لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

المؤلفون: Bartl S; HD Immune, Vienna, Austria. Electronic address: S.bartl@HDImmune.com., Xie Y; University of Central Florida, Burnett School of Biomedical Sciences, Orlando, FL, United States of America; University of British Columbia, Centre for Molecular Medicine and Therapeutics, Vancouver, Canada., Potluri N; University of Central Florida, Burnett School of Biomedical Sciences, Orlando, FL, United States of America., Kesineni R; University of Central Florida, Burnett School of Biomedical Sciences, Orlando, FL, United States of America., Hencak K; University of Central Florida, Burnett School of Biomedical Sciences, Orlando, FL, United States of America., Cengio LD; University of British Columbia, Centre for Molecular Medicine and Therapeutics, Vancouver, Canada., Balazs K; AFFiRiS AG, Vienna, Austria., Oueslati A; Centre de recherche du CHU - Universite Laval, Quebec, Canada., Parth M; AFFiRiS AG, Vienna, Austria., Salhat N; AFFiRiS AG, Vienna, Austria., Siddu A; Centre de recherche du CHU - Universite Laval, Quebec, Canada., Smrzka O; AFFiRiS AG, Vienna, Austria., Cicchetti F; Centre de recherche du CHU - Universite Laval, Quebec, Canada., Staffler G; AFFiRiS AG, Vienna, Austria., Hayden MR; University of British Columbia, Centre for Molecular Medicine and Therapeutics, Vancouver, Canada., Southwell AL; University of Central Florida, Burnett School of Biomedical Sciences, Orlando, FL, United States of America. Electronic address: amber.southwell@ucf.edu.

المصدر: Neurobiology of disease [Neurobiol Dis] 2024 Apr; Vol. 193, pp. 106444. Date of Electronic Publication: 2024 Feb 24.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Bartl S; HD Immune, Vienna, Austria. Electronic address: S.bartl@HDImmune.com., Xie Y; University of Central Florida, Burnett School of Biomedical Sciences, Orlando, FL, United States of America; University of British Columbia, Centre for Molecular Medicine and Therapeutics, Vancouver, Canada., Potluri N; University of Central Florida, Burnett School of Biomedical Sciences, Orlando, FL, United States of America., Kesineni R; University of Central Florida, Burnett School of Biomedical Sciences, Orlando, FL, United States of America., Hencak K; University of Central Florida, Burnett School of Biomedical Sciences, Orlando, FL, United States of America., Cengio LD; University of British Columbia, Centre for Molecular Medicine and Therapeutics, Vancouver, Canada., Balazs K; AFFiRiS AG, Vienna, Austria., Oueslati A; Centre de recherche du CHU - Université Laval, Québec, Canada., Parth M; AFFiRiS AG, Vienna, Austria., Salhat N; AFFiRiS AG, Vienna, Austria., Siddu A; Centre de recherche du CHU - Université Laval, Québec, Canada., Smrzka O; AFFiRiS AG, Vienna, Austria., Cicchetti F; Centre de recherche du CHU - Université Laval, Québec, Canada., Straffler G; AFFiRiS AG, Vienna, Austria., Hayden MR; University of British Columbia, Centre for Molecular Medicine and Therapeutics, Vancouver, Canada., Southwell AL; University of Central Florida, Burnett School of Biomedical Sciences, Orlando, FL, United States of America. Electronic address: amber.southwell@ucf.edu.

المصدر: Neurobiology of disease [Neurobiol Dis] 2024 Jan; Vol. 190, pp. 106376. Date of Electronic Publication: 2023 Dec 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

مواضيع طبية MeSH: Huntington Disease*/metabolism, Mice ; Animals ; Mice, Transgenic ; Nerve Tissue Proteins/metabolism ; Nuclear Proteins/metabolism ; Huntingtin Protein/genetics ; Immunotherapy ; Disease Models, Animal ; Antibodies, Monoclonal/pharmacology ; Antibodies, Monoclonal/therapeutic use ; Disease Progression

المؤلفون: Caron NS; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada. Electronic address: ncaron@cmmt.ubc.ca., Banos R; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32827, USA. Electronic address: raul.banos@ucf.edu., Aly AE; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada. Electronic address: aealy@cmmt.ubc.ca., Xie Y; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32827, USA. Electronic address: yuanyun.xie@ucf.edu., Ko S; Centre for Molecular Medicine and Therapeutics, Vancouver, BC V5Z 4H4, Canada. Electronic address: yko@cmmt.ubc.ca., Potluri N; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32827, USA. Electronic address: nalini.potluri@ucf.edu., Anderson C; Centre for Molecular Medicine and Therapeutics, Vancouver, BC V5Z 4H4, Canada. Electronic address: canderson@cmmt.ubc.ca., Black HF; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada. Electronic address: hfindlayblack@cmmt.ubc.ca., Anderson LM; Centre for Molecular Medicine and Therapeutics, Vancouver, BC V5Z 4H4, Canada. Electronic address: landerson@cmmt.ubc.ca., Gordon B; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32827, USA. Electronic address: benjamin.gordon@ucf.edu., Southwell AL; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32827, USA. Electronic address: amber.southwell@ucf.edu., Hayden MR; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada. Electronic address: mrh@cmmt.ubc.ca.

