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المؤلفون: Simon J F, Macdonald, Geoffrey D E, Clarke, Michael D, Dowle, Lee A, Harrison, Simon T, Hodgson, Graham G A, Inglis, Martin R, Johnson, Prit, Shah, Richard J, Upton, Steven B, Walls
المصدر: The Journal of organic chemistry. 64(14)
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المصدر: European Journal of Organic Chemistry. 2006:323-327
مصطلحات موضوعية: chemistry.chemical_classification, Allylic rearrangement, Stereochemistry, Organic Chemistry, General Medicine, Ring (chemistry), Cycloaddition, Catalysis, chemistry, Ylide, Stereoselectivity, Physical and Theoretical Chemistry, Oxonium ion, Carbenoid
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المؤلفون: Simon J. F. Macdonald, Geoffrey D. Clarke, Michael Dennis Dowle, Martin R. Johnson, Graham G. A. Inglis, Prit Shah, Richard J. Upton, Lee Andrew Harrison, Steven B. Walls, Simon Teanby Hodgson
المصدر: The Journal of Organic Chemistry. 64:5166-5175
مصطلحات موضوعية: chemistry.chemical_compound, Silylation, chemistry, Stereochemistry, Organic Chemistry, Acetal, Ketene, Amine gas treating, Stereoselectivity, Lewis acids and bases, Pyrrolidine, Stereocenter
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المؤلفون: Hart Terance William, Rachel Parsons, Ben Gibbons, Helen Browne, Macias Alba, Heather Simmonite, Sarah Dugdale, Sean Lightowler, Howard Langh Am Mansell, Guy A. Kennett, Anthony Padfield, Geraint L. Francis, Robert M. Pratt, Teresa Brooks, Timothy Haymes, Jalanie D’Alessandro, Natalia Matassova, K Benwell, Melanie Wong, Steven B. Walls, Stephen D. Roughley, A Misra, Zoe Daniels, Angela Merrett, Alan D. Robertson, Kiri Tan
المصدر: Bioorganicmedicinal chemistry letters. 22(2)
مصطلحات موضوعية: Models, Molecular, ERG1 Potassium Channel, Stereochemistry, Clinical Biochemistry, Azetidine, Pharmaceutical Science, Stereoisomerism, Biochemistry, Amidohydrolases, chemistry.chemical_compound, Structure-Activity Relationship, Cytochrome P-450 Enzyme System, Fatty acid amide hydrolase, In vivo, Drug Discovery, Structure–activity relationship, Animals, Cytochrome P-450 Enzyme Inhibitors, Humans, Urea, Enzyme Inhibitors, Molecular Biology, Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, Anandamide, Ether-A-Go-Go Potassium Channels, Rats, nervous system, chemistry, Molecular Medicine, Azetidines, lipids (amino acids, peptides, and proteins), psychological phenomena and processes
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المؤلفون: Brian Dymock, Allan E. Surgenor, Joseph Schoepfer, Christophe Fromont, Carlos Garcia-Echeverria, Suzanne A. Eccles, Angela Hayes, Melanie Valenti, Paul Brough, Angela Merrett, Roderick E. Hubbard, Nicholas G. M. Davies, Martin J. Drysdale, Michael Rugaard Jensen, Heather Simmonite, Thomas Radimerski, Andrew Massey, Allan M. Jordan, Alan D. Robertson, Michael Wood, Lisa Wright, Patrick Chène, Florence I. Raynaud, Paul Webb, Steven B. Walls, Swee Y. Sharp, Paul Workman, Ben Davis, Xavier Barril, Antony Padfield, Stephen D. Roughley, Rachel Parsons, Jenifer Borgognoni
المصدر: Journal of medicinal chemistry. 52(15)
مصطلحات موضوعية: Male, Molecular model, In silico, Administration, Oral, Antineoplastic Agents, Fluorescence Polarization, Crystallography, X-Ray, Binding, Competitive, Mice, Drug Discovery, Animals, Humans, HSP90 Heat-Shock Proteins, IC50, chemistry.chemical_classification, Mice, Inbred BALB C, biology, Chemistry, Cell growth, Hsp90, Xenograft Model Antitumor Assays, Enzyme, Pyrimidines, Biochemistry, Enzyme inhibitor, Chaperone (protein), biology.protein, Molecular Medicine, Female
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المؤلفون: Alan Robertson, Guy A. Kennett, Stephen D. Roughley, Geraint L. Francis, K Benwell, Melanie Wong, Rachel Parsons, A Misra, Timothy Haymes, Hart Terance William, Howard Langh Am Mansell, Macias Alba, Anthony Padfield, Sean Lightowler, Jalanie D’Alessandro, Natalia Matassova, Ben Gibbons, Teresa Brooks, Steven B. Walls, Robert M. Pratt, Pawel Dokurno
المصدر: Bioorganicmedicinal chemistry letters. 19(15)
مصطلحات موضوعية: Stereochemistry, Chemistry, Pharmaceutical, Clinical Biochemistry, Azetidine, Pharmaceutical Science, Ether, Stereoisomerism, Biochemistry, Catalysis, Amidase, Amidohydrolases, chemistry.chemical_compound, Mice, Piperidines, Receptor, Cannabinoid, CB1, Fatty acid amide hydrolase, Drug Discovery, Animals, Humans, Urea, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Mice, Knockout, biology, Organic Chemistry, Rats, Enzyme, nervous system, chemistry, Models, Chemical, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Azetidines, lipids (amino acids, peptides, and proteins), Selectivity, psychological phenomena and processes
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