المؤلفون: Nicolas Deconinck, Steve S Hood, Haluk Topaloglu, Lia Liefaard, C. Wardell, Rosamund Wilson, Sjef J. de Kimpe, John E. Kraus, Michelle Eagle, Katie Rolfe, Laurent Servais, Joanna Nakielny, Afrodite Lourbakos, Michela Guglieri, Valeria Ricotti, Giles G Campion, Allison A Morgan, Francesco Muntoni, Volker Straub, Padraig Wright, Thomas Voit, Naashika Quarcoo

المصدر: The Lancet Neurology. 13:987-996

مصطلحات موضوعية: Male, medicine.medical_specialty, Duchenne muscular dystrophy, Population, Anti-Inflammatory Agents, Oligonucleotides, Walking, Real-Time Polymerase Chain Reaction, Eteplirsen, Placebo, law.invention, Dystrophin, Double-Blind Method, Randomized controlled trial, Adrenal Cortex Hormones, law, Internal medicine, Clinical endpoint, medicine, Humans, Child, education, Adverse effect, Drisapersen, education.field_of_study, business.industry, Exons, medicine.disease, Muscular Dystrophy, Duchenne, Treatment Outcome, Area Under Curve, Child, Preschool, Physical therapy, Female, Neurology (clinical), business, Gene Deletion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4376b8b1e340ad1c94d88d59dcefb3a3
https://doi.org/10.1016/s1474-4422(14)70195-4

المؤلفون: Bodger K; Department of Health Data Science, Institute of Population Health, University of Liverpool, Liverpool, UK kbodger@liverpool.ac.uk.; Gastroenterology Department, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Mair T; Department of Health Data Science, Institute of Population Health, University of Liverpool, Liverpool, UK., Schofield P; Department of Public Health & Policy, University of Liverpool, Liverpool, UK., Silberberg B; Department of Health Data Science, Institute of Population Health, University of Liverpool, Liverpool, UK., Hood S; Gastroenterology Department, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Fleming KM; Data & Analytics Transformation Directorate, NHS England, Redditch, UK.

المصدر: BMJ open [BMJ Open] 2023 Nov 22; Vol. 13 (11), pp. e076955. Date of Electronic Publication: 2023 Nov 22.

نوع المنشور: Observational Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE

مواضيع طبية MeSH: Liver Diseases*/epidemiology , Liver Diseases*/therapy , Alcohol-Related Disorders*/epidemiology , Alcohol-Related Disorders*/therapy, Humans ; Female ; Middle Aged ; Male ; Retrospective Studies ; Hospital Mortality ; Hospitalization ; Electronics

المؤلفون: Parker R; Leeds Liver Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK richardparker@nhs.net.; Leeds Institute of Medical Research at St James's University Hospital, University of Leeds, Leeds, UK., Allison M; Cambridge Liver Unit, Addenbrooke's Hospital, Cambridge, UK., Anderson S; Angus Integrated Drug and Alcohol Recovery Service (AIDARS), Ninewells Hospital and Medical School, Dundee, UK., Aspinall R; Gastroenterology & Hepatology, Portsmouth Hospitals NHS Trust, Portsmouth, UK., Bardell S; Birmingham Liver Services Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Bains V; Liver Transplant Unit, King's College Hospital NHS Foundation Trust, London, UK., Buchanan R; Faculty of Medicine, University of Southampton, Southampton, UK., Corless L; Department of Gastroenterology, Hepatology and Endoscopy, Hull University Teaching Hospitals NHS Trust, Hull, UK., Davidson I; NHS Fife Addiction Services, NHS Fife, Kirkcaldy, UK., Dundas P; Peter Brunt Centre, Aberdeen Royal Infirmary, NHS Grampian, Aberdeen, UK., Fernandez J; Alcohol and Drug Liaison, Royal Free London NHS Foundation Trust, London, UK., Forrest E; Dept of Gastroenterology, Glasgow Royal Infirmary, Glasgow, UK., Forster E; Leeds Liver Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK., Freshwater D; Birmingham Liver Services Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Gailer R; Islington Primary Care Federation, London, UK., Goldin R; Department of Digestive Diseases, Department of Medicine, Imperial College London, London, UK., Hebditch V; British Liver Trust, Ringwood, UK., Hood S; Digestive Diseases Unit, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Jones A; Pharmacy, Barts and The London NHS Trust, London, UK., Lavers V; Independent researcher, Plymouth, UK., Lindsay D; Alcohol Care Team, East Lancashire Hospitals NHS Trust, Blackburn, UK., Maurice J; Gastroenterology and hepatology, North Bristol NHS Trust, Westbury on Trym, UK., McDonagh J; Birmingham Liver Services Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Morgan S; Hampstead Group Practice, London, UK., Nurun T; Department of Gastroenterology, Hepatology and Endoscopy, Hull University Teaching Hospitals NHS Trust, Hull, UK., Oldroyd C; Cambridge Liver Unit, Addenbrooke's Hospital, Cambridge, UK., Oxley E; St Martins Practice, Leeds, UK., Pannifex S; Hepatology, St George's Healthcare NHS Trust, London, UK., Parsons G; Hepatology, Plymouth Hospitals NHS Trust, Plymouth, UK., Phillips T; Faculty of Health Sciences, University of Hull, Hull, UK., Rainford N; Liver Transplant Unit, King's College Hospital NHS Foundation Trust, London, UK., Rajoriya N; Birmingham Liver Services Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Richardson P; Gastroenterology and Hepatology, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK., Ryan J; Sheila Sherlock Liver Centre, Royal Free London NHS Foundation Trust, London, UK., Sayer J; Gastroenterology, Doncaster and Bassetlaw Hospitals NHS Foundation Trust, Doncaster, UK., Smith M; Alcohol care team, Southport and Ormskirk Hospital NHS Trust, Southport, UK., Srivastava A; Gastroenterology and hepatology, North Bristol NHS Trust, Westbury on Trym, UK., Stennett E; Gastroenterology, Guy's and St Thomas' Hospitals NHS Trust, London, UK., Towey J; Birmingham Liver Services Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Vaziri R; Humankind, Durham, UK., Webzell I; Liver Transplant Unit, King's College Hospital NHS Foundation Trust, London, UK., Wellstead A; Gastroenterology, University Hospitals Dorset NHS Foundation Trust, Poole, UK., Dhanda A; Faculty of health, University of Plymouth, Plymouth, UK., Masson S; Liver unit, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK.