المصدر: Neurobiology of disease [Neurobiol Dis] 2022 May; Vol. 166, pp. 105652. Date of Electronic Publication: 2022 Feb 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

مواضيع طبية MeSH: Huntington Disease*/metabolism , Neurodegenerative Diseases*/genetics, Animals ; Biomarkers/cerebrospinal fluid ; Disease Models, Animal ; Huntingtin Protein/genetics ; Huntingtin Protein/metabolism ; Mice ; Mice, Transgenic ; Trinucleotide Repeat Expansion/genetics

المؤلفون: Rook ME; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, 32827, USA. amber.southwell@ucf.edu., Southwell AL; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, 32827, USA.

المصدر: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy [BioDrugs] 2022 Mar; Vol. 36 (2), pp. 105-119. Date of Electronic Publication: 2022 Mar 07.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9705305 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-190X (Electronic) Linking ISSN: 11738804 NLM ISO Abbreviation: BioDrugs Subsets: MEDLINE

مواضيع طبية MeSH: Huntington Disease*/drug therapy , Huntington Disease*/genetics, Humans ; Huntingtin Protein/genetics ; Huntingtin Protein/metabolism ; Oligonucleotides, Antisense/pharmacology ; Oligonucleotides, Antisense/therapeutic use ; Prospective Studies

المؤلفون: Ravalia AS; Division of Biomedical Science, Faculty of Medicine, Memorial University, St. John's, NL A1B 3V6, Canada., Lau J; Division of Biomedical Science, Faculty of Medicine, Memorial University, St. John's, NL A1B 3V6, Canada., Barron JC; Division of Biomedical Science, Faculty of Medicine, Memorial University, St. John's, NL A1B 3V6, Canada., Purchase SLM; Division of Biomedical Science, Faculty of Medicine, Memorial University, St. John's, NL A1B 3V6, Canada., Southwell AL; University of Central Florida, College of Medicine, Burnett School of Biomedical Sciences, Orlando, FL, USA., Hayden MR; Centre for Molecular Medicine and Therapeutics, Department of Medical Genetics, University of British Columbia, Vancouver, Canada., Nafar F; Division of Biomedical Science, Faculty of Medicine, Memorial University, St. John's, NL A1B 3V6, Canada., Parsons MP; Division of Biomedical Science, Faculty of Medicine, Memorial University, St. John's, NL A1B 3V6, Canada. Electronic address: matthew.parsons@med.mun.ca.

المصدر: Neurobiology of disease [Neurobiol Dis] 2021 May; Vol. 152, pp. 105293. Date of Electronic Publication: 2021 Feb 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

مواضيع طبية MeSH: Hippocampus/*physiopathology , Huntington Disease/*physiopathology , Receptors, AMPA/*ultrastructure , Synapses/*pathology , Synapses/*ultrastructure, Animals ; Female ; Hippocampus/pathology ; Hippocampus/ultrastructure ; Huntington Disease/pathology ; Male ; Mice ; Neuronal Plasticity/physiology ; Prodromal Symptoms ; Receptors, AMPA/metabolism

المؤلفون: Caron NS; Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia V5Z 4H4, Canada., Banos R; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida 32828., Yanick C; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida 32828., Aly AE; Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia V5Z 4H4, Canada., Byrne LM; UCL Huntington's Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom., Smith ED; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida 32828., Xie Y; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida 32828., Smith SEP; Seattle Children's Research Institute, Center for Integrative Brain Research, Seattle, Washington 98101., Potluri N; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida 32828., Findlay Black H; Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia V5Z 4H4, Canada., Casal L; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia V5Z 4H4, Canada., Ko S; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia V5Z 4H4, Canada., Cheung D; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia V5Z 4H4, Canada., Kim H; Department of Biological Sciences, KAIST, Daejeon, Korea, 34141., Seong IS; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114., Wild EJ; UCL Huntington's Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom., Song JJ; Department of Biological Sciences, KAIST, Daejeon, Korea, 34141., Hayden MR; Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia V5Z 4H4, Canada amber.southwell@ucf.edu mrh@cmmt.ubc.ca., Southwell AL; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida 32828 amber.southwell@ucf.edu mrh@cmmt.ubc.ca.

المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2021 Jan 27; Vol. 41 (4), pp. 780-796. Date of Electronic Publication: 2020 Dec 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Brain Chemistry*, Huntingtin Protein/*cerebrospinal fluid , Huntington Disease/*cerebrospinal fluid, Animals ; Astrocytes/metabolism ; Biomarkers/cerebrospinal fluid ; Female ; Glymphatic System/metabolism ; Humans ; Huntingtin Protein/genetics ; Huntington Disease/genetics ; Male ; Mice ; Mice, Transgenic ; Mutation ; Neurons/metabolism ; Trinucleotide Repeat Expansion

المؤلفون: Machiela E; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, United States., Jeloka R; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, United States., Caron NS; Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada., Mehta S; The Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Schmidt ME; Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada., Baddeley HJE; Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada., Tom CM; The Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Polturi N; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, United States., Xie Y; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, United States., Mattis VB; The Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Hayden MR; Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada., Southwell AL; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, United States.; Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada.

