المؤلفون: Sicong Zhang, Furlow Pw, Nils Halberg, Soong Td, Wu Yg, Mangrum C, Sohail F. Tavazoie, Hani Goodarzi, Olivier Elemento

المصدر: Nature Cell Biology. 17:943-952

مصطلحات موضوعية: Cell Survival, Immunoblotting, Transplantation, Heterologous, Breast Neoplasms, Nerve Tissue Proteins, Stimulation, Mice, SCID, Biology, Connexins, Metastasis, Small Molecule Libraries, Adenosine Triphosphate, Metastatic cell, Mice, Inbred NOD, Cell Line, Tumor, medicine, Animals, Humans, Neoplasm Metastasis, Autocrine signalling, Cells, Cultured, Oligonucleotide Array Sequence Analysis, Mice, Knockout, Microscopy, Confocal, Neovascularization, Pathologic, Cell Biology, Purinergic signalling, Pannexin, medicine.disease, Cell biology, Gene Expression Regulation, Neoplastic, HEK293 Cells, Mutation, RNA Interference, Mechanosensitive channels, Stress, Mechanical, Transcriptome, Disseminated cancer, Interleukin Receptor Common gamma Subunit

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0edddace469232d5645dcaeb8382dcf2
https://doi.org/10.1038/ncb3194

المؤلفون: Bunting KL; Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA; Department of Pharmacology, Weill Cornell Medical College, New York, NY 10065, USA., Soong TD; Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10065, USA., Singh R; Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA; Department of Immunology and Microbial Pathogenesis, Weill Cornell Medical College, New York, NY 10065, USA., Jiang Y; Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA; Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10065, USA; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY 10065, USA., Béguelin W; Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA., Poloway DW; Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA., Swed BL; Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA., Hatzi K; Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA., Reisacher W; Department of Otorhinolaryngology, Weill Cornell Medical College/New York Presbyterian Hospital, New York, NY 10065, USA., Teater M; Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA; Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10065, USA., Elemento O; Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address: ole2001@med.cornell.edu., Melnick AM; Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA; Department of Pharmacology, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address: amm2014@med.cornell.edu.

المصدر: Immunity [Immunity] 2016 Sep 20; Vol. 45 (3), pp. 497-512. Date of Electronic Publication: 2016 Sep 13.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE

مواضيع طبية MeSH: Antibody Affinity/*immunology , B-Lymphocytes/*immunology , Genome/*immunology , Germinal Center/*immunology , Locus Control Region/*immunology, Animals ; Antibody Formation/immunology ; Chromosomes, Human, Pair 3/immunology ; Epigenesis, Genetic/immunology ; Humans ; Immunity, Humoral/immunology ; Mice ; Promoter Regions, Genetic/immunology ; Proto-Oncogene Proteins c-bcl-6/immunology

المؤلفون: Furlow PW; Laboratory of Systems Cancer Biology, Rockefeller University, 1230 York Avenue New York, New York 10065, USA., Zhang S; Laboratory of Systems Cancer Biology, Rockefeller University, 1230 York Avenue New York, New York 10065, USA., Soong TD; HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medical College, Cornell University, New York, New York 10021, USA., Halberg N; Laboratory of Systems Cancer Biology, Rockefeller University, 1230 York Avenue New York, New York 10065, USA., Goodarzi H; Laboratory of Systems Cancer Biology, Rockefeller University, 1230 York Avenue New York, New York 10065, USA., Mangrum C; Laboratory of Systems Cancer Biology, Rockefeller University, 1230 York Avenue New York, New York 10065, USA., Wu YG; Laboratory of Systems Cancer Biology, Rockefeller University, 1230 York Avenue New York, New York 10065, USA., Elemento O; HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medical College, Cornell University, New York, New York 10021, USA., Tavazoie SF; Laboratory of Systems Cancer Biology, Rockefeller University, 1230 York Avenue New York, New York 10065, USA.

