المؤلفون: Joseph Leedale, Kieran J. Sharkey, Helen E. Colley, Áine M. Norton, David Peeney, Chantelle L. Mason, Jean G. Sathish, Craig Murdoch, Parveen Sharma, Steven D. Webb

المصدر: iScience, Vol 4, Iss , Pp 84-96 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004218300671; https://doaj.org/toc/2589-0042

URL الوصول: https://doaj.org/article/7a4f13c9f84141ecb44712980aa71c4a

المؤلفون: Lauren Tomlinson, Zhen Qi Lu, Robert A Bentley, Helen E. Colley, Craig Murdoch, Steven D. Webb, Michael J. Cross, Ian M. Copple, Parveen Sharma

المصدر: Biomedicine & Pharmacotherapy, Vol 112, Iss , Pp - (2019)

مصطلحات موضوعية: Cardiotoxicity, NRF2, 3D models, Anthracycline, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0753332218360955; https://doaj.org/toc/0753-3322

URL الوصول: https://doaj.org/article/0819abf2d1dc48ffad04323516400d66

المؤلفون: Lauren Tomlinson, Lauren Hyndman, James W. Firman, Robert Bentley, Jonathan A. Kyffin, Steven D. Webb, Sean McGinty, Parveen Sharma

المصدر: Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)

مصطلحات موضوعية: liver zonation, mathematical modeling, flow system, drug-induced liver injury, in vitro model, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fbioe.2019.00017/full; https://doaj.org/toc/2296-4185

URL الوصول: https://doaj.org/article/e09f9906a319479d8aec40549ac751c6

المؤلفون: Maymona Al-Husari, Steven D. Webb

المصدر: PLoS ONE, Vol 8, Iss 10 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3813778; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/82e705c4063d4820b76035ca3dfe2dc4

المؤلفون: Joseph A Leedale, Baltasar Lucendo-Villarin, Jose Meseguer-Ripolles, Alvile Kasarinaite, Steven D Webb, David C Hay

المصدر: Public Library of Science, PLOS ONE. 16(2):1-16

الإتاحة: https://ideas.repec.org/a/plo/pone00/0244070.html

المؤلفون: Michael P. Storm, Rebecca J. Shipley, Dominic P. Williams, John P. Ward, José Domingo Salazar, Pratibha Mistry, Iain Gardner, Andrew D. Scott, Ian Sorrell, Marianne J. Ellis, Sophie L. Regan, Steven D. Webb

المصدر: Journal of Theoretical Biology. 475:25-33

مصطلحات موضوعية: 0301 basic medicine, Statistics and Probability, RM, Oxygen gradient, Cell Culture Techniques, Drug Evaluation, Preclinical, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Xenobiotics, 03 medical and health sciences, Bioreactors, Oxygen Consumption, 0302 clinical medicine, Bioreactor, Animals, Humans, QA, Acetaminophen, General Immunology and Microbiology, Chemistry, Applied Mathematics, Hollow fibre, General Medicine, Models, Theoretical, QP, Rats, Volumetric flow rate, 030104 developmental biology, Liver, Modeling and Simulation, Hepatocytes, Limiting oxygen concentration, General Agricultural and Biological Sciences, Biological system, Concentration gradient, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::301527e14d31d57efaba7e8008392acc
https://doi.org/10.1016/j.jtbi.2019.05.008

المؤلفون: Joseph Leedale, Fiona Roberts, Craig Murdoch, Simon Walker-Samuel, Rebecca J. Shipley, Hannah West, Paul W. Sweeney, Helen E. Colley, Steven D. Webb

المساهمون: Sweeney, Paul [0000-0003-3385-0696], Leedale, Joseph [0000-0001-9010-4126], Murdoch, Craig [0000-0001-9724-122X], Shipley, Rebecca J. [0000-0002-2818-6228], Apollo - University of Cambridge Repository, Shipley, Rebecca J [0000-0002-2818-6228], Burns, Jorge S.

المصدر: PLoS ONE
PLoS One
PLoS ONE, Vol 16, Iss 7, p e0254208 (2021)
PLOS ONE

مصطلحات موضوعية: 0301 basic medicine, Cancer Treatment, Nanoparticle, Engineering and technology, 0302 clinical medicine, Nanotechnology, QA, Drug Carriers, Multidisciplinary, Cell Death, Pharmaceutics, Endocytosis, Physical sciences, Chemistry, Oncology, Cell Processes, 030220 oncology & carcinogenesis, Drug delivery, Medicine, Chemical Elements, Research Article, Cell Binding, Cell Physiology, Science, FOS: Physical sciences, Geometry, Antineoplastic Agents, Models, Biological, 03 medical and health sciences, Distribution (pharmacology), Animals, Humans, Medicine and health sciences, Biology and life sciences, Cell growth, Spheroid, Cancers and Neoplasms, Biological Transport, Cell Biology, FOS: Engineering and technology, Oxygen, Kinetics, 030104 developmental biology, Radii, Permeability (electromagnetism), Polymersome, Biophysics, Nanoparticles, Drug Delivery, Mathematics