المصدر: Frontiers in aging neuroscience [Front Aging Neurosci] 2020 Sep 18; Vol. 12, pp. 524369. Date of Electronic Publication: 2020 Sep 18 (Print Publication: 2020).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101525824 Publication Model: eCollection Cited Medium: Print ISSN: 1663-4365 (Print) Linking ISSN: 16634365 NLM ISO Abbreviation: Front Aging Neurosci Subsets: PubMed not MEDLINE

المؤلفون: Bartl S; AFFiRiS AG, Vienna, Austria. Electronic address: stefan.bartl@affiris.com., Oueslati A; Université Laval/Centre de recherche du CHU, Québec, Canada., Southwell AL; CMMT, University of British Columbia, Vancouver, Canada., Siddu A; Université Laval/Centre de recherche du CHU, Québec, Canada., Parth M; AFFiRiS AG, Vienna, Austria., David LS; Université Laval/Centre de recherche du CHU, Québec, Canada., Maxan A; Université Laval/Centre de recherche du CHU, Québec, Canada., Salhat N; AFFiRiS AG, Vienna, Austria., Burkert M; AFFiRiS AG, Vienna, Austria., Mairhofer A; AFFiRiS AG, Vienna, Austria., Friedrich T; AFFiRiS AG, Vienna, Austria., Pankevych H; AFFiRiS AG, Vienna, Austria., Balazs K; AFFiRiS AG, Vienna, Austria., Staffler G; AFFiRiS AG, Vienna, Austria., Hayden MR; CMMT, University of British Columbia, Vancouver, Canada., Cicchetti F; Université Laval/Centre de recherche du CHU, Québec, Canada., Smrzka OW; AFFiRiS AG, Vienna, Austria; Ablevia biotech GmbH, Vienna, Austria.

المصدر: Neurobiology of disease [Neurobiol Dis] 2020 Jul; Vol. 141, pp. 104943. Date of Electronic Publication: 2020 May 12.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Monoclonal/*administration & dosage , Huntingtin Protein/*genetics , Huntingtin Protein/*metabolism , Huntington Disease/*immunology , Huntington Disease/*metabolism, Animals ; Biological Transport ; Female ; HEK293 Cells ; HeLa Cells ; Humans ; Huntington Disease/prevention & control ; Mice, Inbred BALB C ; Mutation ; Protein Aggregation, Pathological/immunology ; Protein Aggregation, Pathological/metabolism ; Protein Aggregation, Pathological/prevention & control

المؤلفون: Caron NS; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.; BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada., Southwell AL; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.; BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA., Brouwers CC; Department of Research & Development, uniQure biopharma B.V., Amsterdam, the Netherlands., Cengio LD; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada., Xie Y; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada.; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA., Black HF; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.; BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada., Anderson LM; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada., Ko S; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada., Zhu X; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA., van Deventer SJ; Department of Research & Development, uniQure biopharma B.V., Amsterdam, the Netherlands., Evers MM; Department of Research & Development, uniQure biopharma B.V., Amsterdam, the Netherlands., Konstantinova P; Department of Research & Development, uniQure biopharma B.V., Amsterdam, the Netherlands., Hayden MR; Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.; BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.

المصدر: Nucleic acids research [Nucleic Acids Res] 2020 Jan 10; Vol. 48 (1), pp. 36-54.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: Huntingtin Protein/*genetics , Huntington Disease/*therapy , MicroRNAs/*genetics , Molecular Targeted Therapy/*methods , Parvovirinae/*genetics , RNA, Messenger/*genetics, Animals ; Animals, Genetically Modified ; Astrocytes/metabolism ; Astrocytes/pathology ; Base Sequence ; Corpus Striatum/metabolism ; Corpus Striatum/pathology ; Dependovirus ; Disease Models, Animal ; Gene Dosage ; Genetic Vectors/chemistry ; Genetic Vectors/metabolism ; Humans ; Huntingtin Protein/antagonists & inhibitors ; Huntingtin Protein/metabolism ; Huntington Disease/genetics ; Huntington Disease/metabolism ; Huntington Disease/pathology ; Mice ; MicroRNAs/administration & dosage ; MicroRNAs/metabolism ; Neuroglia/metabolism ; Neuroglia/pathology ; Neurons/metabolism ; Neurons/pathology ; Parvovirinae/metabolism ; Psychomotor Performance ; RNA Stability ; RNA, Messenger/antagonists & inhibitors ; RNA, Messenger/metabolism ; Trinucleotide Repeats

SCR Organism: Adeno-associated virus-5