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المؤلفون: Cui A, Patel R, Bosco P, Akcan U, Richters E, Delgado PB, Agalliu D, Sproul AA

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 08. Date of Electronic Publication: 2024 Aug 08.

نوع المنشور: Journal Article; Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Patel R, Cardona CL, Angeles E, Singh G, Ashok A, Teich AF, Sproul AA

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jun 28. Date of Electronic Publication: 2024 Jun 28.

نوع المنشور: Journal Article; Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Qu W; Department of Pathology and Cell Biology, Presbyterian Hospital, Columbia University, 650W 168th Street, New York, NY, USA., Lam M; Department of Neurology, Center for Translational and Computational Neuroimmunology, Neurological Institute, Columbia University, 710 West 168th Street, New York, NY, USA., McInvale JJ; Department of Pathology and Cell Biology, Presbyterian Hospital, Columbia University, 650W 168th Street, New York, NY, USA., Mares JA; Department of Neurology, Center for Translational and Computational Neuroimmunology, Neurological Institute, Columbia University, 710 West 168th Street, New York, NY, USA., Kwon S; Department of Pathology and Cell Biology, Presbyterian Hospital, Columbia University, 650W 168th Street, New York, NY, USA., Humala N; Department of Neurosurgery, Columbia University, New York, NY, USA., Mahajan A; Department of Neurosurgery, Columbia University, New York, NY, USA., Nguyen T; Department of Pathology and Cell Biology, Presbyterian Hospital, Columbia University, 650W 168th Street, New York, NY, USA., Jakubiak KA; Department of Pathology and Cell Biology, Presbyterian Hospital, Columbia University, 650W 168th Street, New York, NY, USA., Mun JY; Department of Pathology and Cell Biology, Presbyterian Hospital, Columbia University, 650W 168th Street, New York, NY, USA., Tedesco TG; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA., Al-Dalahmah O; Department of Pathology and Cell Biology, Presbyterian Hospital, Columbia University, 650W 168th Street, New York, NY, USA., Hussaini SA; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA., Sproul AA; Department of Pathology and Cell Biology, Presbyterian Hospital, Columbia University, 650W 168th Street, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA., Siegelin MD; Department of Pathology and Cell Biology, Presbyterian Hospital, Columbia University, 650W 168th Street, New York, NY, USA., De Jager PL; Department of Neurology, Center for Translational and Computational Neuroimmunology, Neurological Institute, Columbia University, 710 West 168th Street, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA., Canoll P; Department of Pathology and Cell Biology, Presbyterian Hospital, Columbia University, 650W 168th Street, New York, NY, USA., Menon V; Department of Neurology, Center for Translational and Computational Neuroimmunology, Neurological Institute, Columbia University, 710 West 168th Street, New York, NY, USA. vm2545@cumc.columbia.edu.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA. vm2545@cumc.columbia.edu., Hargus G; Department of Pathology and Cell Biology, Presbyterian Hospital, Columbia University, 650W 168th Street, New York, NY, USA. gh2374@cumc.columbia.edu.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA. gh2374@cumc.columbia.edu.

المصدر: Acta neuropathologica [Acta Neuropathol] 2024 Jun 25; Vol. 147 (1), pp. 107. Date of Electronic Publication: 2024 Jun 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE

مواضيع طبية MeSH: Induced Pluripotent Stem Cells* , Alzheimer Disease*/genetics , Alzheimer Disease*/pathology , Alzheimer Disease*/metabolism , Neurons*/metabolism , Neurons*/pathology , Transcriptome* , Amyloid beta-Protein Precursor*/genetics , Amyloid beta-Protein Precursor*/metabolism, Humans ; Animals ; Mice ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Mutation ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Synapses/pathology ; Synapses/metabolism ; Amyloid beta-Peptides/metabolism ; Signal Transduction/genetics ; Signal Transduction/physiology

