المؤلفون: Benno Verbelen, Tiziana Girardi, Sergey O. Sulima, Stijn Vereecke, Paulien Verstraete, Jelle Verbeeck, Jonathan Royaert, Sonia Cinque, Lorenzo Montanaro, Marianna Penzo, Maya Imbrechts, Nick Geukens, Thomas Geuens, Koen Dierckx, Daniele Pepe, Kim Kampen, Kim De Keersmaecker

المصدر: Engineering in Life Sciences, Vol 22, Iss 2, Pp 100-114 (2022)

مصطلحات موضوعية: genome engineering, recombinant protein production, ribosomal protein mutation, RPL10, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1618-0240; https://doaj.org/toc/1618-2863

URL الوصول: https://doaj.org/article/73b319b15a6a48d3af486db291b94fc3

المؤلفون: Kim R. Kampen, Laura Fancello, Tiziana Girardi, Gianmarco Rinaldi, Mélanie Planque, Sergey O. Sulima, Fabricio Loayza-Puch, Benno Verbelen, Stijn Vereecke, Jelle Verbeeck, Joyce Op de Beeck, Jonathan Royaert, Pieter Vermeersch, David Cassiman, Jan Cools, Reuven Agami, Mark Fiers, Sarah-Maria Fendt, Kim De Keersmaecker

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/556b5b4b144641dfbb1f4cc05deaa24e

المؤلفون: Kim De Keersmaecker, Karin Thevissen, Bruno P.A. Cammue, Arnout Voet, Sarah-Maria Fendt, David Cassiman, Frederic Rousseau, Joost Schymkowitz, Pieter Vermeersch, Benno Verbelen, Stijn Vereecke, Katrijn De Brucker, Kaat De Cremer, Elien Heylen, Nikolaos Louros, Mélanie Planque, Purvi Gupta, Gianmarco Rinaldi, Kim Rosalie Kampen, Shauni Lien Geeraerts

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578d0ccad576993695e9a350b699f3d0
https://doi.org/10.1158/1535-7163.22521402.v1

المؤلفون: Kim De Keersmaecker, Jonathan D. Dinman, Jelle Verbeeck, Laura Fancello, Daniele Pepe, Stijn Vereecke, Kim R. Kampen, Sergey O. Sulima

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860bdca6120bb1756846a0ac05d4c586
https://doi.org/10.1158/0008-5472.22421078.v1

المؤلفون: Kim De Keersmaecker, Jonathan D. Dinman, Jelle Verbeeck, Laura Fancello, Daniele Pepe, Stijn Vereecke, Kim R. Kampen, Sergey O. Sulima

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7636b929cf411c3bf0ef0e77e7be99b1
https://doi.org/10.1158/0008-5472.c.6510833.v1

المؤلفون: Marie-Françoise O’Donohue, Lydie Da Costa, Marco Lezzerini, Sule Unal, Clément Joret, Marije Bartels, Eva Brilstra, Marijn Scheijde-Vermeulen, Ludivine Wacheul, Kim De Keersmaecker, Stijn Vereecke, Veerle Labarque, Manon Saby, Sophie D. Lefevre, Jessica Platon, Nathalie Montel-Lehry, Nathalie Laugero, Eric Lacazette, Koen van Gassen, Riekelt H. Houtkooper, Pelin Ozlem Simsek-Kiper, Thierry Leblanc, Nese Yarali, Arda Cetinkaya, Nurten A. Akarsu, Pierre-Emmanuel Gleizes, Denis L. J. Lafontaine, Alyson W. MacInnes

المساهمون: Laboratory Medicine, ACS - Diabetes & metabolism, Laboratory Genetic Metabolic Diseases, ACS - Heart failure & arrhythmias, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Laboratory for General Clinical Chemistry

المصدر: Blood, 139(21), 3111-3126. American Society of Hematology
O'Donohue, M-F, da Costa, L, Lezzerini, M, Unal, S, Joret, C, Bartels, M, Brilstra, E, Scheijde-Vermeulen, M, Wacheul, L, de Keersmaecker, K, Vereecke, S, Labarque, V, Saby, M, Lefevre, S D, Platon, J, Montel-Lehry, N, Laugero, N, Lacazette, E, van Gassen, K, Houtkooper, R H, Simsek-Kiper, P O, Leblanc, T, Yarali, N, Cetinkaya, A, Akarsu, N A, Gleizes, P-E, Lafontaine, D L J & MacInnes, A W 2022, ' HEATR3 variants impair nuclear import of uL18 (RPL5) and drive Diamond-Blackfan anemia ', Blood, vol. 139, no. 21, pp. 3111-3126 . https://doi.org/10.1182/blood.2021011846

مصطلحات موضوعية: Ribosomal Proteins, Saccharomyces cerevisiae Proteins, Immunology, Active Transport, Cell Nucleus, Proteins, RNA-Binding Proteins, Saccharomyces cerevisiae, Cell Biology, Hematology, Biochemistry, Mutation, Humans, Tumor Suppressor Protein p53, Ribosomes, Anemia, Diamond-Blackfan

وصف الملف: Print

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd4100cf484e864275fa42206f6a6809
https://research.vumc.nl/en/publications/7731263a-7b25-4244-b994-0a42cb7e6400

المؤلفون: Sarah-Maria Fendt, Elien Heylen, Gianmarco Rinaldi, Karin Thevissen, Kim De Keersmaecker, Bruno P. A. Cammue, Kaat De Cremer, Benno Verbelen, Mélanie Planque, Nikolaos N. Louros, Katrijn De Brucker, Purvi Gupta, Stijn Vereecke, Joost Schymkowitz, Arnout Voet, Kim R. Kampen, Shauni Lien Geeraerts, Frederic Rousseau, David Cassiman, Pieter Vermeersch

المساهمون: Radiotherapie, RS: GROW - R2 - Basic and Translational Cancer Biology, MUMC+: MA Radiotherapie OC (9)

المصدر: Mol Cancer Ther
Molecular Cancer Therapeutics, 20(1), 50-63. American Association for Cancer Research Inc.

