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1دورية أكاديمية
المؤلفون: Philipp Weyermann, Robert Dallmann, Josef Magyar, Corinne Anklin, Martina Hufschmid, Judith Dubach-Powell, Isabelle Courdier-Fruh, Marco Henneböhle, Sonja Nordhoff, Cesare Mondadori
المصدر: PLoS ONE, Vol 4, Iss 3, p e4774 (2009)
وصف الملف: electronic resource
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المؤلفون: Jo Alen, Markus Schade, Markus Wagener, Frank Christian, Sonja Nordhoff, Beatrix Merla, Torsten R. Dunkern, Gregor Bahrenberg, Paul Ratcliffe
المصدر: Journal of medicinal chemistry. 62(13)
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Molecular Structure, Crystallography, X-Ray, Ligands, Amides, Alcohol Oxidoreductases, Structure-Activity Relationship, Drug Stability, Drug Discovery, Microsomes, Liver, Molecular Medicine, Humans, Enzyme Inhibitors, Protein Binding
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3
المؤلفون: Sonja Nordhoff, Silke Vaßen, Gregor Bahrenberg, Torsten R. Dunkern, Ilka Schlusche, Katrien Pletinckx
المصدر: Pharmacology Research & Perspectives
مصطلحات موضوعية: Proteasome Endopeptidase Complex, Cell Survival, Down-Regulation, 030226 pharmacology & pharmacy, Peripheral blood mononuclear cell, Bortezomib, Viral Matrix Proteins, immunoproteasome, 03 medical and health sciences, 0302 clinical medicine, Immune system, medicine, Humans, Viability assay, General Pharmacology, Toxicology and Pharmaceutics, Receptor, Cells, Cultured, Chemistry, viability, PSMB8, Original Articles, HLA-DR Antigens, T cell cytokine production, Neurology, 030220 oncology & carcinogenesis, Leukocytes, Mononuclear, Cancer research, Cytokines, Original Article, Cytokine secretion, human immune cells, monocytes, Oligopeptides, Proteasome Inhibitors, medicine.drug
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المؤلفون: Christian Rummey, Meinolf Thiemann, Günther Metz, Sonja Nordhoff
المصدر: Bioorganic & Medicinal Chemistry Letters. 16:1405-1409
مصطلحات موضوعية: Models, Molecular, Molecular model, Stereochemistry, Dipeptidyl Peptidase 4, In silico, Clinical Biochemistry, Drug Evaluation, Preclinical, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, Dipeptidyl peptidase, Inhibitory Concentration 50, Structure-Activity Relationship, Drug Discovery, Protease Inhibitors, Molecular Biology, Dipeptidyl-Peptidase IV Inhibitors, Virtual screening, Binding Sites, biology, Chemistry, Organic Chemistry, Computational Biology, Protein Structure, Tertiary, Molecular Weight, Docking (molecular), Enzyme inhibitor, Drug Design, Benzene derivatives, biology.protein, Molecular Medicine
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المؤلفون: Meinolf Thiemann, Gunther Metz, Sonja Nordhoff, Oliver Hill, Christian Rummey, Silvia Cerezo-Galvez, Paul J. Edwards, Victor G. Matassa, Achim Feurer
المصدر: Bioorganic & Medicinal Chemistry Letters. 16:1744-1748
مصطلحات موضوعية: Models, Molecular, Proline, Molecular model, Swine, Stereochemistry, Dipeptidyl Peptidase 4, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Ring (chemistry), Biochemistry, Chemical synthesis, Structure-Activity Relationship, Phenethylamines, Drug Discovery, Animals, Humans, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Binding Sites, Molecular Structure, biology, Fragment (computer graphics), Organic Chemistry, In vitro, Enzyme, chemistry, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Protein Binding
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المؤلفون: Barbara Silakowski, Helge B. Bode, Taifo Mahmud, Sonja Nordhoff, Mingjie Xu, Rolf Müller, Gerhard Höfle, Reiner M. Kroppenstedt
