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1
المؤلفون: Shaoqing Chen, Paul Gillespie, Sung-Sau So, Steven Gregory Mischke, David Robert Bolin, Nam T. Le, Frank Mennona, Mushtaq Ahmad, Karin Conde-Knape, Charles Burghardt, Hong Wang, Shahid Tannu, Yimin Qian, Jarema Peter Kochan
المصدر: Bioorganic & Medicinal Chemistry Letters. 21:6264-6269
مصطلحات موضوعية: Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing), chemistry.chemical_classification, Ketone, biology, High-throughput screening, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Fructose 6-phosphate, Isoquinolines, Biochemistry, Glutamine, Inhibitory Concentration 50, chemistry.chemical_compound, chemistry, Pharmacokinetics, Enzyme inhibitor, Drug Discovery, biology.protein, Molecular Medicine, Potency, Enzyme Inhibitors, Molecular Biology, Glutamine amidotransferase
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2
المؤلفون: Cheryl Janson, Martin Weisel, Barry Goggin, Liang Weiling, Adrian J. Fretland, Robert Francis Kester, Christine Lukacs, Edmund Lee, Jennifer Lo, J. Heather Hogg, Xiaochun Han, Kyoungja Hong, Stacy Remiszewski, Shirley Li, Ann Polonskaia, John Anthony Moliterni, Kang Le, Lin Gao, Nam T. Le, Christophe Michoud, A. Schutt, Shahid Tannu, Andrew F. Donnell, Shaoqing Chen, Louis J. Lombardo, Steven Gregory Mischke, Mark T. Dvorozniak, Yan Lou, Christine Tardell, Kenneth Carey Rupert, Doug Aguilar, Dave S. Solis
المصدر: Journal of medicinal chemistry. 56(20)
مصطلحات موضوعية: Models, Molecular, Cell Survival, Ubiquitin-Protein Ligases, Blotting, Western, Mice, Nude, Apoptosis, X-Linked Inhibitor of Apoptosis Protein, Inhibitor of apoptosis, Crystallography, X-Ray, Inhibitor of Apoptosis Proteins, Mice, Heterocyclic Compounds, Cell Line, Tumor, Drug Discovery, Animals, Humans, Caspase, Caspase-9, Caspase 7, Benzodiazepinones, Alanine, biology, Molecular Structure, Chemistry, Caspase 3, Xenograft Model Antitumor Assays, In vitro, Cell biology, XIAP, Protein Structure, Tertiary, Models, Chemical, Cell culture, Cancer cell, biology.protein, Molecular Medicine, Female
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3
المؤلفون: Kang Le, Christophe Michoud, Robert T. Taylor, Christine Lukacs, Andrew D. Schutt, Lin Gao, Anthony Specian, Kenneth Carey Rupert, Stacy Remiszewski, Ann Polonskaia, Douglas Aguilar, Barry Goggin, John Anthony Moliterni, J. Heather Hogg, Liang Weiling, Xiaochun Han, Cheryl Janson, Louis J. Lombardo, Martin Weisel, Adrian J. Fretland, Steven Gregory Mischke, Norman Kong, Shirley Li, Robert Francis Kester, Andrew F. Donnell, Kyoungja Hong, Dave S. Solis, Karl Frank, Yan Lou
المصدر: Journal of medicinal chemistry. 56(20)
مصطلحات موضوعية: Models, Molecular, Cell Survival, Ubiquitin-Protein Ligases, Blotting, Western, Regulator, Mice, Nude, Apoptosis, X-Linked Inhibitor of Apoptosis Protein, Inhibitor of apoptosis, Crystallography, X-Ray, Inhibitor of Apoptosis Proteins, Mice, In vivo, Heterocyclic Compounds, Cell Line, Tumor, Drug Discovery, Animals, Humans, Caspase, Caspase 7, Alanine, biology, Molecular Structure, Chemistry, Caspase 3, Antibodies, Monoclonal, Xenograft Model Antitumor Assays, Cell biology, XIAP, Protein Structure, Tertiary, Rats, Oxazepines, Models, Chemical, Cell culture, Cancer cell, biology.protein, Molecular Medicine, Female
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4
المؤلفون: Rebecca Taub, Karin Conde-Knape, Lucy Orzechowski, Warren McComas, Chun Ma, Bruce L. Banner, Fiorenza Falcioni, Steven Gregory Mischke, Irina Hakimi, John P. Tengi, Hong Wang, Robert Francis Kester, Kyungjin Kim, Kshitij Chhabilbhai Thakkar, Francis A. Mennona, Bernard Michael Hennessy, Yimin Qian, Hamid Salari, Steven Joseph Berthel, Jefferson Wright Tilley, Shawn David Erickson
المصدر: Bioorganicmedicinal chemistry letters. 18(4)
مصطلحات موضوعية: Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Crystallography, X-Ray, Biochemistry, Rats, Sprague-Dawley, Structure-Activity Relationship, Piperidines, In vivo, Oral administration, Drug Discovery, Animals, Humans, Selective receptor modulator, Receptors, Somatostatin, Receptor, Molecular Biology, Chemistry, Organic Chemistry, Antagonist, Biological activity, Amides, In vitro, Rats, Kinetics, Indans, Molecular Medicine, Benzimidazoles
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المؤلفون: Steven Joseph Berthel, Ian M. Marks, Xuefeng Yin, Gabriella Pezzoni, Steven Gregory Mischke, Lucja Orzechowski, Franca Sala, Lyubomir T. Vassilev
المصدر: Anti-cancer drugs. 13(4)
مصطلحات موضوعية: Cancer Research, Cell Survival, Pyridines, Cell, Carboxylic Acids, Drug Evaluation, Preclinical, Mice, Nude, Antineoplastic Agents, Apoptosis, Biology, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, medicine, Tumor Cells, Cultured, Animals, Humans, Pharmacology (medical), Cytotoxicity, Mitosis, Pharmacology, Mammary tumor, Cell Cycle, Mammary Neoplasms, Experimental, Cell cycle, medicine.anatomical_structure, Oncology, Biochemistry, Cell culture, Cancer cell, Cancer research, Female, Drug Screening Assays, Antitumor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea801b5bfd5387d61da1d2bda3bb266
https://pubmed.ncbi.nlm.nih.gov/11984081
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