المصدر: Nature cell biology [Nat Cell Biol] 2015 Jul; Vol. 17 (7), pp. 943-52. Date of Electronic Publication: 2015 Jun 22.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms/*genetics , Connexins/*genetics , Neovascularization, Pathologic/*genetics , Nerve Tissue Proteins/*genetics, Adenosine Triphosphate/metabolism ; Animals ; Breast Neoplasms/blood supply ; Breast Neoplasms/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/genetics ; Cells, Cultured ; Connexins/antagonists & inhibitors ; Connexins/metabolism ; Gene Expression Regulation, Neoplastic ; HEK293 Cells ; Humans ; Immunoblotting ; Interleukin Receptor Common gamma Subunit/genetics ; Interleukin Receptor Common gamma Subunit/metabolism ; Mice, Inbred NOD ; Mice, Knockout ; Mice, SCID ; Microscopy, Confocal ; Mutation ; Neoplasm Metastasis ; Neovascularization, Pathologic/metabolism ; Neovascularization, Pathologic/prevention & control ; Nerve Tissue Proteins/antagonists & inhibitors ; Nerve Tissue Proteins/metabolism ; Oligonucleotide Array Sequence Analysis ; RNA Interference ; Small Molecule Libraries/pharmacology ; Stress, Mechanical ; Transcriptome ; Transplantation, Heterologous

المؤلفون: Sun XJ; Laboratory of Biochemistry and Molecular Biology, The Rockefeller University, New York, New York 10065, USA., Wang Z, Wang L, Jiang Y, Kost N, Soong TD, Chen WY, Tang Z, Nakadai T, Elemento O, Fischle W, Melnick A, Patel DJ, Nimer SD, Roeder RG

المصدر: Nature [Nature] 2013 Aug 01; Vol. 500 (7460), pp. 93-7. Date of Electronic Publication: 2013 Jun 30.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Cell Transformation, Neoplastic*/genetics, Core Binding Factor Alpha 2 Subunit/*metabolism , Leukemia, Myeloid, Acute/*metabolism , Leukemia, Myeloid, Acute/*pathology , Multiprotein Complexes/*metabolism , Oncogene Proteins, Fusion/*metabolism , Transcription Factors/*metabolism, Amino Acid Motifs ; Amino Acid Sequence ; Animals ; Binding Sites ; Cell Division ; Cell Line, Tumor ; Core Binding Factor Alpha 2 Subunit/chemistry ; Hematopoietic Stem Cells/cytology ; Hematopoietic Stem Cells/metabolism ; Hematopoietic Stem Cells/pathology ; Humans ; Leukemia, Myeloid, Acute/genetics ; Mice ; Models, Molecular ; Molecular Sequence Data ; Multiprotein Complexes/chemistry ; Oncogene Proteins, Fusion/chemistry ; Point Mutation ; Protein Binding ; Protein Multimerization ; Protein Stability ; Protein Structure, Tertiary ; RUNX1 Translocation Partner 1 Protein

المؤلفون: Lu Y; Department of Physiology and Biophysics, Weill Cornell Medical College, Cornell University, New York, New York, United States of America., Soong TD, Elemento O

المصدر: PloS one [PLoS One] 2013 May 06; Vol. 8 (5), pp. e63056. Date of Electronic Publication: 2013 May 06 (Print Publication: 2013).

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Microsatellite Instability*, Colonic Neoplasms/*genetics, Colonic Neoplasms/diagnosis ; Colonic Neoplasms/metabolism ; DNA Mismatch Repair ; Genetic Markers ; HCT116 Cells ; High-Throughput Nucleotide Sequencing ; Humans ; INDEL Mutation ; Molecular Diagnostic Techniques ; Sequence Analysis, DNA ; Transcriptome

المؤلفون: Baca SC; Harvard Medical School, Boston, MA 02115, USA., Prandi D, Lawrence MS, Mosquera JM, Romanel A, Drier Y, Park K, Kitabayashi N, MacDonald TY, Ghandi M, Van Allen E, Kryukov GV, Sboner A, Theurillat JP, Soong TD, Nickerson E, Auclair D, Tewari A, Beltran H, Onofrio RC, Boysen G, Guiducci C, Barbieri CE, Cibulskis K, Sivachenko A, Carter SL, Saksena G, Voet D, Ramos AH, Winckler W, Cipicchio M, Ardlie K, Kantoff PW, Berger MF, Gabriel SB, Golub TR, Meyerson M, Lander ES, Elemento O, Getz G, Demichelis F, Rubin MA, Garraway LA

