المؤلفون: McConville R; Division of Infectious Diseases & Immune Defence, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3010, Australia., Krol JMM; Division of Infectious Diseases & Immune Defence, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3010, Australia., Steel RWJ; Division of Infectious Diseases & Immune Defence, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3010, Australia., O'Neill MT; Division of Infectious Diseases & Immune Defence, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia., Davey BK; Division of Infectious Diseases & Immune Defence, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3010, Australia., Hodder AN; Division of Infectious Diseases & Immune Defence, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3010, Australia., Nebl T; Division of Infectious Diseases & Immune Defence, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3010, Australia., Cowman AF; Division of Infectious Diseases & Immune Defence, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3010, Australia., Kneteman N; Departments of Surgery, University of Alberta, Edmonton, AB T6G 2E1, Canada., Boddey JA; Division of Infectious Diseases & Immune Defence, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC 3010, Australia.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jul 09; Vol. 121 (28), pp. e2403442121. Date of Electronic Publication: 2024 Jul 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Plasmodium falciparum*/growth & development , Plasmodium falciparum*/genetics , Plasmodium falciparum*/metabolism , Protozoan Proteins*/metabolism , Protozoan Proteins*/genetics , Sporozoites*/metabolism , Sporozoites*/growth & development , Liver*/parasitology , Liver*/metabolism , Hepatocytes*/parasitology , Hepatocytes*/metabolism , Malaria, Falciparum*/parasitology, Animals ; Mice ; Humans

المؤلفون: Gualdrón-López M; ISGlobal, Barcelona Institute for Global Health, Barcelona, Spain; IGTP, Institute for Health Sciences Trias I Pujol, Barcelona, Spain., Díaz-Varela M; ISGlobal, Barcelona Institute for Global Health, Barcelona, Spain; IGTP, Institute for Health Sciences Trias I Pujol, Barcelona, Spain., Zanghi G; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA., Aparici-Herraiz I; ISGlobal, Barcelona Institute for Global Health, Barcelona, Spain; IGTP, Institute for Health Sciences Trias I Pujol, Barcelona, Spain., Steel RWJ; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA., Schäfer C; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA., Cuscó P; ISGlobal, Barcelona Institute for Global Health, Barcelona, Spain., Chuenchob V; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA., Kangwangransan N; Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok, Thailand., Billman ZP; Department of Laboratory Medicine and Pathology, and Department of Microbiology, University of Washington, Seattle, Washington, USA., Olsen TM; Department of Laboratory Medicine and Pathology, and Department of Microbiology, University of Washington, Seattle, Washington, USA., González JR; ISGlobal, Barcelona Institute for Global Health, Barcelona, Spain., Roobsoong W; MVRU, Mahidol Vivax Research Unit, Mahidol University, Bangkok, Thailand., Sattabongkot J; MVRU, Mahidol Vivax Research Unit, Mahidol University, Bangkok, Thailand., Murphy SC; Department of Laboratory Medicine and Pathology, and Department of Microbiology, University of Washington, Seattle, Washington, USA., Mikolajczak SA; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA., Borràs E; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain., Sabidó E; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain., Fernandez-Becerra C; ISGlobal, Barcelona Institute for Global Health, Barcelona, Spain; IGTP, Institute for Health Sciences Trias I Pujol, Barcelona, Spain., Flannery EL; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA., Kappe SHI; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA; Department of Pediatrics, University of Washington, Seattle, Washington, USA., Del Portillo HA; ISGlobal, Barcelona Institute for Global Health, Barcelona, Spain; IGTP, Institute for Health Sciences Trias I Pujol, Barcelona, Spain; ICREA, Catalan Institution for Research and Advanced Studies, Barcelona, Spain. Electronic address: hernandoa.delportillo@isglobal.org.

