المؤلفون: Stephane Bourgeois, Daniel F. Carr, Crispin O. Musumba, Alexander Penrose, Celestine Esume, Andrew P. Morris, Andrea L. Jorgensen, J. Eunice Zhang, D. Mark Pritchard, Panos Deloukas, Munir Pirmohamed

المصدر: EBioMedicine, Vol 74, Iss , Pp 103728- (2021)

مصطلحات موضوعية: NSAID, ulcer, Aspirin, GWAS, Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396421005223; https://doaj.org/toc/2352-3964

URL الوصول: https://doaj.org/article/e356fc46996447cfa33cfd26c73f0564

المؤلفون: Stavroula Kanoni, Satish Kumar, Charalampia Amerikanou, Mary Jo Kurth, Maria G. Stathopoulou, Stephane Bourgeois, Christine Masson, Aimo Kannt, Lucia Cesarini, Maria-Spyridoula Kontoe, Maja Milanović, Francisco J. Roig, Mirjana Beribaka, Jonica Campolo, Nuria Jiménez-Hernández, Nataša Milošević, Carlos Llorens, Ilias Smyrnioudis, M. Pilar Francino, Nataša Milić, Andriana C. Kaliora, Maria Giovanna Trivella, Mark W. Ruddock, Milica Medić-Stojanoska, Amalia Gastaldelli, John Lamont, Panos Deloukas, George V. Dedoussis, Sophie Visvikis-Siest

المصدر: Frontiers in Immunology, Vol 12 (2021)

مصطلحات موضوعية: non-alcoholic fatty liver disease, inflammation, oxidative stress, Mastiha, nutrigenetics, randomized clinical trial, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.683028/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/01cf24ceb3e947749ca21d7d2aed1f4f

المؤلفون: Assaf Gottlieb, Roxana Daneshjou, Marianne DeGorter, Stephane Bourgeois, Peter J. Svensson, Mia Wadelius, Panos Deloukas, Stephen B. Montgomery, Russ B. Altman

المصدر: Genome Medicine, Vol 9, Iss 1, Pp 1-9 (2017)

مصطلحات موضوعية: Pharmacogenomics, Warfarin dose, International Warfarin Pharmacogenetics Consortium, African Americans, Medicine, Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13073-017-0495-0; https://doaj.org/toc/1756-994X

URL الوصول: https://doaj.org/article/261a8c9e0ef54d29a241ab8e535b6302

المؤلفون: J. E. Zhang, Kathrin Klein, Andrea L. Jorgensen, Ben Francis, Ana Alfirevic, Stephane Bourgeois, Panagiotis Deloukas, Ulrich M. Zanger, Munir Pirmohamed

المصدر: Frontiers in Pharmacology, Vol 8 (2017)

مصطلحات موضوعية: warfarin, pharmacogenetics, mRNA expression, CYP4F2, CYP4F11, CYP4F12, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fphar.2017.00323/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/2294ece5faa04b3b93fdecbb1ec11339

المؤلفون: Fumihiko Takeuchi, Ralph McGinnis, Stephane Bourgeois, Chris Barnes, Niclas Eriksson, Nicole Soranzo, Pamela Whittaker, Venkatesh Ranganath, Vasudev Kumanduri, William McLaren, Lennart Holm, Jonatan Lindh, Anders Rane, Mia Wadelius, Panos Deloukas

المصدر: PLoS Genetics, Vol 5, Iss 3, p e1000433 (2009)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC2652833?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

URL الوصول: https://doaj.org/article/df3a790e40f54e6e8cbc621c4c11b5f6

المؤلفون: Johann S, Hawe, Rory, Wilson, Katharina T, Schmid, Li, Zhou, Lakshmi Narayanan, Lakshmanan, Benjamin C, Lehne, Brigitte, Kühnel, William R, Scott, Matthias, Wielscher, Yik Weng, Yew, Clemens, Baumbach, Dominic P, Lee, Eirini, Marouli, Manon, Bernard, Liliane, Pfeiffer, Pamela R, Matías-García, Matias I, Autio, Stephane, Bourgeois, Christian, Herder, Ville, Karhunen, Thomas, Meitinger, Holger, Prokisch, Wolfgang, Rathmann, Michael, Roden, Sylvain, Sebert, Jean, Shin, Konstantin, Strauch, Weihua, Zhang, Wilson L W, Tan, Stefanie M, Hauck, Juliane, Merl-Pham, Harald, Grallert, Eudes G V, Barbosa, Thomas, Illig, Annette, Peters, Tomas, Paus, Zdenka, Pausova, Panos, Deloukas, Roger S Y, Foo, Marjo-Riitta, Jarvelin, Jaspal S, Kooner, Marie, Loh, Matthias, Heinig, Christian, Gieger, Melanie, Waldenberger, Krina T, Zondervan

