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1دورية أكاديمية
المؤلفون: Anthony W. Partridge, Hung Yi Kristal Kaan, Yu-Chi Juang, Ahmad Sadruddin, Shuhui Lim, Christopher J. Brown, Simon Ng, Dawn Thean, Fernando Ferrer, Charles Johannes, Tsz Ying Yuen, Srinivasaraghavan Kannan, Pietro Aronica, Yaw Sing Tan, Mohan R. Pradhan, Chandra S. Verma, Jerome Hochman, Shiying Chen, Hui Wan, Sookhee Ha, Brad Sherborne, David P. Lane, Tomi K. Sawyer
المصدر: Molecules, Vol 24, Iss 12, p 2292 (2019)
مصطلحات موضوعية: peptide permeability, stapled peptide, macrocyclic peptide, D-amino acid, helix-breaker, Organic chemistry, QD241-441
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Shilpa Pandit, Doug Wisniewski, Joseph C. Santoro, Sookhee Ha, Vijayalakshmi Ramakrishnan, Rose M. Cubbon, Richard T. Cummings, Samuel D. Wright, Carl P. Sparrow, Ayesha Sitlani, Timothy S. Fisher
المصدر: Journal of Lipid Research, Vol 49, Iss 6, Pp 1333-1343 (2008)
مصطلحات موضوعية: proprotein convertase subtilisin/kexin type 9, LDL, LDL receptor, Biochemistry, QD415-436
وصف الملف: electronic resource
Relation: http://www.sciencedirect.com/science/article/pii/S0022227520423776; https://doaj.org/toc/0022-2275
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3
المؤلفون: Simon Ng, Alexander C. Brueckner, Soheila Bahmanjah, Qiaolin Deng, Jennifer M. Johnston, Lan Ge, Ruchia Duggal, Bahanu Habulihaz, Benjamin Barlock, Sookhee Ha, Ahmad Sadruddin, Constance Yeo, Corey Strickland, Andrea Peier, Brian Henry, Edward C. Sherer, Anthony W. Partridge
المصدر: Journal of Medicinal Chemistry. 65:9789-9801
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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4
المؤلفون: Thomas J. Tucker, Nianyu Li, Scott P. Salowe, Harold B. Wood, Danila Branca, Alan S. Bass, Rupesh P. Amin, BethAnn Murphy, Aurash Shahripour, Angela Kerekes, Abbas Walji, Nicole Buist, Jeffrey T. Kuethe, Huaibing He, Rodger Tracy, Kenneth A. Koeplinger, Weixun Wang, Bhavana Bhatt, Candice Alleyne, Sookhee Ha, Douglas G. Johns, Elisabetta Bianchi, Chengwei Wu, Peter Orth, Tjerk Bueters, Yusheng Xiong, Hratch J. Zokian, Michael J. Hafey, Mark W. Embrey, John Higgins
المصدر: Journal of Medicinal Chemistry. 64:16770-16800
مصطلحات موضوعية: chemistry.chemical_classification, Molecular Structure, biology, PCSK9, PCSK9 Inhibitors, Administration, Oral, Biological Availability, Peptide, Pharmacology, Crystallography, X-Ray, Proprotein convertase, Peptides, Cyclic, Rats, Bioavailability, Macaca fascicularis, Structure-Activity Relationship, chemistry, Drug Discovery, biology.protein, Animals, Molecular Medicine, Kexin, Dosing, Antibody, Tricyclic
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5
المؤلفون: Sookhee Ha, Nunzio Sciammetta, Graham Smith, Spencer McMinn, Berengere Sauvagnat, Brett A. Hopkins, Hyelee Lee, Lisa Nogle
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: Library design, chemistry.chemical_classification, 010405 organic chemistry, Chemistry, Organic Chemistry, Peptide, Permeation, 01 natural sciences, Biochemistry, Combinatorial chemistry, Chemical space, 0104 chemical sciences, Ring size, 010404 medicinal & biomolecular chemistry, Permeability (earth sciences), Drug Discovery, Supercritical fluid chromatography, Linker
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6
المؤلفون: Terry Roemer, James R. Tata, Charles G. Garlisi, Mihirbaran Mandal, Christina B. Madsen-Duggan, Ginny D. Ho, Todd Mayhood, Jin Wu, Marc A. Labroli, John P. Caldwell, Alexei V. Buevich, Emma R. Parmee, Hao Wang, Jing Su, Paul Tawa, Sandra Koseoglu, Xiujuan Wen, Sang Ho Lee, Kallol Basu, Payal R. Sheth, Shu-Wei Yang, David G. McLaren, Haifeng Tang, Zheng Tan, Reynalda deJesus, Jenny Liu, Erika Walsh, Sookhee Ha, Christopher M. Tan, Li Xiao, Diane Rindgen, Amy M. Flattery, Debra Mcguinness, Christine Yang, Charles Gill, Paul L. Walsh, Lianzhu Liang
المصدر: Journal of Medicinal Chemistry. 60:3851-3865
مصطلحات موضوعية: Methicillin-Resistant Staphylococcus aureus, 0301 basic medicine, 030106 microbiology, Microbial Sensitivity Tests, Small Molecule Libraries, Mice, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, In vivo, Drug Discovery, Animals, Structure–activity relationship, Solubility, Mice, Inbred BALB C, Teichoic acid, Ligand efficiency, biology, Lipids, Small molecule, Enzyme assay, chemistry, Biochemistry, Lipophilicity, biology.protein, Molecular Medicine, Female
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7
