المؤلفون: Lee JH; Medical Scientist Training Program, Roy J and Lucille A Carver College of Medicine, Iowa City, IA 52242, USA., Tecedor L; The Center for Cell and Molecular Therapy, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Chen YH; The Center for Cell and Molecular Therapy, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Monteys AM; The Center for Cell and Molecular Therapy, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Sowada MJ; The Center for Cell and Molecular Therapy, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Thompson LM; Departments of Psychiatry and Human Behavior, and Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA., Davidson BL; The Center for Cell and Molecular Therapy, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; The Department of Pathology & Laboratory Medicine, The Children's Hospital of Philadelphia and The University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: davidsonbl@email.chop.edu.

المصدر: Neuron [Neuron] 2015 Jan 21; Vol. 85 (2), pp. 303-15. Date of Electronic Publication: 2014 Dec 31.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE

مواضيع طبية MeSH: GTP-Binding Proteins/*metabolism , Huntington Disease/*metabolism , Monomeric GTP-Binding Proteins/*metabolism , Multiprotein Complexes/*metabolism , Neostriatum/*metabolism , Neuropeptides/*metabolism , Serotonin Plasma Membrane Transport Proteins/*metabolism , Signal Transduction/*physiology , TOR Serine-Threonine Kinases/*metabolism, Animals ; Atrophy ; Disease Models, Animal ; GTP-Binding Proteins/genetics ; Humans ; Huntington Disease/genetics ; Lipogenesis/genetics ; Mechanistic Target of Rapamycin Complex 1 ; Mice ; Multiprotein Complexes/genetics ; Neostriatum/pathology ; Phenotype ; Ras Homolog Enriched in Brain Protein ; Serotonin Plasma Membrane Transport Proteins/genetics ; TOR Serine-Threonine Kinases/genetics

المؤلفون: Monteys AM; The Center for Cell and Molecular Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Spengler RM; Internal Medicine, University of Iowa, Iowa City, IA 52242, USA., Dufour BD; Division of Neuroscience, Oregon National Primate Research Center, Beaverton, OR 97006, USA Department of Behavioral Neuroscience, Oregon Health Sciences University, Portland, OR 97239, USA., Wilson MS; Internal Medicine, University of Iowa, Iowa City, IA 52242, USA., Oakley CK; Internal Medicine, University of Iowa, Iowa City, IA 52242, USA., Sowada MJ; The Center for Cell and Molecular Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., McBride JL; Division of Neuroscience, Oregon National Primate Research Center, Beaverton, OR 97006, USA Department of Behavioral Neuroscience, Oregon Health Sciences University, Portland, OR 97239, USA., Davidson BL; The Center for Cell and Molecular Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA davidsonbl@email.chop.edu.

المصدر: Nucleic acids research [Nucleic Acids Res] 2014 Dec 01; Vol. 42 (21), pp. 13315-27. Date of Electronic Publication: 2014 Oct 20.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: RNA Interference*, Brain/*drug effects , MicroRNAs/*toxicity , Nerve Tissue Proteins/*genetics, Animals ; Base Sequence ; Brain/metabolism ; Brain Diseases/chemically induced ; Cell Line ; HEK293 Cells ; Humans ; Huntingtin Protein ; Macaca mulatta ; Mice ; MicroRNAs/chemistry ; MicroRNAs/metabolism ; Nerve Tissue Proteins/metabolism ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Nucleotides ; RNA, Messenger/metabolism

المؤلفون: Lee JH; Medical Scientist Training Program, Roy J and Lucille A Carver College of Medicine, Iowa City, IA, USA Department of Molecular Physiology & Biophysics, Roy J and Lucille A Carver College of Medicine, Iowa City, IA, USA., Sowada MJ; Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, Iowa City, IA, USA., Boudreau RL; Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, Iowa City, IA, USA., Aerts AM; Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, Iowa City, IA, USA., Thedens DR; Department of Radiology, Roy J and Lucille A Carver College of Medicine, Iowa City, IA, USA., Nopoulos P; Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, Iowa City, IA, USA., Davidson BL; Department of Molecular Physiology & Biophysics, Roy J and Lucille A Carver College of Medicine, Iowa City, IA, USA Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, Iowa City, IA, USA Department of Neurology, Roy J and Lucille A Carver College of Medicine, Iowa City, IA, USA.

المصدر: Journal of Huntington's disease [J Huntingtons Dis] 2014; Vol. 3 (1), pp. 65-71.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: IOS Press Country of Publication: Netherlands NLM ID: 101589965 Publication Model: Print Cited Medium: Print ISSN: 1879-6397 (Print) Linking ISSN: 18796397 NLM ISO Abbreviation: J Huntingtons Dis Subsets: MEDLINE

مواضيع طبية MeSH: MicroRNAs*, GTP-Binding Proteins/*antagonists & inhibitors , Huntington Disease/*metabolism , Mutant Proteins/*metabolism , Neostriatum/*pathology , Nerve Tissue Proteins/*metabolism , Nuclear Proteins/*metabolism, Animals ; Anxiety/metabolism ; Atrophy ; Behavior, Animal ; Disease Models, Animal ; Genetic Therapy ; Huntingtin Protein ; Huntington Disease/genetics ; Magnetic Resonance Imaging ; Phenotype