المؤلفون: Simone M. Schoenwaelder, Roxane Darbousset, Susan L. Cranmer, Hayley S. Ramshaw, Stephanie L. Orive, Sharelle Sturgeon, Yuping Yuan, Yu Yao, James R. Krycer, Joanna Woodcock, Jessica Maclean, Stuart Pitson, Zhaohua Zheng, Darren C. Henstridge, Dianne van der Wal, Elizabeth E. Gardiner, Michael C. Berndt, Robert K. Andrews, David E. James, Angel F. Lopez, Shaun P. Jackson

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/b523399dd63e458a9df758471882f328

المؤلفون: Simone M. Schoenwaelder, Roxane Darbousset, Susan L. Cranmer, Hayley S. Ramshaw, Stephanie L. Orive, Sharelle Sturgeon, Yuping Yuan, Yu Yao, James R. Krycer, Joanna Woodcock, Jessica Maclean, Stuart Pitson, Zhaohua Zheng, Darren C. Henstridge, Dianne van der Wal, Elizabeth E. Gardiner, Michael C. Berndt, Robert K. Andrews, David E. James, Angel F. Lopez, Shaun P. Jackson

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-2 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/f168642eebdb4dac8195ddf78e7109ea

المؤلفون: Diego Chacon, Sung K. Chiu, David J. Curtis, Mitchell J. Moon, Stephanie L. Orive, Justin Raymond Hamilton, Cedric S. Tremblay, John E. Pimanda, Dominik Beck, Benjamin T. Kile, Sarah Ellis, Yizhou Huang, Jesslyn Saw

المصدر: Blood. 134:826-835

مصطلحات موضوعية: fungi, Immunology, Impaired platelet aggregation, Transcription factor complex, GATA1, Cell Biology, Hematology, Biology, Biochemistry, Cell biology, medicine.anatomical_structure, Megakaryocyte, hemic and lymphatic diseases, medicine, Thrombopoiesis, Platelet factor 4, Megakaryopoiesis, Megakaryocytopoiesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::11f43754370f32a2fbe314b63d983459
https://doi.org/10.1182/blood.2019896175

المؤلفون: David M. Shackleford, Philip E. Thompson, Ian G. Jennings, Simone M. Schoenwaelder, Simon J. Mountford, Andrew K. Powell, Justin Raymond Hamilton, Jo-Anne Pinson, Shaun P. Jackson, Zhaohua Zheng, Stephanie L. Orive, Erin M. Nelson

المصدر: European Journal of Medicinal Chemistry. 122:339-351

مصطلحات موضوعية: Male, 0301 basic medicine, Platelet Aggregation, Integrin, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, In vivo, Morpholine, Drug Discovery, Animals, Humans, Enzyme Inhibitors, Site-directed mutagenesis, Phosphoinositide-3 Kinase Inhibitors, ADME, Pharmacology, biology, Triazines, Organic Chemistry, General Medicine, In vitro, Rats, 030104 developmental biology, Biochemistry, chemistry, 030220 oncology & carcinogenesis, biology.protein, Biophysics, Platelet aggregation inhibitor, Selectivity, Platelet Aggregation Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ade3ebd9ed59ca9a1a6e7b40816ba3
https://doi.org/10.1016/j.ejmech.2016.06.010

المؤلفون: Sung K, Chiu, Stephanie L, Orive, Mitchell J, Moon, Jesslyn, Saw, Sarah, Ellis, Benjamin T, Kile, Yizhou, Huang, Diego, Chacon, John E, Pimanda, Dominik, Beck, Justin R, Hamilton, Cedric S, Tremblay, David J, Curtis

المصدر: Blood. 134(10)

مصطلحات موضوعية: Blood Platelets, Mice, Knockout, Mice, Gene Expression Regulation, Basic Helix-Loop-Helix Transcription Factors, Animals, GATA1 Transcription Factor, Mice, Transgenic, Megakaryocytes, Thrombocytopenia, T-Cell Acute Lymphocytic Leukemia Protein 1, Neoplasm Proteins, Thrombopoiesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::ad66cc47f6931fd73ce6b2fdc05c01ca
https://pubmed.ncbi.nlm.nih.gov/31488457