المصدر: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2022 Oct; Vol. 21 (10), pp. 100406. Date of Electronic Publication: 2022 Aug 24.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 101125647 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-9484 (Electronic) Linking ISSN: 15359476 NLM ISO Abbreviation: Mol Cell Proteomics Subsets: MEDLINE

مواضيع طبية MeSH: Malaria, Vivax*/drug therapy , Malaria, Vivax*/parasitology , Parasites* , Extracellular Vesicles*, Humans ; Mice ; Animals ; Plasmodium vivax ; Proteomics ; Proteome ; Filamins ; Liver ; Biomarkers ; Mass Spectrometry

المؤلفون: Lopaticki S; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia., McConville R; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., John A; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Geoghegan N; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Mohamed SD; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Verzier L; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Steel RWJ; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Evelyn C; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia., O'Neill MT; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia., Soler NM; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Scott NE; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia., Rogers KL; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Goddard-Borger ED; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia. goddard-borger.e@wehi.edu.au.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia. goddard-borger.e@wehi.edu.au., Boddey JA; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia. boddey@wehi.edu.au.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia. boddey@wehi.edu.au.

المصدر: Nature communications [Nat Commun] 2022 Aug 23; Vol. 13 (1), pp. 4944. Date of Electronic Publication: 2022 Aug 23.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Lopaticki S; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia., McConville R; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., John A; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Geoghegan N; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Mohamed SD; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Verzier L; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Steel RWJ; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Evelyn C; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia., O'Neill MT; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia., Soler NM; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Scott NE; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia., Rogers KL; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia., Goddard-Borger ED; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia. goddard-borger.e@wehi.edu.au.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia. goddard-borger.e@wehi.edu.au., Boddey JA; The Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville, VIC, 3052, Australia. boddey@wehi.edu.au.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia. boddey@wehi.edu.au.

المصدر: Nature communications [Nat Commun] 2022 Jul 29; Vol. 13 (1), pp. 4400. Date of Electronic Publication: 2022 Jul 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Culicidae*/metabolism , Malaria, Falciparum*/parasitology, Animals ; Glycosylation ; Humans ; Plasmodium falciparum/genetics ; Plasmodium falciparum/metabolism ; Protozoan Proteins/genetics ; Protozoan Proteins/metabolism ; Thrombospondins/metabolism ; Tryptophan/metabolism

المؤلفون: Ashton TD; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Ngo A; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Favuzza P; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Bullen HE; Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, 3004, Australia; Monash University, Clayton, Victoria 3800, Australia., Gancheva MR; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, Australia., Romeo O; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, Australia., Parkyn Schneider M; Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, 3004, Australia; Monash University, Clayton, Victoria 3800, Australia., Nguyen N; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Steel RWJ; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Duffy S; Discovery Biology, Griffith Institute for Drug Discovery, Griffith University, Nathan, Queensland 4111, Australia., Lowes KN; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Sabroux HJ; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Avery VM; Discovery Biology, Griffith Institute for Drug Discovery, Griffith University, Nathan, Queensland 4111, Australia., Boddey JA; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Wilson DW; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, Australia., Cowman AF; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Gilson PR; Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, 3004, Australia; Monash University, Clayton, Victoria 3800, Australia., Sleebs BE; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia. Electronic address: sleebs@wehi.edu.au.

المصدر: Bioorganic chemistry [Bioorg Chem] 2021 Dec; Vol. 117, pp. 105359. Date of Electronic Publication: 2021 Sep 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Aniline Compounds/*chemistry , Aniline Compounds/*pharmacology , Antimalarials/*chemistry , Antimalarials/*pharmacology , Malaria/*drug therapy , Plasmodium/*drug effects , Quinazolines/*chemistry , Quinazolines/*pharmacology, Amination ; Aniline Compounds/therapeutic use ; Animals ; Antimalarials/therapeutic use ; Female ; Humans ; Malaria/parasitology ; Mice ; Plasmodium/physiology ; Plasmodium falciparum/drug effects ; Plasmodium falciparum/physiology ; Quinazolines/therapeutic use

المؤلفون: Evert BJ; Centre for Cell Factories and Biopolymers, Griffith Institute for Drug Discovery, Griffith University, Brisbane, QLD, Australia., Chen S; Centre for Cell Factories and Biopolymers, Griffith Institute for Drug Discovery, Griffith University, Brisbane, QLD, Australia., McConville R; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Steel RWJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Healer J; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Boddey JA; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Huntimer L; Elanco, Indianapolis, IN, USA., Rehm BHA; Centre for Cell Factories and Biopolymers, Griffith Institute for Drug Discovery, Griffith University, Brisbane, QLD, Australia. b.rehm@griffith.edu.au.; Menzies Health Institute Queensland (MHIQ), Griffith University, Gold Coast, QLD, Australia. b.rehm@griffith.edu.au.

