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1دورية أكاديمية
المؤلفون: Joseph A. Reddy, Melissa Nelson, Christina Dircksen, Marilynn Vetzel, Theresa Johnson, Vicky Cross, Elaine Westrick, LongWu Qi, Spencer Hahn, Hari Krishna Santhapuram, Garth Parham, Kevin Wang, Jeremy F. Vaughn, Albert Felten, Michael Pugh, June Lu, Patrick Klein, Iontcho R. Vlahov, Christopher P. Leamon
المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2045-2322
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المؤلفون: Iontcho Radoslavov Vlahov, Garth L. Parham, Patrick J. Klein, Elaine Westrick, June Lu, Christopher P. Leamon, Christina Dircksen, Marilynn Vetzel, Jeremy F. Vaughn, Albert Felten, Melissa Nelson, Vicky A. Cross, Longwu Qi, Kevin Wang, Hari Krishna Santhapuram, Joseph A. Reddy, Theresa Johnson, Spencer Hahn, Michael Pugh
المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reportsمصطلحات موضوعية: Drug Evaluation, Preclinical, Triple Negative Breast Neoplasms, Pharmacology, Ligands, KB Cells, Mice, chemistry.chemical_compound, Drug Delivery Systems, media_common, Ovarian Neoplasms, Vintafolide, Multidisciplinary, Drug discovery, Folate Receptors, GPI-Anchored, Cross-Linking Reagents, Oncology, Paclitaxel, Folate receptor, Medicine, Female, medicine.drug, Drug, Alkylating Agents, Science, media_common.quotation_subject, Mice, Nude, Antineoplastic Agents, Article, Inhibitory Concentration 50, Dogs, Folic Acid, medicine, Animals, Humans, Vinca Alkaloids, IC50, Cisplatin, DNA, DNA Crosslinking Agent, Xenograft Model Antitumor Assays, In vitro, Endometrial Neoplasms, Rats, Mice, Inbred C57BL, chemistry, Drug Design, Cattle
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المؤلفون: Jeff Nicoson, Kevin Wang, Fei You, Hanna F. Klein, Longwu Qi, Jeremy F. Vaughn, Iontcho Radoslavov Vlahov, Hari Krishna Santhapuram, Joe Reddy, Dan Reno, Garth L. Parham, Paul J. Kleindl, Spencer Hahn, Ning Zou, Christopher P. Leamon, Albert Felten
المصدر: Bioorganicmedicinal chemistry letters. 30(7)
مصطلحات موضوعية: Oxazolidine, Clinical Biochemistry, Imine, Pharmaceutical Science, Pyrrolobenzodiazepine, Mice, Nude, behavioral disciplines and activities, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Benzodiazepines, Neoplasms, Drug Discovery, Animals, Humans, Prodrugs, Pyrroles, Molecular Biology, chemistry.chemical_classification, Antibiotics, Antineoplastic, 010405 organic chemistry, Organic Chemistry, Folate Receptors, GPI-Anchored, Aromatic amine, Prodrug, Combinatorial chemistry, Xenograft Model Antitumor Assays, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Diazepine, chemistry, Folate receptor, Drug Design, Molecular Medicine, Female, Conjugate, HeLa Cells
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4
المؤلفون: Jeremy F. Vaughn, Joseph A. Reddy, Hari Krishna Santhapuram, Fei You, Hanna F. Klein, Melissa Nelson, Albert Felten, Longwu Qi, Paul J. Kleindl, Christopher P. Leamon, Iontcho Radoslavov Vlahov, Jeff Nicoson, Spencer Hahn, Marilynn Vetzel, Kevin Wang, Garth L. Parham
المصدر: Bioconjugate Chemistry. 28:2921-2931
مصطلحات موضوعية: 0301 basic medicine, Oxazolidine, Imine, Reactive intermediate, Biomedical Engineering, Pharmaceutical Science, Antineoplastic Agents, Bioengineering, Chemistry Techniques, Synthetic, 01 natural sciences, KB Cells, Benzodiazepines, 03 medical and health sciences, chemistry.chemical_compound, Neoplasms, Humans, Moiety, Prodrugs, Pyrroles, Molecular Targeted Therapy, Pharmacology, chemistry.chemical_classification, 010405 organic chemistry, Organic Chemistry, Aromatic amine, Prodrug, Combinatorial chemistry, 0104 chemical sciences, 030104 developmental biology, Diazepine, chemistry, Drug Design, Linker, Biotechnology
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المؤلفون: Alicia Bloomfield, Iontcho Radoslavov Vlahov, Melissa Nelson, Christopher P. Leamon, Marilynn Vetzel, Kevin Wang, Paul J. Kleindl, Ryan Dorton, Joseph A. Reddy, Spencer Hahn
المصدر: Bioconjugate chemistry. 30(6)
