192-0373, Japan.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2023 Sep 15; Vol. 24 (18). Date of Electronic Publication: 2023 Sep 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Drosophila* , Nuclear Family*, Animals ; Humans ; Peptides ; Proline ; src Homology Domains ; Tyrosine ; Son of Sevenless Protein, Drosophila

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دورية أكاديمية

A Sos proteomimetic as a pan-Ras inhibitor.

المؤلفون: Hong SH; Department of Chemistry, New York University, New York, NY 10003., Yoo DY; Department of Chemistry, New York University, New York, NY 10003., Conway L; Department of Chemistry, The Scripps Research Institute, Jupiter, FL 33458., Richards-Corke KC; Department of Chemistry, New York University, New York, NY 10003., Parker CG; Department of Chemistry, The Scripps Research Institute, Jupiter, FL 33458., Arora PS; Department of Chemistry, New York University, New York, NY 10003; arora@nyu.edu.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 May 04; Vol. 118 (18).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

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دورية أكاديمية

Disordered proteins mitigate the temperature dependence of site-specific binding free energies.

المؤلفون: Thole JF; Department of Chemistry, UNC-Chapel Hill, Chapel Hill, North Carolina, USA; Molecular and Cellular Biophysics Program, UNC-Chapel Hill, Chapel Hill, North Carolina, USA., Waudby CA; School of Pharmacy, University College London, London, United Kingdom., Pielak GJ; Department of Chemistry, UNC-Chapel Hill, Chapel Hill, North Carolina, USA; Molecular and Cellular Biophysics Program, UNC-Chapel Hill, Chapel Hill, North Carolina, USA; Department of Biochemistry & Biophysics, UNC-Chapel Hill, Chapel Hill, North Carolina, USA; Lineberger Cancer Center, UNC-Chapel Hill, Chapel Hill, North Carolina, USA; Integrative Program for Biological and Genome Sciences, UNC - Chapel Hill, Chapel Hill, North Carolina, USA. Electronic address: gary_pielak@unc.edu.

المصدر: The Journal of biological chemistry [J Biol Chem] 2023 Mar; Vol. 299 (3), pp. 102984. Date of Electronic Publication: 2023 Feb 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drosophila melanogaster*/metabolism , Intrinsically Disordered Proteins*/chemistry , Drosophila Proteins*/chemistry, Animals ; Binding Sites ; Entropy ; Peptides/metabolism ; Protein Binding ; src Homology Domains ; Temperature ; Son of Sevenless Protein, Drosophila/chemistry

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دورية أكاديمية

Time-Series Chlorophyll Fluorescence Imaging Reveals Dynamic Photosynthetic Fingerprints of sos Mutants to Drought Stress.

المؤلفون: Sun D; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China. dzs0015@zju.edu.cn.; Key Laboratory of Spectroscopy Sensing, Ministry of Agriculture and Rural Affairs, Hangzhou 310058, China. dzs0015@zju.edu.cn., Zhu Y; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China. zhukvo@zju.edu.cn.; Key Laboratory of Spectroscopy Sensing, Ministry of Agriculture and Rural Affairs, Hangzhou 310058, China. zhukvo@zju.edu.cn., Xu H; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China. haixiaxu@zju.edu.cn.; Key Laboratory of Spectroscopy Sensing, Ministry of Agriculture and Rural Affairs, Hangzhou 310058, China. haixiaxu@zju.edu.cn., He Y; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China. yhe@zju.edu.cn.; Key Laboratory of Spectroscopy Sensing, Ministry of Agriculture and Rural Affairs, Hangzhou 310058, China. yhe@zju.edu.cn.; State Key Laboratory of Modern Optical Instrumentation, Zhejiang University, Hangzhou 310058, China. yhe@zju.edu.cn., Cen H; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China. hycen@zju.edu.cn.; Key Laboratory of Spectroscopy Sensing, Ministry of Agriculture and Rural Affairs, Hangzhou 310058, China. hycen@zju.edu.cn.; State Key Laboratory of Modern Optical Instrumentation, Zhejiang University, Hangzhou 310058, China. hycen@zju.edu.cn.

