المؤلفون: Jennifer P. Morton, Sylvie Martel, Cassandre Caligaris, Isabelle Goddard, Julie Guillermet, Victoire Cardot, Emilie Servoz, Laurent Bartholin, David F. Vincent, Amélie Colombe, Anne Couvelard, Vinciane Rebours, Isabelle Treilleux, Karam Yacoub, Elodie Roger, Johann Gout, Pierre Dubus, Julie Valantin, Bastien Kaniewski, Ulrich Valcourt, Nicolas Gadot, Roxane M. Pommier, Sophie Goddard-Léon, Célia Cintas, Owen J. Sansom, Nicolas Chuvin, Lindsay B. Alcaraz, Stéphanie Sentis

المساهمون: Centre de Recherche en Cancérologie de Lyon (CRCL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre Léon Bérard [Lyon]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Reproduction et développement des plantes (RDP), École normale supérieure - Lyon (ENS Lyon)-Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Université d'Artois (UA), Oncogénèse et progression tumorale, Centre Léon Bérard [Lyon]-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de Recherches en Cancérologie de Toulouse (CRCT), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Beatson Institute for Cancer Research [Glasgow, Royaume-Uni], Département d'Anatomo-Pathologie [Hôpital Bichat], AP-HP - Hôpital Bichat - Claude Bernard [Paris], Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Beatson Institute for Cancer Research, Beatson institute for cancer research, Histologie et Pathologie Moléculaire des Tumeurs, Université Bordeaux Segalen - Bordeaux 2-EA 2406, INSERM U897, University of Bordeaux, France, Centre de Recherche en Cancérologie de Lyon (UNICANCER/CRCL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), The Beatson Institute for Cancer Research, University of Glasgow, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), École normale supérieure de Lyon (ENS de Lyon)-Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Philadelphia, PA : American Gastroenterological Association, [2015]-, 2017, 4 (2), pp.263-282. ⟨10.1016/j.jcmgh.2017.05.005⟩
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 2, Pp 263-282 (2017)
Cellular and Molecular Gastroenterology and Hepatology, 2017, 4 (2), pp.263-282. ⟨10.1016/j.jcmgh.2017.05.005⟩

مصطلحات موضوعية: 0301 basic medicine, Hepatology, Gastroenterology, Pancreatic Intraepithelial Neoplasia, Pancreas Cancer TGFβ Acinar-to-Ductal Metaplasia KRASG12D, [SDV.CAN]Life Sciences [q-bio]/Cancer, SMAD, Transforming growth factor beta, Biology, medicine.disease, medicine.disease_cause, 3. Good health, 03 medical and health sciences, 030104 developmental biology, medicine.anatomical_structure, Pancreatic tumor, Pancreatic cancer, medicine, biology.protein, Cancer research, lcsh:Diseases of the digestive system. Gastroenterology, KRAS, lcsh:RC799-869, Pancreas, Carcinogenesis

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732e1f91c6e88e1fd755fc3ec9f403b2
https://doi.org/10.1016/j.jcmgh.2017.05.005

المؤلفون: Nicolas, Chuvin, David F, Vincent, Roxane M, Pommier, Lindsay B, Alcaraz, Johann, Gout, Cassandre, Caligaris, Karam, Yacoub, Victoire, Cardot, Elodie, Roger, Bastien, Kaniewski, Sylvie, Martel, Celia, Cintas, Sophie, Goddard-Léon, Amélie, Colombe, Julie, Valantin, Nicolas, Gadot, Emilie, Servoz, Jennifer, Morton, Isabelle, Goddard, Anne, Couvelard, Vinciane, Rebours, Julie, Guillermet, Owen J, Sansom, Isabelle, Treilleux, Ulrich, Valcourt, Stéphanie, Sentis, Pierre, Dubus, Laurent, Bartholin

المصدر: Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: Acinar-to-Ductal Metaplasia, PanIN, pancreatic intraepithelial neoplasia, PBS, phosphate-buffered saline, PDA, pancreatic ductal adenocarcinoma, AFI, acinar fatty infiltration, TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling, ADM, acinar-to-ductal metaplasia, TGFβ, TGFβ, transforming growth factor beta, KRASG12D, RT-qPCR, reverse transcription quantitative polymerase chain reaction, Pancreas, EMT, epithelial-to-mesenchymal transition, Original Research, Cancer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::20de94547deb32ea06f9db48c59a579c
https://pubmed.ncbi.nlm.nih.gov/28752115

المؤلفون: Doriane Ripoche, Philippe Bertolino, Amélie Colombe, Laurent Bartholin, Ulrich Valcourt, Isabelle Treilleux, Richard Tomasini, Marlène Dufresne, Sophie Goddard-Léon, David F. Vincent, Roxane M. Pommier, Johann Gout

