المؤلفون: Speca, DJ, Ogata, G, Mandikian, D, Bishop, HI, Wiler, SW, Eum, K, Wenzel, H Jürgen, Doisy, ET, Matt, L, Campi, KL, Golub, MS, Nerbonne, JM, Hell, JW, Trainor, BC, Sack, JT, Schwartzkroin, PA, Trimmer, JS

المصدر: Genes, brain, and behavior. 13(4)

مصطلحات موضوعية: Hippocampus, Neurons, Animals, Mice, Inbred C57BL, Mice, Seizures, Flurothyl, Pilocarpine, Convulsants, Maze Learning, Gene Deletion, Action Potentials, Long-Term Potentiation, Phenotype, Shab Potassium Channels, Hyperactivity, Kcnb1, Kcnb1tm1Dgen, long-term potentiation, seizure, Kcnb1(tm1Dgen), Inbred C57BL, Neurology & Neurosurgery, Biological Sciences, Medical and Health Sciences, Psychology and Cognitive Sciences

URL الوصول: https://escholarship.org/uc/item/7j75t5d2

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المؤلفون: Speca DJ; Department of Pharmacology, UC Davis School of Medicine., Diaz E; Department of Pharmacology, UC Davis School of Medicine; ediaz@ucdavis.edu.

المصدر: Journal of visualized experiments : JoVE [J Vis Exp] 2020 Mar 29 (157). Date of Electronic Publication: 2020 Mar 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Video-Audio Media

بيانات الدورية: Publisher: MYJoVE Corporation Country of Publication: United States NLM ID: 101313252 Publication Model: Electronic Cited Medium: Internet ISSN: 1940-087X (Electronic) Linking ISSN: 1940087X NLM ISO Abbreviation: J Vis Exp Subsets: MEDLINE

مواضيع طبية MeSH: Brain/*metabolism , Electrophoretic Mobility Shift Assay/*methods , Membrane Proteins/*metabolism, Animals ; Lipoylation/physiology ; Mice

المؤلفون: Matt L; Department of Pharmacology, UC Davis School of Medicine, Davis, CA 95616, USA., Kirk LM; Department of Pharmacology, UC Davis School of Medicine, Davis, CA 95616, USA., Chenaux G; Department of Pharmacology, UC Davis School of Medicine, Davis, CA 95616, USA., Speca DJ; Department of Pharmacology, UC Davis School of Medicine, Davis, CA 95616, USA., Puhger KR; MIND Institute, Department of Psychiatry and Behavioral Sciences, UC Davis School of Medicine, Sacramento, CA 95817, USA., Pride MC; MIND Institute, Department of Psychiatry and Behavioral Sciences, UC Davis School of Medicine, Sacramento, CA 95817, USA., Qneibi M; Department of Biochemistry and Molecular Biology, Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel., Haham T; Department of Biochemistry and Molecular Biology, Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel., Plambeck KE; Department of Pharmacology, UC Davis School of Medicine, Davis, CA 95616, USA., Stern-Bach Y; Department of Biochemistry and Molecular Biology, Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel., Silverman JL; MIND Institute, Department of Psychiatry and Behavioral Sciences, UC Davis School of Medicine, Sacramento, CA 95817, USA., Crawley JN; MIND Institute, Department of Psychiatry and Behavioral Sciences, UC Davis School of Medicine, Sacramento, CA 95817, USA., Hell JW; Department of Pharmacology, UC Davis School of Medicine, Davis, CA 95616, USA. Electronic address: jwhell@ucdavis.edu., Díaz E; Department of Pharmacology, UC Davis School of Medicine, Davis, CA 95616, USA. Electronic address: ediaz@ucdavis.edu.

المصدر: Cell reports [Cell Rep] 2018 Feb 27; Vol. 22 (9), pp. 2246-2253.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Cognition* , Excitatory Postsynaptic Potentials* , Neuronal Plasticity*, Membrane Proteins/*metabolism , Nerve Tissue Proteins/*metabolism , Receptors, AMPA/*metabolism , Synapses/*metabolism, Animals ; Female ; Genes, Reporter ; Hippocampus/metabolism ; Kinetics ; Long-Term Potentiation ; Memory ; Mice, Inbred C57BL ; Mice, Knockout ; Mutation/genetics ; Protein Subunits/metabolism ; Task Performance and Analysis ; Xenopus laevis

المؤلفون: Speca DJ; Department of Pharmacology, University of California, Davis, CA, 95616, USA. djspeca@ucdavis.edu., Trimmer JS; Department of Neurobiology, Physiology and Behavior, University of California, Davis, CA, 95616, USA.; Department of Physiology and Membrane Biology, University of California, Davis, CA, 95616, USA., Peterson AS; Department of Molecular Biology, Genentech, South San Francisco, CA, 94080, USA., Díaz E; Department of Pharmacology, University of California, Davis, CA, 95616, USA.