المصدر: NPJ vaccines [NPJ Vaccines] 2021 Nov 29; Vol. 6 (1), pp. 141. Date of Electronic Publication: 2021 Nov 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Nature in partnership with the Sealy Center for Vaccine Development Country of Publication: England NLM ID: 101699863 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-0105 (Electronic) Linking ISSN: 20590105 NLM ISO Abbreviation: NPJ Vaccines Subsets: PubMed not MEDLINE

المؤلفون: Steel RWJ; Seattle Children's Research Institute, Seattle, WA, USA.; Infectious Diseases and Immune Defence Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia., Vigdorovich V; Seattle Children's Research Institute, Seattle, WA, USA., Dambrauskas N; Seattle Children's Research Institute, Seattle, WA, USA., Wilder BK; Seattle Children's Research Institute, Seattle, WA, USA.; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, 97006, USA., Arredondo SA; Seattle Children's Research Institute, Seattle, WA, USA., Goswami D; Seattle Children's Research Institute, Seattle, WA, USA., Kumar S; Seattle Children's Research Institute, Seattle, WA, USA., Carbonetti S; Seattle Children's Research Institute, Seattle, WA, USA., Swearingen KE; Institute for Systems Biology, Seattle, WA, USA., Nguyen T; Seattle Children's Research Institute, Seattle, WA, USA., Betz W; Seattle Children's Research Institute, Seattle, WA, USA., Camargo N; Seattle Children's Research Institute, Seattle, WA, USA., Fisher BS; Seattle Children's Research Institute, Seattle, WA, USA., Soden J; Retrogenix Ltd, Chinley, High Peak, SK23 6FJ, UK., Thomas H; Retrogenix Ltd, Chinley, High Peak, SK23 6FJ, UK., Freeth J; Retrogenix Ltd, Chinley, High Peak, SK23 6FJ, UK., Moritz RL; Institute for Systems Biology, Seattle, WA, USA., Noah Sather D; Seattle Children's Research Institute, Seattle, WA, USA. noah.sather@seattlechildrens.org.; Department of Pediatrics, University of Washington, Seattle, WA, USA. noah.sather@seattlechildrens.org.; Department of Global Health, University of Washington, Seattle, WA, USA. noah.sather@seattlechildrens.org., Kappe SHI; Seattle Children's Research Institute, Seattle, WA, USA. stefan.kappe@seattlechildrens.org.; Department of Pediatrics, University of Washington, Seattle, WA, USA. stefan.kappe@seattlechildrens.org.; Department of Global Health, University of Washington, Seattle, WA, USA. stefan.kappe@seattlechildrens.org.

المصدر: Scientific reports [Sci Rep] 2021 May 31; Vol. 11 (1), pp. 11328. Date of Electronic Publication: 2021 May 31.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Host-Pathogen Interactions*, Plasmodium falciparum/*metabolism , Protozoan Proteins/*metabolism , Receptor, Platelet-Derived Growth Factor beta/*metabolism, HEK293 Cells ; Humans ; Plasmodium vivax/metabolism ; Plasmodium yoelii/metabolism ; Protozoan Proteins/isolation & purification

المؤلفون: Favuzza P; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia., de Lera Ruiz M; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA., Thompson JK; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia., Triglia T; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia., Ngo A; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia., Steel RWJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia., Vavrek M; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA., Christensen J; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia., Healer J; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia., Boyce C; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA., Guo Z; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA., Hu M; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA., Khan T; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA., Murgolo N; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA., Zhao L; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA., Penington JS; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia., Reaksudsan K; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia., Jarman K; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia., Dietrich MH; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia., Richardson L; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia., Guo KY; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia., Lopaticki S; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia., Tham WH; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia., Rottmann M; Swiss Tropical and Public Health Institute, Basel 4002, Switzerland., Papenfuss T; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia., Robbins JA; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA., Boddey JA; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia., Sleebs BE; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia., Sabroux HJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia., McCauley JA; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA., Olsen DB; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA. Electronic address: david_olsen@merck.com., Cowman AF; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia. Electronic address: cowman@wehi.edu.au.

