يعرض 1 - 10 نتائج من 34 نتيجة بحث عن '"Steven K. Reilly"', وقت الاستعلام: 1.19s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Functional characterization of T2D-associated SNP effects on baseline and ER stress-responsive β cell transcriptional activation

    المؤلفون: Shubham Khetan, Susan Kales, Romy Kursawe, Alexandria Jillette, Jacob C. Ulirsch, Steven K. Reilly, Duygu Ucar, Ryan Tewhey, Michael L. Stitzel

    المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)

    مصطلحات موضوعية: Science

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/2041-1723

    URL الوصول: https://doaj.org/article/7935194eff76489e8d239c6329e3802f

    Find this article in full text from Springer Verlag. Find this article in full text from ProQuest Full Text Finder
    أضف إلى المفضلة
  2. 2
    دورية أكاديمية
    Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features

    المؤلفون: John P. Ray, Carl G. de Boer, Charles P. Fulco, Caleb A. Lareau, Masahiro Kanai, Jacob C. Ulirsch, Ryan Tewhey, Leif S. Ludwig, Steven K. Reilly, Drew T. Bergman, Jesse M. Engreitz, Robbyn Issner, Hilary K. Finucane, Eric S. Lander, Aviv Regev, Nir Hacohen

    المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

    مصطلحات موضوعية: Science

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/2041-1723

    URL الوصول: https://doaj.org/article/1ebe14a757924ee7b684604e682e0db0

    Find this article in full text from ProQuest Full Text Finder
    أضف إلى المفضلة
  3. 3
    Synthetic DNA spike-ins (SDSIs) enable sample tracking and detection of inter-sample contamination in SARS-CoV-2 sequencing workflows

    المؤلفون: Kim A. Lagerborg, Erica Normandin, Matthew R. Bauer, Gordon Adams, Katherine Figueroa, Christine Loreth, Adrianne Gladden-Young, Bennett M. Shaw, Leah R. Pearlman, Daniel Berenzy, Hannah B. Dewey, Susan Kales, Sabrina T. Dobbins, Erica S. Shenoy, David Hooper, Virginia M. Pierce, Kimon C. Zachary, Daniel J. Park, Bronwyn L. MacInnis, Ryan Tewhey, Jacob E. Lemieux, Pardis C. Sabeti, Steven K. Reilly, Katherine J. Siddle

    المصدر: Nat Microbiol

    مصطلحات موضوعية: Quality Control, Microbiology (medical), Whole Genome Sequencing, SARS-CoV-2, Immunology, COVID-19, Reproducibility of Results, Genome, Viral, Cell Biology, Applied Microbiology and Biotechnology, Microbiology, Article, Workflow, Genetics, Humans, RNA, Viral, Sequence Analysis, DNA Primers

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b53c64fca1bda6ff0f2d9e2e3c672d6
    https://doi.org/10.1038/s41564-021-01019-2

    Find this article in full text from Springer Verlag. Find this article in full text from ProQuest
    أضف إلى المفضلة
  4. 4
    Direct characterization of cis-regulatory elements and functional dissection of complex genetic associations using HCR–FlowFISH

    المؤلفون: Jacob C. Ulirsch, Masahiro Kanai, Alan Gutierrez, Steven K. Reilly, Kousuke Mouri, Daniel Berenzy, Susan Kales, Ryan Tewhey, Ava Mackay-Smith, Pardis C. Sabeti, Redwan M Bhuiyan, Sager J. Gosai, Michael L. Stitzel, Hilary K. Finucane, Adrianne Gladden-Young, Gina M Butler

    المصدر: Nat Genet

    مصطلحات موضوعية: Fatty Acid Desaturases, Quantitative Trait Loci, Locus (genetics), Computational biology, Regulatory Sequences, Nucleic Acid, Biology, Polymorphism, Single Nucleotide, Genome, Article, Delta-5 Fatty Acid Desaturase, Proto-Oncogene Proteins, Genetic variation, Genetics, Deoxyribonuclease I, Humans, CRISPR, Gene silencing, Clustered Regularly Interspaced Short Palindromic Repeats, GATA1 Transcription Factor, Epigenetics, Gene, In Situ Hybridization, Fluorescence, Adaptor Proteins, Signal Transducing, Models, Genetic, Bayes Theorem, LIM Domain Proteins, Flow Cytometry, K562 Cells, Function (biology), RNA, Guide, Kinetoplastida

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40bf57d83bf66d5852c902c570cd6737
    https://doi.org/10.1038/s41588-021-00900-4

    Find this article in full text from Springer Verlag. Find this article in full text from ProQuest
    أضف إلى المفضلة
  5. 5
    Detection of Neanderthal adaptively introgressed genetic variants that modulate reporter gene expression in human immune cells

    المؤلفون: Evelyn Jagoda, Pardis C. Sabeti, Michael Dannemann, James R. Xue, Steven K. Reilly, Fernando Racimo, Sriram Sankararaman, Terence D. Capellini, Emilia Huerta-Sanchez, Luca Pagani, Janet Kelso