مصطلحات موضوعية: 0301 basic medicine, EXPRESSION, Cancer Research, biosynthesis pathway, Breast Neoplasms, Mice, SCID, Pharmacology, MITOCHONDRIAL SERINE HYDROXYMETHYLTRANSFERASE, METABOLISM, Article, Serine, 03 medical and health sciences, 0302 clinical medicine, DEHYDROGENASE, Mice, Inbred NOD, Cell Line, Tumor, Sertraline, Antineoplastic Combined Chemotherapy Protocols, Animals, Humans, Phosphoglycerate dehydrogenase, artemisinins, Phosphoglycerate Dehydrogenase, Cell Proliferation, chemistry.chemical_classification, Glycine Hydroxymethyltransferase, IDENTIFICATION, Thimerosal, Drug Repositioning, ONE-CARBON UNIT, GLYCINE, CANCER, Antidepressive Agents, Molecular Docking Simulation, Drug repositioning, 030104 developmental biology, Enzyme, Oncology, chemistry, Cell culture, Docking (molecular), 030220 oncology & carcinogenesis, Serine hydroxymethyltransferase, Female, Intracellular

وصف الملف: Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bcabcd546838bcc8b91ff193a7d9557
https://cris.maastrichtuniversity.nl/en/publications/f54333ca-86cf-4ff8-aa67-55ae98d57ef8

المؤلفون: Sergey O. Sulima, David Cassiman, Reuven Agami, Benno Verbelen, Jan Cools, Jonathan Royaert, Mélanie Planque, Sarah-Maria Fendt, Joyce Op de Beeck, Pieter Vermeersch, Tiziana Girardi, Kim De Keersmaecker, Mark Fiers, Stijn Vereecke, Gianmarco Rinaldi, Jelle Verbeeck, Laura Fancello, Fabricio Loayza-Puch, Kim R. Kampen

المساهمون: Molecular Genetics

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications, 10:2542. Nature Publishing Group
Nature Communications

مصطلحات موضوعية: Ribosomal Proteins, 0301 basic medicine, Ribosomal Protein L10, Science, Glycine, General Physics and Astronomy, 02 engineering and technology, Biology, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Ribosome, Article, General Biochemistry, Genetics and Molecular Biology, Cell Line, Serine, Mice, 03 medical and health sciences, Ribosomal protein, Transcription (biology), hemic and lymphatic diseases, Protein biosynthesis, Animals, RNA, Messenger, lcsh:Science, Gene, Multidisciplinary, Molecular medicine, Sequence Analysis, RNA, Gene Expression Profiling, Phosphoserine phosphatase, General Chemistry, 021001 nanoscience & nanotechnology, Cancer metabolism, Phosphoric Monoester Hydrolases, 3. Good health, Cell biology, Mechanisms of disease, 030104 developmental biology, MRNA Sequencing, Polyribosomes, Protein Biosynthesis, Mutation, lcsh:Q, Gene expression, 0210 nano-technology, Ribosomes

وصف الملف: application/pdf; Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494833e9acbd6b508c5b079e99efe336
http://link.springer.com/article/10.1038/s41467-019-10508-2

المؤلفون: Jan Cools, Pieter Vermeersch, Anne Uyttebroeck, Benno Verbelen, Anthony V. Moorman, Gianmarco Rinaldi, Pieter Spincemaille, Sarah-Maria Fendt, Jules P.P. Meijerink, Tiziana Girardi, Joyce Op de Beeck, David Cassiman, Stijn Vereecke, Laura Fancello, Sergey O. Sulima, Kim R. Kampen, Christine J. Harrison, Kim De Keersmaecker, Jelle Verbeeck

المصدر: Leukemia

مصطلحات موضوعية: 0301 basic medicine, Male, Ribosomal Proteins, Cancer Research, Ribosomal Protein L10, Statement (logic), Sequencing data, Biology, Internal Ribosome Entry Sites, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, 03 medical and health sciences, Mice, 0302 clinical medicine, Mice, Inbred NOD, Tumor Cells, Cultured, Animals, Humans, Phosphorylation, Protein Kinase Inhibitors, Genetics, Gene Expression Regulation, Leukemic, Published Erratum, RNA, Correction, Translation (biology), Hematology, Ribosomal RNA, Xenograft Model Antitumor Assays, Internal ribosome entry site, Oxidative Stress, 030104 developmental biology, Oncology, Proto-Oncogene Proteins c-bcl-2, 030220 oncology & carcinogenesis, Protein Biosynthesis, Mutation (genetic algorithm), Mutation, Ribosomes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3612f244a1a0895a418c107ff4f0bf4
http://europepmc.org/articles/PMC6756081

المؤلفون: Mélanie Planque, Sarah-Maria Fendt, Katrijn De Brucker, Arnout Voet, Shauni Lien Geeraerts, Bruno P. A. Cammue, Stijn Vereecke, Karin Thevissen, Purvi Gupta, Kim R. Kampen, Benno Verbelen, Gianmarco Rinaldi, Kim De Keersmaecker, David Cassiman, Kaat De Cremer, Pieter Vermeersch

مصطلحات موضوعية: Serine, chemistry.chemical_classification, Drug repositioning, Enzyme, Cell cycle checkpoint, chemistry, Cell culture, Serine hydroxymethyltransferase, Phosphoglycerate dehydrogenase, Pharmacology, Intracellular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::555d8d11beec0d4d6df6f63f3da309ba
https://doi.org/10.1101/2020.06.12.148395