المؤلفون: Al-Dalahmah O; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA; Taub Institute for Research on Alzheimer's Disease & the Aging Brain, Columbia University, New York, NY 10032, USA., Lam M; Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA., McInvale JJ; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA., Qu W; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA., Nguyen T; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA., Mun JY; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA., Kwon S; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA., Ifediora N; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA., Mahajan A; Department of Neurosurgery, Columbia University, New York, NY 10032, USA., Humala N; Department of Neurosurgery, Columbia University, New York, NY 10032, USA., Winters T; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA., Angeles E; Taub Institute for Research on Alzheimer's Disease & the Aging Brain, Columbia University, New York, NY 10032, USA., Jakubiak KA; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA., Kühn R; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA., Kim YA; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA., De Rosa MC; Division of Molecular Genetics, Department of Pediatrics, Columbia University, New York, NY 10032, USA., Doege CA; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA., Paryani F; Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA., Flowers X; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA., Dovas A; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA., Mela A; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA., Lu H; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA., DeTure MA; Department of Neuroscience, The Mayo Clinic Florida, Jacksonville, FL 32224, USA., Vonsattel JP; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA., Wszolek ZK; Department of Neurology, The Mayo Clinic Florida, Jacksonville, FL 32224, USA., Dickson DW; Department of Neuroscience, The Mayo Clinic Florida, Jacksonville, FL 32224, USA., Kuhlmann T; Institute of Neuropathology, University Hospital Münster, Münster 48149, Germany., Zaehres H; Institute of Anatomy, Ruhr University Bochum, Medical Faculty, Bochum 44801, Germany; Max Planck Institute for Molecular Biomedicine, Münster 48149, Germany., Schöler HR; Max Planck Institute for Molecular Biomedicine, Münster 48149, Germany., Sproul AA; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA; Taub Institute for Research on Alzheimer's Disease & the Aging Brain, Columbia University, New York, NY 10032, USA., Siegelin MD; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA., De Jager PL; Taub Institute for Research on Alzheimer's Disease & the Aging Brain, Columbia University, New York, NY 10032, USA; Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA., Goldman JE; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA; Taub Institute for Research on Alzheimer's Disease & the Aging Brain, Columbia University, New York, NY 10032, USA., Menon V; Taub Institute for Research on Alzheimer's Disease & the Aging Brain, Columbia University, New York, NY 10032, USA; Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA., Canoll P; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA., Hargus G; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA; Taub Institute for Research on Alzheimer's Disease & the Aging Brain, Columbia University, New York, NY 10032, USA. Electronic address: gh2374@cumc.columbia.edu.

المصدر: Cell stem cell [Cell Stem Cell] 2024 May 02; Vol. 31 (5), pp. 676-693.e10. Date of Electronic Publication: 2024 Apr 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101311472 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-9777 (Electronic) Linking ISSN: 18759777 NLM ISO Abbreviation: Cell Stem Cell Subsets: MEDLINE

مواضيع طبية MeSH: Osteopontin*/metabolism , Osteopontin*/genetics , Frontotemporal Dementia*/genetics , Frontotemporal Dementia*/pathology , Frontotemporal Dementia*/metabolism , Neurons*/metabolism , Neurons*/pathology , tau Proteins*/metabolism, Humans ; Animals ; Mice ; Neuroinflammatory Diseases/metabolism ; Neuroinflammatory Diseases/pathology ; Microglia/metabolism ; Microglia/pathology ; Mutation/genetics