المصدر: Cell [Cell] 2013 Apr 25; Vol. 153 (3), pp. 666-77.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: Chromosome Aberrations* , Gene Expression Regulation, Neoplastic* , Genome, Human*, Prostatic Neoplasms/*genetics, Adenocarcinoma/genetics ; Adenocarcinoma/pathology ; Cohort Studies ; Genome-Wide Association Study ; Humans ; Male ; Neuroendocrine Tumors/genetics ; Neuroendocrine Tumors/pathology ; Prostatic Neoplasms/pathology

المؤلفون: Rickman DS; Department of Pathology and Laboratory Medicine, HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10065, USA., Soong TD, Moss B, Mosquera JM, Dlabal J, Terry S, MacDonald TY, Tripodi J, Bunting K, Najfeld V, Demichelis F, Melnick AM, Elemento O, Rubin MA

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2012 Jun 05; Vol. 109 (23), pp. 9083-8. Date of Electronic Publication: 2012 May 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Nucleic Acid Conformation*, Chromatin Assembly and Disassembly/*genetics , Trans-Activators/*metabolism, Base Sequence ; Cell Line ; Chromatin Immunoprecipitation ; DNA Primers/genetics ; Flow Cytometry ; High-Throughput Nucleotide Sequencing ; Humans ; In Situ Hybridization, Fluorescence ; Karyotyping ; Molecular Sequence Data ; Reverse Transcriptase Polymerase Chain Reaction ; Transcriptional Regulator ERG

المؤلفون: Demichelis F; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065, USA. demichelis@science.unitn.it, Setlur SR, Banerjee S, Chakravarty D, Chen JY, Chen CX, Huang J, Beltran H, Oldridge DA, Kitabayashi N, Stenzel B, Schaefer G, Horninger W, Bektic J, Chinnaiyan AM, Goldenberg S, Siddiqui J, Regan MM, Kearney M, Soong TD, Rickman DS, Elemento O, Wei JT, Scherr DS, Sanda MA, Bartsch G, Lee C, Klocker H, Rubin MA

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2012 Apr 24; Vol. 109 (17), pp. 6686-91. Date of Electronic Publication: 2012 Apr 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Validation Study

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Chromosomes, Human, Pair 12* , Chromosomes, Human, Pair 15* , Gene Dosage* , Genetic Predisposition to Disease*, Prostatic Neoplasms/*genetics, Case-Control Studies ; Cell Line, Tumor ; Cell Proliferation ; Cohort Studies ; Humans ; Male ; Polymerase Chain Reaction ; Polymorphism, Single Nucleotide ; Prostatic Neoplasms/pathology

المؤلفون: Jiang Y; HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine and Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York, United States of America., Soong TD, Wang L, Melnick AM, Elemento O

المصدر: PloS one [PLoS One] 2012; Vol. 7 (7), pp. e40332. Date of Electronic Publication: 2012 Jul 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Genes, Neoplasm/*genetics , Genome, Human/*genetics , Lymphoma/*genetics , Somatic Hypermutation, Immunoglobulin/*genetics, B-Lymphocytes/metabolism ; B-Lymphocytes/pathology ; Cell Differentiation/genetics ; Cell Line, Tumor ; Chromatin Immunoprecipitation ; Gene Expression Regulation, Neoplastic ; Genes, Regulator/genetics ; Histones/metabolism ; Humans ; Lymphoma/immunology ; Lymphoma/pathology ; Lymphoma, Large B-Cell, Diffuse/genetics ; Lymphoma, Large B-Cell, Diffuse/immunology ; Lymphoma, Large B-Cell, Diffuse/pathology ; Methylation ; Polymorphism, Single Nucleotide/genetics ; Promoter Regions, Genetic/genetics ; Sequence Analysis, DNA