وصف الملف: application/zip; application/pdf; text/xml

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e995e8260976047379fc9cd9e068ae26
https://www.repository.cam.ac.uk/handle/1810/325830

المؤلفون: James W. Dear, Joseph Leedale, Chantelle L. Mason, Nathalie Brillant, Steven D. Webb

المصدر: Computational Toxicology
Leedale, J, Mason, C L, Brillant, N, Webb, S D & Dear, J W 2020, ' Mathematical modelling and statistical analysis of indocyanine green and other biomarkers of hepatic function and drug-induced liver injury ', Computational Toxicology, vol. 16 . https://doi.org/10.1016/j.comtox.2020.100134

مصطلحات موضوعية: Drug, Health, Toxicology and Mutagenesis, media_common.quotation_subject, 010501 environmental sciences, Toxicology, Bioinformatics, 01 natural sciences, Hepatic function, 03 medical and health sciences, chemistry.chemical_compound, Pharmacokinetics, Medicine, Statistical analysis, 030304 developmental biology, 0105 earth and related environmental sciences, media_common, Liver injury, 0303 health sciences, business.industry, medicine.disease, Computer Science Applications, chemistry, Biomarker (medicine), Liver function, business, Indocyanine green

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e5aa59f4203abdef4b42b894095bc0
http://livrepository.liverpool.ac.uk/3099028/1/Manuscript_LEEDALE_Accepted.docx

المؤلفون: Steven D. Webb, Joseph Leedale, David C. Hay, Alvile Kasarinaite, Jose Meseguer-Ripolles, Baltasar Lucendo-Villarin

المصدر: PLoS ONE
PLOS ONE
Leedale, J, Lucendo-Villarin, B, Meseguer Ripolles, J, Kasarinaite, A, Webb, S D & Hay, D C 2021, ' Mathematical modelling of oxygen gradients in stem cell-derived liver tissue ', PLoS ONE, vol. 16, no. 2, e0244070 . https://doi.org/10.1371/journal.pone.0244070
PLoS ONE, Vol 16, Iss 2, p e0244070 (2021)

مصطلحات موضوعية: 0301 basic medicine, Pulmonology, Somatic cell, Cellular differentiation, 02 engineering and technology, Mathematical and Statistical Techniques, Animal Cells, Medicine and Health Sciences, Induced pluripotent stem cell, Multidisciplinary, Simulation and Modeling, Cell Differentiation, 021001 nanoscience & nanotechnology, Cell biology, Chemistry, Liver, Physical Sciences, Medicine, Biological Cultures, Stem cell, Cellular Types, Anatomy, 0210 nano-technology, Research Article, Chemical Elements, Pluripotent Stem Cells, Cell type, Science, Geometry, Biology, Research and Analysis Methods, 03 medical and health sciences, In vivo, Medical Hypoxia, Sine Waves, Humans, Biology and Life Sciences, Cell Biology, Models, Theoretical, Cell Cultures, Oxygen, 030104 developmental biology, Radii, Cell culture, Hepatocytes, Liver function, Mathematical Functions, Mathematics, Developmental Biology

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6467e2b583ea174f591b85d129ab7338
https://pubmed.ncbi.nlm.nih.gov/33556073

المؤلفون: Steven D. Webb, Joseph Leedale, Parveen Sharma, Jonathan A. Kyffin, Dominic P. Williams, Craig Murdoch, Amy L. Harding, Helen E. Colley, R. N. Bearon

المصدر: Interface Focus

مصطلحات موضوعية: drug transport, organoid, Biomedical Engineering, Biophysics, Bioengineering, Biochemistry, Biomaterials, Cell membrane, 03 medical and health sciences, 0302 clinical medicine, In vivo, Organoid, medicine, mathematical modelling, 030304 developmental biology, 0303 health sciences, Chemistry, Spheroid, Articles, In vitro, Pre-clinical development, medicine.anatomical_structure, spheroid, Drug delivery, embryonic structures, hepatocytes, 030217 neurology & neurosurgery, systems pharmacology, Biotechnology, Systems pharmacology, Research Article

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f92349631e0d3042fb8a4c0d14487eaa
http://livrepository.liverpool.ac.uk/3077573/6/rsfs.2019.0041.pdf