المصدر: Nat. Genet. 54, 18–29 (2022)

مصطلحات موضوعية: DNA Replication, Asia, Quantitative Trait Loci, Genetic Variation, Blood Pressure, CD8-Positive T-Lymphocytes, DNA Methylation, Polymorphism, Single Nucleotide, Body Mass Index, Arthritis, Rheumatoid, Europe, Leukocytes, Genetics, Humans, CpG Islands, Genome-Wide Association Study

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f854cdd047ff8e3bf4d76fef7f78d2a7
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=64018

المؤلفون: Rajagopal Krishnamoorthy, Yusuke Nakamura, Alice Giontella, Elisa Danese, Munir Pirmohamed, Hoi Y. Tong, Angela Tagetti, Marie-Anne Loriot, Pietro Minuz, Anke H. Maitland-van der Zee, Sheng-Lan Tan, Jim K Burmester, Richard B. Kim, Jamila Alessandra Perini, Ming Ta Michael Lee, Nita A. Limdi, Min Huang, Mohamed H. Shahin, Guilherme Suarez-Kurtz, Vanessa Roldán, Carlos Isaza, Hersh Sagreiya, Hye Sun Gwak, Vijay Kumar Kutala, Han-Jing Cen, Russ B. Altman, Antonio J. Carcas, Kunihiko Itoh, Vaiva Lesauskaite, Richard L. Berg, Cristina Mazzaccara, Kyung Eun Lee, Mariana R. Botton, Jieying Eunice Zhang, Anthonius de Boer, Yumao Zhang, Inna Y. Gong, Marianne K. Kringen, Paola Borgiani, Taimour Y. Langaee, Monica Taljaard, Vacis Tatarunas, Panos Deloukas, Chrisly Dillon, Alberto M. Borobia, Michael D. Caldwell, Katarzyna Drozda, Larisa H. Cavallari, Julie A. Johnson, Stephane Bourgeois, Lucia Sacchetti, Saurabh Singh Rathore, Stuart A. Scott, Martina Montagnana, Li-Zi Zhao, Charles A. Rivers, Mahmut Ozer, Taisei Mushiroda, Cristina Lucía Dávila-Fajardo, Andras Paldi, Marisa Cañadas-Garre, Rocío González-Conejero, Talitha I. Verhoef, Sherief Khalifa, Ivet Suriapranata, Carlo Federico Zambon, Balraj Mittal, Sara Raimondi, Ece Genc, Virginie Siguret, Andrea H. Ramirez, Cinzia Ciccacci, Keita Hirai, Enrique Jiménez-Varo, Hong-Hao Zhou, Anil Pathare, Steven A. Lubitz, Josh C. Denny, Aditi Shendre, Leonardo Beltrán, Kari Bente Foss Haug, Cristiano Fava, Vittorio Pengo