المصدر: Sensors (Basel, Switzerland) [Sensors (Basel)] 2019 Jun 12; Vol. 19 (12). Date of Electronic Publication: 2019 Jun 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101204366 Publication Model: Electronic Cited Medium: Internet ISSN: 1424-8220 (Electronic) Linking ISSN: 14248220 NLM ISO Abbreviation: Sensors (Basel) Subsets: MEDLINE

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دورية أكاديمية

Dynamic Scaling Analysis of Molecular Motion within the LAT:Grb2:SOS Protein Network on Membranes.

المؤلفون: Huang WYC; Department of Chemistry, University of California, Berkeley, Berkeley, California., Chiang HK; Department of Chemistry, University of California, Berkeley, Berkeley, California., Groves JT; Department of Chemistry, University of California, Berkeley, Berkeley, California. Electronic address: jtgroves@lbl.gov.

المصدر: Biophysical journal [Biophys J] 2017 Oct 17; Vol. 113 (8), pp. 1807-1813.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370626 Publication Model: Print Cited Medium: Internet ISSN: 1542-0086 (Electronic) Linking ISSN: 00063495 NLM ISO Abbreviation: Biophys J Subsets: MEDLINE

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دورية أكاديمية

Monitoring Ras Interactions with the Nucleotide Exchange Factor Son of Sevenless (Sos) Using Site-specific NMR Reporter Signals and Intrinsic Fluorescence.

المؤلفون: Vo U; From the Manchester Institute of Biotechnology and Faculty of Life Sciences, The University of Manchester, 131 Princess Street, Manchester M1 7DN, United Kingdom and., Vajpai N; Discovery Sciences, AstraZeneca, Mereside, Alderley Park, Cheshire SK10 4TF, United Kingdom., Flavell L; Discovery Sciences, AstraZeneca, Mereside, Alderley Park, Cheshire SK10 4TF, United Kingdom., Bobby R; Discovery Sciences, AstraZeneca, Mereside, Alderley Park, Cheshire SK10 4TF, United Kingdom., Breeze AL; Discovery Sciences, AstraZeneca, Mereside, Alderley Park, Cheshire SK10 4TF, United Kingdom., Embrey KJ; Discovery Sciences, AstraZeneca, Mereside, Alderley Park, Cheshire SK10 4TF, United Kingdom. Electronic address: Kevin.Embrey@astrazeneca.com., Golovanov AP; From the Manchester Institute of Biotechnology and Faculty of Life Sciences, The University of Manchester, 131 Princess Street, Manchester M1 7DN, United Kingdom and. Electronic address: A.Golovanov@manchester.ac.uk.

المصدر: The Journal of biological chemistry [J Biol Chem] 2016 Jan 22; Vol. 291 (4), pp. 1703-1718. Date of Electronic Publication: 2015 Nov 12.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

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دورية أكاديمية

DRK/DOS/SOS converge with Crk/Mbc/dCed-12 to activate Rac1 during glial engulfment of axonal debris.

