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1دورية أكاديمية
المصدر: Frontiers in Pharmacology, Vol 13 (2022)
مصطلحات موضوعية: GPCR, Alzheimer’s disease, neurodegenerative disease, neuroinflammation, G protein coupled receptors, drug discovery, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Emma T. van der Westhuizen, K. H. Christopher Choy, Celine Valant, Simon McKenzie-Nickson, Sophie J. Bradley, Andrew B. Tobin, Patrick M. Sexton, Arthur Christopoulos
المصدر: Frontiers in Pharmacology, Vol 11 (2021)
مصطلحات موضوعية: muscarinic receptor, allosteric modulation, Alzheimer’s disease, schizophrenia, biased agonism, biased allostery, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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المؤلفون: Louis Dwomoh, Mario Rossi, Miriam Scarpa, Elham Khajehali, Colin Molloy, Pawel Herzyk, Shailesh N. Mistry, Andrew R. Bottrill, Patrick M. Sexton, Arthur Christopoulos, Jeffrey Conn, Craig W. Lindsley, Sophie J. Bradley, Andrew B. Tobin
المصدر: Science Signaling. 15
مصطلحات موضوعية: Cell Biology, Molecular Biology, Biochemistry
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c168e561d75a13f908e050a3542ed50
https://doi.org/10.1126/scisignal.abm3720 -
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المؤلفون: Louis, Dwomoh, Mario, Rossi, Miriam, Scarpa, Elham, Khajehali, Colin, Molloy, Pawel, Herzyk, Shailesh N, Mistry, Andrew R, Bottrill, Patrick M, Sexton, Arthur, Christopoulos, Jeffrey, Conn, Craig W, Lindsley, Sophie J, Bradley, Andrew B, Tobin
المصدر: Science signaling. 15(760)
مصطلحات موضوعية: Proteomics, Mice, Prions, Alzheimer Disease, Receptor, Muscarinic M1, Humans, Animals, Neurodegenerative Diseases, Pathology, Molecular, Prion Diseases
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::ee6615158b043fc9f0ea7d2b16efa605
https://pubmed.ncbi.nlm.nih.gov/36378750 -
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المؤلفون: Sara Marsango, Laura Jenkins, John D. Pediani, Sophie J. Bradley, Richard J. Ward, Sarah Hesse, Gabriel Biener, Michael R. Stoneman, Andrew B. Tobin, Valerica Raicu, Graeme Milligan
المصدر: Proceedings of the National Academy of Sciences. 119
مصطلحات موضوعية: Multidisciplinary
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ff0659603401b1165c42bc55f0eb67fe
https://doi.org/10.1073/pnas.2201103119 -
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المؤلفون: Sara, Marsango, Laura, Jenkins, John D, Pediani, Sophie J, Bradley, Richard J, Ward, Sarah, Hesse, Gabriel, Biener, Michael R, Stoneman, Andrew B, Tobin, Valerica, Raicu, Graeme, Milligan
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 119(24)
مصطلحات موضوعية: Cerebral Cortex, Mice, Knockout, Neurons, Mice, Green Fluorescent Proteins, Optical Imaging, Receptor, Muscarinic M1, Animals, Ligands, Hippocampus
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::8744dd902f1964ff4046e82f97e88068
https://pubmed.ncbi.nlm.nih.gov/35671422 -
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المؤلفون: Andrew B. Tobin, Gerard R. Dawson, Patrick M. Sexton, Nathan Robertson, Sophie J. Bradley, Francesca Perini, Arthur Christopoulos, James C. Errey, Barry John Teobald, John Francis William Deakin, Lisa M. Broad, Jan Liptrot, Christopher J. Langmead, K.A. Bennett, Mary Vinson, Pradeep J. Nathan, Colin Molloy, Robert M. Cooke, Edward Hurrell, Michael Browning, Krzysztof Okrasa, Jason M Brown, Giulio Mattedi, Alastair J. H. Brown, David M. Cross, Greg J. Osborne, Julie E. Cansfield, Ali Jazayeri, Christoffer Bundgaard, Stephen R. Morairty, J.C. Patel, Fiona H. Marshall, Brian D. Hudson, Prakash Rucktooa, Robert T. Smith, Keith G. Phillips, Louis Dwomoh, Chris de Graaf, Malcolm Peter Weir, Julie Warneck, Giles A. Brown, Mark Pickworth, Benjamin G. Tehan, Tim Tasker, Anushka V. Goonawardena, Miles Congreve, João M. Dias, Shahram Shahabi
مصطلحات موضوعية: Agonist, medicine.drug_class, Neurodegeneration, Muscarinic acetylcholine receptor M1, Biology, medicine.disease, Acetylcholinesterase, General Biochemistry, Genetics and Molecular Biology, chemistry.chemical_compound, chemistry, Muscarinic acetylcholine receptor, medicine, Cholinergic, Receptor, Neuroscience, Acetylcholine, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b008b7a3c01abe25b8e63fdab465cc4
https://ora.ox.ac.uk/objects/uuid:fc10e298-8675-4411-9af5-3cfd801f0d78 -
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المؤلفون: Arthur Christopoulos, Colin Molloy, Lisa Finlayson, Emma T van der Westhuizen, Celine Valant, Craig W. Lindsley, Sophie J. Bradley, Patrick M. Sexton, Elham Khajehali, Andrew B. Tobin
المصدر: ACS Chemical Neuroscience. 11:4270-4279
مصطلحات موضوعية: Agonist, Allosteric modulator, Physiology, medicine.drug_class, Chemistry, Cognitive Neuroscience, Allosteric regulation, Cell Biology, General Medicine, Ligand (biochemistry), Biochemistry, 3. Good health, Cell biology, Muscarinic acetylcholine receptor, medicine, Receptor, Endogenous agonist, Acetylcholine, medicine.drug
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المؤلفون: Neil M. Nathanson, Jürgen Wess, Rudolf Hammer, R. A. John Challiss, Richard M. Eglen, Fred Mitchelson, David Brown, Sophie J. Bradley, Celine Valant, Heinz Kilbinger, Chris Langmead, Frederick J. Ehlert, Andrew B. Tobin, Noel J. Buckley, Ernst Mutschler, Günter Lambrecht, Arthur Christopoulos, David M. Thal, Roy D. Schwarz, Nigel J. M. Birdsall, Christian C. Felder
المصدر: IUPHAR/BPS Guide to Pharmacology CITE. 2021
مصطلحات موضوعية: Bradycardia, Atropine, Pilocarpine, Chemistry, Muscarinic acetylcholine receptor, medicine, Pharmacology, medicine.symptom, Muscarinic Agents, Endogenous agonist, Acetylcholine, medicine.drug, Acetylcholine receptor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::21748271f1e349fb133f34951200f47b
https://doi.org/10.2218/gtopdb/f2/2021.3 -
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المؤلفون: Sophie J. Bradley, Shailesh N. Mistry, Patrick M. Sexton, Elham Khajehali, Colin Molloy, Miriam Scarpa, Andrew R. Bottrill, P. Jeffery Conn, Pawel Herzyk, Mario Rossi, Arthur Christopoulos, Craig W. Lindsley, Louis Dwomoh, Andrew B. Tobin
مصطلحات موضوعية: Allosteric modulator, Neurodegeneration, Allosteric regulation, Muscarinic acetylcholine receptor, medicine, Protein folding, Disease, Biology, Receptor, medicine.disease, Neuroscience, Neuroinflammation
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::68ffd93afdb37e9547c32a948682b7d5
https://doi.org/10.1101/2021.07.30.454298