المؤلفون: Besma Benredjem, Jonathan Gallion, Dennis Pelletier, Paul Dallaire, Johanie Charbonneau, Darren Cawkill, Karim Nagi, Mark Gosink, Viktoryia Lukasheva, Stephen Jenkinson, Yong Ren, Christopher Somps, Brigitte Murat, Emma Van Der Westhuizen, Christian Le Gouill, Olivier Lichtarge, Anne Schmidt, Michel Bouvier, Graciela Pineyro

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/c0db3f1cf110426bbd5f35d40fd3681b

المؤلفون: Leigh Stoddart, Amy E. Monaghan, Graeme Milligan, Stephen Jenkinson, Nick Holliday, Andrew Brown, Celia Briscoe

المصدر: IUPHAR/BPS Guide to Pharmacology CITE. 2023

مصطلحات موضوعية: General Medicine, General Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d8a41588487112160701291d40b9ceb8
https://doi.org/10.2218/gtopdb/f24/2023.1

المؤلفون: Besma Benredjem, Jonathan Gallion, Dennis Pelletier, Paul Dallaire, Johanie Charbonneau, Darren Cawkill, Karim Nagi, Mark Gosink, Viktoryia Lukasheva, Stephen Jenkinson, Yong Ren, Christopher Somps, Brigitte Murat, Emma Van Der Westhuizen, Christian Le Gouill, Olivier Lichtarge, Anne Schmidt, Michel Bouvier, Graciela Pineyro

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/1f09235de66f4fc295108bc582f6d396

المؤلفون: Jean G. Sathish, Siddhartha Bhatt, Jamie K. DaSilva, Declan Flynn, Stephen Jenkinson, Amit S. Kalgutkar, Maggie Liu, Balasubramanian Manickam, Jason Pinkstaff, William J. Reagan, Norimitsu Shirai, Ahmed M. Shoieb, Madhu Sirivelu, Saurabh Vispute, Allison Vitsky, Karen Walters, Todd A. Wisialowski, Lawrence W. Updyke

المصدر: International journal of toxicology. 41(4)

مصطلحات موضوعية: Male, Animals, Toxicology, Antiviral Agents, Rats, COVID-19 Drug Treatment

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea1a7a89320457f06d9cf5a899cc71f
https://pubmed.ncbi.nlm.nih.gov/35603517

المؤلفون: Nicolas Couvreur, Charles Benson, Jean-Michel Guillon, Yoshiko Okai, Armando Lagrutta, Todd Wisialowski, Michael G. Rolf, Ard Teisman, C. Michael Foley, Hugo M. Vargas, Jean-Pierre Valentin, Maki Ito, Michael J. Engwall, Khuram W. Chaudhary, Gary Gintant, David J. Gallacher, Takashi Yoshinaga, Andrea Greiter-Wilke, Corina Dota, Paul Levesque, Katsuyoshi Chiba, Amy Pointon, Stephen Jenkinson, Anthony Bahinski, Martin Traebert, Brian Guth, Eric Martel, Alan S. Bass, Christa Hegele‐Hartung, William E. Achanzar, Ravikumar Peri, Herbert M. Himmel, Yusheng Qu, Derek J. Leishman

المصدر: Clinical Pharmacology and Therapeutics

مصطلحات موضوعية: Drug, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Drug Industry, media_common.quotation_subject, Decision Making, hERG, Drug Evaluation, Preclinical, Reviews, Torsades de pointes, Review, Risk Assessment, 030226 pharmacology & pharmacy, QT interval, Electrocardiography, 03 medical and health sciences, 0302 clinical medicine, Drug Development, Torsades de Pointes, medicine, Animals, Humans, Repolarization, Pharmacology (medical), cardiovascular diseases, Intensive care medicine, media_common, Pharmacology, biology, Surrogate endpoint, business.industry, Arrhythmias, Cardiac, Drugs, Investigational, medicine.disease, nervous system diseases, Clinical trial, Long QT Syndrome, Drug development, 030220 oncology & carcinogenesis, biology.protein, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::527f989fd8c7a31101405fa082c754d4
https://doi.org/10.1002/cpt.2029

المؤلفون: Dennis Hyek, Jinshan Chen, R. Scott Obach, Melissa Wagenaar, Mark W. Bundesmann, Asser Bassyouni, Jeremy T. Starr, Maria S. Brown, Stephen Jenkinson, Manjinder S. Lall, Gregory Ciszewski, James Bradow, Gregory S. Walker, Senliang Pan, Douglas K. Spracklin, Bo Liu, Neal W. Sach, Daniel J Smaltz, Anne E. Hagen, Usa Reilly