المؤلفون: Lu TY; Department of Neurobiology and Howard Hughes Medical Institute, University of Massachusetts Medical School, Worcester, MA 01605., Doherty J; Department of Neurobiology and Howard Hughes Medical Institute, University of Massachusetts Medical School, Worcester, MA 01605., Freeman MR; Department of Neurobiology and Howard Hughes Medical Institute, University of Massachusetts Medical School, Worcester, MA 01605 marc.freeman@umassmed.edu.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2014 Aug 26; Vol. 111 (34), pp. 12544-9. Date of Electronic Publication: 2014 Aug 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Drosophila Proteins/*physiology , Drosophila melanogaster/*cytology , Drosophila melanogaster/*physiology , Eye Proteins/*physiology , Neuroglia/*physiology , Son of Sevenless Protein, Drosophila/*physiology , rac GTP-Binding Proteins/*physiology, Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/physiology ; Animals ; Animals, Genetically Modified ; Axons/physiology ; Cytoskeletal Proteins/genetics ; Cytoskeletal Proteins/physiology ; Drosophila Proteins/genetics ; Drosophila melanogaster/genetics ; Eye Proteins/genetics ; Genes, Insect ; Mutation ; Nerve Degeneration ; Phagosomes/physiology ; Proto-Oncogene Proteins c-crk/genetics ; Proto-Oncogene Proteins c-crk/physiology ; Son of Sevenless Protein, Drosophila/genetics ; rac GTP-Binding Proteins/genetics ; ras Proteins/genetics ; ras Proteins/physiology

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دورية أكاديمية

Molecular kinetics. Ras activation by SOS: allosteric regulation by altered fluctuation dynamics.

المؤلفون: Iversen L; Howard Hughes Medical Institute, Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA., Tu HL; Howard Hughes Medical Institute, Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA., Lin WC; Howard Hughes Medical Institute, Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA., Christensen SM; Howard Hughes Medical Institute, Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA., Abel SM; Department of Chemical Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA., Iwig J; Howard Hughes Medical Institute, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA., Wu HJ; Howard Hughes Medical Institute, Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA., Gureasko J; Howard Hughes Medical Institute, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA., Rhodes C; Department of Mechanical Engineering, University of California, Berkeley, Berkeley, CA 94720, USA., Petit RS; Howard Hughes Medical Institute, Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA., Hansen SD; Howard Hughes Medical Institute, Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA., Thill P; Department of Chemistry, MIT, Cambridge, MA 02139, USA., Yu CH; Mechanobiology Institute, National University of Singapore, Singapore., Stamou D; Department of Chemistry and Nano-Science Center, University of Copenhagen, Copenhagen, Denmark., Chakraborty AK; Department of Chemical Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA. Department of Chemistry, MIT, Cambridge, MA 02139, USA. Department of Biological Engineering, MIT, Cambridge, MA 02139, USA. Ragon Institute of Massachusetts General Hospital, MIT, and Harvard, Cambridge, MA 02139, USA. Department of Physics, MIT, Cambridge, MA 02139, USA. Institute for Medical Engineering and Science, MIT, Cambridge, MA 02139, USA., Kuriyan J; Howard Hughes Medical Institute, Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA. Howard Hughes Medical Institute, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA. Physical Biosciences and Materials Sciences Divisions, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Groves JT; Howard Hughes Medical Institute, Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA. Mechanobiology Institute, National University of Singapore, Singapore. Physical Biosciences and Materials Sciences Divisions, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. Berkeley Education Alliance for Research in Singapore, 1 Create Way, CREATE tower level 11, University Town, Singapore 138602. jtgroves@lbl.gov.

المصدر: Science (New York, N.Y.) [Science] 2014 Jul 04; Vol. 345 (6192), pp. 50-4.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Protein Interaction Domains and Motifs*, Proto-Oncogene Proteins p21(ras)/*agonists , Son of Sevenless Protein, Drosophila/*chemistry, Allosteric Regulation ; Catalytic Domain ; Crystallography, X-Ray ; Enzyme Activation ; Humans ; Kinetics ; Nucleotides/chemistry ; Son of Sevenless Protein, Drosophila/genetics

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دورية أكاديمية

Lycopene Triggers Nrf2-AMPK Cross Talk to Alleviate Atrazine-Induced Nephrotoxicity in Mice.

