المؤلفون: Robert D. Morgan, George J. Burghel, Helene Schlecht, Andrew R. Clamp, Jurjees Hasan, Claire L. Mitchell, Zena Salih, Joseph Shaw, Sudha Desai, Gordon C. Jayson, Emma R. Woodward, D. Gareth R. Evans

المصدر: Cancers, Vol 16, Iss 1, p 177 (2023)

مصطلحات موضوعية: ovarian cancer, germline, somatic, BRCA1, BRCA2, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2072-6694/16/1/177; https://doaj.org/toc/2072-6694

URL الوصول: https://doaj.org/article/3122f59188784a6ab441ba4e0329ec9f

المؤلفون: Camilla Coulson-Gilmer, Robert D. Morgan, Louisa Nelson, Bethany M. Barnes, Anthony Tighe, René Wardenaar, Diana C. J. Spierings, Helene Schlecht, George J. Burghel, Floris Foijer, Sudha Desai, Joanne C. McGrail, Stephen S. Taylor

المصدر: Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-26 (2021)

مصطلحات موضوعية: High-grade serous ovarian cancer, PARG inhibitor, DNA replication, Replication stress, Gene expression signature, Predictive biomarkers, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1756-9966

URL الوصول: https://doaj.org/article/f3fbd598ccd148c7a8595d1081bbfe91

المؤلفون: Bethany M. Barnes, Louisa Nelson, Anthony Tighe, George J. Burghel, I-Hsuan Lin, Sudha Desai, Joanne C. McGrail, Robert D. Morgan, Stephen S. Taylor

المصدر: Genome Medicine, Vol 13, Iss 1, Pp 1-19 (2021)

مصطلحات موضوعية: Ovarian cancer, Non-negative matrix factorization, RNA sequencing, Subtype classification, Machine learning, Transcriptomics, Medicine, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1756-994X

URL الوصول: https://doaj.org/article/b2e1e2d43ff14480be8e2212ca3fea6d

المؤلفون: Louisa Nelson, Anthony Tighe, Anya Golder, Samantha Littler, Bjorn Bakker, Daniela Moralli, Syed Murtuza Baker, Ian J. Donaldson, Diana C. J. Spierings, René Wardenaar, Bethanie Neale, George J. Burghel, Brett Winter-Roach, Richard Edmondson, Andrew R. Clamp, Gordon C. Jayson, Sudha Desai, Catherine M. Green, Andy Hayes, Floris Foijer, Robert D. Morgan, Stephen S. Taylor

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/5f96b03935524c6e8d18bbc5878047b4

المؤلفون: Nuruddeen D Lewis, Lori A Patnaude, Josephine Pelletier, Donald J Souza, Susan M Lukas, F James King, Jonathan D Hill, Dimitria E Stefanopoulos, Kelli Ryan, Sudha Desai, Donna Skow, Stefan G Kauschke, Andre Broermann, Daniel Kuzmich, Christian Harcken, Eugene R Hickey, Louise K Modis

المصدر: PLoS ONE, Vol 9, Iss 6, p e100883 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4072711?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/26efe3ddb1914034965ffa796c1b72fb

المؤلفون: Robert D Morgan, George J Burghel, Nicola Flaum, Michael Bulman, Philip Smith, Andrew R Clamp, Jurjees Hasan, Claire Mitchell, Zena Salih, Emma R Woodward, Fiona Lalloo, Joseph Shaw, Sudha Desai, Emma J Crosbie, Richard J Edmondson, Helene Schlecht, Andrew J Wallace, Gordon C Jayson, D Gareth R Evans

المصدر: Morgan, R D, Burghel, G J, Flaum, N, Bulman, M, Smith, P, Clamp, A R, Hasan, J, Mitchell, C, Salih, Z, Woodward, E R, Lalloo, F, Shaw, J, Desai, S, Crosbie, E J, Edmondson, R J, Schlecht, H, Wallace, A J, Jayson, G C & Evans, D G R 2022, ' Predicting the likelihood of a BRCA1/2 pathogenic variant being somatic by testing only tumour DNA in non-mucinous high-grade epithelial ovarian cancer ', Journal Of Clinical Pathology . https://doi.org/10.1136/jcp-2022-208369
Burghel, GJ, Flaum, N, Bulman, M, Clamp, AR, Hasan, J, Salih, Z, Lalloo, F, Shaw, J, Desai, S & Crosbie, EJ 2022, ' Predicting the likelihood of a BRCA1/2 pathogenic variant being somatic by testing only tumour DNA in non-mucinous high-grade epithelial ovarian cancer ', Journal Of Clinical Pathology . https://doi.org/10.1136/jcp-2022-208369

مصطلحات موضوعية: Ovarian Neoplasms, GENETICS, Manchester Cancer Research Centre, ResearchInstitutes_Networks_Beacons/mcrc, Biomarkers, Tumor, General Medicine, Pathology and Forensic Medicine

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76400a7c00ab211c13628e824ace32a4
https://www.mendeley.com/catalogue/f0b4bc28-8cbb-3b9b-a445-022fcc539057/

المؤلفون: Robert D, Morgan, George J, Burghel, Nicola, Flaum, Michael, Bulman, Philip, Smith, Andrew R, Clamp, Jurjees, Hasan, Claire, Mitchell, Zena, Salih, Emma R, Woodward, Fiona, Lalloo, Joseph, Shaw, Sudha, Desai, Emma J, Crosbie, Richard J, Edmondson, Helene, Schlecht, Andrew J, Wallace, Gordon C, Jayson, D Gareth R, Evans

