المؤلفون: Torres-Terán I; University of Greifswald. Department of Pharmacy, Institute of Biopharmaceutics and Pharmaceutical Technology, Center of Drug Absorption and Transport, 3 Felix Hausdorff Street, 17489 Greifswald, Germany; Sanofi-Aventis Deutschland GmbH, R&D, Global CMC Development, Synthetics Platform. Industriepark Hoechst, H770, D-65926 Frankfurt am Main, Germany., Venczel M; University of Greifswald. Department of Pharmacy, Institute of Biopharmaceutics and Pharmaceutical Technology, Center of Drug Absorption and Transport, 3 Felix Hausdorff Street, 17489 Greifswald, Germany., Klein S; Sanofi-Aventis Deutschland GmbH, R&D, Global CMC Development, Synthetics Platform. Industriepark Hoechst, H770, D-65926 Frankfurt am Main, Germany. Electronic address: sandra.klein@uni-greifswald.de.

المصدر: International journal of pharmaceutics [Int J Pharm] 2024 Jun 10; Vol. 658, pp. 124227. Date of Electronic Publication: 2024 May 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Extracellular Fluid*/metabolism, Animals ; Humans ; Mice ; Rats ; Injections, Subcutaneous ; Subcutaneous Absorption ; Models, Biological ; Drug Liberation

المؤلفون: Lou H; Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS, 66047, USA. lou0@ku.edu.; Biopharmaceutical Innovation and Optimization Center, University of Kansas, Lawrence, KS, 66047, USA. lou0@ku.edu., Hageman MJ; Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS, 66047, USA. mhageman@ku.edu.; Biopharmaceutical Innovation and Optimization Center, University of Kansas, Lawrence, KS, 66047, USA. mhageman@ku.edu.

المصدر: The AAPS journal [AAPS J] 2023 Mar 22; Vol. 25 (3), pp. 29. Date of Electronic Publication: 2023 Mar 22.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Association of Pharmaceutical Scientists Country of Publication: United States NLM ID: 101223209 Publication Model: Electronic Cited Medium: Internet ISSN: 1550-7416 (Electronic) Linking ISSN: 15507416 NLM ISO Abbreviation: AAPS J Subsets: MEDLINE

مواضيع طبية MeSH: Subcutaneous Absorption*, Drug Liberation ; Solubility ; Suspensions ; Particle Size

المؤلفون: Bei R; Lilly Research Laboratories, Lilly Corporate Center, Eli Lilly and Company, Indianapolis, IN, USA., Thomas J; Lilly Research Laboratories, Lilly Corporate Center, Eli Lilly and Company, Indianapolis, IN, USA., Kapur S; Lilly Research Laboratories, Lilly Corporate Center, Eli Lilly and Company, Indianapolis, IN, USA., Woldeyes M; Lilly Research Laboratories, Lilly Corporate Center, Eli Lilly and Company, Indianapolis, IN, USA., Rauk A; Lilly Research Laboratories, Lilly Corporate Center, Eli Lilly and Company, Indianapolis, IN, USA., Robarge J; Lilly Research Laboratories, Lilly Corporate Center, Eli Lilly and Company, Indianapolis, IN, USA., Feng J; Lilly Research Laboratories, Lilly Corporate Center, Eli Lilly and Company, Indianapolis, IN, USA., Abbou Oucherif K; Lilly Research Laboratories, Lilly Corporate Center, Eli Lilly and Company, Indianapolis, IN, USA.

