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1دورية أكاديمية
المؤلفون: Shilpi Khare, Steven L Roach, S Whitney Barnes, Dominic Hoepfner, John R Walker, Arnab K Chatterjee, R Jeffrey Neitz, Michelle R Arkin, Case W McNamara, Jaime Ballard, Yin Lai, Yue Fu, Valentina Molteni, Vince Yeh, James H McKerrow, Richard J Glynne, Frantisek Supek
المصدر: PLoS Pathogens, Vol 11, Iss 7, p e1005058 (2015)
مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5
وصف الملف: electronic resource
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المؤلفون: James H. McKerrow, R. Jeffrey Neitz, Jiri Gut, Adam R. Renslo, Michelle R. Arkin, Danielle Kellar, Frantisek Supek, Valentina Molteni, Stephanie A. Robertson, Alejandra Gallardo-Godoy, Steven Chen, Jair L. Siqueira-Neto, Vince Yeh, Richard Glynne, Steven L. Roach, Clifford Bryant, Arnab K. Chatterjee
المصدر: SLAS Discovery. 20:101-111
مصطلحات موضوعية: Chagas disease, medicine.medical_specialty, Latin Americans, Trypanosoma cruzi, Drug Evaluation, Preclinical, Pharmacology, Xanthine, Biochemistry, Cell Line, Analytical Chemistry, Small Molecule Libraries, Mice, Drug Discovery, Animals, Humans, Medicine, Chagas Disease, Intensive care medicine, Selection (genetic algorithm), Cause of death, business.industry, Neglected Diseases, medicine.disease, Cell based assays, Trypanocidal Agents, High-Throughput Screening Assays, Disease Models, Animal, Heart failure, Molecular Medicine, Colorimetry, Identification (biology), business, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe87b7f6b3b7366cba4100e54ca8f43
https://doi.org/10.1177/1087057114553103 -
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المؤلفون: Angela Vassar, Jeffrey N. Miner, Andrew R. Hudson, Mark E. Adams, Steven L. Roach, Dale E. Mais, Zhi Lin, Peter M. Syka, Keith B. Marschke, Robert I. Higuchi
المصدر: Bioorganic & Medicinal Chemistry Letters. 21:1697-1700
مصطلحات موضوعية: Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Enzyme-Linked Immunosorbent Assay, Pharmacology, Biochemistry, Rats, Sprague-Dawley, Structure-Activity Relationship, Receptors, Glucocorticoid, Glucocorticoid receptor, In vivo, Oral administration, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Receptor, Molecular Biology, Drug discovery, Chemistry, Organic Chemistry, Rats, Quinolines, Prednisolone, Molecular Medicine, Glucocorticoid, medicine.drug
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المؤلفون: Jeffrey N. Miner, Deepa Rungta, Lino J. Valdez, Yongkai Li, Andrew Hudson, William W. Lamph, Jean Yen, Dean P. Phillips, and Andrés Negro-Vilar, Lin Zhi, Angie Vassar, Catalina Cuervo, Reid P. Bissonnette, Keith B. Marschke, E. Adam Kallel, Mark E. Adams, Catherine J. Gharbaoui, Robert I. Higuchi, Dale E. Mais, Steven L. Roach
المصدر: Journal of Medicinal Chemistry. 50:4699-4709
مصطلحات موضوعية: Models, Molecular, medicine.medical_specialty, Antineoplastic Agents, Pharmacology, Binding, Competitive, Dexamethasone, Mice, Structure-Activity Relationship, Receptors, Glucocorticoid, Mineralocorticoid receptor, Glucocorticoid receptor, In vivo, Internal medicine, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Benzopyrans, Receptor, Cytotoxicity, Mineralocorticoid Receptor Antagonists, Chemistry, Stereoisomerism, Xenograft Model Antitumor Assays, In vitro, Receptors, Mineralocorticoid, Endocrinology, Quinolines, Molecular Medicine, Multiple Myeloma, medicine.drug
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المؤلفون: Yue Fu, Case W. McNamara, Vince Yeh, Richard Glynne, James H. McKerrow, Arnab K. Chatterjee, John R. Walker, Jaime Ballard, Frantisek Supek, Valentina Molteni, Yin Lai, R. Jeffrey Neitz, Dominic Hoepfner, Steven L. Roach, S. Whitney Barnes, Michelle R. Arkin, Shilpi Khare