    المصدر: Molecular Biology and Evolution
    Jagoda, E, Xue, J R, Reilly, S K, Dannemann, M, Racimo, F, Huerta-Sanchez, E, Sankararaman, S, Kelso, J, Pagani, L, Sabeti, P C & Capellini, T D 2022, ' Detection of Neanderthal Adaptively Introgressed Genetic Variants That Modulate Reporter Gene Expression in Human Immune Cells ', Molecular Biology and Evolution, vol. 39, no. 1, msab304 . https://doi.org/10.1093/molbev/msab304

    مصطلحات موضوعية: SELECTION, introgression, Gene Expression, adaptation, NUCLEAR-FACTOR, KAPPA-B, Biology, AcademicSubjects/SCI01180, SCREEN REVEALS, LINKS, massively parallel reporter assay, 03 medical and health sciences, 0302 clinical medicine, Immune system, positive selection, Gene expression, Genetics, Animals, Humans, TRANSCRIPTION, Allele, Molecular Biology, Transcription factor, Gene, Discoveries, Ecology, Evolution, Behavior and Systematics, Neanderthals, 030304 developmental biology, Inflammation, 0303 health sciences, Reporter gene, Innate immune system, LANDSCAPE, Genome, Human, AcademicSubjects/SCI01130, Genetic Variation, neandertal, Immunity, Innate, GENOME, ADMIXTURE, immune, 030217 neurology & neurosurgery, Function (biology)

    وصف الملف: application/pdf; application/zip

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0665464aba7ddce16a7b54a9687d01
    https://hdl.handle.net/21.11116/0000-0009-E913-B21.11116/0000-0009-E915-921.11116/0000-0009-E916-8

    أضف إلى المفضلة
  6. 6
    Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features

    المؤلفون: Nir Hacohen, Caleb A. Lareau, Drew T. Bergman, Leif S. Ludwig, Masahiro Kanai, Robbyn Issner, John P. Ray, Steven K. Reilly, Eric S. Lander, Jesse M. Engreitz, Carl G. de Boer, Ryan Tewhey, Jacob C. Ulirsch, Charles P. Fulco, Aviv Regev, Hilary K. Finucane

    المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
    Nature Communications

    مصطلحات موضوعية: 0301 basic medicine, Epigenomics, CRISPR-Cas9 genome editing, Linkage disequilibrium, Multifactorial Inheritance, Science, General Physics and Astronomy, Single-nucleotide polymorphism, Locus (genetics), Genomics, Biology, Proof of Concept Study, General Biochemistry, Genetics and Molecular Biology, Article, Linkage Disequilibrium, Autoimmune Diseases, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Genetic variation, Immunogenetics, Humans, Genetic Predisposition to Disease, lcsh:Science, Tumor Necrosis Factor alpha-Induced Protein 3, Genetic association, Genetics, Multidisciplinary, Haplotype, Genetic Variation, Functional genomics, General Chemistry, 030104 developmental biology, Haplotypes, Genetic Loci, Trait, lcsh:Q, 030217 neurology & neurosurgery, Genome-Wide Association Study

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4a8eb964e36a73cb8658af213c1b78
    https://doaj.org/article/1ebe14a757924ee7b684604e682e0db0

    Find this article in full text from ProQuest
    أضف إلى المفضلة
  7. 7
    Evidence of transmission from fully vaccinated individuals in a large outbreak of the SARS-CoV-2 Delta variant in Provincetown, Massachusetts

    المؤلفون: Pardis C. Sabeti, Erika Buzby, Stacey Gabriel, Hanna Shephard, Clare Bernard, Petra L. Schubert, Deirdre Arvidson, Anthony A. Philippakis, Stephanie Baez, Christopher Tomkins-Tinch, Faye L. Reagan, Corey M. Nolet, Matthew Defelice, Catherine M. Brown, Kyle Vernest, Lydia A. Krasilnikova, Gabrielle Gionet, Seana Cofsky, John Beauchamp, Nicholas A. Fitzgerald, Maurice Melchiono, Timelia Fink, Taylor Brock-Fisher, Niall J. Lennon, Jessica Brown, Andrew S. Lang, Bradford P. Taylor, Katelyn S. Messer, Nikolaos Barkas, Sushma Chaluvadi, Selina Clancy, William P. Hanage, Katherine C. DeRuff, Vaira Harik, Bryn Loftness, Gordon Adams, Glen R. Gallagher, Christine Loreth, Brendan Blumenstiel, Lisa M. Anderson, Hillary Johnson, Zoe M. Mandese, Gage K. Moreno, Sabrina T. Dobbins, James Meldrim, Amanda Kearns, Heather M. Rooke, Scott Hennigan, Jacob E. Lemieux, Bronwyn MacInnis, Marissa E. Fisher, Rachel Harrington, Joshua Hall, Maesha A. Ulcena, Sandra Smole, Gina Vicente, Matthew D. Lee, Natasha L. Smith, Sean E. English, Stephen F. Schaffner, Luc Gagne, Michelle Cipicchio, Matthew Doucette, Scott Anderson, Daniel J. Park, Stephanie Ash, Ivan Specht, Lawrence C. Madoff, Steven K. Reilly, Theresa Covell, Katie Larkin, Marianne C. Ray, Sarah D. Slack, Megan E. Vodzak, Jillian Silbert, Johanna Vostok, Beau Schaeffer, Jonna Grimsby, Molly Dunn, Katherine J. Siddle