المصدر: Cell host & microbe [Cell Host Microbe] 2020 Apr 08; Vol. 27 (4), pp. 642-658.e12. Date of Electronic Publication: 2020 Feb 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101302316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1934-6069 (Electronic) Linking ISSN: 19313128 NLM ISO Abbreviation: Cell Host Microbe Subsets: MEDLINE

مواضيع طبية MeSH: Antimalarials/*pharmacology , Aspartic Acid Endopeptidases/*drug effects , Malaria/*drug therapy, Animals ; Disease Transmission, Infectious/prevention & control ; Life Cycle Stages/drug effects ; Merozoites/drug effects ; Mice ; Mice, Transgenic ; Plasmodium berghei/drug effects ; Plasmodium falciparum/drug effects

المؤلفون: Ebert G; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Lopaticki S; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia., O'Neill MT; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia., Steel RWJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Doerflinger M; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Rajasekaran P; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Yang ASP; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Erickson S; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Ioannidis L; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Arandjelovic P; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Mackiewicz L; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia., Allison C; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Silke J; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia., Pellegrini M; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia. Electronic address: pellegrini@wehi.edu.au., Boddey JA; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia. Electronic address: boddey@wehi.edu.au.

المصدر: Cell reports [Cell Rep] 2020 Mar 31; Vol. 30 (13), pp. 4343-4354.e4.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis*/drug effects, Hepatocytes/*pathology , Liver/*parasitology , Liver/*pathology , Malaria/*parasitology , Malaria/*pathology, Administration, Oral ; Animals ; Biological Availability ; Caspase 3/metabolism ; Culicidae/parasitology ; Dipeptides/administration & dosage ; Dipeptides/pharmacology ; Hepatocytes/drug effects ; Immunity/drug effects ; Indoles/administration & dosage ; Indoles/pharmacology ; Inhibitor of Apoptosis Proteins/antagonists & inhibitors ; Inhibitor of Apoptosis Proteins/metabolism ; Life Cycle Stages/drug effects ; Malaria/immunology ; Plasmodium/drug effects ; Plasmodium/growth & development ; Plasmodium/metabolism ; Protozoan Proteins/metabolism ; Sporozoites/drug effects ; Sporozoites/physiology ; Thiazoles/pharmacology ; Tumor Necrosis Factor-alpha/metabolism

المؤلفون: Zenklusen I; Clinical Immunology Unit, Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Switzerland., Jongo S; Ifakara Health Institute, Clinical Trial Unit, Bagamoyo, Tanzania., Abdulla S; Ifakara Health Institute, Clinical Trial Unit, Bagamoyo, Tanzania., Ramadhani K; Ifakara Health Institute, Clinical Trial Unit, Bagamoyo, Tanzania., Lee Sim BK; Sanaria Inc., Rockville, Maryland., Cardamone H; Center for Infectious Disease Research, Seattle, Washington., Flannery EL; Center for Infectious Disease Research, Seattle, Washington., Nguyen T; Center for Infectious Disease Research, Seattle, Washington., Fishbaugher M; Center for Infectious Disease Research, Seattle, Washington., Steel RWJ; Center for Infectious Disease Research, Seattle, Washington., Betz W; Center for Infectious Disease Research, Seattle, Washington., Carmago N; Center for Infectious Disease Research, Seattle, Washington., Mikolajczak S; Center for Infectious Disease Research, Seattle, Washington., Kappe SHI; Center for Infectious Disease Research, Seattle, Washington.; Department of Global Health, University of Washington, Seattle., Hoffman SL; Sanaria Inc., Rockville, Maryland., Sack BK; Center for Infectious Disease Research, Seattle, Washington., Daubenberger C; Clinical Immunology Unit, Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Switzerland.

المصدر: The Journal of infectious diseases [J Infect Dis] 2018 Apr 23; Vol. 217 (10), pp. 1569-1578.

نوع المنشور: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Protozoan/*immunology , Immunoglobulin M/*immunology , Malaria/*immunology , Malaria Vaccines/*immunology , Malaria, Falciparum/*immunology, Adult ; Antibody Formation/immunology ; Double-Blind Method ; Humans ; Immunization/methods ; Male ; Plasmodium falciparum/immunology ; Sporozoites/immunology ; Vaccination/methods ; Vaccines, Attenuated/immunology ; Volunteers ; Young Adult