المصدر: MAbs [MAbs] 2024 Jan-Dec; Vol. 16 (1), pp. 2352887. Date of Electronic Publication: 2024 May 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101479829 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-0870 (Electronic) Linking ISSN: 19420862 NLM ISO Abbreviation: MAbs Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Monoclonal*/pharmacokinetics , Machine Learning*, Humans ; Injections, Subcutaneous ; Subcutaneous Absorption ; Models, Biological

المؤلفون: Zheng F; Industrial & Physical Pharmacy, Purdue University West Lafayette, Indiana, USA., Hou P; Industrial & Physical Pharmacy, Purdue University West Lafayette, Indiana, USA., Corpstein CD; Industrial & Physical Pharmacy, Purdue University West Lafayette, Indiana, USA., Park K; Industrial & Physical Pharmacy, Purdue University West Lafayette, Indiana, USA., Li T; Industrial & Physical Pharmacy, Purdue University West Lafayette, Indiana, USA. Electronic address: tonglei@purdue.edu.

المصدر: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2021 Sep 10; Vol. 337, pp. 407-416. Date of Electronic Publication: 2021 Jul 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Monoclonal* , Subcutaneous Absorption*, Computer Simulation ; Humans ; Injections, Subcutaneous ; Kinetics ; Models, Biological

المؤلفون: Faggionato E, Schiavon M, Man CD

المصدر: Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference [Annu Int Conf IEEE Eng Med Biol Soc] 2021 Nov; Vol. 2021, pp. 4226-4229.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: [IEEE] Country of Publication: United States NLM ID: 101763872 Publication Model: Print Cited Medium: Internet ISSN: 2694-0604 (Electronic) Linking ISSN: 23757477 NLM ISO Abbreviation: Annu Int Conf IEEE Eng Med Biol Soc Subsets: MEDLINE

مواضيع طبية MeSH: Insulin, Long-Acting* , Subcutaneous Absorption*, Humans ; Hypoglycemic Agents ; Insulin/metabolism ; Insulin Glargine