المصدر: BMJ open gastroenterology [BMJ Open Gastroenterol] 2023 Oct; Vol. 10 (1).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BMJ Publishing Group Ltd & British Society of Gastroenterology Country of Publication: England NLM ID: 101660690 Publication Model: Print Cited Medium: Print ISSN: 2054-4774 (Print) Linking ISSN: 20544774 NLM ISO Abbreviation: BMJ Open Gastroenterol Subsets: MEDLINE

مواضيع طبية MeSH: Gastroenterology* , Liver Diseases*/therapy, Humans ; Consensus ; Public Opinion

المؤلفون: Christensen JK; Development ADME, Novo Nordisk A/S, Måløv, Denmark., Bjørnsdottir I; Development ADME, Novo Nordisk A/S, Måløv, Denmark., Sonesson A; Global DMPK, Copenhagen, Denmark., Hood S; In Vitro/In Vivo Translation, Research, Stevenage, GlaxoSmithKline, UK.

المصدر: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2023 Apr; Vol. 53 (4), pp. 332-337. Date of Electronic Publication: 2023 Jun 19.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE

مواضيع طبية MeSH: Peptides*/metabolism, Drug Interactions ; Metabolic Clearance Rate

المؤلفون: Woodhouse N; School of Physics and Astronomy, 6123University of Nottingham, Nottingham, UK., Majer J; 113460GlaxoSmithKline, Stevenage, UK., Marshall P; 113460GlaxoSmithKline, Stevenage, UK., Hood S; 113460GlaxoSmithKline, Stevenage, UK., Notingher I; School of Physics and Astronomy, 6123University of Nottingham, Nottingham, UK.

المصدر: Applied spectroscopy [Appl Spectrosc] 2023 Mar; Vol. 77 (3), pp. 246-260. Date of Electronic Publication: 2022 Nov 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Sage Country of Publication: United States NLM ID: 0372406 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-3530 (Electronic) Linking ISSN: 00037028 NLM ISO Abbreviation: Appl Spectrosc Subsets: MEDLINE

مواضيع طبية MeSH: Spectrum Analysis, Raman*/methods , Liver*, Pharmaceutical Preparations ; Brain ; Alkynes

المؤلفون: Dhanda A; University of Plymouth, Plymouth, UK.; South West Liver Unit, University Hospitals Plymouth NHS Trust, Plymouth, UK., Bodger K; University of Liverpool, Liverpool, UK.; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Hood S; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Henn C; Addiction and Inclusion Directorate, Office for Health Improvement and Disparities, Department for Health and Social Care, London, UK., Allison M; Cambridge Liver Unit, Cambridge NIHR Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Amasiatu C; Addiction and Inclusion Directorate, Office for Health Improvement and Disparities, Department for Health and Social Care, London, UK., Burton R; Addiction and Inclusion Directorate, Office for Health Improvement and Disparities, Department for Health and Social Care, London, UK., Cramp M; University of Plymouth, Plymouth, UK.; South West Liver Unit, University Hospitals Plymouth NHS Trust, Plymouth, UK., Forrest E; Glasgow Royal Infirmary, Glasgow, UK., Khetani M; Addiction and Inclusion Directorate, Office for Health Improvement and Disparities, Department for Health and Social Care, London, UK., MacGilchrist A; Liver Unit, Royal Infirmary of Edinburgh, NHS Lothian, Edinburgh, UK., Masson S; Liver Unit, Newcastle Hospitals NHS Trust, Newcastle, UK., Parker R; Leeds Liver Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK., Sheron N; Addiction and Inclusion Directorate, Office for Health Improvement and Disparities, Department for Health and Social Care, London, UK., Simpson K; Liver Unit, Royal Infirmary of Edinburgh, NHS Lothian, Edinburgh, UK., Vergis N; Imperial College London, London, UK.; Research and Development, GlaxoSmithKline (GSK), Hertfordshire, UK., White M; Addiction and Inclusion Directorate, Office for Health Improvement and Disparities, Department for Health and Social Care, London, UK.