المساهمون: Department of Biochemistry, Università degli Studi di Pavia = University of Pavia (UNIPV), Department of Morphological and Biomedical Sciences, Università degli studi di Verona = University of Verona (UNIVR), Laboratoire de Mécanique et d'Acoustique [Marseille] (LMA ), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS), Queen Mary University of London (QMUL), Merck and Co., Merck & Co. Inc, Innovations thérapeutiques en hémostase = Innovative Therapies in Haemostasis (IThEM - U1140), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Service d’Hématologie Biologique [CHU Lariboisière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Paediatric Pulmonology, Pulmonology, APH - Personalized Medicine, Danese, Elisa, Raimondi, Sara, Montagnana, Martina, Tagetti, Angela, Langaee, Taimour, Borgiani, Paola, Ciccacci, Cinzia, Carcas, Antonio J, Borobia, Alberto M, Tong, Hoi Y, Dávila-Fajardo, Cristina, Rodrigues Botton, Mariana, Bourgeois, Stephane, Deloukas, Pano, Caldwell, Michael D, Burmester, Jim K, Berg, Richard L, Cavallari, Larisa H, Drozda, Katarzyna, Huang, Min, Zhao, Li-Zi, Cen, Han-Jing, Gonzalez-Conejero, Rocio, Roldan, Vanessa, Nakamura, Yusuke, Mushiroda, Taisei, Gong, Inna Y, Kim, Richard B, Hirai, Keita, Itoh, Kunihiko, Isaza, Carlo, Beltrán, Leonardo, Jiménez-Varo, Enrique, Cañadas-Garre, Marisa, Giontella, Alice, Kringen, Marianne K, Haug, Kari Bente Fo, Gwak, Hye Sun, Lee, Kyung Eun, Minuz, Pietro, Lee, Ming Ta Michael, Lubitz, Steven A, Scott, Stuart, Mazzaccara, Cristina, Sacchetti, Lucia, Genç, Ece, Özer, Mahmut, Pathare, Anil, Krishnamoorthy, Rajagopal, Paldi, Andra, Siguret, Virginie, Loriot, Marie-Anne, Kutala, Vijay Kumar, Suarez-Kurtz, Guilherme, Perini, Jamila, Denny, Josh C, Ramirez, Andrea H, Mittal, Balraj, Rathore, Saurabh Singh, Sagreiya, Hersh, Altman, Ru, Shahin, Mohamed Hossam A, Khalifa, Sherief I, Limdi, Nita A, Rivers, Charle, Shendre, Aditi, Dillon, Chrisly, Suriapranata, Ivet M, Zhou, Hong-Hao, Tan, Sheng-Lan, Tatarunas, Vaci, Lesauskaite, Vaiva, Zhang, Yumao, Maitland-van der Zee, Anke H, Verhoef, Talitha I, de Boer, Anthoniu, Taljaard, Monica, Zambon, Carlo Federico, Pengo, Vittorio, Zhang, Jieying Eunice, Pirmohamed, Munir, Johnson, Julie A, Fava, Cristiano

المصدر: Clin Pharmacol Ther
Clinical Pharmacology and Therapeutics, 105(6), 1477. Nature Publishing Group
Danese, E, Sara, R, Montagnana, M, Tagetti, A, Langaee, T, Borgiani, P, Ciccacci, C, Carcas, A J, Borobia, A M, Tong, H Y, Davila Fajardo, C, Rodrigues Botton, M, Bourgeois, S, Deloukas, P, Caldwell, M D, Burmester, J K, Berg, R L, Cavallari, L H, Drozda, K, Huang, M, Zhao, L-Z, Cen, H-J, Gonzalez-Conejero, R, Roldan, V, Nakamura, Y, Mushiroda, T, Gong, I Y, Kim, R B, Hirai, K, Itoh, K, Isaza, C, Beltran, L, Jimenez-Varo, E, Cañadas-Garre, M, Giontella, A, Kristiansen Kringen, M, Bente Foss Haug, K, Gwak, H S, Lee, K E, Minuz, P, Lee, M T M, Lubitz, S A, Scott, S, Mazzaccara, C, Sacchetti, L, Genç, E, Özer, M, Pathare, A, Krishnamoorthy, R, Paldi, A, Siguret, V, Loriot, M-A, Kumar Kutala, V, Suarez-Kurtz, G, Perini, J, Denny, J C, Ramirez, A H, Mittal, B, Singh Rathore, S, Sagreiya, H, Altman, R, Shahin, M H A, Khalifa, S I, Lindi, N A, Rivers, C, Shendre, A, Dillon, C, Suriapranata, I M, Zhou, H-H, Tan, S-L, Tatarunas, V, Lesauskaite, V, Zhang, Y, Maitland-van der Zee, A H, Verhoef, T I, de Boer, A, Taljaard, M, Zambon, C F, Pengo, V, zhang, J E, Pirmohamed, M, Johnson, J A & Fava, C 2018, ' The effect of CYP4F2, VKORC1 and CYP2C9 in influencing coumarin dose. A single patient data meta-analysis in more than 15,000 individuals ', Clinical Pharmacology and Therapeutics . https://doi.org/10.1002/cpt.1323
Clinical Pharmacology and Therapeutics
Clinical Pharmacology and Therapeutics, 2019, 105 (6), pp.1477-1491. ⟨10.1002/cpt.1323⟩
Clinical pharmacology and therapeutics, 105(6), 1477-1491. Wiley-Blackwell
Clinical pharmacology and therapeutics
Paediatrics Publications