المؤلفون: Hiroshi Nagabukuro, Sean M. Smith, Richard A. Berger, Melissa Costa, Nam Fung Kar, Bart Harper, Karen H. Dingley, Gino Salituro, Liping Wang, Jerry Di Salvo, Scott D. Edmondson, Bing Li, Xiaofang Li, Cheng Zhu, Christopher Moyes, Stephen D. Goble, Sookhee Ha, Mary Struthers, Jeffrey J. Hale, Amanda L. Hurley, Randy R. Miller
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:1094-1098
مصطلحات موضوعية: medicine.medical_specialty, Clinical Biochemistry, Pharmaceutical Science, Adrenergic beta-3 Receptor Agonists, Pharmacology, 030226 pharmacology & pharmacy, 01 natural sciences, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Drug Discovery, medicine, Potency, Structure–activity relationship, Benzamide, Receptor, Molecular Biology, biology, Organic Chemistry, medicine.disease, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Piperazine, Endocrinology, Overactive bladder, chemistry, Norepinephrine transporter, biology.protein, Molecular Medicine
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8
المؤلفون: Shawn P. Walsh, Lee-Yuh Pai, Yuping Zhu, John P. Felix, Caryn Hampton, Xiaoyan Zhou, Melba Hernandez, Brande Thomas-Fowlkes, Richard M. Brochu, Nardos Teumelsan, Gregory J. Kaczorowski, Emma R. Parmee, Maria L. Garcia, Alexander Pasternak, Jinlong Jiang, Sookhee Ha, Sophie Roy, Kathleen A. Sullivan, Haifeng Tang, Lihu Yang, Karen Owens, Reynalda K. de Jesus, Xin Gu, Birgit T. Priest, Barbara Pio, Fa-Xiang Ding, Andrew M. Swensen, Magdalena Alonso-Galicia, Aurash Shahripour, Juliann Ehrhart, Timothy Bailey
المصدر: Bioorganic & Medicinal Chemistry Letters. 26:5695-5702
مصطلحات موضوعية: 0301 basic medicine, QTC PROLONGATION, Clinical Biochemistry, hERG, Pharmaceutical Science, Pharmacology, Biochemistry, Dog model, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Dogs, 0302 clinical medicine, Transcriptional Regulator ERG, Pharmacokinetics, In vivo, Oxazines, Drug Discovery, Animals, Humans, Potassium Channels, Inwardly Rectifying, Molecular Biology, Heart Failure, biology, Chemistry, Organic Chemistry, Macaca mulatta, Small molecule, Diuresis, Piperazine, 030104 developmental biology, 030220 oncology & carcinogenesis, Hypertension, ROMK, biology.protein, Molecular Medicine
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9
المؤلفون: John P. Caldwell, Payal R. Sheth, Jing Su, Terry Roemer, Christopher M. Tan, Todd Mayhood, Charles G. Garlisi, Sandra Koseoglu, Sang Ho Lee, Weidong Pan, Hao Wang, Jianping Pan, Jin Wu, Sookhee Ha, Jing Chen Xiao, Shu-Wei Yang, Christine Yang, Marc A. Labroli
المصدر: Bioorganic & Medicinal Chemistry Letters. 26:4743-4747
مصطلحات موضوعية: Methicillin-Resistant Staphylococcus aureus, 0301 basic medicine, Imipenem, Benzimidazole, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Microbial Sensitivity Tests, medicine.disease_cause, 01 natural sciences, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Biosynthesis, Drug Discovery, medicine, Animals, Molecular Biology, Teichoic acid, 010405 organic chemistry, Organic Chemistry, Bactericidal effect, Methicillin-resistant Staphylococcus aureus, Anti-Bacterial Agents, Rats, 0104 chemical sciences, Teichoic Acids, 030104 developmental biology, chemistry, Molecular Medicine, Benzimidazoles, medicine.drug
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10
المؤلفون: Jennifer M. Johnston, Karen O. Akinsanya, Jason E. Imbriglio, Noel Byrne, Hratch J. Zokian, Sookhee Ha, Scott P. Salowe, Hyewon Youm, George H. Addona, JeanMarie Lisnock, Vijayalakshmi Agnani, Deborah L. Zink, Kake Zhao, Gregory C. Adam, Yusheng Xiong, Brian K. Hubbard, Pravien Abeywickrema, John P. Caldwell, Yongcheng Huang, Jen Baysarowich, Peter Orth, Wonsuk Chang, Juncai Meng, Michael Kavana, James R. Tata, Whitney Lane Petrilli, Rui Liang, Gopal Parthasarathy, Xi Ai, Rachael E. Ford, Zhe Feng, Oksana C. Palyha, Edward DiNunzio, Stephen M. Soisson, Alison M. Strack, Jennifer M. Shipman, Roman S. Erdmann, Zhijian Lu, Sujata Sharma, Jun Lu
مصطلحات موضوعية: Models, Molecular, Thermal shift assay, Serine Proteinase Inhibitors, Clinical Biochemistry, Allosteric regulation, Drug Evaluation, Preclinical, Protein degradation, Ligands, 01 natural sciences, Biochemistry, Small Molecule Libraries, Drug Discovery, Humans, Molecular Biology, Pharmacology, Serine protease, biology, Molecular Structure, 010405 organic chemistry, Chemistry, PCSK9, Proprotein convertase, Ligand (biochemistry), Small molecule, 0104 chemical sciences, Proteolysis, biology.protein, Molecular Medicine, Kexin, Proprotein Convertase 9
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46333ceb2ad6ba949e70430572ed5675
https://doi.org/10.26434/chemrxiv.8800085
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