المصدر: Pancreatology. 13:191-195

مصطلحات موضوعية: endocrine system, medicine.medical_specialty, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Adenocarcinoma, Biology, medicine.disease_cause, Glucagon, Proto-Oncogene Proteins p21(ras), Islets of Langerhans, Mice, Internal medicine, Carcinoma, medicine, Animals, Endocrine system, Pancreas, Homeodomain Proteins, geography, geography.geographical_feature_category, Hepatology, Gastroenterology, Hyperplasia, medicine.disease, Islet, digestive system diseases, Pancreatic Neoplasms, medicine.anatomical_structure, Endocrinology, Disease Progression, Trans-Activators, Cancer research, PDX1, KRAS, Precancerous Conditions, Carcinoma, Pancreatic Ductal

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba06cc0d3026362adc304e6e50a9a55
https://doi.org/10.1016/j.pan.2013.02.001

المؤلفون: Lucien Frappart, Christine Carreira, Christelle Seigne, Thomas Bachelot, Magdalena Auret, Chang Xian Zhang, Fouzia Assade, Emilie Lavergne, Rémy Bonnavion, Isabelle Treilleux, Sylvie Mazoyer, Amandine Garcia, Sophie Goddard-Léon, Sylvie Chabaud, Jieli Lu

المصدر: The Journal of Pathology. 229:546-558

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, endocrine system, medicine.medical_specialty, Intraepithelial neoplasia, endocrine system diseases, Transgene, Mutant, Biology, medicine.disease, Prolactin, Pathology and Forensic Medicine, Endocrinology, Internal medicine, medicine, Endocrine system, MEN1, Multiple endocrine neoplasia, Prolactinoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4d6bdcd543b0dc49c5e7ef4acb790f3b
https://doi.org/10.1002/path.4146

المؤلفون: Solène Perez, Sophie Goddard-Léon, Vanessa Arfi, Anne Claire Doffin, Daniel Olive, Isabelle Treilleux, Christelle Faure, Alain Puisieux, Jean-Yves Blay, Isabelle Ray-Coquard, Nathalie Bendriss-Vermare, Christophe Caux, Nicolas Pasqual, Thomas Bachelot, Isabelle Durand, Christine Ménétrier-Caux, Cathy Biota, Michael Gobert

المصدر: Cancer Research. 69:2000-2009

مصطلحات موضوعية: Antigens, Differentiation, T-Lymphocyte, Cancer Research, Receptors, CCR4, CD3, Breast Neoplasms, chemical and pharmacologic phenomena, Biology, Lymphocyte Activation, T-Lymphocytes, Regulatory, Inducible T-Cell Co-Stimulator Protein, Antigen, Cell Movement, Humans, IL-2 receptor, Interleukin-7 receptor, Cell Aggregation, Chemokine CCL22, FOXP3, Forkhead Transcription Factors, hemic and immune systems, Cell aggregation, Ki-67 Antigen, Oncology, Tumor progression, Immunology, biology.protein, CD8

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05fbdd479ec52e643d4dbce83e67450
https://doi.org/10.1158/0008-5472.can-08-2360

المؤلفون: Branka Horvat, Cyril Berthet, C Garcia, Ruth Rimokh, Sophie Goddard-Léon, Farhan S. Cyprian, David F. Vincent, Isabelle Treilleux, Laurent Bartholin, Julien C. Marie, Sylvie Martel

المصدر: genesis. 46:724-731

مصطلحات موضوعية: Male, Genetically modified mouse, T-Lymphocytes, Transgene, Receptor, Transforming Growth Factor-beta Type I, SMAD, Protein Serine-Threonine Kinases, Biology, Lymphocyte Activation, Mice, Endocrinology, Downregulation and upregulation, Transforming Growth Factor beta, Genetics, Animals, Humans, Enhancer, Receptor, Mice, Knockout, Cell Biology, Transforming growth factor beta, Molecular biology, Cell biology, Gene Expression Regulation, biology.protein, Female, Receptors, Transforming Growth Factor beta, Signal Transduction, Transforming growth factor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9d45063179227cc1e07d3173aa9969
https://doi.org/10.1002/dvg.20425

المؤلفون: Anne-Sophie Ay, Stéphanie Joguet, Laurent Bartholin, Diane Razanajaona, Isabelle Treilleux, Ruth Rimokh, Sophie Goddard-Léon