المصدر: Journal of Biological Chemistry. 277:32768-32774
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Stereochemistry, Biochemistry, chemistry.chemical_compound, Bacterial Proteins, Biosynthesis, Myxobacteria, Leucine, Valine, Valerates, Coenzyme A, Cloning, Molecular, Stigmatella aurantiaca, Molecular Biology, chemistry.chemical_classification, biology, Myxothiazol, Fatty Acids, Fatty acid, DNA, Cell Biology, biology.organism_classification, Amino acid, Thiazoles, Models, Chemical, chemistry, Methacrylates
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46609140c410e8d7810e255014fc791b
https://doi.org/10.1074/jbc.m205222200 -
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المؤلفون: Silvia Cerezo-Galvez, Meinolf Thiemann, Meritxell López-Canet, Holger Deppe, Sonja Nordhoff, Victor G. Matassa, Oliver Hill, Achim Feurer, Christian Rummey, Paul J. Edwards
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:4201-4203
مصطلحات موضوعية: Molecular model, medicine.drug_class, Stereochemistry, Chemistry, Pharmaceutical, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Crystallography, X-Ray, Biochemistry, Chemical synthesis, Dipeptidyl peptidase, Sulfone, Inhibitory Concentration 50, Structure-Activity Relationship, chemistry.chemical_compound, Glucagon-Like Peptide 1, Drug Discovery, medicine, Animals, Molecular Biology, Dipeptidyl peptidase-4, chemistry.chemical_classification, Dipeptidyl-Peptidase IV Inhibitors, Sulfonamides, Aminobutyrates, Organic Chemistry, Hydrogen Bonding, Amides, Rats, Sulfonamide, Enzyme, chemistry, Drug Design, Microsomes, Liver, Molecular Medicine
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المؤلفون: Stephan Bulat, Paul J. Edwards, Victor G. Matassa, Meinolf Thiemann, Oliver Hill, Claudia Rosenbaum, Meritxell López-Canet, Silvia Cerezo-Galvez, Sonja Nordhoff, Barbara Hoffmann-Enger, Christian Rummey, Achim Feurer
المصدر: Bioorganicmedicinal chemistry letters. 19(22)
مصطلحات موضوعية: Stereochemistry, Chemistry, Pharmaceutical, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Chemical synthesis, Dipeptidyl peptidase, Sodium Channels, chemistry.chemical_compound, Structure-Activity Relationship, Animal model, Pharmacokinetics, Amide, Cell Line, Tumor, Drug Discovery, Humans, Hypoglycemic Agents, Protease Inhibitors, Molecular Biology, Dipeptidyl peptidase-4, ADME, Dipeptidyl-Peptidase IV Inhibitors, Aminobutyrates, Organic Chemistry, Metabolic stability, Combinatorial chemistry, Amides, chemistry, Diabetes Mellitus, Type 2, Drug Design, Molecular Medicine, Caco-2 Cells
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المؤلفون: Christian Rummey, Oliver Hill, Meinolf Thiemann, Stephan Bulat, Meritxell López-Canet, Sonja Nordhoff, Achim Feurer, Claudia Rosenbaum, Barbara Hoffmann-Enger, Victor G. Matassa, Paul J. Edwards, Silvia Cerezo-Galvez
المصدر: Bioorganicmedicinal chemistry letters. 19(16)
مصطلحات موضوعية: Pyrrolidines, Hydrocarbons, Fluorinated, Dipeptidyl Peptidase 4, Clinical Biochemistry, Pharmaceutical Science, Administration, Oral, Biochemistry, Dipeptidyl peptidase, Structure-Activity Relationship, Dogs, Pharmacokinetics, Oral administration, Cell Line, Tumor, Drug Discovery, Structure–activity relationship, Animals, Humans, Hypoglycemic Agents, Protease Inhibitors, Molecular Biology, Dipeptidyl peptidase-4, chemistry.chemical_classification, Dipeptidyl-Peptidase IV Inhibitors, Chemistry, Aminobutyrates, Organic Chemistry, Glucagon-like peptide-1, Bioavailability, Rats, Enzyme, Molecular Medicine, Caco-2 Cells