المصدر: Journal of Medicinal Chemistry. 63:7268-7292

مصطلحات موضوعية: 0303 health sciences, Chemistry, Nuclear magnetic resonance spectroscopy, Histamine H1 receptor, Loratadine, Histamine H1 Antagonists, Tandem mass spectrometry, 01 natural sciences, Combinatorial chemistry, Chemical space, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Drug Discovery, medicine, Molecular Medicine, Structure–activity relationship, Inverse agonist, 030304 developmental biology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4a4f2cd830cd5ca3994e400969ad8fd2
https://doi.org/10.1021/acs.jmedchem.0c00483

المؤلفون: Stephen Jenkinson, Jonathan Gallion, Darren Cawkill, Brigitte Murat, Olivier Lichtarge, Yong Ren, Michel Bouvier, Karim Nagi, Emma T van der Westhuizen, Christian Le Gouill, Besma Benredjem, Viktoryia Lukasheva, Johanie Charbonneau, Paul Dallaire, Mark Gosink, Anne W. Schmidt, Christopher Somps, Dennis J. Pelletier, Graciela Piñeyro

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Signaling profiles, Computer science, Science, Guinea Pigs, Receptors, Opioid, mu, General Physics and Astronomy, Computational biology, Ligands, Bias signaling, General Biochemistry, Genetics and Molecular Biology, GPCRs, Clustering, Article, Receptors, G-Protein-Coupled, Food and drug administration, 03 medical and health sciences, 0302 clinical medicine, GTP-Binding Proteins, Animals, Cluster Analysis, Humans, Clinical responses, Cluster analysis, lcsh:Science, Author Correction, beta-Arrestins, G protein-coupled receptor, Pharmacology, Multidisciplinary, Ligand, Effector, General Chemistry, 3. Good health, Computational biology and bioinformatics, Analgesics, Opioid, 030104 developmental biology, HEK293 Cells, Drug screening, Classification methods, lcsh:Q, Receptors, Adrenergic, beta-2, Signal transduction, Unsupervised clustering, 030217 neurology & neurosurgery, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57762958730e340da6b5d5094174a386
https://doaj.org/article/c0db3f1cf110426bbd5f35d40fd3681b

المؤلفون: Eric D, Watt, Tiffany, Lee, Shuyun Lily, Feng, Peter, Kilfoil, David, Ackley, Christopher, Keefer, Todd, Wisialowski, Stephen, Jenkinson

المصدر: Journal of Pharmacological and Toxicological Methods. 118:107213

مصطلحات موضوعية: DNA-Binding Proteins, Pharmacology, ERG1 Potassium Channel, Torsades de Pointes, Humans, Reproducibility of Results, Arrhythmias, Cardiac, Toxicology, Ether-A-Go-Go Potassium Channels, Ion Channels, Retrospective Studies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16565e459dea8ca183651ac33c68617a
https://doi.org/10.1016/j.vascn.2022.107213

المؤلفون: Stephen Jenkinson, Dingzhou Li, David J. MacEwan, Peter Kilfoil, Eric D. Watt, Derek J. Leishman, Parveen Sharma, Tiffany Lee, Asser Bassyouni, Shuyun Lily Feng

المصدر: European Journal of Pharmacology

مصطلحات موضوعية: Drug, media_common.quotation_subject, hERG, Induced Pluripotent Stem Cells, Action Potentials, Torsades de pointes, Pharmacology, QT interval, Models, Biological, QRS complex, Electrocardiography, Torsades de Pointes, Medicine, Humans, Myocytes, Cardiac, Induced pluripotent stem cell, Correlation of Data, Cells, Cultured, media_common, biology, business.industry, medicine.disease, Calcium Channel Blockers, High-Throughput Screening Assays, Drug development, ROC Curve, biology.protein, Stem cell, business, Transcriptome, Sodium Channel Blockers

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354b5671ca62b0aeeb7522f5069bc852
https://pubmed.ncbi.nlm.nih.gov/34678241

المؤلفون: Jean-Pierre Valentin, Lyn Rosenbrier-Ribeiro, Stephen Jenkinson, Jean-Michel Guillon, Sonia Roberts, Duncan Armstrong, Friedemann Schmidt, Vivek J. Kadambi, Peri Ravikumar

المصدر: Journal of Pharmacological and Toxicological Methods. 93:7-14

مصطلحات موضوعية: 0301 basic medicine, Drug Industry, Drug-Related Side Effects and Adverse Reactions, Computer science, Drug Evaluation, Preclinical, Toxicology, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Surveys and Questionnaires, Drug Discovery, Humans, Profiling (information science), Pharmaceutical industry, Pharmacology, Potential risk, business.industry, Drug discovery, In vitro toxicology, Data interpretation, Service provider, Quality Improvement, Data science, 030104 developmental biology, Therapeutic Area, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a766feee1296600d39053f3d781fb9a1
https://doi.org/10.1016/j.vascn.2018.07.001