المؤلفون: D'Haens G; From the Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam (G.D.); Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York (M.D., B.E.S.); the Center for Advanced IBD Research and Treatment, Kitasato University, Kitasato Institute Hospital, Tokyo (T.K.); Guy's Hospital, St. Thomas' Hospital, and the School of Immunology and Microbial Sciences, King's College London - all in London (P.M.I.); Research Institute for IBD-HaFCED, Hamburg, Germany (S.H.); Riga Stradins University, Riga, Latvia (J.P.); Eli Lilly, Indianapolis (K.K., J.L., X.L., T.L., J.M., N.M., V.A., C.M.); and the University of California San Diego, La Jolla (W.S.)., Dubinsky M; From the Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam (G.D.); Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York (M.D., B.E.S.); the Center for Advanced IBD Research and Treatment, Kitasato University, Kitasato Institute Hospital, Tokyo (T.K.); Guy's Hospital, St. Thomas' Hospital, and the School of Immunology and Microbial Sciences, King's College London - all in London (P.M.I.); Research Institute for IBD-HaFCED, Hamburg, Germany (S.H.); Riga Stradins University, Riga, Latvia (J.P.); Eli Lilly, Indianapolis (K.K., J.L., X.L., T.L., J.M., N.M., V.A., C.M.); and the University of California San Diego, La Jolla (W.S.)., Kobayashi T; From the Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam (G.D.); Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York (M.D., B.E.S.); the Center for Advanced IBD Research and Treatment, Kitasato University, Kitasato Institute Hospital, Tokyo (T.K.); Guy's Hospital, St. Thomas' Hospital, and the School of Immunology and Microbial Sciences, King's College London - all in London (P.M.I.); Research Institute for IBD-HaFCED, Hamburg, Germany (S.H.); Riga Stradins University, Riga, Latvia (J.P.); Eli Lilly, Indianapolis (K.K., J.L., X.L., T.L., J.M., N.M., V.A., C.M.); and the University of California San Diego, La Jolla (W.S.)., Irving PM; From the Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam (G.D.); Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York (M.D., B.E.S.); the Center for Advanced IBD Research and Treatment, Kitasato University, Kitasato Institute Hospital, Tokyo (T.K.); Guy's Hospital, St. Thomas' Hospital, and the School of Immunology and Microbial Sciences, King's College London - all in London (P.M.I.); Research Institute for IBD-HaFCED, Hamburg, Germany (S.H.); Riga Stradins University, Riga, Latvia (J.P.); Eli Lilly, Indianapolis (K.K., J.L., X.L., T.L., J.M., N.M., V.A., C.M.); and the University of California San Diego, La Jolla (W.S.)., Howaldt S; From the Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam (G.D.); Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York (M.D., B.E.S.); the Center for Advanced IBD Research and Treatment, Kitasato University, Kitasato Institute Hospital, Tokyo (T.K.); Guy's Hospital, St. Thomas' Hospital, and the School of Immunology and Microbial Sciences, King's College London - all in London (P.M.I.); Research Institute for IBD-HaFCED, Hamburg, Germany (S.H.); Riga Stradins University, Riga, Latvia (J.P.); Eli Lilly, Indianapolis (K.K., J.L., X.L., T.L., J.M., N.M., V.A., C.M.); and the University of California San Diego, La Jolla (W.S.)., Pokrotnieks J; From the Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam (G.D.); Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York (M.D., B.E.S.); the Center for Advanced IBD Research and Treatment, Kitasato University, Kitasato Institute Hospital, Tokyo (T.K.); Guy's Hospital, St. Thomas' Hospital, and the School of Immunology and Microbial Sciences, King's College London - all in London (P.M.I.); Research Institute for IBD-HaFCED, Hamburg, Germany (S.H.); Riga Stradins University, Riga, Latvia (J.P.); Eli Lilly, Indianapolis (K.K., J.L., X.L., T.L., J.M., N.M., V.A., C.M.); and the University of California San Diego, La Jolla (W.S.)., Krueger K; From the Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam (G.D.); Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York (M.D., B.E.S.); the Center for Advanced IBD Research and Treatment, Kitasato University, Kitasato Institute Hospital, Tokyo (T.K.); Guy's Hospital, St. Thomas' Hospital, and the School of Immunology and Microbial Sciences, King's College London - all in London (P.M.I.); Research Institute for IBD-HaFCED, Hamburg, Germany (S.H.); Riga Stradins University, Riga, Latvia (J.P.); Eli Lilly, Indianapolis (K.K., J.L., X.L., T.L., J.M., N.M., V.A., C.M.); and the University of California San Diego, La Jolla (W.S.)., Laskowski J; From the Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam (G.D.); Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York (M.D., B.E.S.); the Center for Advanced IBD Research and Treatment, Kitasato University, Kitasato Institute Hospital, Tokyo (T.K.); Guy's Hospital, St. Thomas' Hospital, and the School of Immunology and Microbial Sciences, King's College London - all in London (P.M.I.); Research Institute for IBD-HaFCED, Hamburg, Germany (S.H.); Riga Stradins University, Riga, Latvia (J.P.); Eli Lilly, Indianapolis (K.K., J.L., X.L., T.L., J.M., N.M., V.A., C.M.); and the University of California San Diego, La Jolla (W.S.)