مصطلحات موضوعية: Glutamate Carboxypeptidase II, Male, Biomedical Engineering, Pharmaceutical Science, Mice, Nude, Bioengineering, Antineoplastic Agents, 02 engineering and technology, urologic and male genital diseases, 01 natural sciences, Prostate cancer, Antigen, Cell Line, Tumor, LNCaP, medicine, Glutamate carboxypeptidase II, Animals, Humans, Pharmacology, 010405 organic chemistry, Chemistry, Organic Chemistry, Cancer, Prostatic Neoplasms, 021001 nanoscience & nanotechnology, medicine.disease, Xenograft Model Antitumor Assays, In vitro, 0104 chemical sciences, Docetaxel, Cell culture, Pipecolic Acids, Antigens, Surface, Cancer research, 0210 nano-technology, Oligopeptides, Biotechnology, medicine.drug
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6
المؤلفون: Jeremy F. Vaughn, Iontcho Radoslavov Vlahov, Kevin Wang, Philip S. Low, Hari Krishna Santhapuram, Patrick J. Klein, Elaine Westrick, Fei You, Yingjuan Lu, Christopher P. Leamon, Mark A Gehrke, Torian W. Stinnette, Paul J. Kleindl, Kristin N. Wollak, Nikki Parker, Spencer Hahn, Vicky A. Cross
المصدر: Molecular Medicine. 21:584-596
مصطلحات موضوعية: Anti-Inflammatory Agents, Inflammation, Biology, Pharmacology, Aminopterin, Arthritis, Rheumatoid, Folic Acid, Pharmacokinetics, In vivo, Genetics, medicine, Animals, Humans, Everolimus, Folate Receptor 2, Molecular Biology, Genetics (clinical), PI3K/AKT/mTOR pathway, Cell Proliferation, Cell growth, TOR Serine-Threonine Kinases, Articles, Arthritis, Experimental, Rats, Folate receptor, Molecular Medicine, medicine.symptom, Signal Transduction, medicine.drug
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7
المؤلفون: Elaine Westrick, Iontcho Radoslavov Vlahov, Le-Cun Xu, Leroy W. Wheeler, Yingjuan Lu, Jeremy F. Vaughn, Christopher P. Leamon, Torian W. Stinnette, Kristin N. Wollak, Vicky A. Cross, Spencer Hahn
المصدر: Clinical Immunology. 150:64-77
مصطلحات موضوعية: Drug, Encephalomyelitis, Autoimmune, Experimental, media_common.quotation_subject, Immunology, Anti-Inflammatory Agents, Inflammation, medicine.disease_cause, Aminopterin, Autoimmunity, Uveitis, Peritoneal cavity, chemistry.chemical_compound, medicine, Animals, Immunology and Allergy, Folate Receptor 2, media_common, business.industry, Macrophages, Brain, Retinal, Ligand (biochemistry), Rats, medicine.anatomical_structure, Spinal Cord, chemistry, Rats, Inbred Lew, Folate receptor, Folic Acid Antagonists, Female, medicine.symptom, business, medicine.drug
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المؤلفون: Hari Krishna Santhapuram, Jeremy F. Vaughn, Kevin K.W. Wang, Iontcho Radoslavov Vlahov, Melissa Nelson, Christopher P. Leamon, Longwu Qi, Joseph A. Reddy, Spencer Hahn, Garth L. Parham, Marilynn Vetzel
المصدر: Cancer Research. 79:216-216
مصطلحات موضوعية: chemistry.chemical_classification, Cancer Research, Oxazolidine, Stereochemistry, Pyrrolobenzodiazepine, Aromatic amine, Ligand (biochemistry), Small molecule, chemistry.chemical_compound, Diazepine, Oncology, chemistry, Moiety, Linker
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::03b9f363487d6de9672d9e626bbb184b
https://doi.org/10.1158/1538-7445.am2019-216 -
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المؤلفون: Spencer Hahn, Paul J. Kleindl, Yu Wang, Iontcho Radoslavov Vlahov, Christopher P. Leamon, Marilynn Vetzel, Joseph A. Reddy
المصدر: Bioorganic & Medicinal Chemistry Letters. 21:6778-6781
مصطلحات موضوعية: Cell cycle checkpoint, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Chemistry Techniques, Synthetic, Biochemistry, Ion, Acetic acid, chemistry.chemical_compound, Nucleophile, Drug Discovery, Trifluoroacetic acid, Myxococcales, Cytotoxicity, Molecular Biology, Acetic Acid, Ions, Biological Products, Chemistry, Organic Chemistry, Bond formation, Tubulin Modulators, Pipecolic Acids, Molecular Medicine, Fermentation, Imines, Oligopeptides
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10
المؤلفون: Albert Felten, Hari Krishna Santhapuram, Spencer Hahn, Ning Zou, Christopher P. Leamon, Kevin K.W. Wang, Jeremy F. Vaughn, Paul J. Kleindl, Iontcho Radoslavov Vlahov
المصدر: Cancer Research. 78:757-757
مصطلحات موضوعية: chemistry.chemical_classification, Cancer Research, Imine, Aromatic amine, Prodrug, Oxime, Small molecule, Combinatorial chemistry, chemistry.chemical_compound, Oncology, chemistry, Aminal, Moiety, Linker
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5c95fff45c415f05978e90dd9639e797
https://doi.org/10.1158/1538-7445.am2018-757