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المؤلفون: Anthony Nicholls, Gregory L. Warren, Georgia B. McGaughey, Magali Mathieu, James A. Haigh, Brian P. Kelley, J. Andrew Grant, Robert P. Sheridan, Steven W. Muchmore, Andrew C. Good, Scott P. Brown, Neysa Nevins, Ajay N. Jain
المصدر: Journal of Medicinal Chemistry
مصطلحات موضوعية: Models, Molecular, Library design, Theoretical computer science, Databases, Factual, Protein Conformation, Chemistry, Pharmaceutical, Computation, media_common.quotation_subject, Molecular Conformation, Quantitative Structure-Activity Relationship, Nanotechnology, Biology, Ligands, Adaptability, Software, Compass, Phenomenon, Drug Discovery, Humans, media_common, Virtual screening, Binding Sites, Crystallography, business.industry, Embodied cognition, Drug Design, Perspective, Molecular Medicine, business
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المصدر: Journal of Medicinal Chemistry. 53:4830-4841
مصطلحات موضوعية: Library design, Quantitative structure–activity relationship, Informatics, business.industry, Chemistry, Pharmaceutical, Nanotechnology, Multiple methods, Biology, Data science, Field (computer science), Scientific software, Probability of success, Structure-Activity Relationship, Cheminformatics, Drug Design, Drug Discovery, Humans, Molecular Medicine, business, Algorithms, Pharmaceutical industry
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3
المؤلفون: Steven W. Muchmore, Yvonne C. Martin
المصدر: QSAR & Combinatorial Science. 28:797-801
مصطلحات موضوعية: Quantitative structure–activity relationship, Lead (geology), Chemistry, Computational chemistry, ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS, Organic Chemistry, Drug Discovery, Belief theory, Data mining, Pharmacophore, computer.software_genre, computer, Computer Science Applications
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المؤلفون: Derek A. Debe, Scott P. Brown, Yvonne C. Martin, Steven W. Muchmore, Philip J. Hajduk, James T. Metz
المصدر: Journal of Chemical Information and Modeling. 48:941-948
مصطلحات موضوعية: Virtual screening, General Chemical Engineering, Drug Evaluation, Preclinical, General Chemistry, Chemical similarity, Benchmarking, Library and Information Sciences, computer.software_genre, Computer Science Applications, Interpretation (model theory), Correlation, Pharmaceutical Preparations, Semantic similarity, Similarity (network science), Data mining, Value (mathematics), computer, Algorithms, Probability, Mathematics
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المؤلفون: Steven W. Muchmore, Scott P. Brown
المصدر: Journal of Chemical Information and Modeling. 47:1493-1503
مصطلحات موضوعية: Models, Molecular, Theoretical computer science, Chemistry, Computer science, General Chemical Engineering, Computation, Implicit solvation, Proteins, General Medicine, General Chemistry, Library and Information Sciences, Solver, Ligands, Computer Science Applications, Reduction (complexity), Molecular dynamics, Orders of magnitude (time), Drug Design, Throughput (business), Algorithm, Protein Binding, Protein ligand
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المؤلفون: Steven W. Muchmore, Elizabeth A. Kowaluk, Kennan C. Marsh, Steve McGaraughty, Haixia Yu, Arthur Gomtsyan, Andrew O. Stewart, Shripad S. Bhagwat, Michael F. Jarvis, Karen M. Alexander, Kathy L. Kohlhaas, Clarissa L. Jakob, Chih-Hung Lee, Robin R. Frey, Mark A. Matulenko, Ernest S. Paight, Joseph P. Mikusa, Meiqun Jiang, Stanley Didomenico
المصدر: Bioorganic & Medicinal Chemistry. 15:1586-1605