المصدر: Journal of clinical pathology.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::1e535daae7f9e63db4d16f9e91368235
https://pubmed.ncbi.nlm.nih.gov/35738887

المؤلفون: Robert D. Morgan, I-Hsuan Lin, Joanne C. McGrail, Louisa Nelson, Sudha Desai, Bethany M. Barnes, George J Burghel, Anthony Tighe, Stephen S. Taylor

المصدر: Genome Medicine
Genome Medicine, Vol 13, Iss 1, Pp 1-19 (2021)
Barnes, B, Nelson, L, Tighe, A, Burghel, G, Lin, I-H, Desai, S, Mcgrail, J, Morgan, R D & Taylor, S 2021, ' Distinct transcriptional programs stratify ovarian cancer cell lines into the five major histological subtypes ', Genome Medicine, vol. 13, no. 1, 140 . https://doi.org/10.1186/s13073-021-00952-5

مصطلحات موضوعية: Prior diagnosis, Computational biology, Biology, QH426-470, Transcriptome, transcriptomics, Ovarian cancer, Cell Line, Tumor, Databases, Genetic, Machine learning, medicine, subtype classification, Genetics, Humans, Epithelial ovarian cancer, Transcriptomics, Molecular Biology, Genetics (clinical), Benzyl Alcohols, Ovarian Neoplasms, Manchester Cancer Research Centre, ResearchInstitutes_Networks_Beacons/mcrc, Gene Expression Profiling, Research, machine-learning, Computational Biology, High-Throughput Nucleotide Sequencing, Non-negative matrix factorization, RNA sequencing, medicine.disease, Human genetics, Gene Expression Regulation, Neoplastic, Serous fluid, Cell culture, Mutation, Molecular Medicine, Medicine, Female, Neoplasm Grading, Genetic Background, Clear cell, Algorithms, Subtype classification

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8668d92a4d3f4b9dbcd66b66b1f7993
http://europepmc.org/articles/PMC8408985

المؤلفون: Floris Foijer, Anthony Tighe, Louisa Nelson, Diana C.J. Spierings, René Wardenaar, George J Burghel, Bethany M. Barnes, Joanne C. McGrail, Helene Schlecht, Robert D. Morgan, Camilla Coulson-Gilmer, Sudha Desai, Stephen S. Taylor

المساهمون: Stem Cell Aging Leukemia and Lymphoma (SALL), Damage and Repair in Cancer Development and Cancer Treatment (DARE), Restoring Organ Function by Means of Regenerative Medicine (REGENERATE)

المصدر: Journal of Experimental & Clinical Cancer Research : CR
Journal of experimental & clinical cancer research, 40(1):323. BMC
Coulson-Gilmer, C, Morgan, R D, Nelson, L, Barnes, B M, Tighe, A, Wardenaar, R, Spierings, D C J, Schlecht, H, Burghel, G J, Foijer, F, Desai, S, McGrail, J C & Taylor, S S 2021, ' Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models ', Journal of Experimental and Clinical Cancer Research, vol. 40, no. 1, 323 . https://doi.org/10.1186/s13046-021-02124-0
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-26 (2021)

مصطلحات موضوعية: Cancer Research, CARCINOMA, Glycoside Hydrolases, replication stress, CELL-LINES, PROGRESSION, Disease, Gene expression signature, CHROMOSOMAL INSTABILITY, PACLITAXEL, Biology, DNA replication, gene expression signature, predictive biomarkers, Predictive biomarkers, Chromosome instability, Cell Line, Tumor, medicine, Humans, Gene, RC254-282, PARG inhibitor, Ovarian Neoplasms, CARBOPLATIN, PARG, Manchester Cancer Research Centre, MUTATIONS, ResearchInstitutes_Networks_Beacons/mcrc, Research, DNA-REPLICATION, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Replication stress, POLY(ADP-RIBOSE), Cell cycle, medicine.disease, Biomarker (cell), Oncology, Cancer research, Female, Ovarian cancer, High-grade serous ovarian cancer, RESISTANCE

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00af97bfeaa0d39fc283efc39aee3b79
https://pubmed.ncbi.nlm.nih.gov/34656146

المؤلفون: Joni Van der Meulen, W. Glenn McCluggage, Jo Van Dorpe, Nadine Van Roy, Baljeet Kaur, Sudha Desai, Koen Van de Vijver, Ellen Deolet, Iteeka Arora

المصدر: The American journal of surgical pathology. 46(1)

مصطلحات موضوعية: Adult, Pathology, medicine.medical_specialty, Serous carcinoma, Class I Phosphatidylinositol 3-Kinases, Ovary, Biology, Adenocarcinoma, medicine.disease_cause, Pathology and Forensic Medicine, Mesonephric duct, Proto-Oncogene Proteins p21(ras), Immunophenotyping, medicine, Biomarkers, Tumor, Humans, Mullerian Ducts, Peritoneal Neoplasms, Aged, Cell Proliferation, Aged, 80 and over, Ovarian Neoplasms, Germ cell neoplasm, Ovarian Endometrioid Tumor, Cell Differentiation, Wolffian Ducts, Middle Aged, medicine.disease, medicine.anatomical_structure, Treatment Outcome, Mutation, Surgery, Female, KRAS, Anatomy, Germ cell, Mesocolon

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29a3611871fe07c77d4fbaa80b7e96e
https://pubmed.ncbi.nlm.nih.gov/34183523