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1دورية أكاديمية
المؤلفون: Falchetti M; Laboratório de Farmacologia e Bioquímica do Câncer (LabCancer), Departamento de Farmacologia, Centro de Ciências Biológicas (CCB), Universidade Federal de Santa Catarina (UFSC), Florianópolis, Santa Catarina, 88040-900, Brazil., Delgobo M; Laboratório de Farmacologia e Bioquímica do Câncer (LabCancer), Departamento de Farmacologia, Centro de Ciências Biológicas (CCB), Universidade Federal de Santa Catarina (UFSC), Florianópolis, Santa Catarina, 88040-900, Brazil., Zancanaro H; Laboratório de Farmacologia e Bioquímica do Câncer (LabCancer), Departamento de Farmacologia, Centro de Ciências Biológicas (CCB), Universidade Federal de Santa Catarina (UFSC), Florianópolis, Santa Catarina, 88040-900, Brazil., Almeida K; Laboratório de Farmacologia e Bioquímica do Câncer (LabCancer), Departamento de Farmacologia, Centro de Ciências Biológicas (CCB), Universidade Federal de Santa Catarina (UFSC), Florianópolis, Santa Catarina, 88040-900, Brazil., das Neves RN; Laboratório de Farmacologia e Bioquímica do Câncer (LabCancer), Departamento de Farmacologia, Centro de Ciências Biológicas (CCB), Universidade Federal de Santa Catarina (UFSC), Florianópolis, Santa Catarina, 88040-900, Brazil; Greehey Children's Cancer Research Institute, University of Texas Health at San Antonio, San Antonio, TX, 78229, USA., Dos Santos B; Laboratório de Farmacologia e Bioquímica do Câncer (LabCancer), Departamento de Farmacologia, Centro de Ciências Biológicas (CCB), Universidade Federal de Santa Catarina (UFSC), Florianópolis, Santa Catarina, 88040-900, Brazil., Stefanes NM; Laboratório de Oncologia Experimental e Hemopatias (LOEH), Departamento de Análises Clínicas, Centro de Ciências da Saúde, Universidade Federal de Santa Catarina (UFSC), Florianópolis, Santa Catarina, 88040-900, Brazil., Bishop A; Greehey Children's Cancer Research Institute, University of Texas Health at San Antonio, San Antonio, TX, 78229, USA; Department of Cell Systems and Anatomy, University of Texas Health at San Antonio, San Antonio, TX, 78229, USA., Santos-Silva MC; Laboratório de Oncologia Experimental e Hemopatias (LOEH), Departamento de Análises Clínicas, Centro de Ciências da Saúde, Universidade Federal de Santa Catarina (UFSC), Florianópolis, Santa Catarina, 88040-900, Brazil., Zanotto-Filho A; Laboratório de Farmacologia e Bioquímica do Câncer (LabCancer), Departamento de Farmacologia, Centro de Ciências Biológicas (CCB), Universidade Federal de Santa Catarina (UFSC), Florianópolis, Santa Catarina, 88040-900, Brazil. Electronic address: https://labcancer.paginas.ufsc.br.
المصدر: Computers in biology and medicine [Comput Biol Med] 2023 Jan; Vol. 152, pp. 106347. Date of Electronic Publication: 2022 Nov 25.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1250250 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0534 (Electronic) Linking ISSN: 00104825 NLM ISO Abbreviation: Comput Biol Med Subsets: MEDLINE
مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung* , Lung Neoplasms*/drug therapy , Lung Neoplasms*/genetics , Lung Neoplasms*/pathology, Humans ; Auranofin/pharmacology ; Auranofin/therapeutic use ; Drug Repositioning ; Kelch-Like ECH-Associated Protein 1/genetics ; Kelch-Like ECH-Associated Protein 1/metabolism ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; NF-E2-Related Factor 2/therapeutic use ; Glutathione/metabolism ; Glutathione/therapeutic use
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2دورية أكاديمية
المؤلفون: Jacques AV; Laboratory of Experimental Oncology and Hemopathies, Department of Clinical Analysis, Florianópolis, Santa Catarina 88040-900, Brazil; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina 88040-900, Brazil., Stefanes NM; Laboratory of Experimental Oncology and Hemopathies, Department of Clinical Analysis, Florianópolis, Santa Catarina 88040-900, Brazil; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina 88040-900, Brazil., Walter LO; Laboratory of Experimental Oncology and Hemopathies, Department of Clinical Analysis, Florianópolis, Santa Catarina 88040-900, Brazil; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina 88040-900, Brazil., Perondi DM; Laboratory of Experimental Oncology and