المؤلفون: Haage V; Center for Translational & Computational Neuroimmunology, Neuroimmunology Division, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, United States., Tuddenham JF; Center for Translational & Computational Neuroimmunology, Neuroimmunology Division, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, United States.; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, United States., Comandante-Lou N; Center for Translational & Computational Neuroimmunology, Neuroimmunology Division, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, United States., Bautista A; Center for Translational & Computational Neuroimmunology, Neuroimmunology Division, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, United States., Monzel A; Department of Psychiatry, Division of Behavioral Medicine, College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, USA., Chiu R; Center for Translational & Computational Neuroimmunology, Neuroimmunology Division, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, United States., Fujita M; Center for Translational & Computational Neuroimmunology, Neuroimmunology Division, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, United States., Garcia FG; Center for Translational & Computational Neuroimmunology, Neuroimmunology Division, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, United States., Bhattarai P; Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, United States., Patel R; Department of Pathology and Cell Biology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, United States., Buonfiglioli A; Department of Psychiatry, Icahn School of Medicine, 1460 Madison Avenue, New York, NY, 10029, United States., Idiarte J; Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, United States., Herman M; Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, United States., Rinderspacher A; Department of Medicine, Columbia University, New York, NY 10032, United States., Mela A; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Zhao W; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, United States., Argenziano MG; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY 10032, USA., Furnari JL; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY 10032, USA., Banu MA; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY 10032, USA., Landry DW; Department of Medicine, Columbia University, New York, NY 10032, United States., Bruce JN; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY 10032, USA., Canoll P; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Zhang Y; Center for Translational & Computational Neuroimmunology, Neuroimmunology Division, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, United States., Nuriel T; Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, United States., Kizil C; Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, United States., Sproul AA; Department of Pathology and Cell Biology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, United States., de Witte LD; Department of Psychiatry, Icahn School of Medicine, 1460 Madison Avenue, New York, NY, 10029, United States., Sims PA; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, United States., Menon V; Center for Translational & Computational Neuroimmunology, Neuroimmunology Division, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, United States., Picard M; Department of Psychiatry, Division of Behavioral Medicine, College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, USA.; Department of Neurology, H. Houston Merritt Center, Columbia Translational Neuroscience Initiative, College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, USA.; New York State Psychiatric Institute, New York, USA.; Robert N Butler Columbia Aging Center, Columbia University Mailman School of Public Health, New York, NY, USA., De Jager PL; Center for Translational & Computational Neuroimmunology, Neuroimmunology Division, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, United States.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 Feb 06. Date of Electronic Publication: 2024 Feb 06.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Bartosch AMW; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York 10032.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York 10032., Youth EHH; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York 10032.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York 10032., Hansen S; Department of Neurology, Vanderbilt Memory & Alzheimer's Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee 37232., Wu Y; Department of Neurology, Vanderbilt Memory & Alzheimer's Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee 37232., Buchanan HM; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York 10032.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York 10032., Kaufman ME; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York 10032., Xiao H; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York 10032.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York 10032., Koo SY; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York 10032., Ashok A; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York 10032., Sivakumar S; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York 10032.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York 10032., Soni RK; Proteomics and Macromolecular Crystallography Shared Resource, Herbert Irving Comprehensive Cancer Center, New York, New York 10032., Dumitrescu LC; Department of Neurology, Vanderbilt Memory & Alzheimer's Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee 37232., Lam TG; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York 10032.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York 10032., Ropri AS; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York 10032.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York 10032., Lee AJ; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York 10032.; Department of Neurology, Center for Translational & Computational Neuroimmunology, Columbia University Irving Medical Center, New York Presbyterian Hospital, New York, New York 10032., Klein HU; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York 10032.; Department of Neurology, Center for Translational & Computational Neuroimmunology, Columbia University Irving Medical Center, New York Presbyterian Hospital, New York, New York 10032., Vardarajan BN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York 10032.; Department of Neurology, Columbia University Irving Medical Center, New York Presbyterian Hospital, New York, New York 10032., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612., Young-Pearse TL; Department of Neurology, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115.; Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts 02138., De Jager PL; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York 10032.; Department of Neurology, Center for Translational & Computational Neuroimmunology, Columbia University Irving Medical Center, New York Presbyterian Hospital, New York, New York 10032., Hohman TJ; Department of Neurology, Vanderbilt Memory & Alzheimer's Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee 37232., Sproul AA; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York 10032.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York 10032., Teich AF; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York 10032 aft25@cumc.columbia.edu.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York 10032.; Department of Neurology, Columbia University Irving Medical Center, New York Presbyterian Hospital, New York, New York 10032.

المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2024 Jan 17; Vol. 44 (3). Date of Electronic Publication: 2024 Jan 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/metabolism , Resilience, Psychological*, Female ; Humans ; Male ; Cognition ; Neurons/metabolism ; RNA ; RNA Splicing/genetics ; tau Proteins/metabolism

المؤلفون: Bartosch AMW; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032., Youth EHH; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032., Hansen S; Vanderbilt Memory & Alzheimer's Center, Department of Neurology, Vanderbilt University Medical Center, Nashville, TN 37232.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37232., Kaufman ME; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032., Xiao H; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032., Koo SY; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032., Ashok A; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032., Sivakumar S; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032., Soni RK; Proteomics and Macromolecular Crystallography Shared Resource, Herbert Irving Comprehensive Cancer Center, New York, NY 10032., Dumitrescu LC; Vanderbilt Memory & Alzheimer's Center, Department of Neurology, Vanderbilt University Medical Center, Nashville, TN 37232.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37232., Lam TG; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032., Ropri AS; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032., Lee AJ; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032.; Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Irving Medical Center, New York Presbyterian Hospital, New York, NY 10032., Klein HU; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032.; Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Irving Medical Center, New York Presbyterian Hospital, New York, NY 10032., Vardarajan BN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032.; Department of Neurology, Columbia University Irving Medical Center, New York Presbyterian Hospital, New York, NY 10032., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL 60612., Young-Pearse TL; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115; Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138., De Jager PL; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032.; Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Irving Medical Center, New York Presbyterian Hospital, New York, NY 10032., Hohman TJ; Vanderbilt Memory & Alzheimer's Center, Department of Neurology, Vanderbilt University Medical Center, Nashville, TN 37232.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37232., Sproul AA; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032., Teich AF; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032.; Department of Neurology, Columbia University Irving Medical Center, New York Presbyterian Hospital, New York, NY 10032.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Mar 21. Date of Electronic Publication: 2023 Mar 21.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Kim YA; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, USA.; Department of Pathology and Cell Biology, Columbia University, New York, USA., Siddiqui T; German Center for Neurodegenerative Diseases (DZNE), Helmholtz Association, Dresden, Germany., Blaze J; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, USA., Cosacak MI; German Center for Neurodegenerative Diseases (DZNE), Helmholtz Association, Dresden, Germany., Winters T; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, USA.; Department of Pathology and Cell Biology, Columbia University, New York, USA., Kumar A; Department of Pathology and Cell Biology, Columbia University, New York, USA., Tein E; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, USA., Sproul AA; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, USA.; Department of Pathology and Cell Biology, Columbia University, New York, USA., Teich AF; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, USA.; Department of Pathology and Cell Biology, Columbia University, New York, USA., Bartolini F; Department of Pathology and Cell Biology, Columbia University, New York, USA., Akbarian S; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, USA., Kizil C; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, USA.; German Center for Neurodegenerative Diseases (DZNE), Helmholtz Association, Dresden, Germany.; Department of Neurology, College of Physicians and Surgeons, Columbia University and the New York Presbyterian Hospital, New York, USA., Hargus G; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, USA. gh2374@cumc.columbia.edu.; Department of Pathology and Cell Biology, Columbia University, New York, USA. gh2374@cumc.columbia.edu., Santa-Maria I; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, USA. is2395@cumc.columbia.edu.; Department of Pathology and Cell Biology, Columbia University, New York, USA. is2395@cumc.columbia.edu.; Facultad de Ciencias Experimentales, Universidad Francisco de Vitoria, Edificio E, Pozuelo de Alarcón, Madrid, 28223, Spain. is2395@cumc.columbia.edu.

المصدر: Acta neuropathologica [Acta Neuropathol] 2023 Jan; Vol. 145 (1), pp. 29-48. Date of Electronic Publication: 2022 Nov 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE

مواضيع طبية MeSH: Induced Pluripotent Stem Cells*/metabolism , Alzheimer Disease*/genetics , Alzheimer Disease*/metabolism , MicroRNAs*/genetics, Mice ; Animals ; Humans ; Adult ; Methyltransferases/genetics ; Phosphorylation/genetics ; Drosophila melanogaster/genetics ; Drosophila melanogaster/metabolism ; tau Proteins/metabolism ; Mammals/metabolism