المؤلفون: Lin J; College of Veterinary Medicine , ‡Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment , and §Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine , Northeast Agricultural University , Harbin 150030 , P.R. China., Xia J; College of Veterinary Medicine , ‡Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment , and §Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine , Northeast Agricultural University , Harbin 150030 , P.R. China., Zhao HS; College of Veterinary Medicine , ‡Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment , and §Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine , Northeast Agricultural University , Harbin 150030 , P.R. China., Hou R; College of Veterinary Medicine , ‡Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment , and §Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine , Northeast Agricultural University , Harbin 150030 , P.R. China., Talukder M; College of Veterinary Medicine , ‡Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment , and §Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine , Northeast Agricultural University , Harbin 150030 , P.R. China.; Department of Physiology and Pharmacology, Faculty of Animal Science and Veterinary Medicine , Patuakhali Science and Technology University , Barishal 8210 , Bangladesh., Yu L; College of Veterinary Medicine , ‡Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment , and §Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine , Northeast Agricultural University , Harbin 150030 , P.R. China., Guo JY; College of Veterinary Medicine , ‡Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment , and §Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine , Northeast Agricultural University , Harbin 150030 , P.R. China., Li JL; College of Veterinary Medicine , ‡Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment , and §Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine , Northeast Agricultural University , Harbin 150030 , P.R. China.

المصدر: Journal of agricultural and food chemistry [J Agric Food Chem] 2018 Nov 21; Vol. 66 (46), pp. 12385-12394. Date of Electronic Publication: 2018 Nov 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE

مواضيع طبية MeSH: Atrazine/*toxicity , Herbicides/*toxicity , Kidney Diseases/*drug therapy , Lycopene/*administration & dosage , NF-E2-Related Factor 2/*metabolism , Protein Kinases/*metabolism, AMP-Activated Protein Kinase Kinases ; Animals ; Autophagy/drug effects ; Glutathione Peroxidase/genetics ; Glutathione Peroxidase/metabolism ; Humans ; Hydrogen Peroxide/metabolism ; Kidney/drug effects ; Kidney/metabolism ; Kidney Diseases/etiology ; Kidney Diseases/genetics ; Kidney Diseases/metabolism ; Male ; Mice ; NF-E2-Related Factor 2/genetics ; Oxidative Stress/drug effects ; Protein Kinases/genetics ; Son of Sevenless Protein, Drosophila/genetics ; Son of Sevenless Protein, Drosophila/metabolism

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دورية أكاديمية

Son of sevenless directly links the Robo receptor to rac activation to control axon repulsion at the midline.

المؤلفون: Yang L; Department of Neuroscience, University of Pennsylvania School of Medicine, 421 Curie Boulevard, Philadelphia, Pennsylvania 19104, USA., Bashaw GJ

المصدر: Neuron [Neuron] 2006 Nov 22; Vol. 52 (4), pp. 595-607.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print Cited Medium: Print ISSN: 0896-6273 (Print) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE

مواضيع طبية MeSH: Drosophila/*embryology , Drosophila/*metabolism , Growth Cones/*metabolism , Nerve Tissue Proteins/*metabolism , Nervous System/*embryology , Nervous System/*metabolism , Receptors, Immunologic/*metabolism , Son of Sevenless Protein, Drosophila/*metabolism , rac GTP-Binding Proteins/*metabolism, Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Cell Communication/physiology ; Cell Line, Tumor ; Cell Membrane/metabolism ; Cues ; Cytoskeleton/genetics ; Cytoskeleton/metabolism ; Drosophila/cytology ; Drosophila Proteins ; Gene Expression Regulation, Developmental/physiology ; Growth Cones/ultrastructure ; Humans ; Nerve Tissue Proteins/genetics ; Nervous System/cytology ; Protein Structure, Tertiary/physiology ; Protein Transport/physiology ; Receptors, Immunologic/genetics ; Signal Transduction/physiology ; Son of Sevenless Protein, Drosophila/chemistry ; Son of Sevenless Protein, Drosophila/genetics ; rac GTP-Binding Proteins/genetics ; Roundabout Proteins

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