Hemopathies, Department of Clinical Analysis, Florianópolis, Santa Catarina 88040-900, Brazil; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina 88040-900, Brazil., Efe FDL; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina 88040-900, Brazil., de Souza LFS; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina 88040-900, Brazil; Structure and Activity Laboratory, Department of Chemistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina 88040-900, Brazil., Sens L; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina 88040-900, Brazil; Structure and Activity Laboratory, Department of Chemistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina 88040-900, Brazil., Syracuse SM; Laboratory of Experimental Oncology and Hemopathies, Department of Clinical Analysis, Florianópolis, Santa Catarina 88040-900, Brazil; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina 88040-900, Brazil., de Moraes ACR; Laboratory of Experimental Oncology and Hemopathies, Department of Clinical Analysis, Florianópolis, Santa Catarina 88040-900, Brazil; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina 88040-900, Brazil., de Oliveira AS; Department of Exact Sciences and Education, Federal University of Santa Catarina, Florianópolis, Santa Catarina 89036-002, Brazil; Laboratory of Medicinal and Computational Chemistry, Institute of Physics of São Carlos, University of São Paulo, São Carlos, São Paulo 13566-590, Brazil., Martins CT; Laboratory of Medicinal and Computational Chemistry, Institute of Physics of São Carlos, University of São Paulo, São Carlos, São Paulo 13566-590, Brazil., Magalhaes LG; Laboratory of Medicinal and Computational Chemistry, Institute of Physics of São Carlos, University of São Paulo, São Carlos, São Paulo 13566-590, Brazil., Andricopulo AD; Laboratory of Medicinal and Computational Chemistry, Institute of Physics of São Carlos, University of São Paulo, São Carlos, São Paulo 13566-590, Brazil., Silva LO; Laboratory of Experimental Oncology and Hemopathies, Department of Clinical Analysis, Florianópolis, Santa Catarina 88040-900, Brazil; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina 88040-900, Brazil., Nunes RJ; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina 88040-900, Brazil; Structure and Activity Laboratory, Department of Chemistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina 88040-900, Brazil., Santos-Silva MC; Laboratory of Experimental Oncology and Hemopathies, Department of Clinical Analysis, Florianópolis, Santa Catarina 88040-900, Brazil; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina 88040-900, Brazil. Electronic address: maria.claudia.silva@ufsc.br.
المصدر: Bioorganic chemistry [Bioorg Chem] 2021 Nov; Vol. 116, pp. 105315. Date of Electronic Publication: 2021 Sep 01.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
مواضيع طبية MeSH: Acetophenones/*pharmacology , Antineoplastic Agents/*pharmacology , Apoptosis/*drug effects , Chalcones/*pharmacology, Acetophenones/chemistry ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Chalcones/chemical synthesis ; Chalcones/chemistry ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Structure-Activity Relationship
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3دورية أكاديمية
المؤلفون: Bigolin A; Laboratory of Experimental Oncology and Hemopathies, Department of Clinical Analysis, Federal University of Santa Catarina., Maioral MF; Laboratory of Experimental Oncology and Hemopathies, Department of Clinical Analysis, Federal University of Santa Catarina., Stefanes NM; Laboratory of Experimental Oncology and Hemopathies, Department of Clinical Analysis, Federal University of Santa Catarina., Zatelli GA; Laboratory of Natural Products, Department of Pharmaceutical Sciences, Federal University of Santa Catarina, Florianópolis, SC, Brazil., Philippus AC; Laboratory of Natural Products, Department of Pharmaceutical Sciences, Federal University of Santa Catarina, Florianópolis, SC, Brazil., Falkenberg MB; Laboratory of Natural Products, Department of Pharmaceutical Sciences, Federal University of Santa Catarina, Florianópolis, SC, Brazil., Santos-Silva MC; Laboratory of Experimental Oncology and Hemopathies, Department of Clinical Analysis, Federal University of Santa Catarina.