    المصدر: medRxiv
    article-version (status) pre
    article-version (number) 1

    مصطلحات موضوعية: Delta, Adult, Male, medicine.medical_specialty, Adolescent, Population, Genome, Viral, Disease cluster, Article, law.invention, Disease Outbreaks, Young Adult, law, Epidemiology, medicine, Humans, education, Child, Phylogeny, Aged, Aged, 80 and over, education.field_of_study, Molecular Epidemiology, Whole Genome Sequencing, SARS-CoV-2, Public health, Vaccination, Infant, Newborn, Outbreak, COVID-19, Infant, Middle Aged, Geography, Transmission (mechanics), Massachusetts, Child, Preschool, Female, Contact Tracing, Demography

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77505246cda3c8e1baa2412e143e3659
    https://pubmed.ncbi.nlm.nih.gov/35051367

    أضف إلى المفضلة
  8. 8
    Insights from complex trait fine-mapping across diverse populations

    المؤلفون: Qingbo Wang, Hannah Jacobs, Yukinori Okada, Saori Sakaue, Benjamin M. Neale, Juha Karjalainen, Konrad J. Karczewski, Kaur Alasoo, Nurlan Kerimov, Ryan Tewhey, Yoichiro Kamatani, Pardis C. Sabeti, Koichi Matsuda, Christian Benner, Eric B. Fauman, Masahiro Kanai, FinnGen, François Aguet, Kazuyoshi Ishigaki, Mark J. Daly, Jacob C. Ulirsch, Hilary K. Finucane, Mitja I. Kurki, Aarno Palotie, Kristin G. Ardlie, Steven K. Reilly

    مصطلحات موضوعية: 0303 health sciences, Genome-wide association study, Biology, Biobank, 03 medical and health sciences, 0302 clinical medicine, Evolutionary biology, Trait, Identification (biology), Allele, Allele frequency, Gene, 030217 neurology & neurosurgery, 030304 developmental biology, Genetic association

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e6cc3db92a633682927f660f95867351
    https://doi.org/10.1101/2021.09.03.21262975

    أضف إلى المفضلة
  9. 9
    Functional characterization of T2D-associated SNP effects on baseline and ER stress-responsive β cell transcriptional activation

    المؤلفون: Jacob C. Ulirsch, Duygu Ucar, Ryan Tewhey, Shubham Khetan, Romy Kursawe, Alexandria Jillette, Susan Kales, Michael L. Stitzel, Steven K. Reilly

    المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
    Nature Communications

    مصطلحات موضوعية: Transcriptional Activation, endocrine system, endocrine system diseases, Transcriptional regulatory elements, Science, Quantitative Trait Loci, General Physics and Astronomy, Genome-wide association study, Single-nucleotide polymorphism, Biology, Polymorphism, Single Nucleotide, Article, General Biochemistry, Genetics and Molecular Biology, Cell Line, Mice, Insulin-Secreting Cells, Animals, Humans, SNP, Allele, Alleles, Short Interspersed Nucleotide Elements, Genetic association, Genetics, Multidisciplinary, nutritional and metabolic diseases, Functional genomics, General Chemistry, Endoplasmic Reticulum Stress, Chromatin, Diabetes Mellitus, Type 2, Unfolded protein response, Human genome, Genome-Wide Association Study

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e182b79ea7b75ffa8e28bc599af380c
    https://doi.org/10.1038/s41467-021-25514-6

    Find this article in full text from Springer Verlag. Find this article in full text from ProQuest
    أضف إلى المفضلة
  10. 10
    DNA spike-ins enable confident interpretation of SARS-CoV-2 genomic data from amplicon-based sequencing

    المؤلفون: Katherine Figueroa, Erica S. Shenoy, Daniel J. Park, Kimon C. Zachary, Matthew R. Bauer, Kim A. Lagerborg, Steven K. Reilly, Leah R. Pearlman, David C. Hooper, Katherine J. Siddle, Gordon Adams, Pardis C. Sabeti, Bennett M. Shaw, Bronwyn MacInnis, Jacob E. Lemieux, Adrianne Gladden-Young, Erica Normandin, Virginia M. Pierce, Christine Loreth

    المصدر: bioRxiv
    article-version (status) pre
    article-version (number) 1

    مصطلحات موضوعية: chemistry.chemical_compound, Research groups, Workflow, chemistry, Computer science, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Genomic data, Spike (software development), Computational biology, Amplicon, Viral Sequencing, DNA, Article

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce82f7018937a2a347b3fc6d4705e87
    https://pubmed.ncbi.nlm.nih.gov/33758855

    أضف إلى المفضلة
أدوات البحث: أحصل على تغذية RSS – أرسل هذا البحث بالبريد الإلكتروني – حفظ البحث – جدول التنبيهات: لا شيء