المؤلفون: Rick Morrison, Justin Raymond Hamilton, Philip E. Thompson, Zhaohua Zheng, Stephanie L. Orive, Saifuzzaman, Jasim M. A. Al-Rawi

المصدر: Bioorganicmedicinal chemistry. 25(20)

مصطلحات موضوعية: Steric effects, Platelet Aggregation, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, DNA-Activated Protein Kinase, 010402 general chemistry, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Phosphatidylinositol 3-Kinases, Structure-Activity Relationship, Suzuki reaction, Drug Discovery, Humans, Molecular Biology, Protein Kinase Inhibitors, Phosphoinositide-3 Kinase Inhibitors, chemistry.chemical_classification, Atropisomer, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Aryl, Organic Chemistry, Active site, Cyclic Nucleotide Phosphodiesterases, Type 3, 0104 chemical sciences, Benzoxazines, Williamson ether synthesis, Enzyme, chemistry, Axial chirality, biology.protein, Molecular Medicine, Platelet Aggregation Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5e6abbb2af6f0bdf8c7cb3eae8e059
https://pubmed.ncbi.nlm.nih.gov/28838830

المؤلفون: Stuart M. Pitson, Elizabeth E. Gardiner, Shaun P. Jackson, Darren C. Henstridge, Jessica Maclean, James R. Krycer, Simone M. Schoenwaelder, Joanna M. Woodcock, Susan L. Cranmer, Hayley S. Ramshaw, Michael C. Berndt, Stephanie L. Orive, Dianne E. van der Wal, Robert K. Andrews, Yu Yao, Yuping Yuan, Zhaohua Zheng, Roxane Darbousset, Sharelle Anne Sturgeon, Angel F. Lopez, David E. James

المساهمون: Schoenwaelder, Simon M, Darbousset, Roxane, Cranmer, Susan L, Ramshaw, Hayley S, Woodcock, Joanna, Pitson, Stuart, Lopez, Angel F, Jackson, Shaun P

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Science, mitochondrial respiratory, General Physics and Astronomy, Mitochondrion, General Biochemistry, Genetics and Molecular Biology, 14-3-3ζ, 03 medical and health sciences, chemistry.chemical_compound, Von Willebrand factor, Internal medicine, Thrombin receptor, medicine, Platelet, Platelet activation, Multidisciplinary, biology, General Chemistry, Phosphatidylserine, 3. Good health, 030104 developmental biology, Endocrinology, Coagulation, chemistry, Apoptosis, Immunology, platelets, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1037d7057135ecf7dc90c1a15453c5
https://hdl.handle.net/11541.2/122346

المؤلفون: Jessica Maclean, Hayley S. Ramshaw, Robert K. Andrews, Stuart M. Pitson, Joanna M. Woodcock, Roxane Darbousset, David E. James, Yuping Yuan, Elizabeth E. Gardiner, Susan L. Cranmer, Darren C. Henstridge, Simone M. Schoenwaelder, Michael C. Berndt, Angel F. Lopez, Stephanie L. Orive, Sharelle Anne Sturgeon, James R. Krycer, Shaun P. Jackson, Dianne E. van der Wal, Zhaohua Zheng, Yu Yao

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-2 (2017)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Phosphatidylserine exposure, medicine.medical_specialty, Multidisciplinary, Chemistry, Science, General Physics and Astronomy, 02 engineering and technology, General Chemistry, 021001 nanoscience & nanotechnology, Corrigenda, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, 030104 developmental biology, Endocrinology, Internal medicine, medicine, Platelet, Respiratory system, 0210 nano-technology, Function (biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85dc13fadde512e7dbcbf98607a24225
https://doaj.org/article/f168642eebdb4dac8195ddf78e7109ea