المصدر: Mammalian genome : official journal of the International Mammalian Genome Society [Mamm Genome] 2017 Dec; Vol. 28 (11-12), pp. 465-475. Date of Electronic Publication: 2017 Sep 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer-Verlag Country of Publication: United States NLM ID: 9100916 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1777 (Electronic) Linking ISSN: 09388990 NLM ISO Abbreviation: Mamm Genome Subsets: MEDLINE

مواضيع طبية MeSH: Membrane Proteins/*genetics , Mutagenesis/*genetics , Mutation, Missense/*genetics , Nerve Tissue Proteins/*genetics , Protein Domains/*genetics, Animals ; Cell Line ; Chromosomes, Mammalian/genetics ; Exome/genetics ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Phenotype ; Exome Sequencing/methods

المؤلفون: Chenaux G; Department of Pharmacology, University of California, Davis, California 95616; Center for Neuroscience, University of California, Davis, California 95616., Matt L; Department of Pharmacology, University of California , Davis, California 95616., Hill TC; Center for Neuroscience, University of California , Davis, California 95616., Kaur I; Department of Pharmacology, University of California , Davis, California 95616., Liu XB; Center for Neuroscience, University of California , Davis, California 95616., Kirk LM; Department of Pharmacology, University of California , Davis, California 95616., Speca DJ; Department of Pharmacology, University of California , Davis, California 95616., McMahon SA; Department of Pharmacology, University of California , Davis, California 95616., Zito K; Center for Neuroscience, University of California , Davis, California 95616., Hell JW; Department of Pharmacology, University of California , Davis, California 95616., Díaz E; Department of Pharmacology, University of California , Davis, California 95616.

المصدر: ENeuro [eNeuro] 2016 Oct 21; Vol. 3 (5). Date of Electronic Publication: 2016 Oct 21 (Print Publication: 2016).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 101647362 Publication Model: eCollection Cited Medium: Internet ISSN: 2373-2822 (Electronic) Linking ISSN: 23732822 NLM ISO Abbreviation: eNeuro Subsets: MEDLINE

مواضيع طبية MeSH: CA1 Region, Hippocampal/*growth & development , CA1 Region, Hippocampal/*metabolism , Carrier Proteins/*genetics , Synapses/*metabolism, Animals ; CA1 Region, Hippocampal/ultrastructure ; Cells, Cultured ; Disks Large Homolog 4 Protein ; Female ; Glutamic Acid/metabolism ; Guanylate Kinases/metabolism ; Male ; Membrane Proteins/metabolism ; Mice, Inbred C57BL ; Mice, Transgenic ; Neuronal Plasticity/physiology ; Receptors, AMPA/metabolism ; Receptors, N-Methyl-D-Aspartate/metabolism ; Synapses/ultrastructure ; Tissue Culture Techniques