مؤلفون مشاركون: BASL ARLD SIG National Service Evaluation Group

المصدر: Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2023 Feb; Vol. 57 (4), pp. 368-377. Date of Electronic Publication: 2022 Nov 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 8707234 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2036 (Electronic) Linking ISSN: 02692813 NLM ISO Abbreviation: Aliment Pharmacol Ther Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19*/epidemiology , Liver Diseases*/diagnosis , Liver Diseases*/epidemiology, Humans ; Pandemics ; Hospitalization ; Hospitals ; England/epidemiology ; Algorithms

المؤلفون: Han K; GSK, Collegeville, Pennsylvania, USA., Ito H; GSK K.K., Tokyo, Japan., Elston R; GSK, Stevenage, United Kingdom., Cremer J; GSK, Durham, North Carolina, USA., Hood S; GSK, Stevenage, United Kingdom., Paff M; GSK, Collegeville, Pennsylvania, USA., Theodore D; GSK, Durham, North Carolina, USA.

المصدر: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2023 Jan 24; Vol. 67 (1), pp. e0090022. Date of Electronic Publication: 2022 Dec 12.

نوع المنشور: Randomized Controlled Trial; Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

مواضيع طبية MeSH: Oligonucleotides, Antisense*/therapeutic use , Hepatitis B, Chronic*/drug therapy, Humans ; Area Under Curve ; China ; Hong Kong ; Double-Blind Method

المؤلفون: Han K; GSK, Collegeville, Pennsylvania, USA., Theodore D; GSK, Durham, North Carolina, USA., McMullen G; Ionis Pharmaceuticals Inc., Carlsbad, California, USA., Swayze E; Ionis Pharmaceuticals Inc., Carlsbad, California, USA., McCaleb M; Ionis Pharmaceuticals Inc., Carlsbad, California, USA., Billioud G; The Scripps Research Institute, La Jolla, California, USA., Wieland S; The Scripps Research Institute, La Jolla, California, USA., Hood S; GSK, Stevenage, UK., Paff M; GSK, Collegeville, Pennsylvania, USA., Bennett CF; Ionis Pharmaceuticals Inc., Carlsbad, California, USA., Kwoh TJ; Ionis Pharmaceuticals Inc., Carlsbad, California, USA.

المصدر: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2022 Oct; Vol. 11 (10), pp. 1191-1202. Date of Electronic Publication: 2022 Aug 16.

نوع المنشور: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2160-7648 (Electronic) Linking ISSN: 2160763X NLM ISO Abbreviation: Clin Pharmacol Drug Dev Subsets: MEDLINE

مواضيع طبية MeSH: Hepatitis B virus*/genetics , Oligonucleotides, Antisense*, Animals ; Antiviral Agents ; Double-Blind Method ; Humans ; Mice ; Mice, Transgenic ; RNA ; Viral Proteins

المؤلفون: Hood S; Department of Research, In Vitro/In Vivo Translation, GlaxoSmithKline, Stevenage, UK., Kenworthy D; Department of Research, In Vitro/In Vivo Translation, GlaxoSmithKline, Stevenage, UK., Christensen JK; Development ADME, Novo Nordisk A/S, Måløv, Denmark.

المصدر: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2022 Aug; Vol. 52 (8), pp. 957-961. Date of Electronic Publication: 2022 Sep 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE

مواضيع طبية MeSH: Oligonucleotides*/therapeutic use, Pharmaceutical Preparations/metabolism

المؤلفون: Taylor S; Pharmaron UK, Hoddesdon, UK., Henshall J; Development Science, UCB Biopharma SRL, Slough, UK., Beaumont K; Early Oncology DMPK, Astrazeneca, Little Chesterford, UK., Hood S; GSK Medicines Research Centre, Stevenage, UK., Jones B; Pharmaron UK, Hoddesdon, UK., Wilson I; Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK., Smith D; Independent, Walmer, UK.

المصدر: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2022 Aug; Vol. 52 (8), pp. 767-769.

نوع المنشور: Historical Article; Journal Article

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: PubMed not MEDLINE; MEDLINE