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المؤلفون: Birgitta Karlsson Svalstedt, Anders Thelin, Annika Wellner, Johanna Vinblad, Margareta Herslöf, David Gustafsson, Yantao Chen, Cristian Bodin, Ola Fjellström, Stefan Blaho, Jenny Sandmark, Carina Johansson, Birgitta Rosengren, Sofia Martinsson, Tomas Fex, Jonas Boström, Andreas Moberg, Tomas Akerud, Emma Evertsson, Bingze Xu, Ryan Hicks, Magnus Althage, Emelie Jarkvist, Wolfgang Knecht, Per-Olof Eriksson, Marianne Ridderström, Ann-Margret Östlund-Lindqvist, Anna Tigerström, Anders Dahlén, Anne Legnehed, Thomas Antonsson, Alan Sabirsh, Inge Kalies, Fredrik Kartberg
المصدر: J Biol Chem
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Apolipoprotein B, Plasmin, Lysine, Sequence Homology, Ligands, Biochemistry, Kringle domain, Small Molecule Libraries, 03 medical and health sciences, Kringles, Protein Domains, medicine, Humans, Amino Acid Sequence, Molecular Biology, Apolipoproteins A, Fibrin, 030102 biochemistry & molecular biology, biology, Ligand, Chemistry, Cell growth, Molecular Bases of Disease, Cell Biology, Small molecule, High-Throughput Screening Assays, 030104 developmental biology, biology.protein, lipids (amino acids, peptides, and proteins), Protein Binding, medicine.drug, Lipoprotein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb534512cdcc56630f05e52c97ed62a
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المؤلفون: Stefan Blaho, Mathias Liljeblad, Mikko Hölttä, Fredrik Höök, Stefan Geschwindner, Namik Akkilic
المصدر: ACS Sensors. 4:3166-3174
مصطلحات موضوعية: Receptor, ErbB-4, Neuregulin-1, Bioengineering, Biosensing Techniques, 02 engineering and technology, Computational biology, 01 natural sciences, Limit of Detection, medicine, Humans, Avidity, Surface plasmon resonance, Neuregulin 1, Instrumentation, Immunoassay, Fluid Flow and Transfer Processes, Detection limit, medicine.diagnostic_test, biology, Chemistry, Process Chemistry and Technology, 010401 analytical chemistry, Antibodies, Monoclonal, Surface Plasmon Resonance, 021001 nanoscience & nanotechnology, 0104 chemical sciences, HEK293 Cells, Liposomes, biology.protein, Nanoparticles, Biomarker (medicine), 0210 nano-technology, Antibodies, Immobilized, Biosensor, Biomarkers, Fluorescent tag
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المؤلفون: Gangadhara Gangadhara, Nils Pemberton, Kostas Karabelas, Rebecca Rae, Mickael Mogemark, Christian Tyrchan, Tineke Papavoine, Göran Dahl, Perry Matthew, Helena Lindmark, Stefan Blaho, Linda Öster, Jenny Gunnarsson, Thomas Bohnacker, Matthias P. Wymann, Jens Petersen, Roger L. Williams
المصدر: Nature chemical biology. 15(4)
مصطلحات موضوعية: Models, Molecular, Conformational change, Stereochemistry, Class I Phosphatidylinositol 3-Kinases, Protein Conformation, Phthalimides, Plasma protein binding, Crystallography, X-Ray, Substrate Specificity, 03 medical and health sciences, Phosphatidylinositol 3-Kinases, Protein structure, Transferase, Class Ib Phosphatidylinositol 3-Kinase, Humans, Protein Isoforms, Binding site, Site-directed mutagenesis, Protein kinase A, Molecular Biology, Protein Kinase Inhibitors, 030304 developmental biology, Phosphoinositide-3 Kinase Inhibitors, chemistry.chemical_classification, Adenosine Triphosphatases, 0303 health sciences, Binding Sites, 030302 biochemistry & molecular biology, Cell Biology, Enzyme, chemistry, Mutagenesis, Site-Directed, Protein Binding
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المؤلفون: Emre M. Isin, David Blomberg Saitton, Eric Wellner, Rutger H. A. Folmer, Pernilla Ståhlberg, Kay Brickmann, Volker Schnecke, Öjvind Davidsson, Christoffer Bengtsson, Lars-Olof Larsson, Stefan Hallén, Pernilla Sörme, Hong Wan, Kenth Hallberg, Linda Öster, Ragnar Hovland, Lars Löfgren, Alleyn T. Plowright, Bengt Kull, Tobias Noeske, Stefan Blaho, Petra Johannesson, Tomas Drmota, Kristina Nilsson, Johan Broddefalk, Nick Oakes
المصدر: Bioorganicmedicinal chemistry. 19(10)
مصطلحات موضوعية: Male, Models, Molecular, Tertiary amine, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, Small Molecule Libraries, chemistry.chemical_compound, Mice, Structure-Activity Relationship, In vivo, Drug Discovery, Animals, Humans, Obesity, Enzyme Inhibitors, Molecular Biology, ADME, chemistry.chemical_classification, biology, Organic Chemistry, Fatty Acids, Acetyl-CoA carboxylase, Acetyl-CoA Carboxylase 1, Rats, Rats, Zucker, Malonyl Coenzyme A, Mice, Inbred C57BL, Enzyme, Malonyl-CoA, chemistry, Diabetes Mellitus, Type 2, Liver, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Acetyl-CoA Carboxylase
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