المؤلفون: Thiffault I; Center for Pediatric Genomic Medicine, Department of Pathology and Laboratory Medicine, and Department of Pediatrics, Children's Mercy Hospital, Kansas City, MO 64108., Speca DJ; Department of Neurobiology, Physiology and Behavior, Department of Physiology and Membrane Biology, and Department of Anesthesiology and Pain Medicine, University of California, Davis, Davis, CA 95616., Austin DC; Department of Neurobiology, Physiology and Behavior, Department of Physiology and Membrane Biology, and Department of Anesthesiology and Pain Medicine, University of California, Davis, Davis, CA 95616., Cobb MM; Department of Neurobiology, Physiology and Behavior, Department of Physiology and Membrane Biology, and Department of Anesthesiology and Pain Medicine, University of California, Davis, Davis, CA 95616., Eum KS; Department of Neurobiology, Physiology and Behavior, Department of Physiology and Membrane Biology, and Department of Anesthesiology and Pain Medicine, University of California, Davis, Davis, CA 95616., Safina NP; Center for Pediatric Genomic Medicine, Department of Pathology and Laboratory Medicine, and Department of Pediatrics, Children's Mercy Hospital, Kansas City, MO 64108., Grote L; Center for Pediatric Genomic Medicine, Department of Pathology and Laboratory Medicine, and Department of Pediatrics, Children's Mercy Hospital, Kansas City, MO 64108., Farrow EG; Center for Pediatric Genomic Medicine, Department of Pathology and Laboratory Medicine, and Department of Pediatrics, Children's Mercy Hospital, Kansas City, MO 64108., Miller N; Center for Pediatric Genomic Medicine, Department of Pathology and Laboratory Medicine, and Department of Pediatrics, Children's Mercy Hospital, Kansas City, MO 64108., Soden S; Center for Pediatric Genomic Medicine, Department of Pathology and Laboratory Medicine, and Department of Pediatrics, Children's Mercy Hospital, Kansas City, MO 64108 Center for Pediatric Genomic Medicine, Department of Pathology and Laboratory Medicine, and Department of Pediatrics, Children's Mercy Hospital, Kansas City, MO 64108 University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108., Kingsmore SF; Center for Pediatric Genomic Medicine, Department of Pathology and Laboratory Medicine, and Department of Pediatrics, Children's Mercy Hospital, Kansas City, MO 64108 Center for Pediatric Genomic Medicine, Department of Pathology and Laboratory Medicine, and Department of Pediatrics, Children's Mercy Hospital, Kansas City, MO 64108 Center for Pediatric Genomic Medicine, Department of Pathology and Laboratory Medicine, and Department of Pediatrics, Children's Mercy Hospital, Kansas City, MO 64108 University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108., Trimmer JS; Department of Neurobiology, Physiology and Behavior, Department of Physiology and Membrane Biology, and Department of Anesthesiology and Pain Medicine, University of California, Davis, Davis, CA 95616 Department of Neurobiology, Physiology and Behavior, Department of Physiology and Membrane Biology, and Department of Anesthesiology and Pain Medicine, University of California, Davis, Davis, CA 95616 jsack@ucdavis.edu jtrimmer@ucdavis.edu csaunders@cmh.edu., Saunders CJ; Center for Pediatric Genomic Medicine, Department of Pathology and Laboratory Medicine, and Department of Pediatrics, Children's Mercy Hospital, Kansas City, MO 64108 Center for Pediatric Genomic Medicine, Department of Pathology and Laboratory Medicine, and Department of Pediatrics, Children's Mercy Hospital, Kansas City, MO 64108 University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108 jsack@ucdavis.edu jtrimmer@ucdavis.edu csaunders@cmh.edu., Sack JT; Department of Neurobiology, Physiology and Behavior, Department of Physiology and Membrane Biology, and Department of Anesthesiology and Pain Medicine, University of California, Davis, Davis, CA 95616 Department of Neurobiology, Physiology and Behavior, Department of Physiology and Membrane Biology, and Department of Anesthesiology and Pain Medicine, University of California, Davis, Davis, CA 95616 jsack@ucdavis.edu jtrimmer@ucdavis.edu csaunders@cmh.edu.

المصدر: The Journal of general physiology [J Gen Physiol] 2015 Nov; Vol. 146 (5), pp. 399-410.

نوع المنشور: Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985110R Publication Model: Print Cited Medium: Internet ISSN: 1540-7748 (Electronic) Linking ISSN: 00221295 NLM ISO Abbreviation: J Gen Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Mutation, Missense*, Epilepsy/*genetics , Shab Potassium Channels/*metabolism, Action Potentials ; Animals ; CHO Cells ; COS Cells ; Chlorocebus aethiops ; Cricetinae ; Cricetulus ; Epilepsy/diagnosis ; Female ; Humans ; Ion Channel Gating ; Potassium/metabolism ; Protein Transport ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Shab Potassium Channels/genetics

المؤلفون: Speca DJ; Department of Neurology and the Ernest Gallo Clinic and Research Center, University of California San Francisco, Emeryville, California, United States of America. dave.speca@gmail.com, Chihara D, Ashique AM, Bowers MS, Pierce-Shimomura JT, Lee J, Rabbee N, Speed TP, Gularte RJ, Chitwood J, Medrano JF, Liao M, Sonner JM, Eger EI 2nd, Peterson AS, McIntire SL

المصدر: PLoS genetics [PLoS Genet] 2010 Aug 12; Vol. 6 (8). Date of Electronic Publication: 2010 Aug 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: Electronic Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

مواضيع طبية MeSH: Body Weight* , Mutation*, Ethanol/*metabolism , Mice/*metabolism , Nerve Tissue Proteins/*genetics , Nerve Tissue Proteins/*metabolism, Animals ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/growth & development ; Caenorhabditis elegans/metabolism ; Caenorhabditis elegans/physiology ; Caenorhabditis elegans Proteins/genetics ; Caenorhabditis elegans Proteins/metabolism ; Female ; Ion Channels/genetics ; Ion Channels/metabolism ; Male ; Membrane Proteins ; Mice/genetics ; Mice/growth & development ; Mice/physiology ; Mice, Inbred C57BL ; Motor Activity