., Li X; From the Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam (G.D.); Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York (M.D., B.E.S.); the Center for Advanced IBD Research and Treatment, Kitasato University, Kitasato Institute Hospital, Tokyo (T.K.); Guy's Hospital, St. Thomas' Hospital, and the School of Immunology and Microbial Sciences, King's College London - all in London (P.M.I.); Research Institute for IBD-HaFCED, Hamburg, Germany (S.H.); Riga Stradins University, Riga, Latvia (J.P.); Eli Lilly, Indianapolis (K.K., J.L., X.L., T.L., J.M., N.M., V.A., C.M.); and the University of California San Diego, La Jolla (W.S.)., Lissoos T; From the Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam (G.D.); Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York (M.D., B.E.S.); the Center for Advanced IBD Research and Treatment, Kitasato University, Kitasato Institute Hospital, Tokyo (T.K.); Guy's Hospital, St. Thomas' Hospital, and the School of Immunology and Microbial Sciences, King's College London - all in London (P.M.I.); Research Institute for IBD-HaFCED, Hamburg, Germany (S.H.); Riga Stradins University, Riga, Latvia (J.P.); Eli Lilly, Indianapolis (K.K., J.L., X.L., T.L., J.M., N.M., V.A., C.M.); and the University of California San Diego, La Jolla (W.S.)., Milata J; From the Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam (G.D.); Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York (M.D., B.E.S.); the Center for Advanced IBD Research and Treatment, Kitasato University, Kitasato Institute Hospital, Tokyo (T.K.); Guy's Hospital, St. Thomas' Hospital, and the School of Immunology and Microbial Sciences, King's College London - all in London (P.M.I.); Research Institute for IBD-HaFCED, Hamburg, Germany (S.H.); Riga Stradins University, Riga, Latvia (J.P.); Eli Lilly, Indianapolis (K.K., J.L., X.L., T.L., J.M., N.M., V.A., C.M.); and the University of California San Diego, La Jolla (W.S.)., Morris N; From the Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam (G.D.); Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York (M.D., B.E.S.); the Center for Advanced IBD Research and Treatment, Kitasato University, Kitasato Institute Hospital, Tokyo (T.K.); Guy's Hospital, St. Thomas' Hospital, and the School of Immunology and Microbial Sciences, King's College London - all in London (P.M.I.); Research Institute for IBD-HaFCED, Hamburg, Germany (S.H.); Riga Stradins University, Riga, Latvia (J.P.); Eli Lilly, Indianapolis (K.K., J.L., X.L., T.L., J.M., N.M., V.A., C.M.); and the University of California San Diego, La Jolla (W.S.)., Arora V; From the Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam (G.D.); Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York (M.D., B.E.S.); the Center for Advanced IBD Research and Treatment, Kitasato University, Kitasato Institute Hospital, Tokyo (T.K.); Guy's Hospital, St. Thomas' Hospital, and the School of Immunology and Microbial Sciences, King's College London - all in London (P.M.I.); Research Institute for IBD-HaFCED, Hamburg, Germany (S.H.); Riga Stradins University, Riga, Latvia (J.P.); Eli Lilly, Indianapolis (K.K., J.L., X.L., T.L., J.M., N.M., V.A., C.M.); and the University of California San Diego, La Jolla (W.S.)., Milch C; From the Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam (G.D.); Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York (M.D., B.E.S.); the Center for Advanced IBD Research and Treatment, Kitasato University, Kitasato Institute Hospital, Tokyo (T.K.); Guy's Hospital, St. Thomas' Hospital, and the School of Immunology and Microbial Sciences, King's College London - all in London (P.M.I.); Research Institute for IBD-HaFCED, Hamburg, Germany (S.H.); Riga Stradins University, Riga, Latvia (J.P.); Eli Lilly, Indianapolis (K.K., J.L., X.L., T.L., J.M., N.M., V.A., C.M.); and the University of California San Diego, La Jolla (W.S.)., Sandborn W; From the Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam (G.D.); Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York (M.D., B.E.S.); the Center for Advanced IBD Research and Treatment, Kitasato University, Kitasato Institute Hospital, Tokyo (T.K.); Guy's Hospital, St. Thomas' Hospital, and the School of Immunology and Microbial Sciences, King's College London - all in London (P.M.I.); Research Institute for IBD-HaFCED, Hamburg, Germany (S.H.); Riga Stradins University, Riga, Latvia (J.P.); Eli Lilly, Indianapolis (K.K., J.L., X.L., T.L., J.M., N.M., V.A., C.M.); and the University of California San Diego, La Jolla (W.S.)., Sands BE; From the Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam (G.D.); Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York (M.D., B.E.S.); the Center for Advanced IBD Research and Treatment, Kitasato University, Kitasato Institute Hospital, Tokyo (T.K.); Guy's Hospital, St. Thomas' Hospital, and the School of Immunology and Microbial Sciences, King's College London - all in London (P.M.I.); Research Institute for IBD-HaFCED, Hamburg, Germany (S.H.); Riga Stradins University, Riga, Latvia (J.P.); Eli Lilly, Indianapolis (K.K., J.L., X.L., T.L., J.M., N.M., V.A., C.M.); and the University of California San Diego, La Jolla (W.S.).