المصدر: Cancer Research. 67:7223-7229

مصطلحات موضوعية: Follistatin, Cancer Research, medicine.medical_specialty, Follistatin-Related Proteins, Blotting, Western, Breast Neoplasms, Enzyme-Linked Immunosorbent Assay, Endogeny, Smad2 Protein, Biology, Transfection, Transforming Growth Factor beta1, chemistry.chemical_compound, Internal medicine, Tumor Cells, Cultured, medicine, Humans, Gene silencing, Gene Silencing, Phosphorylation, RNA, Small Interfering, Activin type 2 receptors, Cell Proliferation, Reverse Transcriptase Polymerase Chain Reaction, Cell growth, Carcinoma, Ductal, Breast, Activin receptor, Activins, Cell biology, Endocrinology, Oncology, chemistry, Growth inhibition, ACVR2B, Transforming growth factor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2573092fef142db2ec61cfc6ea4d0ba7
https://doi.org/10.1158/0008-5472.can-07-0805

المؤلفون: Julien Faget, Catherine Biota, Sophie Goddard-Léon, Isabelle Treilleux, Nathalie Bendriss-Vermare, Emilie Lavergne, Christine Ménétrier-Caux, Thomas Bachelot, Isabelle Durand, Michael Gobert, Sylvie Chabaud, Christophe Caux, Daniel Olive, Jean-Yves Blay

المصدر: Cancer research. 72(23)

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Cancer Research, T cell, medicine.medical_treatment, CD3, chemical and pharmacologic phenomena, Breast Neoplasms, Lymphocyte Activation, T-Lymphocytes, Regulatory, Inducible T-Cell Co-Stimulator Protein, Inducible T-Cell Co-Stimulator Ligand, Interferon-gamma, Breast cancer, T-Lymphocyte Subsets, medicine, Humans, Secretion, Retrospective Studies, biology, CD28, Antibodies, Monoclonal, hemic and immune systems, Immunosuppression, Dendritic Cells, medicine.disease, Immunohistochemistry, Interleukin-10, ICOS LIGAND, medicine.anatomical_structure, Oncology, Immunology, biology.protein, Disease Progression, Female, Antibody

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f078d9046d0fcddf098002e4dac0db3
https://pubmed.ncbi.nlm.nih.gov/23026134

المؤلفون: Jean-Yves Blay, Agathe Bajard, Julien Faget, Sana Intidhar Labidi-Galy, Nadège Goutagny, Christophe Caux, Christine Ménétrier-Caux, Nathalie Bendriss-Vermare, Vanja Sisirak, Isabelle Treilleux, Isabelle Le Mercier, Gaelle Poyet, Nelly Vey, Alain Puisieux, Sophie Goddard-Léon, Sarah Renaudineau, Thomas Bachelot, Isabelle Durand, Isabelle Puisieux, Michael Gobert

المصدر: Cancer research. 72(20)

مصطلحات موضوعية: Cancer Research, Mitotic index, Regulatory T cell, Breast Neoplasms, Biology, T-Lymphocytes, Regulatory, Immune tolerance, Flow cytometry, Immune system, Breast cancer, In vivo, medicine, Tumor Microenvironment, Humans, medicine.diagnostic_test, FOXP3, Interferon-alpha, hemic and immune systems, Dendritic Cells, medicine.disease, Immunohistochemistry, medicine.anatomical_structure, Oncology, Immunology, Disease Progression, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dbe39ea7343f7f3da00fe3863e71fce
https://pubmed.ncbi.nlm.nih.gov/22836755

المؤلفون: Muriel Le Romancer, Laura Corbo, Sylvie Chabaud, Katia Bouchekioua-Bouzaghou, Isabelle Treilleux, Olivier Tredan, Coralie Poulard, Emilie Lavergne, Sophie Goddard-Léon

المصدر: EMBO Molecular Medicine

مصطلحات موضوعية: Adult, Breast Neoplasms, Proximity ligation assay, Biology, PI3K, Phosphatidylinositol 3-Kinases, Breast cancer, breast cancer, Cell Line, Tumor, medicine, Humans, Src tyrosine kinase, Receptor, skin and connective tissue diseases, Protein kinase B, PI3K/AKT/mTOR pathway, Research Articles, Aged, Aged, 80 and over, oestrogen receptors, Estrogen Receptor alpha, Estrogens, Middle Aged, medicine.disease, Survival Analysis, arginine methylation, Immunology, Cancer research, Molecular Medicine, Female, Signal transduction, Estrogen receptor alpha, Proto-Oncogene Proteins c-akt, Proto-oncogene tyrosine-protein kinase Src, Protein Binding, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c89c533a58c9e21edfc4d1c5b4ffb587
https://pubmed.ncbi.nlm.nih.gov/23065768