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المؤلفون: Phong Nguyen, Sue J. Swanson, Jyoti R. Patel, Jiahong Wang, Annika Goos-Nilsson, J.T. Link, Peer B. Jacobson, Zhenping Tian, Marlena Grynfarb, Jia Du, James M. Schmidt, Brad Zinker, Thomas W von Geldern, Steven Fung, Thomas J Reisch, Denise Wilcox, Gary Rotert, Benjamin C. Lane, Bach Hickman, Bryan Sorensen
المصدر: Journal of Medicinal Chemistry. 48:5295-5304
مصطلحات موضوعية: Male, Transcriptional Activation, Benzylamines, Hypothalamo-Hypophyseal System, medicine.medical_specialty, Side effect, Pituitary-Adrenal System, Dexamethasone, Rats, Sprague-Dawley, Mice, Radioligand Assay, chemistry.chemical_compound, Cricetulus, Receptors, Glucocorticoid, Glucocorticoid receptor, Genes, Reporter, Pregnancy, Cricetinae, Internal medicine, Drug Discovery, medicine, Animals, Humans, Hypoglycemic Agents, Receptor, Glucocorticoids, Cells, Cultured, Tyrosine Transaminase, chemistry.chemical_classification, Sulfonamides, Triglyceride, Cholesterol, Uterus, Fatty acid, Alkaline Phosphatase, Rats, medicine.anatomical_structure, Endocrinology, chemistry, Hepatocytes, Molecular Medicine, Female, Antagonism, Hypothalamic–pituitary–adrenal axis
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2
المؤلفون: David J. Grampovnik, Lynn Colletti, Dale J. Kempf, Larry L. Klein, Mulugeta Mamo, David A. Degoey, Sue J. Swanson, Kennan C. Marsh, David Morfitt, Bach Nguyen, Tatyana Dekhtyar, Warren M. Kati, Hongmei Mo, Akhteruzzaman Molla, Clinton M. Yeung, William J. Flosi, Charles A. Flentge, Hui-Ju Chen, John T. Randolph, Vincent S. Stoll, James M. Schmidt
المصدر: Journal of medicinal chemistry. 52(8)
مصطلحات موضوعية: Models, Molecular, Cell Membrane Permeability, Pyridines, Rats, Gunn, Biological Availability, Hyperlipidemias, In Vitro Techniques, Crystallography, X-Ray, Structure-Activity Relationship, Dogs, HIV Protease, In vivo, Drug Discovery, Drug Resistance, Viral, Putrescine, HIV Protease Inhibitor, Potency, Animals, Humans, Protease inhibitor (pharmacology), Hyperbilirubinemia, chemistry.chemical_classification, Binding Sites, biology, Wild type, Stereoisomerism, Dipeptides, HIV Protease Inhibitors, Bioavailability, Rats, Enzyme, Biochemistry, chemistry, Enzyme inhibitor, Mutation, biology.protein, HIV-1, Microsomes, Liver, Molecular Medicine, Carbamates, Caco-2 Cells
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3
المؤلفون: K. B. Idler, J. O. Leung, Sue J. Swanson, J. M. Weber, James B. McAlpine
المصدر: Science. 252:114-117
مصطلحات موضوعية: DNA, Bacterial, DNA Mutational Analysis, Molecular Sequence Data, Restriction Mapping, Mutant, Mixed Function Oxygenases, chemistry.chemical_compound, Bacterial Proteins, Cytochrome P-450 Enzyme System, Biosynthesis, Amino Acid Sequence, chemistry.chemical_classification, Multidisciplinary, Bacteria, Base Sequence, biology, Streptomycetaceae, Cytochrome P450, Biological activity, biology.organism_classification, Erythromycin, Enzyme, chemistry, Biochemistry, Genes, Bacterial, biology.protein, Saccharopolyspora erythraea, Actinomycetales, Plasmids
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4
المؤلفون: James B. McAlpine, Ben Lane, Valerie A. Thomas, R. A. Krause, Karl W. Mollison, Usha Premachandran, Neal S. Burres, Sue J. Swanson, Andrea Frigo, Loan N. Miller, Thomas A. Fey
المصدر: The Journal of Antibiotics. 44:1331-1341
مصطلحات موضوعية: Interleukin 2, Pharmacology, Biology, Tacrolimus, Mice, Immunophilins, Cyclosporin a, Drug Discovery, medicine, Splenocyte, Animals, Humans, Ascomycin, Mice, Inbred BALB C, Pokeweed mitogen, Biological activity, Anti-Bacterial Agents, Mice, Inbred C57BL, Biochemistry, Concanavalin A, Cyclosporine, biology.protein, Oligomycins, Lymphocyte Culture Test, Mixed, Sodium-Potassium-Exchanging ATPase, Immunosuppressive Agents, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e181b60ec0018eaf42d1337faa3015a
https://doi.org/10.7164/antibiotics.44.1331 -
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المؤلفون: Sue J. Swanson, Pauline M. Tillis, Marianna Jackson, Robert J. Theriault, Grant J. Barlow, James B. McAlpine, Dwight J. Hardy, James P. Karwowski
المصدر: The Journal of Antibiotics. 43:223-228
مصطلحات موضوعية: Pharmacology, Bacteria, biology, medicine.drug_class, Staphylococcus, Gram-positive bacteria, Antibiotics, Streptococcus, biology.organism_classification, medicine.disease_cause, Anti-Bacterial Agents, Microbiology, Aminoglycosides, Actinomycetales, Fermentation, Drug Discovery, medicine, Antibacterial activity, Soil microbiology, Soil Microbiology, Antibacterial agent
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1c52ef1550e303d00625d132a76e80
https://doi.org/10.7164/antibiotics.43.223 -
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المؤلفون: Alexander M. Buko, Sue J. Swanson, James B. McAlpine, David N. Whittern, L. M. Ranfranz, Jill E. Hochlowski
المصدر: The Journal of Antibiotics. 40:575-588
مصطلحات موضوعية: Pharmacology, Magnetic Resonance Spectroscopy, Stereochemistry, Chemistry, Spectrum Analysis, Ring (chemistry), Dactylosporangium aurantiacum, Mass Spectrometry, Homonuclear molecule, Anti-Bacterial Agents, Molecular Weight, Aminoglycosides, Heteronuclear molecule, Actinomycetales, Drug Discovery, Molecule, Glycosides, Fermentation broth, Fidaxomicin, Mycelium, Antibacterial agent
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1687eb7cb84277c7896631b2e8c8da39
https://doi.org/10.7164/antibiotics.40.575 -
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المؤلفون: Marianna Jackson, Sue J. Swanson, Robert J. Theriault, Rosita M. Villarreal, James P. Karwowski, Patrick E. Humphrey, Gabriela N. Sunga, William L. Kohl
المصدر: The Journal of Antibiotics. 42:527-532
مصطلحات موضوعية: Pharmacology, Bacteria, medicine.drug_class, Pseudomonas aeruginosa, Antibiotics, Biology, medicine.disease_cause, biology.organism_classification, Anti-Bacterial Agents, Culture Media, Microbiology, Aminoglycosides, Fermentation, Drug Discovery, Pseudomonadales, Microscopy, Electron, Scanning, medicine, Taxonomy (biology), Soil Microbiology, Organism, Pseudomonadaceae
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b98da9a71dac25517d2b6dfe194ad6
https://doi.org/10.7164/antibiotics.42.527