مؤلفون مشاركون: LUCENT Study Group

المصدر: The New England journal of medicine [N Engl J Med] 2023 Jun 29; Vol. 388 (26), pp. 2444-2455.

نوع المنشور: Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial

بيانات الدورية: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE

مواضيع طبية MeSH: Colitis, Ulcerative*/drug therapy , Anti-Inflammatory Agents, Non-Steroidal*/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal*/adverse effects , Anti-Inflammatory Agents, Non-Steroidal*/immunology , Anti-Inflammatory Agents, Non-Steroidal*/therapeutic use, Adult ; Humans ; Double-Blind Method ; Herpes Zoster/chemically induced ; Herpes Zoster/etiology ; Induction Chemotherapy/adverse effects ; Induction Chemotherapy/methods ; Maintenance Chemotherapy/adverse effects ; Maintenance Chemotherapy/methods ; Opportunistic Infections/chemically induced ; Opportunistic Infections/etiology ; Remission Induction ; Administration, Intravenous ; Subcutaneous Absorption

المؤلفون: Fujiwara Y; Laboratory of Animal Radiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan., Nakamura T; Laboratory of Animal Radiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan., Maehara T; Laboratory of Animal Radiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan., Hayashi A; Laboratory of Animal Radiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan., Aritake K; Laboratory of Chemical Pharmacology, Daiichi University of Pharmacy, Fukuoka 815-8511, Japan., Murata T; Laboratory of Animal Radiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 May 30; Vol. 120 (22), pp. e2300284120. Date of Electronic Publication: 2023 May 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Prostaglandins* , Bee Venoms*, Animals ; Mice ; Mast Cells/metabolism ; Prostaglandin D2/metabolism ; Subcutaneous Absorption ; Intramolecular Oxidoreductases/metabolism ; Allergens

المؤلفون: Torres-Terán I; University of Greifswald, Department of Pharmacy, Institute of Biopharmaceutics and Pharmaceutical Technology, Center of Drug Absorption and Transport, Felix-Hausdorff-Strasse 3, 17489 Greifswald, Germany; Sanofi-Aventis Deutschland GmbH, R&D, Global CMC Development, Synthetics Platform, Industriepark Hoechst, 65926 Frankfurt am Main, Germany., Venczel M; Sanofi-Aventis Deutschland GmbH, R&D, Global CMC Development, Synthetics Platform, Industriepark Hoechst, 65926 Frankfurt am Main, Germany., Stieler T; Sanofi-Aventis Deutschland GmbH, R&D, Global CMC Development, Synthetics Platform, Industriepark Hoechst, 65926 Frankfurt am Main, Germany., Parisi L; Eurofins Lancaster Laboratories Professional Scientific Services, 2425 New Holland Pike, Lancaster, PA 17601, USA., Kloss A; Sanofi, R&D, Global CMC Development, Synthetics Platform, 350 Water Street, Cambridge, MA 02141, USA., Klein S; University of Greifswald, Department of Pharmacy, Institute of Biopharmaceutics and Pharmaceutical Technology, Center of Drug Absorption and Transport, Felix-Hausdorff-Strasse 3, 17489 Greifswald, Germany.

المصدر: International journal of pharmaceutics [Int J Pharm] 2023 May 10; Vol. 638, pp. 122906. Date of Electronic Publication: 2023 Mar 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Extracellular Fluid* , Subcutaneous Tissue*, Rats ; Mice ; Animals ; Swine ; Swine, Miniature ; Subcutaneous Absorption