مصطلحات موضوعية: CYP2C9, CYP4F2, VKORC1, coumarin drugs, meta-analysis, pharmacogenetics, predictive models, Male, medicine.medical_specialty, [SDV]Life Sciences [q-bio], 030226 pharmacology & pharmacy, Polymorphism, Single Nucleotide, Article, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Coumarins, Internal medicine, Vitamin K Epoxide Reductases, Taverne, medicine, Humans, Pharmacology (medical), heterocyclic compounds, Dosing, Cytochrome P450 Family 4, Aged, Cytochrome P-450 CYP2C9, Pharmacology, Aged, 80 and over, Acenocoumarol, Dose-Response Relationship, Drug, business.industry, Middle Aged, Confidence interval, Settore MED/03 - Genetica Medica, 030220 oncology & carcinogenesis, Meta-analysis, Female, business, Pharmacogenetics, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f48f76671021f7043e3ac2ca8c9e251
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85061927761&origin=inward

المؤلفون: George Dedoussis, E. A. Katsareli, Andreas Alexandrou, John Griniatsos, Stephane Bourgeois, Jiannis Ragoussis, Alexandros C. Dimopoulos, Emmanouil T. Dermitzakis, Antigone S. Dimas, C. Amerikanou, Theodoros Diamantis, K. Rouskas

المصدر: Obesity surgery. 30(4)

مصطلحات موضوعية: Sleeve gastrectomy, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Population, Gastric Bypass, Bariatric Surgery, 030209 endocrinology & metabolism, Single-nucleotide polymorphism, 03 medical and health sciences, 0302 clinical medicine, Weight loss, Gastrectomy, Risk Factors, Linear regression, Weight Loss, medicine, Humans, Prospective Studies, Genetic risk, education, Prospective cohort study, Retrospective Studies, education.field_of_study, Nutrition and Dietetics, business.industry, fungi, Surgery, Obesity, Morbid, One-way analysis of variance, Treatment Outcome, 030211 gastroenterology & hepatology, medicine.symptom, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7303530a967c4137c7c7797398d1cf4f
https://pubmed.ncbi.nlm.nih.gov/31898046

المؤلفون: Nita A. Limdi, James K. Burmester, Esteban J. Parra, Todd A. Johnson, S. Krithika, Tatsuhiko Tsunoda, Larisa H. Cavallari, Mara H. Hutz, Guilherme Suarez-Kurtz, Mia Wadelius, Mariana R. Botton, Jamila Alessandra Perini, Teri E. Klein, Allan E. Rettie, Julie A. Johnson, Munir Pirmohamed, Stephane Bourgeois

المصدر: Pharmacogenomics. 16:1253-1263

مصطلحات موضوعية: Male, Oncology, medicine.medical_specialty, Genotype, Genome-wide association study, Bioinformatics, Polymorphism, Single Nucleotide, Article, Vitamin K Epoxide Reductases, Internal medicine, Genetics, medicine, Humans, SNP, 1000 Genomes Project, CYP2C9, Aged, Cytochrome P-450 CYP2C9, Pharmacology, business.industry, Maintenance dose, Warfarin, Anticoagulants, Middle Aged, Phenotype, Molecular Medicine, Female, VKORC1, business, Brazil, Imputation (genetics), Genome-Wide Association Study, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07481390d3b52b4b03b0a29228601b7
https://doi.org/10.2217/pgs.15.73

المؤلفون: Ana Alfirevic, Panagiotis Deloukas, Andrea L. Jorgensen, Ulrich M. Zanger, Kathrin Klein, Stephane Bourgeois, Jieying Eunice Zhang, Ben Francis, Munir Pirmohamed

المصدر: Frontiers in Pharmacology, Vol 8 (2017)
FRONTIERS IN PHARMACOLOGY

مصطلحات موضوعية: 0301 basic medicine, CYP4F2, Single-nucleotide polymorphism, Genome-wide association study, Biology, 030226 pharmacology & pharmacy, 03 medical and health sciences, CYP4F11, 0302 clinical medicine, Gene cluster, CYP4F12, Pharmacology (medical), Genetic variability, 10. No inequality, pharmacogenetics, 2. Zero hunger, Clotting factor, Genetics, Pharmacology, lcsh:RM1-950, mRNA expression, 3. Good health, warfarin, 030104 developmental biology, lcsh:Therapeutics. Pharmacology, VKORC1

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27bab8353d4f39f935517133d9d170ad
http://journal.frontiersin.org/article/10.3389/fphar.2017.00323/full