مصطلحات موضوعية: Protein Conformation, Stereochemistry, Morpholines, Clinical Biochemistry, Pharmaceutical Science, Adenosine kinase, Crystallography, X-Ray, Biochemistry, Rats, Sprague-Dawley, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Animals, Structure–activity relationship, Binding site, Adenosine Kinase, Molecular Biology, Binding Sites, biology, Chemistry, Aryl, Organic Chemistry, Active site, Ligand (biochemistry), Adenosine, Rats, Pyrimidines, biology.protein, Molecular Medicine, Nucleoside, Protein Binding, medicine.drug
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المؤلفون: Scott P. Brown, Brian Kelley, Gregory L. Warren, Steven W. Muchmore
المصدر: Journal of chemical information and modeling. 55(8)
مصطلحات موضوعية: Binding Sites, Computer science, business.industry, Protein Conformation, General Chemical Engineering, Proteins, General Chemistry, Library and Information Sciences, Machine learning, computer.software_genre, Ligands, Computer Science Applications, Molecular Docking Simulation, Catalytic Domain, Drug Design, Pose prediction, Artificial intelligence, business, computer, Strengths and weaknesses, Algorithms
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المؤلفون: Steven W. Muchmore, Scott P. Brown
المصدر: Journal of Chemical Information and Modeling. 46:999-1005
مصطلحات موضوعية: Physics, Theoretical computer science, Computer science, General Chemical Engineering, Computation, Proteins, General Medicine, General Chemistry, Library and Information Sciences, Ligands, computer.software_genre, Grid, Computer Science Applications, Computational science, Grid computing, Drug Design, Poisson Distribution, Adaptation (computer science), Instruction cycle, Protocol (object-oriented programming), computer, Protein Binding, Protein ligand, Binding affinities
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المؤلفون: T. F. Holzman, Uri S. Ladror, Kenneth Jarvis, Hing L. Sham, Mark G. Anderson, Shi-Chung Ng, Le Wang, David Frost, Luis E. Rodriguez, Saul H. Rosenberg, Steven W. Muchmore, John E. Harlan, Jerry Cohen, Debra Ferguson, Yi-Chun Wang, Paul E. Kroeger, Vincent S. Stoll, Gerard M. Sullivan, Ingrid B J K Joseph, Nan-Horng Lin, Wen-Zhen Gu, Haiying Zhang, Clarissa G. Jakob, Kennan C. Marsh, Karl A. Walten
المصدر: Anti-Cancer Drugs. 16:1059-1069
مصطلحات موضوعية: Vascular Endothelial Growth Factor A, Cancer Research, Angiogenesis, Farnesyltransferase, Mice, Nude, Antineoplastic Agents, Crystallography, X-Ray, Mice, chemistry.chemical_compound, Cell Line, Tumor, Neoplasms, Animals, Farnesyltranstransferase, Humans, Potency, Corneal Neovascularization, Pharmacology (medical), Secretion, RNA, Messenger, Enzyme Inhibitors, Cell Proliferation, Pharmacology, Messenger RNA, biology, Farnesyltransferase inhibitor, Imidazoles, Xenograft Model Antitumor Assays, Vascular endothelial growth factor, Oncology, chemistry, ras Proteins, Cancer research, biology.protein, Function (biology)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::857e4ed91e308ba6720a6ef05b9ad4f4
https://doi.org/10.1097/00001813-200511000-00004 -
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المؤلفون: Karin Calles, Steven W. Muchmore, Anna Karin Ramqvist, Mats Carlquist, Jie Yang, Maria Alarcon, Jan Carlstedt-Duke, Owe Engström, John M. Harlan, Jan-Åke Gustafsson, Susanne Thorell, Harri Ahola, Björn Kauppi, Jonathan Greer, Clarissa G. Jakob, Lars Öhman, Mathias Färnegårdh
المصدر: Journal of Biological Chemistry. 278:22748-22754
مصطلحات موضوعية: chemistry.chemical_classification, Stereochemistry, Chemistry, C-terminus, Dimer, Peptide, Cell Biology, Ligand (biochemistry), Biochemistry, chemistry.chemical_compound, Glucocorticoid receptor, Covalent bond, Helix, Coactivator, Molecular Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f444909f0a2cf476ffd1d0faf533bcf3
https://doi.org/10.1074/jbc.m212711200