المصدر: Anti-cancer drugs [Anticancer Drugs] 2020 Aug; Vol. 31 (7), pp. 709-717.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 9100823 Publication Model: Print Cited Medium: Internet ISSN: 1473-5741 (Electronic) Linking ISSN: 09594973 NLM ISO Abbreviation: Anticancer Drugs Subsets: MEDLINE
مواضيع طبية MeSH: Antineoplastic Agents, Phytogenic/*pharmacology , Benzoquinones/*pharmacology , Hematologic Neoplasms/*drug therapy, Antineoplastic Agents, Phytogenic/adverse effects ; Antineoplastic Agents, Phytogenic/isolation & purification ; Apoptosis/drug effects ; Apoptosis Inducing Factor/metabolism ; Benzoquinones/adverse effects ; Benzoquinones/isolation & purification ; Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Eugenia/chemistry ; Hematologic Neoplasms/metabolism ; Hematologic Neoplasms/pathology ; Humans ; Jurkat Cells ; K562 Cells ; Plant Extracts/isolation & purification ; Plant Extracts/pharmacology ; Proto-Oncogene Proteins c-bcl-2/metabolism ; bcl-2-Associated X Protein/metabolism
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4دورية أكاديمية
المؤلفون: Maioral MF; Experimental Oncology & Hemopathies Laboratory, Department of Clinical Analysis, Federal University of Santa Catarina, Florianópolis, Santa Catarina, 88040-900, Brazil.; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina, 88040-900, Brazil., Stefanes NM; Experimental Oncology & Hemopathies Laboratory, Department of Clinical Analysis, Federal University of Santa Catarina, Florianópolis, Santa Catarina, 88040-900, Brazil.; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina, 88040-900, Brazil., Neuenfeldt PD; Structure & Activity Laboratory, Department of Chemistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, 88040-900, Brazil., Chiaradia-Delatorre LD; Structure & Activity Laboratory, Department of Chemistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, 88040-900, Brazil., Nunes RJ; Structure & Activity Laboratory, Department of Chemistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, 88040-900, Brazil., Santos-Silva MC; Experimental Oncology & Hemopathies Laboratory, Department of Clinical Analysis, Federal University of Santa Catarina, Florianópolis, Santa Catarina, 88040-900, Brazil.; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina, 88040-900, Brazil.
المصدر: Future medicinal chemistry [Future Med Chem] 2020 Apr; Vol. 12 (8), pp. 673-688. Date of Electronic Publication: 2020 Mar 19.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Future Science Country of Publication: England NLM ID: 101511162 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1756-8927 (Electronic) Linking ISSN: 17568919 NLM ISO Abbreviation: Future Med Chem Subsets: MEDLINE
مواضيع طبية MeSH: Aldehydes/*pharmacology , Antineoplastic Agents/*pharmacology , Biphenyl Compounds/*pharmacology , Chalcones/*pharmacology, Aldehydes/chemistry ; Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Biphenyl Compounds/chemistry ; Cell Death/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Chalcones/chemical synthesis ; Chalcones/chemistry ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Endoplasmic Reticulum Stress/drug effects ; Humans ; Mice ; Structure-Activity Relationship
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5دورية أكاديمية
المؤلفون: Maioral MF; Experimental Oncology and Hemopathies Laboratory, Clinical Analysis Department, Federal University of Santa Catarina, Florianópolis, SC, CEP: 88040-900, Brazil.; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, SC, CEP: 88040-900, Brazil., Stefanes NM; Experimental Oncology and Hemopathies Laboratory, Clinical Analysis Department, Federal University of Santa Catarina, Florianópolis, SC, CEP: 88040-900, Brazil.; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, SC, CEP: 88040-900, Brazil., Bigolin Á; Experimental Oncology and Hemopathies Laboratory, Clinical Analysis Department, Federal University of Santa Catarina, Florianópolis, SC, CEP: 88040-900, Brazil.; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, SC, CEP: 88040-900, Brazil., Zatelli GA; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, SC, CEP: 88040-900, Brazil., Philippus AC; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, SC, CEP: 88040-900, Brazil., de Barcellos Falkenberg M; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, SC, CEP: 88040-900, Brazil., Santos-Silva MC; Experimental Oncology and Hemopathies Laboratory, Clinical Analysis Department, Federal University of Santa Catarina, Florianópolis, SC, CEP: 88040-900, Brazil. maria.claudia.silva@ufsc.br.; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, Florianópolis, SC, CEP: 88040-900, Brazil. maria.claudia.silva@ufsc.br.; Laboratório de Oncologia Experimental e Hemopatias (LOEH), Departamento de Análises Clínicas, Centro de Ciências da Saúde - Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil. maria.claudia.silva@ufsc.br.