المؤلفون: Spitters TWGM; Laboratoire de bio-ingénierie et de biophysique de l'Université de Sherbrooke, Department of Chemical and Biotechnological Engineering, Université de Sherbrooke, Sherbrooke, Canada.; Pharmacology Institute of Sherbrooke, Faculté de Médecine et des Sciences de la Santé, Sherbrooke, Canada., Andersen PL; Laboratoire de bio-ingénierie et de biophysique de l'Université de Sherbrooke, Department of Chemical and Biotechnological Engineering, Université de Sherbrooke, Sherbrooke, Canada.; Pharmacology Institute of Sherbrooke, Faculté de Médecine et des Sciences de la Santé, Sherbrooke, Canada., Martel C; Laboratoire de bio-ingénierie et de biophysique de l'Université de Sherbrooke, Department of Chemical and Biotechnological Engineering, Université de Sherbrooke, Sherbrooke, Canada.; Pharmacology Institute of Sherbrooke, Faculté de Médecine et des Sciences de la Santé, Sherbrooke, Canada., Vermette P; Laboratoire de bio-ingénierie et de biophysique de l'Université de Sherbrooke, Department of Chemical and Biotechnological Engineering, Université de Sherbrooke, Sherbrooke, Canada.; Pharmacology Institute of Sherbrooke, Faculté de Médecine et des Sciences de la Santé, Sherbrooke, Canada.

المصدر: Assay and drug development technologies [Assay Drug Dev Technol] 2018 Dec; Vol. 16 (8), pp. 462-471. Date of Electronic Publication: 2018 Aug 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101151468 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-8127 (Electronic) Linking ISSN: 1540658X NLM ISO Abbreviation: Assay Drug Dev Technol Subsets: MEDLINE

مواضيع طبية MeSH: Models, Animal*, Alginates/*metabolism , Drug Carriers/*metabolism , Pancreas/*metabolism , Subcutaneous Absorption/*physiology , Tissue Distribution/*physiology, Alginates/administration & dosage ; Animals ; Drug Carriers/administration & dosage ; Drug Evaluation, Preclinical/methods ; Female ; Pancreas/drug effects ; Rats ; Rats, Sprague-Dawley ; Subcutaneous Absorption/drug effects ; Tissue Distribution/drug effects

المؤلفون: Uusalo P; Department of Anaesthesiology and Intensive Care, University of Turku, P.O. Box 51, (Kiinamyllynkatu 4-8), 20521, Turku, Finland. pijuus@utu.fi.; Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, Turku, Finland. pijuus@utu.fi., Al-Ramahi D; Institute of Biomedicine, University of Turku, and Unit of Clinical Pharmacology, Turku University Hospital, Turku, Finland., Tilli I; Department of Anaesthesiology and Intensive Care, University of Turku, P.O. Box 51, (Kiinamyllynkatu 4-8), 20521, Turku, Finland., Aantaa RA; Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, Turku, Finland., Scheinin M; Institute of Biomedicine, University of Turku, and Unit of Clinical Pharmacology, Turku University Hospital, Turku, Finland., Saari TI; Department of Anaesthesiology and Intensive Care, University of Turku, P.O. Box 51, (Kiinamyllynkatu 4-8), 20521, Turku, Finland.; Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, Turku, Finland.

المصدر: European journal of clinical pharmacology [Eur J Clin Pharmacol] 2018 Aug; Vol. 74 (8), pp. 1047-1054. Date of Electronic Publication: 2018 Apr 17.

نوع المنشور: Journal Article; Randomized Controlled Trial

بيانات الدورية: Publisher: Springer Country of Publication: Germany NLM ID: 1256165 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1041 (Electronic) Linking ISSN: 00316970 NLM ISO Abbreviation: Eur J Clin Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Subcutaneous Absorption*/drug effects, Dexmedetomidine/*pharmacokinetics , Dexmedetomidine/*pharmacology , Hemodynamics/*drug effects, Administration, Intravenous ; Biological Availability ; Catecholamines/blood ; Cross-Over Studies ; Dexmedetomidine/administration & dosage ; Dexmedetomidine/blood ; Healthy Volunteers ; Humans ; Hypnotics and Sedatives/pharmacology ; Injections, Subcutaneous ; Male ; Young Adult