المصدر: PLoS Pathogens
PLoS Pathogens, Vol 11, Iss 7, p e1005058 (2015)مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, Antifungal Agents, Cytochrome, Trypanosoma cruzi, Immunology, Respiratory chain, Antimycin A, Microbiology, Electron Transport, chemistry.chemical_compound, Mice, Oxygen Consumption, Virology, Genetics, Animals, Chagas Disease, lcsh:QH301-705.5, Molecular Biology, biology, Myxothiazol, Cytochrome bc1, Drug discovery, Cytochrome b, Cytochrome c, Genomics, Cytochromes b, Molecular biology, 3. Good health, Mitochondria, lcsh:Biology (General), chemistry, Biochemistry, Coenzyme Q – cytochrome c reductase, Mutation, biology.protein, Parasitology, lcsh:RC581-607, Research Article
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المؤلفون: Steven L. Roach, Yan zhi Zhang, Stephanie E. Sen, Sarah M. Smith
المصدر: Tetrahedron Letters. 39:3969-3972
مصطلحات موضوعية: Chemistry, Organic Chemistry, Cationic polymerization, Substrate (chemistry), Polyene, Biochemistry, Chloride, Medicinal chemistry, chemistry.chemical_compound, Yield (chemistry), Drug Discovery, medicine, Anhydrous, Ferric, Organic chemistry, Derivative (chemistry), medicine.drug
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المصدر: Lipids. 32:151-156
مصطلحات موضوعية: Acyclic Monoterpenes, Hamster, Antineoplastic Agents, Pharmacology, Biology, Biochemistry, chemistry.chemical_compound, Geranylgeraniol, Pancreatic tumor, Cricetinae, Pancreatic cancer, Tumor Cells, Cultured, medicine, Animals, Humans, Mesocricetus, Terpenes, Perillyl alcohol, Carcinoma, Organic Chemistry, Cell Biology, Farnesol, medicine.disease, Pancreatic Neoplasms, medicine.anatomical_structure, chemistry, Monoterpenes, lipids (amino acids, peptides, and proteins), Drug Screening Assays, Antitumor, Pancreas, Geraniol
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المؤلفون: Yan zhi Zhang, Stephanie E. Sen, Steven L. Roach
المصدر: The Journal of Organic Chemistry. 61:9534-9537
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Bicyclic molecule, Yield (chemistry), Organic Chemistry, Epoxide, Organic chemistry, Reactivity (chemistry), Lewis acids and bases, Molecular sieve, Polyene, Zeolite
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المؤلفون: Steven L. Roach, Zhi Lin, Robert I. Higuchi, Dale E. Mais, Angie Vassar, Keith B. Marschke, Andrew R. Hudson, Mark E. Adams, Lino J. Valdez, Peter M. Syka, Deepa Rungta
المصدر: Bioorganicmedicinal chemistry letters. 21(6)
مصطلحات موضوعية: medicine.medical_specialty, Carboxy-Lyases, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Transactivation, Enzyme activator, Structure-Activity Relationship, Glucocorticoid receptor, Receptors, Glucocorticoid, Internal medicine, Drug Discovery, medicine, Molecular Biology, Transrepression, Chemistry, Organic Chemistry, Biological activity, Enzyme Activation, Endocrinology, Gluconeogenesis, Quinolines, Molecular Medicine, Phosphoenolpyruvate carboxykinase, Glucocorticoid, medicine.drug
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المؤلفون: Deepa Rungta, Peter M. Syka, Zhi Lin, Andrew R. Hudson, Ryan Lamer, Dale E. Mais, Angie Vassar, Steven L. Roach, Keith B. Marschke, Charlene Hooper, Virginia Heather Sharron Grant, Robert I. Higuchi
المصدر: Bioorganicmedicinal chemistry letters. 21(6)
مصطلحات موضوعية: Carboxy-lyases, Chemistry, Carboxy-Lyases, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Enzyme Activation, Enzyme activator, Transactivation, Glucocorticoid receptor, Receptors, Glucocorticoid, Gluconeogenesis, Drug Discovery, medicine, Quinolines, Molecular Medicine, Phosphoenolpyruvate carboxykinase, Molecular Biology, Glucocorticoid, medicine.drug, Transrepression