المصدر: Investigational new drugs [Invest New Drugs] 2019 Oct; Vol. 37 (5), pp. 912-922. Date of Electronic Publication: 2018 Dec 19.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 8309330 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-0646 (Electronic) Linking ISSN: 01676997 NLM ISO Abbreviation: Invest New Drugs Subsets: MEDLINE
مواضيع طبية MeSH: Apoptosis/*drug effects , Cell Cycle Checkpoints/*drug effects , Hydroquinones/*pharmacology , Leukemia, Myeloid, Acute/*pathology , Precursor Cell Lymphoblastic Leukemia-Lymphoma/*pathology, Antineoplastic Agents/pharmacology ; Humans ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/metabolism ; Mitochondria/drug effects ; Mitochondria/metabolism ; Mitochondria/pathology ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/metabolism ; Reactive Oxygen Species/metabolism ; Signal Transduction ; Tumor Cells, Cultured
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6دورية أكاديمية
المؤلفون: Perondi DM; Experimental Oncology and Hemopathies Laboratory, Department of Clinical Analysis.; Post-Graduation Program in Pharmacy, Health Science Center., Jacques AV; Experimental Oncology and Hemopathies Laboratory, Department of Clinical Analysis.; Post-Graduation Program in Pharmacy, Health Science Center., Stefanes NM; Experimental Oncology and Hemopathies Laboratory, Department of Clinical Analysis.; Post-Graduation Program in Pharmacy, Health Science Center., Maioral MF; Experimental Oncology and Hemopathies Laboratory, Department of Clinical Analysis.; Post-Graduation Program in Pharmacy, Health Science Center., Sens L; Structure and Activity Laboratory, Department of Chemistry Department.; Post- Graduation Program in Chemistry, Physical and Mathematical Center, Federal University of Santa Catarina, Florianópolis., Pacheco LA; Structure and Activity Laboratory, Department of Chemistry Department.; Post- Graduation Program in Chemistry, Physical and Mathematical Center, Federal University of Santa Catarina, Florianópolis., Cury NM; Molecular Biology Laboratory, Centro Infantil Boldrini., Nunes RJ; Structure and Activity Laboratory, Department of Chemistry Department.; Post- Graduation Program in Chemistry, Physical and Mathematical Center, Federal University of Santa Catarina, Florianópolis., Yunes JA; Molecular Biology Laboratory, Centro Infantil Boldrini.; Department of Medical Genetics, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil., Santos-Silva MC; Experimental Oncology and Hemopathies Laboratory, Department of Clinical Analysis.; Post-Graduation Program in Pharmacy, Health Science Center.
المصدر: Anti-cancer drugs [Anticancer Drugs] 2019 Sep; Vol. 30 (8), pp. 828-837.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 9100823 Publication Model: Print Cited Medium: Internet ISSN: 1473-5741 (Electronic) Linking ISSN: 09594973 NLM ISO Abbreviation: Anticancer Drugs Subsets: MEDLINE
مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Gene Expression Regulation, Neoplastic/*drug effects , Leukemia, Myeloid, Acute/*drug therapy , Leukocytes, Mononuclear/*drug effects , Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy , Thiosemicarbazones/*chemistry, Antineoplastic Agents/chemistry ; Apoptosis ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Cell Cycle ; Cell Proliferation ; Humans ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/metabolism ; Leukemia, Myeloid, Acute/pathology ; Membrane Potential, Mitochondrial ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/metabolism ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Tumor Cells, Cultured
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7دورية أكاديمية
المؤلفون: Stefanes NM; Experimental Oncology and Hemopathies Laboratory, Clinical Analysis Department, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil., Toigo J; Structure and Activity Laboratory, Chemistry Department, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil., Maioral MF; Experimental Oncology and Hemopathies Laboratory, Clinical Analysis Department, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil., Jacques AV; Experimental Oncology and Hemopathies Laboratory, Clinical Analysis Department, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil., Chiaradia-Delatorre LD; Structure and Activity Laboratory, Chemistry Department, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil., Perondi DM; Experimental Oncology and Hemopathies Laboratory, Clinical Analysis Department, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil., Ribeiro AAB; Experimental Oncology and Hemopathies Laboratory, Clinical Analysis Department, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil., Bigolin Á; Experimental Oncology and Hemopathies Laboratory, Clinical Analysis Department, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil., Pirath IMS; Experimental Oncology and Hemopathies Laboratory, Clinical Analysis Department, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil., Duarte BF; Experimental Oncology and Hemopathies Laboratory, Clinical Analysis Department, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil., Nunes RJ; Structure and Activity Laboratory, Chemistry Department, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil. Electronic address: nunesrjj@ufsc.br., Santos-Silva MC; Experimental Oncology and Hemopathies Laboratory, Clinical Analysis Department, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil; Post-Graduation Program in Pharmacy, Health Science Center, Federal University of Santa Catarina, CEP: 88040-900, Florianópolis, SC, Brazil. Electronic address: maria.claudia.silva@ufsc.br.
المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2019 Jan 15; Vol. 27 (2), pp. 375-382. Date of Electronic Publication: 2018 Dec 07.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE
مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Apoptosis/*drug effects , Pyrazoles/*pharmacology, Acute Disease ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Apoptosis Inducing Factor/metabolism ; Caspase 3/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Humans ; Leukemia/drug therapy ; Membrane Potential, Mitochondrial/drug effects ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Pyrazoles/chemical synthesis ; Pyrazoles/chemistry ; S Phase Cell Cycle Checkpoints/drug effects ; Survivin/metabolism ; bcl-2-Associated X Protein/metabolism
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8دورية أكاديمية
المؤلفون: Maioral MF; Laboratório de Oncologia Experimental e Hemopatias, Departamento de Análises Clínicas, Universidade Federal de Santa Catarina, Campus Trindade, CEP: 88040-900, Florianópolis, SC, Brazil; Programa de Pós-Graduação em Farmácia, Centro de Ciências da Saúde, Universidade Federal de Santa Catarina, 88040-900 Florianópolis, SC, Brazil., Bodack CDN; Laboratório de Oncologia Experimental e Hemopatias, Departamento de Análises Clínicas, Universidade Federal de Santa Catarina, Campus Trindade, CEP: 88040-900, Florianópolis, SC, Brazil., Stefanes NM; Laboratório de Oncologia Experimental e Hemopatias, Departamento de Análises Clínicas, Universidade Federal de Santa Catarina, Campus Trindade, CEP: 88040-900, Florianópolis, SC, Brazil; Programa de Pós-Graduação em Farmácia, Centro de Ciências da Saúde, Universidade Federal de Santa Catarina, 88040-900 Florianópolis, SC, Brazil., Bigolin Á; Laboratório de Oncologia Experimental e Hemopatias, Departamento de Análises Clínicas, Universidade Federal de Santa Catarina, Campus Trindade, CEP: 88040-900, Florianópolis, SC, Brazil; Programa de Pós-Graduação em Farmácia, Centro de Ciências da Saúde, Universidade Federal de Santa Catarina, 88040-900 Florianópolis, SC, Brazil., Mascarello A; Laboratório Estrutura e Atividade, Departamento de Química, Universidade Federal de Santa Catarina, Campus Trindade, CEP: 88040-900, Florianópolis, SC, Brazil., Chiaradia-Delatorre LD; Laboratório Estrutura e Atividade, Departamento de Química, Universidade Federal de Santa Catarina, Campus Trindade, CEP: 88040-900, Florianópolis, SC, Brazil., Yunes RA; Laboratório Estrutura e Atividade, Departamento de Química, Universidade Federal de Santa Catarina, Campus Trindade, CEP: 88040-900, Florianópolis, SC, Brazil., Nunes RJ; Laboratório Estrutura e Atividade, Departamento de Química, Universidade Federal de Santa Catarina, Campus Trindade, CEP: 88040-900, Florianópolis, SC, Brazil., Santos-Silva MC; Laboratório de Oncologia Experimental e Hemopatias, Departamento de Análises Clínicas, Universidade Federal de Santa Catarina, Campus Trindade, CEP: 88040-900, Florianópolis, SC, Brazil; Programa de Pós-Graduação em Farmácia, Centro de Ciências da Saúde, Universidade Federal de Santa Catarina, 88040-900 Florianópolis, SC, Brazil. Electronic address: maria.claudia.silva@ufsc.br.
المصدر: Biochimie [Biochimie] 2017 Sep; Vol. 140, pp. 48-57. Date of Electronic Publication: 2017 Jun 10.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 1264604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1638-6183 (Electronic) Linking ISSN: 03009084 NLM ISO Abbreviation: Biochimie Subsets: MEDLINE
مواضيع طبية MeSH: Chalcones*/chemical synthesis , Chalcones*/chemistry , Chalcones*/pharmacology , Cytotoxins*/chemical synthesis , Cytotoxins*/chemistry , Cytotoxins*/pharmacology, Apoptosis/*drug effects , Gene Expression Regulation, Neoplastic/*drug effects , Hematologic Neoplasms/*drug therapy , Neoplasm Proteins/*biosynthesis, A549 Cells ; Animals ; Drug Screening Assays, Antitumor ; Female ; HL-60 Cells ; HeLa Cells ; Hematologic Neoplasms/genetics ; Hematologic Neoplasms/metabolism ; Hematologic Neoplasms/pathology ; Humans ; Jurkat Cells ; Male ; Mice ; NIH 3T3 Cells ; Neoplasm Proteins/genetics ; U937 Cells